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Cited by 346

The DOI matches its Crossref record; 85 of the 85 references it cites were found in a registry or an index.

COVID-19 Vaccine Frontrunners and Their Nanotechnology Design

Open access
Chung, Young Hun, Beiss, Veronique, Fiering, Steven N., Steinmetz, Nicole F.·2020·ACS Nano
DOI 10.1021/acsnano.0c07197
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Abstract

Humanity is experiencing a catastrophic pandemic. SARS-CoV-2 has spread globally to cause significant morbidity and mortality, and there still remain unknowns about the biology and pathology of the virus. Even with testing, tracing, and social distancing, many countries are struggling to contain SARS-CoV-2. COVID-19 will only be suppressible when herd immunity develops, either because of an effective vaccine or if the population has been infected and is resistant to reinfection. There is virtually no chance of a return to pre-COVID-19 societal behavior until there is an effective vaccine. Concerted efforts by physicians, academic laboratories, and companies around the world have improved detection and treatment and made promising early steps, developing many vaccine candidates at a pace that has been unmatched for prior diseases. As of August 11, 2020, 28 of these companies have advanced into clinical trials with Moderna, CanSino, the University of Oxford, BioNTech, Sinovac, Sinopharm, Anhui Zhifei Longcom, Inovio, Novavax, Vaxine, Zydus Cadila, Institute of Medical Biology, and the Gamaleya Research Institute having moved beyond their initial safety and immunogenicity studies. This review analyzes these frontrunners in the vaccine development space and delves into their posted results while highlighting the role of the nanotechnologies applied by all the vaccine developers.

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Metadata

Authors
Chung, Y. H., Beiss, V., Fiering, S. N., & Steinmetz, N. F.
Venue
ACS Nano
Publisher
American Chemical Society (ACS)
Published
2020-10-09
Volume
14
Issue
10
Pages
12522-12537
ISSN
  • 1936-0851 (ISSN-L)
  • 1936-086X
DOI
10.1021/acsnano.0c07197
OpenAlex
W3091950240
Cited by
346
References
85
FWCI
9.08
Type
journal article
Language
en
Open access
bronze

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