Near-Infrared-II Nanoparticles for Cancer Imaging of Immune Checkpoint Programmed Death-Ligand 1 and Photodynamic/Immune Therapy

Predictive correlates of response to the anti-PD-L1 antibody MPDL3280A in cancer patients

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MPDL3280A (anti-PD-L1) treatment leads to clinical activity in metastatic bladder cancer

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PD-L1 (B7-H1) and PD-1 pathway blockade for cancer therapy: Mechanisms, response biomarkers, and combinations

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Clearance properties of nano-sized particles and molecules as imaging agents: considerations and caveats

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A small-molecule dye for NIR-II imaging

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Photothermal therapy with immune-adjuvant nanoparticles together with checkpoint blockade for effective cancer immunotherapy

Chen, Q., Xu, L., Liang, C., Wang, C., Peng, R., & Liu, Z. (2016) · Nature Communications · doi:10.1038/ncomms13193 · Cited by 1,600 · see citing works

Assessment of the Evolution of Cancer Treatment Therapies

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89Zr-atezolizumab imaging as a non-invasive approach to assess clinical response to PD-L1 blockade in cancer

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(α-NaYbF 4 :Tm 3+ )/CaF 2 Core/Shell Nanoparticles with Efficient Near-Infrared to Near-Infrared Upconversion for High-Contrast Deep Tissue Bioimaging

Chen, G., Shen, J., Ohulchanskyy, T. Y., Patel, N. J., Kutikov, A. B., Li, Z., Song, J., Pandey, R. K., Ågren, H., Prasad, P. N., et al. (2012) · ACS Nano · doi:10.1021/nn302972r · Cited by 719 · see citing works

LSD1 Ablation Stimulates Anti-tumor Immunity and Enables Checkpoint Blockade

Sheng, W., LaFleur, M. W., Nguyen, T. H., Chen, S., Chakravarthy, A., Conway, J. R., Li, Y., Chen, H., Yang, H., Hsu, P.-H., et al. (2018) · Cell · doi:10.1016/j.cell.2018.05.052 · Cited by 693 · see citing works

Optical nano-agents in the second near-infrared window for biomedical applications

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In vivo molecular imaging for immunotherapy using ultra-bright near-infrared-IIb rare-earth nanoparticles

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Targeted zwitterionic near-infrared fluorophores for improved optical imaging

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Donor Engineering for NIR-II Molecular Fluorophores with Enhanced Fluorescent Performance

Yang, Q., Hu, Z., Zhu, S., Ma, R., Ma, H., Ma, Z., Wan, H., Zhu, T., Jiang, Z., Liu, W., et al. (2018) · Journal of the American Chemical Society · doi:10.1021/jacs.7b10334 · Cited by 554 · see citing works

Metabolism of Nanomaterials in Vivo: Blood Circulation and Organ Clearance

Wang, B., He, X. B., Zhang, Z., Zhao, Y., & Feng, W. (2012) · Accounts of Chemical Research · doi:10.1021/ar2003336 · Cited by 534 · see citing works

A bright organic NIR-II nanofluorophore for three-dimensional imaging into biological tissues

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Cell-Specific and pH-Activatable Rubyrin-Loaded Nanoparticles for Highly Selective Near-Infrared Photodynamic Therapy against Cancer

Tian, J., Ding, L., Xu, H., Shen, Z., Ju, H., Li, J., Bao, L., & Yu, J. (2013) · Journal of the American Chemical Society · doi:10.1021/ja408286k · Cited by 416 · see citing works

FcγRs Modulate the Anti-tumor Activity of Antibodies Targeting the PD-1/PD-L1 Axis

Dahan, R., Sega, E. I., Engelhardt, J., Selby, M., Korman, A. J., & Ravetch, J. V. (2015) · Cancer Cell · doi:10.1016/j.ccell.2015.08.004 · Cited by 410 · see citing works

PD-L1 is induced in hepatocytes by viral infection and by interferon-α and -γ and mediates T cell apoptosis

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Chlorin e6 Conjugated Poly(dopamine) Nanospheres as PDT/PTT Dual-Modal Therapeutic Agents for Enhanced Cancer Therapy

Zhang, D., Wu, M., Zeng, Y., Wu, L., Wang, Q., Han, X., Liu, X., & Liu, J. (2015) · ACS Applied Materials & Interfaces · doi:10.1021/acsami.5b01027 · Cited by 357 · see citing works

Glucose‐Sensitive Hydrogel Optical Fibers Functionalized with Phenylboronic Acid

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Ultralow-Power Near Infrared Lamp Light Operable Targeted Organic Nanoparticle Photodynamic Therapy

Huang, L. F., Li, Z., Zhao, Y., Zhang, Y., Wu, S., Zhao, J., & Han, G. (2016) · Journal of the American Chemical Society · doi:10.1021/jacs.6b05390 · Cited by 301 · see citing works

Engineering nanoparticles to locally activate T cells in the tumor microenvironment

Wang, D., Wang, T., Yu, H., Feng, B., Zhou, L., Zhou, F., Hou, B., Zhang, H., Luo, M., & Li, Y. (2019) · Science Immunology · doi:10.1126/sciimmunol.aau6584 · Cited by 264 · see citing works

Exerting Enhanced Permeability and Retention Effect Driven Delivery by Ultrafine Iron Oxide Nanoparticles with T1–T2 Switchable Magnetic Resonance Imaging Contrast

Wang, L., Huang, J., Chen, H., Wu, H. C., Xu, Y., Li, Y., Yi, H. L., Wang, Y. A., Yang, L. P. H., & Mao, H. Z. (2017) · ACS Nano · doi:10.1021/acsnano.7b00038 · Cited by 212 · see citing works

Combination of photodynamic therapy (PDT) and anti-tumor immunity in cancer therapy

Hwang, H. S., Shin, H., Han, J., & Na, K. (2017) · Journal of Pharmaceutical Investigation · doi:10.1007/s40005-017-0377-x · Cited by 208 · see citing works

Diketopyrrolopyrrole-based semiconducting polymer nanoparticles for in vivo second near-infrared window imaging and image-guided tumor surgery

Shou, K., Tang, Y., Chen, H., Chen, S., Zhang, L., Zhang, A., Fan, Q., Yu, A., & Cheng, Z. (2018) · Chemical Science · doi:10.1039/c8sc00206a · Cited by 199 · see citing works

A humanized antibody for imaging immune checkpoint ligand PD-L1 expression in tumors

Chatterjee, S., Lesniak, W. G., Gabrielson, M., Lisok, A., Wharram, B. L., Sysa‐Shah, P., Azad, B. B., Pomper, M. G., & Nimmagadda, S. (2016) · Oncotarget · doi:10.18632/oncotarget.7143 · Cited by 194 · see citing works

Boron Dipyrromethene Nano‐Photosensitizers for Anticancer Phototherapies

Sun, W. C., Zhao, X., Fan, J., Du, J., & Peng, X. (2019) · Small · doi:10.1002/smll.201804927 · Cited by 178 · see citing works

Deciphering the intersystem crossing in near-infrared BODIPY photosensitizers for highly efficient photodynamic therapy

Miao, X., Hu, W., He, T., Tao, H., Wang, Q., Chen, R., Jin, L., Zhao, H., Lü, X., Fan, Q., et al. (2019) · Chemical Science · doi:10.1039/c8sc04840a · Cited by 165 · see citing works

Multifunctional AIEgens for Future Theranostics

Feng, G., & Liu, B. (2016) · Small · doi:10.1002/smll.201601637 · Cited by 151 · see citing works

Biocompatible small organic molecule phototheranostics for NIR-II fluorescence/photoacoustic imaging and simultaneous photodynamic/photothermal combination therapy

Wang, Q., Xia, B., Xu, J., Niu, X., Cai, J., Shen, Q., Wang, W., Huang, W., & Fan, Q. (2019) · Materials Chemistry Frontiers · doi:10.1039/c9qm00036d · Cited by 127 · see citing works

Second near-infrared photodynamic therapy and chemotherapy of orthotopic malignant glioblastoma with ultra-small Cu 2−x Se nanoparticles

Zhang, H., Wang, T., Liu, H., Ren, F. Z., Qiu, W., Sun, Q., Yan, F., Zheng, H., Li, Z., & Gao, M. (2019) · Nanoscale · doi:10.1039/c9nr01789e · Cited by 126 · see citing works

Fluorescence Imaging In Vivo at Wavelengths beyond 1500 nm

Diao, S., Blackburn, J. L., Hong, G., Antaris, A. L., Chang, J., Wu, J. Z., Zhang, B., Cheng, K., Kuo, C. J., & Dai, H. (2015) · Angewandte Chemie · doi:10.1002/ange.201507473 · Cited by 122 · see citing works

Fabrication of Red Blood Cell-Based Multimodal Theranostic Probes for Second Near-Infrared Window Fluorescence Imaging-Guided Tumor Surgery and Photodynamic Therapy

Wang, P., Wang, X., Luo, Q., Li, Y., Lin, X., Fan, L., Zhang, Y., Liu, J., & Liu, X. (2019) · Theranostics · doi:10.7150/thno.29817 · Cited by 121 · see citing works

Developing a Bright NIR‐II Fluorophore with Fast Renal Excretion and Its Application in Molecular Imaging of Immune Checkpoint PD‐L1

Wan, H., Ma, H., Zhu, S., Wang, F., Tian, Y., Ma, R., Yang, Q., Hu, Z., Zhu, T., Wang, W., et al. (2018) · Advanced Functional Materials · doi:10.1002/adfm.201804956 · Cited by 120 · see citing works

Enhanced Anti-Tumor Efficacy through a Combination of Integrin αvβ6-Targeted Photodynamic Therapy and Immune Checkpoint Inhibition

Gao, L., Zhang, C., Gao, D., Liu, H., Yu, X., Lai, J., Wang, F., Lin, J., & Liu, Z. (2016) · Theranostics · doi:10.7150/thno.14792 · Cited by 111 · see citing works

Systemic Antitumor Immunity by PD-1/PD-L1 Inhibition Is Potentiated by Vascular-Targeted Photodynamic Therapy of Primary Tumors

O’Shaughnessy, M. J., Murray, K. S., Rosa, S. P. L., Budhu, S., Merghoub, T., Somma, A. J., Monette, S., Kim, K., Corradi, R. B., Scherz, A. J., et al. (2017) · Clinical Cancer Research · doi:10.1158/1078-0432.ccr-17-0186 · Cited by 99 · see citing works

Near-Infrared Organic Single-Crystal Nanolaser Arrays Activated by Excited-State Intramolecular Proton Transfer

Wu, J., Gao, H., Lai, R., Zhuo, M., Feng, J., Wang, X., Wu, Y., Liao, L., & Jiang, L. (2020) · Matter · doi:10.1016/j.matt.2020.01.023 · Cited by 93 · see citing works

A theranostic agent for cancer therapy and imaging in the second near-infrared window

Ma, Z., Wan, H., Wang, W., Zhang, X., Uno, T., Yang, Q., Yue, J., Gao, H., Zhong, Y., Tian, Y., et al. (2018) · Nano Research · doi:10.1007/s12274-018-2210-x · Cited by 92 · see citing works

Imaging of Programmed Cell Death Ligand 1: Impact of Protein Concentration on Distribution of Anti-PD-L1 SPECT Agents in an Immunocompetent Murine Model of Melanoma

Nedrow, J. R., Josefsson, A., Park, S., Ranka, S., Roy, S., & Sgouros, G. (2017) · Journal of Nuclear Medicine · doi:10.2967/jnumed.117.193268 · Cited by 84 · see citing works

Expression of PD-1, PD-L1, and PD-L2 in the Liver in Autoimmune Liver Diseases

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Tuning the photo-physical properties of BODIPY dyes: Effects of 1, 3, 5, 7- substitution on their optical and electrochemical behaviours

Tao, J., Sun, D., Sun, L., Li, Z., Fu, B., Liu, J., Zhang, L., Wang, S., Fang, Y., & Xu, H. (2019) · Dyes and Pigments · doi:10.1016/j.dyepig.2019.04.054 · Cited by 78 · see citing works

Cancer immunotherapy via combining oncolytic virotherapy with chemotherapy: recent advances

Pandha, H., Simpson, G. R., Relph, K., Melcher, A. A., & Harrington, K. J. (2016) · Oncolytic Virotherapy · doi:10.2147/ov.s66083 · Cited by 77 · see citing works

Functionalized Flexible Soft Polymer Optical Fibers for Laser Photomedicine

Jiang, N., Ahmed, R., Aoni, R. A., Guo, J., Yin, Y., Montelongo, Y., Butt, H., & Yetisen, A. K. (2017) · Advanced Optical Materials · doi:10.1002/adom.201701118 · Cited by 73 · see citing works

Modulating PD-L1 expression in multiple myeloma: an alternative strategy to target the PD-1/PD-L1 pathway

Tremblay-LeMay, R., Rastgoo, N., & Chang, H. (2018) · Journal of Hematology & Oncology · doi:10.1186/s13045-018-0589-1 · Cited by 69 · see citing works

BODIPY-doped silica nanoparticles with reduced dye leakage and enhanced singlet oxygen generation

Wang, Z., Hong, X., Zong, S., Tang, C., Cui, Y., & Zheng, Q. (2015) · Scientific Reports · doi:10.1038/srep12602 · Cited by 68 · see citing works

Noninvasive Imaging of Immune Checkpoint Ligand PD-L1 in Tumors and Metastases for Guiding Immunotherapy

Chatterjee, S., Lesniak, W. G., & Nimmagadda, S. (2017) · Molecular Imaging · doi:10.1177/1536012117718459 · Cited by 61 · see citing works

PD-L1 Signal on Liver Dendritic Cells Is Critical for Foxp3+CD4+CD25+ Treg and Liver Tolerance Induction in Mice

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Increased CD86 but Not CD80 and PD-L1 Expression on Liver CD68+ Cells during Chronic HBV Infection

Said, E. A., Al‐Reesi, I., Al-Riyami, M., Al-Naamani, K. M., Al-Sinawi, S., Al-Balushi, M. S., Koh, C. Y., Al-Busaidi, J. Z., Idris, M. A., & Al-Jabri, A. A. (2016) · PLoS ONE · doi:10.1371/journal.pone.0158265 · Cited by 32 · see citing works

Overcoming barriers in photodynamic therapy harnessing nano-formulation strategies

Xie, J., Wang, Y., Choi, W., Jangili, P., Ge, Y., Xu, Y., Kang, J., Liu, L., Zhang, B., Xie, Z., et al. (2021) · Chemical Society Reviews · doi:10.1039/d0cs01370f · Cited by 526 · see citing works

Cancer nanotechnology: current status and perspectives

Kemp, J. A., & Kwon, Y. J. (2021) · Nano Convergence · doi:10.1186/s40580-021-00282-7 · Cited by 277 · see citing works

BODIPY as a Multifunctional Theranostic Reagent in Biomedicine: Self‐Assembly, Properties, and Applications

Cheng, H., Cao, X., Zhang, S., Zhang, K., Cheng, Y., Wang, J., Zhao, J., Zhou, L., Liang, X., & Yoon, J. (2022) · Advanced Materials · doi:10.1002/adma.202207546 · Cited by 264 · see citing works

Research advances in BODIPY-assembled supramolecular photosensitizers for photodynamic therapy

Wang, J., Gong, Q., Jiao, L., & Hao, E. (2023) · Coordination Chemistry Reviews · doi:10.1016/j.ccr.2023.215367 · Cited by 188 · see citing works

Recent progress in NIR-II fluorescence imaging-guided drug delivery for cancer theranostics

Roy, S., Bag, N., Bardhan, S., Hasan, I., & Guo, B. (2023) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2023.114821 · Cited by 183 · see citing works

J‐Aggregation Strategy toward Potentiated NIR‐II Fluorescence Bioimaging of Molecular Fluorophores

Hu, X., Zhu, C., Sun, F., Chen, Z., Zou, J., Chen, X. S., & Yáng, Z. (2023) · Advanced Materials · doi:10.1002/adma.202304848 · Cited by 180 · see citing works

Engineering of BODIPY-based theranostics for cancer therapy

Mao, Z., Kim, J. H., Lee, J., Xiong, H., Zhang, F., & Kim, J. S. (2022) · Coordination Chemistry Reviews · doi:10.1016/j.ccr.2022.214908 · Cited by 159 · see citing works

A Self-Cascade Penetrating Brain Tumor Immunotherapy Mediated by Near-Infrared II Cell Membrane-Disrupting Nanoflakes via Detained Dendritic Cells

Yalamandala, B. N., Chen, Y.-J., Lin, Y., Huynh, T. M. H., Chiang, W., Chou, T., Liu, H.-W., Huang, C., Lin, Y.-J., Chiang, C., et al. (2024) · ACS Nano · doi:10.1021/acsnano.4c06183 · Cited by 122 · see citing works

Nanomaterials for light-mediated therapeutics in deep tissue

Tsang, C. Y., & Zhang, Y. (2024) · Chemical Society Reviews · doi:10.1039/d3cs00862b · Cited by 117 · see citing works

Design, synthesis and functionalization of BODIPY dyes: applications in dye-sensitized solar cells (DSSCs) and photodynamic therapy (PDT)

Yadav, I. S., & Misra, R. (2023) · Journal of Materials Chemistry C · doi:10.1039/d3tc00171g · Cited by 113 · see citing works

NIR‐II Organic Nanotheranostics for Precision Oncotherapy

Dai, H., Wang, X., Shao, J., Wang, W., Mou, X., & Dong, X. (2021) · Small · doi:10.1002/smll.202102646 · Cited by 110 · see citing works

Immuno-photodynamic Therapy (IPDT): Organic Photosensitizers and Their Application in Cancer Ablation

Yang, L. G., Sun, W. C., Du, J., Fan, J., & Peng, X. (2023) · JACS Au · doi:10.1021/jacsau.2c00591 · Cited by 105 · see citing works

Immunogenic cell death inducers for enhanced cancer immunotherapy

Li, Y., Liu, X., Zhang, X., Pan, W., Li, N., & Tang, B. (2021) · Chemical Communications · doi:10.1039/d1cc04604g · Cited by 96 · see citing works

Boosting Checkpoint Immunotherapy with Biomaterials

Liu, L., Pan, Y., Zhao, C., Huang, P., Chen, X. S., & Rao, L. (2023) · ACS Nano · doi:10.1021/acsnano.2c11691 · Cited by 96 · see citing works

Tracking tumor heterogeneity and progression with near‐infrared II fluorophores

Qi, X., Ma, H., Wang, H., & Zhang, X. (2023) · Exploration · doi:10.1002/exp.20220011 · Cited by 95 · see citing works

Nanoprobe-based molecular imaging for tumor stratification

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Sensing, Imaging, and Therapeutic Strategies Endowing by Conjugate Polymers for Precision Medicine

Shen, Q., Song, G., Lin, H., Bai, H., Huang, Y., Lv, F., & Wang, S. (2024) · Advanced Materials · doi:10.1002/adma.202310032 · Cited by 89 · see citing works

Oxidation-Responsive PolyMOF Nanoparticles for Combination Photodynamic-Immunotherapy with Enhanced STING Activation

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Advances in nanoparticles-based approaches in cancer theranostics

Raheem, M. A., Rahim, M. A., Gul, I., Zhong, X., Xiao, C., Zhang, H., Wei, J., He, Q., Hassan, M. A., Zhang, C. Y., et al. (2023) · OpenNano · doi:10.1016/j.onano.2023.100152 · Cited by 85 · see citing works

Current Strategies for Tumor Photodynamic Therapy Combined With Immunotherapy

Hua, J., Wu, P., Gan, L., Zhang, Z., He, J., Zhong, L., Zhao, Y., & Huang, Y. (2021) · Frontiers in Oncology · doi:10.3389/fonc.2021.738323 · Cited by 79 · see citing works

Multi-site isomerization of synergistically regulated stimuli-responsive AIE materials toward multi-level decryption

Zhong, W., Zhang, J., Lin, Y., Li, S., Yang, Y., Wang, W., Si, C., Kühn, F. E., Zhao, Z., Cai, X., et al. (2024) · Chemical Science · doi:10.1039/d3sc06191d · Cited by 77 · see citing works

Crucial Breakthrough of BODIPY‐Based NIR‐II Fluorescent Emitters for Advanced Biomedical Theranostics

Hu, X., Fang, Z.-T., Zhu, C., Yang, Y., Yáng, Z., & Huang, W. (2024) · Advanced Functional Materials · doi:10.1002/adfm.202401325 · Cited by 77 · see citing works

Nano Drug Delivery System for Tumor Immunotherapy: Next-Generation Therapeutics

Zhou, L., Zou, M., Xu, Y., Lin, P., Lei, C., & Xia, X. (2022) · Frontiers in Oncology · doi:10.3389/fonc.2022.864301 · Cited by 76 · see citing works

A Tumor‐Microenvironment‐Activatable Molecular Pro‐Theranostic Agent for Photodynamic and Immunotherapy of Cancer

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Harnessing immune response using reactive oxygen Species-Generating/Eliminating inorganic biomaterials for disease treatment

Zhao, C., Deng, H., & Chen, X. S. (2022) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2022.114456 · Cited by 69 · see citing works

Redox regulation and its emerging roles in cancer treatment

Zhang, H., Mao, Z., Kang, Y., Zhang, W., Mei, L., & Ji, X. (2022) · Coordination Chemistry Reviews · doi:10.1016/j.ccr.2022.214897 · Cited by 66 · see citing works

Supramolecular assembly boosting the phototherapy performances of BODIPYs

Dai, Y., Sun, J., Zhang, X., Zhao, J., Yang, W., Zhou, J., Gao, Z., Wang, Q., Yu, F., & Wang, B. (2024) · Coordination Chemistry Reviews · doi:10.1016/j.ccr.2024.216054 · Cited by 64 · see citing works

Nanoparticle-based drug delivery systems to enhance cancer immunotherapy in solid tumors

Zhang, J., Wang, S., Zhang, D. D., He, X., Wang, X. B., Han, H., & Qin, Y. (2023) · Frontiers in Immunology · doi:10.3389/fimmu.2023.1230893 · Cited by 56 · see citing works

Leveraging BODIPY nanomaterials for enhanced tumor photothermal therapy

Ma, C., Zhang, T., & Xie, Z. (2021) · Journal of Materials Chemistry B · doi:10.1039/d1tb00855b · Cited by 55 · see citing works

A Schiff base-functionalized graphene quantum dot nanocomposite for preferable picric acid sensing

Fan, Y., Tao, T., Wang, H., Liu, Z., Huang, W., & Cao, H. (2021) · Dyes and Pigments · doi:10.1016/j.dyepig.2021.109355 · Cited by 46 · see citing works

NIR-activated multifunctional agents for the combined application in cancer imaging and therapy

Repetowski, P., Warszyńska, M., & Dąbrowski, J. M. (2024) · Advances in Colloid and Interface Science · doi:10.1016/j.cis.2024.103356 · Cited by 45 · see citing works

Chemiluminescence resonance energy transfer-based immunostimulatory nanoparticles for sonoimmunotherapy

Jeon, J., Yoon, B., Song, S. H., Um, W., Song, Y., Lee, J., You, D. G., An, J. Y., & Park, J. H. (2022) · Biomaterials · doi:10.1016/j.biomaterials.2022.121466 · Cited by 44 · see citing works

Emerging Biomaterials Imaging Antitumor Immune Response

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Catalytic Biomaterials and Nanomedicines with Exogenous and Endogenous Activations

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Development of artesunate intelligent prodrug liposomes based on mitochondrial targeting strategy

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Unveiling cellular mysteries: Advances in BODIPY dyes for subcellular imaging

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BODIPY dyes: Versatile building blocks to construct multiple types of self-assembled structures

Matarranz, B., & Fernández, G. (2021) · Chemical Physics Reviews · doi:10.1063/5.0065873 · Cited by 39 · see citing works

Photosensitizer‐Polypeptide Conjugate for Effective Elimination of Candida albicans Biofilm

Wan, P., Guo, W., Wang, Y., Deng, M., Xiao, C., & Chen, X. (2022) · Advanced Healthcare Materials · doi:10.1002/adhm.202200268 · Cited by 40 · see citing works

Recent advances in light-triggered cancer immunotherapy

Yang, J., Kwon, H., & Kim, S. (2024) · Journal of Materials Chemistry B · doi:10.1039/d3tb02842a · Cited by 38 · see citing works

Plasmonic nanomaterials: A versatile phototheranostic platform of cancers

He, Z., Zhang, C. Y., Lei, Y., Song, G., & Yao, Y. (2022) · Materials Today · doi:10.1016/j.mattod.2022.11.011 · Cited by 36 · see citing works

Carbon dots inspired by structure-inherent targeting for nucleic acid imaging and localized photodynamic therapy

Xu, N., Du, J., Yao, Q., Ge, H., Shi, C., Xu, F., Xian, L., Fan, J., & Peng, X. (2021) · Sensors and Actuators B Chemical · doi:10.1016/j.snb.2021.130322 · Cited by 34 · see citing works

Miniature NIR‐II Nanoprobes for Active‐Targeted Phototheranostics of Brain Tumors

Wu, Y., Hu, D., Gao, D., Liu, C., Zheng, H., & Sheng, Z. (2022) · Advanced Healthcare Materials · doi:10.1002/adhm.202202379 · Cited by 34 · see citing works

Targeting-specific Nanoprobes in the Second Near-infrared Window for Biomedical Applications

Guo, Y., Li, Z., Guo, B., Wang, B., & Tu, Y. (2024) · Nano Biomedicine and Engineering · doi:10.26599/nbe.2024.9290061 · Cited by 33 · see citing works

A SOCT-ISC type photosensitizer coumarin-BODIPY promoted by AIE effect: Mechanism of singlet oxygen generation, simulated PDT in A-549 cells and fluorescence imaging in zebrafish

Wang, L., & Qian, Y. (2021) · Dyes and Pigments · doi:10.1016/j.dyepig.2021.109711 · Cited by 30 · see citing works

A self-assembled nanoplatform based on Ag2S quantum dots and tellurium nanorods for combined chemo-photothermal therapy guided by H2O2-activated near-infrared-II fluorescence imaging

Li, C.-Q., Ma, M., Zhang, B., Chen, W., Yin, Z., Xie, X., Hou, X. L., Zhao, Y., & Liu, B. (2021) · Acta Biomaterialia · doi:10.1016/j.actbio.2021.12.013 · Cited by 29 · see citing works

Targeting the PD-1/PD-L1 axis for cancer treatment: a review on nanotechnology

Tran, T. H., & Tran, T. T. P. (2022) · Royal Society Open Science · doi:10.1098/rsos.211991 · Cited by 28 · see citing works

Anion receptor-mediated multicomponent synergistic self-assembly of porphyrin for efficient phototherapy to elicit tumor immunotherapy

Wang, K., Chen, J., Lin, L., Yan, N., Yang, W., Cai, K., Tian, H., & Chen, X. (2022) · Nano Today · doi:10.1016/j.nantod.2022.101579 · Cited by 28 · see citing works

Platelet membrane camouflaged AIEgen ‐mediated photodynamic therapy improves the effectiveness of anti‐PD‐L1 immunotherapy in large‐burden tumors

Dai, J., Wu, M., Xu, Y., Yao, H., Lou, X., Hong, Y., Zhou, J. Q., Xia, F., & Wang, S. (2022) · Bioengineering & Translational Medicine · doi:10.1002/btm2.10417 · Cited by 28 · see citing works

Near-infrared BODIPY-based theranostic agents for photothermal and combinatory therapy of cancers, where do we stand in year 2025

Iqbal, M. S., Ahmad, H., Chen, Y., Huang, H., & Guo, B. (2025) · Coordination Chemistry Reviews · doi:10.1016/j.ccr.2025.216781 · Cited by 27 · see citing works

Polymersome Nanoreactor‐Mediated Combination Chemodynamic‐Immunotherapy via ROS Production and Enhanced STING Activation

Zhou, Q., Wang, Y., Li, X., Lu, N., & Ge, Z. (2021) · Advanced Therapeutics · doi:10.1002/adtp.202100130 · Cited by 25 · see citing works

J-aggregates of Br- and piperazine-modified cyanine dye with the assistance of amphiphilic polypeptides for efficient NIR-IIa phototheranostics under 1064 nm irradiation

Teng, C., Dang, H., Zhang, S., Xu, Y., Yin, D., & Yan, L. (2022) · Acta Biomaterialia · doi:10.1016/j.actbio.2022.10.025 · Cited by 25 · see citing works

BODIPY Dyes: A New Frontier in Cellular Imaging and Theragnostic Applications

Kumar, P. P. P., Saxena, S., & Joshi, R. (2025) · Colorants · doi:10.3390/colorants4020013 · Cited by 24 · see citing works

BODIPY and 2,3-Dihydrophthalazine-1,4-Dione Conjugates As Heavy Atom-Free Chemiluminogenic Photosensitizers

Degirmenci, A., Sonkaya, Ö., Soylukan, C., Karaduman, T., & Algı, F. (2021) · ACS Applied Bio Materials · doi:10.1021/acsabm.1c00328 · Cited by 24 · see citing works

Optical functional nanomaterials for cancer photoimmunotherapy

Liu, L., Pan, Y., Ye, L., Liang, C., Mou, X., Dong, X., & Cai, Y. (2024) · Coordination Chemistry Reviews · doi:10.1016/j.ccr.2024.216006 · Cited by 23 · see citing works

Stimuli‐Responsive Hybrid Vesicle for Tumor Dual‐Model NIR‐II Photoacoustic and Fluorescence Imaging and Precise Radiotherapy

Lv, N., Zhang, X., Wang, S., Wu, Y., Ge, X., Song, J., Ma, Q., & Gao, S. Q. (2022) · Advanced Optical Materials · doi:10.1002/adom.202200694 · Cited by 22 · see citing works

Imaging and monitoring of granzyme B in the immune response

Li, X., Chen, G., Wu, K., Zheng, H., Tian, Z., Xu, Z. Q., Zhao, W., Weng, J., & Min, Y. (2023) · Wiley Interdisciplinary Reviews Nanomedicine and Nanobiotechnology · doi:10.1002/wnan.1928 · Cited by 21 · see citing works

Rational Modulation Strategies to Improve Bioimaging Applications for Organic NIR‐II Fluorophores

Wang, Z., She, M., Chen, J., Cheng, Z.-Q., & Li, J. (2021) · Advanced Optical Materials · doi:10.1002/adom.202101634 · Cited by 22 · see citing works

Engineered Nanoprobes for Immune Activation Monitoring

Zhou, M., Liang, S., Liu, D., Ma, K., Peng, Y., & Wang, Z. (2022) · ACS Nano · doi:10.1021/acsnano.2c09743 · Cited by 21 · see citing works

Heavy-Atom-Free Nanoparticles Based on Boron Dipyrromethene Derivatives for Combined Photothermal and Photodynamic Cancer Therapy

Li, C., Sun, T., Li, X., & Xie, Z. (2022) · ACS Applied Nano Materials · doi:10.1021/acsanm.2c04459 · Cited by 21 · see citing works

A near-infrared and lysosome-targeted coumarin-BODIPY photosensitizer for photodynamic therapy against HepG2 cells

Li, P., Zhang, W., Wang, Y., Tian, J., Shi, D., & Xu, H. (2023) · Journal of Photochemistry and Photobiology A Chemistry · doi:10.1016/j.jphotochem.2023.114735 · Cited by 20 · see citing works

High contrast 3-D optical bioimaging using molecular and nanoprobes optically responsive to IR light

Qian, J., Feng, Z., Fan, X., Kuzmin, A. N., Gomes, A. S. L., & Prasad, P. N. (2022) · Physics Reports · doi:10.1016/j.physrep.2022.02.004 · Cited by 20 · see citing works

A Self-Immobilizing Photosensitizer with Long-Term Retention for Hypoxia Imaging and Enhanced Photodynamic Therapy

Zhu, Z., Feng, Y., Tian, Q., Li, J. G., Liu, C., Cheng, Y., Zhang, S., Dang, Y., Gao, J., Lai, Y., et al. (2024) · JACS Au · doi:10.1021/jacsau.4c00787 · Cited by 19 · see citing works

A Small‐Molecule Diketopyrrolopyrrole‐Based Dye for in vivo NIR‐IIa Fluorescence Bioimaging

Yang, Z., Fan, X., Li, H., Li, X., Li, S., Zhang, Z., Lin, H. M., Qian, J., & Hua, J. (2021) · Chemistry - A European Journal · doi:10.1002/chem.202102312 · Cited by 19 · see citing works

Exploring the Potential of Gold Nanoparticles in Proton Therapy: Mechanisms, Advances, and Clinical Horizons

Carbone, G. G., Mariano, S., Gabriele, A., Cennamo, S., Primiceri, V., Aziz, M. R., Panzarini, E., & Calcagnile, L. (2025) · Pharmaceutics · doi:10.3390/pharmaceutics17020176 · Cited by 18 · see citing works

Second near-infrared nanomaterials for cancer photothermal immunotherapy

Shang, H., Wu, J., Liu, X., Tong, Y., He, Y. T., Huang, Q., Xia, D., Peng, E., Chen, Z., & Tang, K. (2022) · Materials Today Advances · doi:10.1016/j.mtadv.2022.100339 · Cited by 18 · see citing works

Bioinspired Dual‐Ionic‐Site Single‐Atom Nanozymes for Synergistic Ferroptosis/Cuproptosis and Enhanced Immune Checkpoint Blockade Therapy

Yang, L., Pan, M., Hu, H., Liu, F., Jiang, M., Ning, S., Chen, X., Zhang, Z., Yu, X., & Xu, L. (2025) · Small · doi:10.1002/smll.202501076 · Cited by 22 · see citing works

Diagnostic Radionuclides Labeled on Biomimetic Nanoparticles for Enhanced Follow‐Up Photothermal Therapy of Cancer

Yi, X., Shen, M., Liu, X., Gu, J., Jiang, Z., Xu, L., & Yang, K. (2021) · Advanced Healthcare Materials · doi:10.1002/adhm.202100860 · Cited by 17 · see citing works

Self-Assembled BODIPY Nanoparticles for Near-Infrared Fluorescence Bioimaging

Wang, J., Jiang, Z. L., Huang, C., Zhao, S., Zhu, S., Liu, R., & Zhu, H. (2023) · Molecules · doi:10.3390/molecules28072997 · Cited by 17 · see citing works

A β-cyclodextrin-based supramolecular modular system creating micellar carriers for codelivery of doxorubicin and siRNA for potential combined chemotherapy and immunotherapy

Tang, X., Wen, Y., Zhang, Z., Song, X., Zhu, J., Tian, X., & Li, J. (2024) · Carbohydrate Polymers · doi:10.1016/j.carbpol.2024.123202 · Cited by 17 · see citing works

Organic small-molecule NIR-II fluorophores for tumor phototheranostics

Xiang, D., Wang, Z., Zheng, H., Tang, Y., & Li, Q. (2026) · Light: Science & Applications · doi:10.1038/s41377-026-02212-w · Cited by 22 · see citing works

Bifunctional black phosphorus quantum dots platform: Delivery and remarkable immunotherapy enhancement of STING agonist

Zhang, Y., Wang, S., Rha, H., Xu, C., Pei, Y., Ji, X., Zhang, J., Lu, R., Zhang, S., Xie, Z., et al. (2024) · Biomaterials · doi:10.1016/j.biomaterials.2024.122696 · Cited by 16 · see citing works

Streamlined construction of boron-stereogenic BODIPY library for near-infrared bioimaging

Zhao, J., Ren, L., Lan, D., Zhan, B., Zhang, J., Mu, J., & He, C. (2025) · Nature Communications · doi:10.1038/s41467-025-64709-z · Cited by 16 · see citing works

A tumor microenvironment responsive mesoporous polydopamine theranostic probe embedded with Gd/I-doped carbon nanodots for CT/MR/FL imaging and chemo/photothermal synergistic therapy

Zhao, J., Dai, D., Zhou, L., Yu, Z., Ma, J., Yang, M., & Yi, C. (2024) · Carbon · doi:10.1016/j.carbon.2024.119065 · Cited by 16 · see citing works

A new acridine-based photosensitizer with ultra-low light requirement efficiently inactivates carbapenem-resistant Acinetobacter baumannii and methicillin-resistant Staphylococcus aureus and degrades their antibiotic resistance genes

Xu, X., Yang, M., Jiang, Y., Tao, N., Fu, Y., Fan, J., Xu, X., Shi, H., Lu, Z. L., & Shen, C. (2023) · Environment International · doi:10.1016/j.envint.2023.107839 · Cited by 14 · see citing works

Self-assembled nanoplatforms for cancer immunotherapy: Principles, progress and perspectives

Xu, W., Zhu, S., Sun, Z., Ye, J., & Chu, H. (2025) · Acta Pharmaceutica Sinica B · doi:10.1016/j.apsb.2025.06.011 · Cited by 13 · see citing works

Photosensitizer-singlet oxygen sensor conjugated silica nanoparticles for photodynamic therapy and bioimaging

Sobhanan, J., Ono, K., Okamoto, T., Sawada, M., Weiss, P. S., & Biju, V. (2023) · Chemical Science · doi:10.1039/d3sc03877g · Cited by 12 · see citing works

Halogen-substituted meso-BODIPY ethers as effective photosensitizers for antimycotic photodynamic therapy

Гусева, Г. Б., Lapshina, E. N., Antina, E. V., Eremeeva, Y. V., Lisovskaya, S. А., Izmailov, A., & Nikitina, L. E. (2024) · Journal of Photochemistry and Photobiology A Chemistry · doi:10.1016/j.jphotochem.2024.115700 · Cited by 12 · see citing works

Nanotherapeutics for immune network modulation in tumor microenvironments

Lee, J., Kim, D.-Y., Le, Q., & Oh, Y. (2021) · Seminars in Cancer Biology · doi:10.1016/j.semcancer.2021.11.005 · Cited by 12 · see citing works

Synthesis, spectroscopic characterization, one and two-photon absorption properties of β-β linked BODIPY dimers

Wang, Y., Rousselin, Y., Gros, C. P., Bolze, F., Liang, X., Zhu, W., & Xu, H. (2022) · Dyes and Pigments · doi:10.1016/j.dyepig.2022.110601 · Cited by 12 · see citing works

Perovskite-derived pro-photosensitizer enables sustainable photodynamic therapy in hypoxia tumors

Cheng, H., Chen, X., Sheng, Y., Song, M., Sun, C., Wang, Z., Zhou, J., Zhang, H., & Ding, Y. (2023) · Chemical Engineering Journal · doi:10.1016/j.cej.2023.143457 · Cited by 11 · see citing works

Synthesis of Multifunctional Nanoparticles for the Combination of Photodynamic Therapy and Immunotherapy

Lee, M., Thomas, J. L., Li, J.-A., Chen, J.-R., Wang, T.-L., & Lin, H. (2021) · Pharmaceuticals · doi:10.3390/ph14060508 · Cited by 11 · see citing works

Antitumor Effect and Induced Immune Response Following Exposure of Hexaminolevulinate and Blue Light in Combination with Checkpoint Inhibitor in an Orthotopic Model of Rat Bladder Cancer

Lamy, L., Thomas, J., Leroux, A., Bisson, J., Myren, K., Godál, A., Stensrud, G., & Bezdetnaya, L. (2022) · Biomedicines · doi:10.3390/biomedicines10030548 · Cited by 10 · see citing works

Polyamidoamine Dendrimer-Modified Near Infrared-II Fluorescent Conjugated Polymer Brush for Photodynamic/Gas Therapy

Du, X., He, K., Jiang, X., Chen, S., Zhang, R., Sun, P., & Fan, Q. (2022) · ACS Applied Polymer Materials · doi:10.1021/acsapm.2c00638 · Cited by 10 · see citing works

A type I and II compatible vinyl-pyridine modified BODIPY dimer photosensitizer for photodynamic therapy in A-549 cells

Wang, L., & Qian, Y. (2023) · Organic & Biomolecular Chemistry · doi:10.1039/d3ob01130e · Cited by 10 · see citing works

Progress of near-infrared-II fluorescence in precision diagnosis and treatment of colorectal cancer

Wu, Y., Cao, H., Yang, S., Liu, C., & Han, Z. (2023) · Heliyon · doi:10.1016/j.heliyon.2023.e23209 · Cited by 10 · see citing works

Molecular Design for Stable Near-Infrared-II Two-Photon Excitation-Induced Photoacoustic Contrast Agents Based on Donor-Substituted BODIPYs

Shimada, T., Kaneko, T., Notsuka, Y., Kim, J., Mori, S., Shimizu, S., Kim, J., Kamada, K., Kim, D., Yamaoka, Y., et al. (2024) · ACS Applied Optical Materials · doi:10.1021/acsaom.3c00400 · Cited by 10 · see citing works

A multi-parameter-induced activation of gas therapeutic platform to remarkably amplify photodynamic therapy efficacy

Sun, J., Zhang, Z., Wu, H., Dong, X., Dong, C., Sun, L., Guo, Z., Liu, Y., Gu, X., & Zhao, C. (2024) · Science China Chemistry · doi:10.1007/s11426-024-2082-6 · Cited by 9 · see citing works

Iodine-containing materials for biomedical applications

Zeng, J., Wang, Z., & Wu, F. (2025) · Journal of Materials Chemistry B · doi:10.1039/d5tb00534e · Cited by 9 · see citing works

Imaging strategies for monitoring the immune response

Liu, X., Pan, L., Wang, K., Pan, W., Li, N., & Tang, B. (2022) · Chemical Science · doi:10.1039/d2sc03446h · Cited by 9 · see citing works

Monitoring Immunotherapy With Optical Molecular Imaging

Xu, L., Wang, Y., Ma, Y., Huan, S., & Song, G. (2021) · ChemMedChem · doi:10.1002/cmdc.202100260 · Cited by 9 · see citing works

Near Infrared-Responsive Xanthene Probes for Dual-Mode Cancer Treatment and Bioimaging

Zhang, J. J., Jin, L., Xiao, B., Kim, D., Hua, S., Hua, Y., Liu, Y., Huang, X., Kou, J., Liu, B., et al. (2025) · Analytical Chemistry · doi:10.1021/acs.analchem.5c02888 · Cited by 8 · see citing works

A generic platform for self-illuminating unimolecular systems enabling photodynamic therapy

Toksoy, A., Pekcan, S., Susam, A., Erkan, D. S., Algı, M. P., & Algı, F. (2023) · Dyes and Pigments · doi:10.1016/j.dyepig.2023.111577 · Cited by 8 · see citing works

GSH-responsive bithiophene Aza-BODIPY@HMON nanoplatform for achieving triple-synergistic photoimmunotherapy

Yang, S., Hu, X., Yong, Z., Dou, Q., Quan, C., Cheng, H., Zhang, M., & Wang, J. (2024) · Colloids and Surfaces B Biointerfaces · doi:10.1016/j.colsurfb.2024.114109 · Cited by 8 · see citing works

Recent Trends and Opportunities for the Targeted Immuno-Nanomaterials for Cancer Theranostics Applications

John, C., Jain, K., Masanam, H. B., Narasimhan, A. K., & Natarajan, A. (2022) · Micromachines · doi:10.3390/mi13122217 · Cited by 8 · see citing works

H 2 O 2 self-supplying nanoparticles for chemodynamic and synergistic photodynamic therapy to augment cGAS/STING activation

Zhang, A.-H., Kong, W., Zhang, X., Meng, Y., Xin, Z.-H., Jia, X., Liu, X., & Kang, Y. (2025) · Nanoscale · doi:10.1039/d4nr04944f · Cited by 7 · see citing works

Stimuli-responsive gold nanomaterials for theranostics: coordination chemistry, biointerface engineering, and multimodal functionality

Dheyab, M. A., Alsardi, M. M., Abbas, D. N., Tarawneh, M. H., Razzaq, M., Abdullah, W., Alanezi, S. T., Aziz, A. A., & Oladzadabbasabadi, N. (2026) · Coordination Chemistry Reviews · doi:10.1016/j.ccr.2026.218258 · Cited by 7 · see citing works

A computational and experimental investigation of donor-acceptor BODIPY based near-infrared fluorophore for in vivo imaging

Zhang, R., He, X., Jiang, J.-M., Li, P.-P., Wang, H.-Y., Li, L., Yang, J.-X., & Kong, L. (2021) · Bioorganic Chemistry · doi:10.1016/j.bioorg.2021.104789 · Cited by 7 · see citing works

NIR-II Fluorescent Molecular Bottlebrush Prepared by Ring-Opening Polymerization for Programmed Cell Death Ligand-1 Checkpoint Imaging

Wang, C., Sun, P., Fan, Q., & Huang, W. (2021) · ACS Applied Polymer Materials · doi:10.1021/acsapm.1c01216 · Cited by 6 · see citing works

Design, synthesis, and characterization of pH-responsive near infrared bithiophene Aza-BODIPY

Yong, Z., Wen, B., Dou, Q., Guo, H., Hu, C., Bi, J., Zhang, M., Zhao, J., Lin, Y., Wang, J., et al. (2023) · Dyes and Pigments · doi:10.1016/j.dyepig.2023.111614 · Cited by 6 · see citing works

C1 symmetric dual-carboxyl-functionalized BODIPY dye: Synthesis, photophysical properties, and self-assembly behavior via hydrogen bonding

Sun, L., Xiao, Y., Kang, X., Zhu, M., Chang, Y., Zeng, Q., & Xu, H. (2024) · Journal of Molecular Structure · doi:10.1016/j.molstruc.2024.137512 · Cited by 6 · see citing works

NIR-II photo-accelerated polymer nanoparticles boost tumor immunotherapy via PD-L1 silencing and immunogenic cell death

Zhang, T., Tang, D., Wu, P., Jiang, S., Zhang, Y., Naeem, A., Li, Y., Li, C., Hu, B., Guo, S., et al. (2024) · Bioactive Materials · doi:10.1016/j.bioactmat.2024.12.018 · Cited by 10 · see citing works

A NIR‐II Fluorescent PolyBodipy Delivering Cationic Pt‐NHC with Type II Immunogenic Cell Death for Combined Chemotherapy and Photodynamic Immunotherapy

Wang, B., Tang, D., Karges, J., Cui, M., & Xiao, H. (2023) · Advanced Functional Materials · doi:10.1002/adfm.202214824 · Cited by 71 · see citing works

High Singlet Oxygen Yield Photosensitizer Based Polypeptide Nanoparticles for Low-Power Near-Infrared Light Imaging-Guided Photodynamic Therapy

Ruan, Z., Miao, W., Yuan, P., Liu, L., Jiao, L., Hao, E., & Yan, L. (2018) · Bioconjugate Chemistry · doi:10.1021/acs.bioconjchem.8b00576 · Cited by 34 · see citing works

Targeted NIR-responsive theranostic immuno-nanomedicine combined TLR7 agonist with immune checkpoint blockade for effective cancer photothermal immunotherapy

Yasothamani, V., & Vivek, R. (2022) · Journal of Materials Chemistry B · doi:10.1039/d2tb01195f · Cited by 23 · see citing works

NIR II‐Guided Photoactivatable Silencing Polyplex Boosts Cancer Immunotherapy

Zhang, Y., Wang, J., Zhang, T., Tang, D., Yang, H., Guo, S., Fan, Y., Sun, C., Xiao, H., Huang, Y., et al. (2025) · Exploration · doi:10.1002/exp.20240047 · Cited by 21 · see citing works