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Cited by 285

The DOI matches its Crossref record; 46 of the 46 references it cites were found in a registry or an index.

Visible Light-Mediated Direct Decarboxylative C–H Functionalization of Heteroarenes

Garza-Sanchez, R. Aleyda, Tlahuext-Aca, Adrian, Tavakoli, Ghazal, Glorius, Frank·2017·ACS Catalysis

Abstract

The direct visible light-mediated C–H alkylation of heteroarenes using aliphatic carboxylic acids is reported. This mild method proceeds at low catalyst loadings (0.5 mol %) and has a high functional group tolerance and a broad substrate scope. Notably, functionalization of (iso)quinoline, pyridine, phthalazine, benzothiazole, and other heterocyclic derivatives with both cyclic and acyclic primary, secondary, and tertiary carboxylic acids as well as amino and fatty acids proceeded under the standard conditions at room temperature. This protocol enables the rapid conversion of abundant feedstock materials into medically relevant “drug-like” moieties.

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Crossref · 10.1021/acscatal.7b01133

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Metadata

Authors
Garza-Sanchez, R. A., Tlahuext-Aca, A., Tavakoli, G., & Glorius, F.
Venue
ACS Catalysis
Published
2017-05-16
Volume
7
Issue
6
Pages
4057-4061
ISSN
2155-5435 (ISSN-L)
OpenAlex
W2613453516
Cited by
285
References
46
FWCI
14.93
Type
journal article
Language
en
Open access
closed

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

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