The DOI matches its Crossref record; 49 of the 49 references it cites were found in a registry or an index.
Terrylenediimide-Based Intrinsic Theranostic Nanomedicines with High Photothermal Conversion Efficiency for Photoacoustic Imaging-Guided Cancer Therapy
Abstract
Activatable theranostic nanomedicines involved in photothermal therapy (PTT) have received constant attention as promising alternatives to traditional therapies in clinic. However, the theranostic nanomedicines widely suffer from instability and complicated nanostructures, which hamper potential clinical applications. Herein, we demonstrated a terrylenediimide (TDI)-poly(acrylic acid) (TPA)-based nanomedicine (TNM) platform used as an intrinsic theranostic agent. As an exploratory paradigm in seeking biomedical applications, TDI was modified with poly(acrylic acid)s (PAAs), resulting in eight-armed, star-like TPAs composed of an outside hydrophilic PAA corona and an inner hydrophobic TDI core. TNMs were readily fabricated via spontaneous self-assembly. Without additional vehicle and cargo, the as-prepared TNMs possessed a robust nanostructure and high photothermal conversion efficiency up to approximately 41%. The intrinsic theranostic properties of TNMs for use in photoacoustic (PA) imaging by a multispectral optoacoustic tomography system and in mediating photoinduced tumor ablation were intensely explored. Our results suggested that the TNMs could be successfully exploited as intrinsic theranostic agents for PA imaging-guided efficient tumor PTT. Thus, these TNMs hold great potential for (pre)clinical translational development.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Cancer Cell Imaging and Photothermal Therapy in the Near-Infrared Region by Using Gold Nanorods
Huang, X., El-Sayed, I. H., Qian, W., & El-Sayed, M. A. (2006) · Journal of the American Chemical Society · doi:10.1021/ja057254a · Cited by 5,436
Photoacoustic tomography: In vivo imaging from organelles to organs
Wang, L. V., & Hu, S. (2012) · Science · doi:10.1126/science.1216210 · Cited by 4,331
Functional Nanomaterials for Phototherapies of Cancer
Cheng, L., Wang, C., Feng, L., Yang, K., & Liu, Z. (2014) · Chemical Reviews · doi:10.1021/cr400532z · Cited by 2,425
Lu, G., Li, S., Guo, Z., Farha, O. K., Hauser, B. G., Qi, X., Wang, Y., Wang, X., Han, S., Liu, X., et al. (2012) · Nature Chemistry · doi:10.1038/nchem.1272 · Cited by 2,148
Microscale Heat Transfer Transduced by Surface Plasmon Resonant Gold Nanoparticles
Roper, D. K., Ahn, W., & Hoepfner, M. (2007) · The Journal of Physical Chemistry C · doi:10.1021/jp064341w · Cited by 1,708
Copper Selenide Nanocrystals for Photothermal Therapy
Hessel, C. M., Pattani, V. P., Rasch, M., Panthani, M. G., Koo, B., Tunnell, J. W., & Korgel, B. A. (2011) · Nano Letters · doi:10.1021/nl201400z · Cited by 1,451
Lovell, J. F., Jin, C. S., Huynh, E., Jin, H., Kim, C., Rubinstein, J. L., Chan, W. C. W., Cao, W., Wang, L. V., & Zheng, G. (2011) · Nature Materials · doi:10.1038/nmat2986 · Cited by 1,362
Imaging and drug delivery using theranostic nanoparticles
Janib, S. M., Moses, A. S., & MacKay, J. A. (2010) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2010.08.004 · Cited by 1,248
Treating metastatic cancer with nanotechnology
Schroeder, A., Heller, D. A., Winslow, M. M., Dahlman, J. E., Pratt, G. W., Langer, R., Jacks, T., & Anderson, D. G. (2012) · Nature Reviews Cancer · doi:10.1038/nrc3180 · Cited by 1,159
Kim, B. Y. S., Rutka, J. T., & Chan, W. C. W. (2010) · New England Journal of Medicine · doi:10.1056/nejmra0912273 · Cited by 1,147
Kirpotin, D. B., Drummond, D. C., Shao, Y., Shalaby, M. R., Hong, K., Nielsen, U. B., Marks, J. D., Benz, C. C., & Park, J. W. (2006) · Cancer Research · doi:10.1158/0008-5472.can-05-4199 · Cited by 1,125
Yin, W., Yan, L., Yu, J., Tian, G., Zhou, L., Zheng, X., Zhang, X., Yong, Y., Li, J., Gu, Z., et al. (2014) · ACS Nano · doi:10.1021/nn501647j · Cited by 923
Lammers, T., Aime, S., Hennink, W. E., Storm, G., & Kiessling, F. (2011) · Accounts of Chemical Research · doi:10.1021/ar200019c · Cited by 870
Huang, K., Ma, H., Liu, J., Huo, S., Kumar, A., Wei, T., Zhang, X., Jin, S., Gan, Y., Wang, P. C., et al. (2012) · ACS Nano · doi:10.1021/nn301282m · Cited by 840
Self-citationHuang, P., Lin, J., Li, W., Rong, P., Wang, Z., Wang, S., Wang, X., Sun, X., Aronova, M., Niu, G., et al. (2013) · Angewandte Chemie International Edition · doi:10.1002/anie.201308986 · Cited by 672
Lin, J., Wang, S., Huang, P., Wang, Z., Chen, S., Niu, G., Li, W., He, J., Cui, D., Lu, G., et al. (2013) · ACS Nano · doi:10.1021/nn4011686 · Cited by 661
Molecular Interactions in Organic Nanoparticles for Phototheranostic Applications
Ng, K. K., & Zheng, G. (2015) · Chemical Reviews · doi:10.1021/acs.chemrev.5b00140 · Cited by 609
Clinical applications of indocyanine green (ICG) enhanced fluorescence in laparoscopic surgery
Boni, L., David, G., Mangano, A., Dionigi, G., Rausei, S., Spampatti, S., Cassinotti, E., & Fingerhut, A. (2015) · Surgical Endoscopy · doi:10.1007/s00464-014-3895-x · Cited by 548
Molecular Imaging with Theranostic Nanoparticles
Jokerst, J. V., & Gambhir, S. S. (2011) · Accounts of Chemical Research · doi:10.1021/ar200106e · Cited by 548
Liang, C., Diao, S., Wang, C., Gong, H., Liu, T., Hong, G., Shi, X., Dai, H., & Liu, Z. (2014) · Advanced Materials · doi:10.1002/adma.201401825 · Cited by 502
Nanoparticles that communicate in vivo to amplify tumour targeting
Park, J., Lin, K., Singh, N., Schwöppe, C., Mesters, R. M., Berdel, W. E., Ruoslahti, E. I., Sailor, M. J., von Maltzhan, G., & Bhatia, S. N. (2010) · DSpace@MIT (Massachusetts Institute of Technology) · Cited by 500
Wang, C., Xu, H., Liang, C., Liu, Y., Li, Z., Yang, G., Cheng, L., Li, Y., & Liu, Z. (2013) · ACS Nano · doi:10.1021/nn4017179 · Cited by 483
Chen, G., Wang, Y., Yang, M., Xu, J., Goh, S. J., Pan, M., & Chen, H. (2010) · Journal of the American Chemical Society · doi:10.1021/ja9090885 · Cited by 412
Xu, M., Zhu, J., Wang, F., Xiong, Y., Wu, Y., Wang, Q., Weng, J., Zhang, Z., Chen, W., & Liu, S. (2016) · ACS Nano · doi:10.1021/acsnano.6b00539 · Cited by 390
Zeng, J., Goldfeld, D., & Xia, Y. (2013) · Angewandte Chemie International Edition · doi:10.1002/anie.201210359 · Cited by 361
Diketopyrrolopyrrole‐Based Semiconducting Polymer Nanoparticles for In Vivo Photoacoustic Imaging
Pu, K., Mei, J., Jokerst, J. V., Hong, G., Antaris, A. L., Chattopadhyay, N., Shuhendler, A. J., Kurosawa, T., Zhou, Y., Gambhir, S. S., et al. (2015) · Advanced Materials · doi:10.1002/adma.201502285 · Cited by 332
Water-soluble perylenediimides: design concepts and biological applications
Sun, M., Müllen, K., & Yin, M. (2016) · Chemical Society Reviews · doi:10.1039/c5cs00754b · Cited by 332
Self-citationYu, J., Javier, D., Yaseen, M. A., Nitin, N., Richards-Kortum, R., Anvari, B., & Wong, M. S. (2010) · Journal of the American Chemical Society · doi:10.1021/ja908139y · Cited by 312
Anticancer Polymeric Nanomedicines
Tong, R., & Cheng, J. (2007) · Polymer Reviews · doi:10.1080/15583720701455079 · Cited by 310
Theranostic Nanoparticles Engineered for Clinic and Pharmaceutics
Ma, X., Zhao, Y., & Liang, X.-J. (2011) · Accounts of Chemical Research · doi:10.1021/ar2000056 · Cited by 297
Self-citationBeyond perylene diimides: synthesis, assembly and function of higher rylene chromophores
Chen, L., Li, C., & Müllen, K. (2014) · J. Mater. Chem. C · doi:10.1039/c3tc32315c · Cited by 291
Self-citationCheng, L., He, W., Gong, H., Wang, C., Chen, Q., Cheng, Z., & Liu, Z. (2013) · Advanced Functional Materials · doi:10.1002/adfm.201301045 · Cited by 277
A targeted approach to cancer imaging and therapy
Li, C. (2014) · Nature Materials · doi:10.1038/nmat3877 · Cited by 268
Self-citationLv, G., Guo, W., Zhang, W., Zhang, T., Li, S., Chen, S., Eltahan, A. S., Wang, D., Wang, Y., Zhang, J., et al. (2016) · ACS Nano · doi:10.1021/acsnano.6b05419 · Cited by 256
Self-citationNanoparticles as Computed Tomography Contrast Agents: Current Status and Future Perspectives
Shilo, M., Reuveni, T., Motiei, M., & Popovtzer, R. (2012) · Nanomedicine · doi:10.2217/nnm.11.190 · Cited by 238
Chen, Q., Wang, C., Zhan, Z., He, W., Cheng, Z., Li, Y., & Liu, Z. (2014) · Biomaterials · doi:10.1016/j.biomaterials.2014.06.013 · Cited by 226
Theranostic nanoparticles for future personalized medicine
Ryu, J. H., Lee, S., Son, S., Kim, S. H., Leary, J. F., Choi, K., & Kwon, I. C. (2014) · Journal of Controlled Release · doi:10.1016/j.jconrel.2014.04.027 · Cited by 222
Biocompatible Conjugated Polymer Nanoparticles for Efficient Photothermal Tumor Therapy
Geng, J., Sun, C., Liu, J., Liao, L., Yuan, Y., Thakor, N., Wang, J., & Liu, B. (2015) · Small · doi:10.1002/smll.201402092 · Cited by 185
Ma, Y.-H., Wu, S.-Y., Wu, T., Chang, Y.-J., Hua, M.-Y., & Chen, J.-P. (2009) · Biomaterials · doi:10.1016/j.biomaterials.2009.02.034 · Cited by 181
Guo, W., Sun, X., Jacobson, O., Yan, X., Min, K., Srivatsan, A., Niu, G., Kiesewetter, D. O., Chang, J., & Chen, X. (2015) · ACS Nano · doi:10.1021/nn505660r · Cited by 166
Self-citationChen, D., Wang, C., Nie, X., Li, S., Li, R., Guan, M., Liu, Z., Chen, C., Wang, C., Shu, C., et al. (2014) · Advanced Functional Materials · doi:10.1002/adfm.201401560 · Cited by 155
Indocyanine green (ICG) and laser irradiation induce photooxidation
Abels, C., Fickweiler, S., Weiderer, P., Bäumler, W., Hofstädter, F., Landthaler, M., & Szeimies, R. (2000) · Archives of Dermatological Research · doi:10.1007/s004030000147 · Cited by 137
Song, X., Gong, H., Liu, T., Cheng, L., Wang, C., Sun, X., Liang, C., & Liu, Z. (2014) · Small · doi:10.1002/smll.201401025 · Cited by 114
Wang, H., Wu, Y. F., Zhao, R., & Nie, G. (2013) · Advanced Materials · doi:10.1002/adma.201204750 · Cited by 102
A Fluorescent Core−Shell Dendritic Macromolecule Specifically Stains The Extracellular Matrix
Yin, M., Shen, J., Pflugfelder, G. O., & Müllen, K. (2008) · Journal of the American Chemical Society · doi:10.1021/ja8022362 · Cited by 101
Self-citationLiu, Y., Yang, K., Cheng, L., Zhu, J., Ma, X., Xu, H., Li, Y., Guo, L., Gu, H., & Liu, Z. (2013) · Nanomedicine Nanotechnology Biology and Medicine · doi:10.1016/j.nano.2013.02.010 · Cited by 85
Yang, Z., You, S., Ji, C., Yin, M., Yang, W., & Shen, J. (2015) · Advanced Materials · doi:10.1002/adma.201504993 · Cited by 80
Self-citationGuo, W., Yang, W., Wang, Y., Sun, X., Liu, Z., Zhang, B., Chang, J. K., & Chen, X. S. (2014) · Nano Research · doi:10.1007/s12274-014-0518-8 · Cited by 73
Self-citationAn innovative pre-targeting strategy for tumor cell specific imaging and therapy
Qin, S., Peng, M., Rong, L., Jia, H.-Z., Chen, S., Cheng, S., Feng, J. X., & Zhang, X. (2015) · Nanoscale · doi:10.1039/c5nr03862f · Cited by 31
Cited by
Recent Strategies to Develop Innovative Photosensitizers for Enhanced Photodynamic Therapy
Pham, T. C., Nguyen, V.-N., Choi, Y., Lee, S., & Yoon, J. (2021) · Chemical Reviews · doi:10.1021/acs.chemrev.1c00381 · Cited by 1,813
Zhou, J., Li, M., Hou, Y., Luo, Z., Chen, Q., Cao, H., Huo, R., Xue, C., Sutrisno, L., Hao, L., et al. (2018) · ACS Nano · doi:10.1021/acsnano.8b00309 · Cited by 424
Nanoagent‐Promoted Mild‐Temperature Photothermal Therapy for Cancer Treatment
Gao, G., Sun, X., & Liang, G. (2021) · Advanced Functional Materials · doi:10.1002/adfm.202100738 · Cited by 359
NIR-II bioimaging of small organic molecule
Su, Y., Yu, B., Wang, S., Cong, H., & Shen, Y. (2021) · Biomaterials · doi:10.1016/j.biomaterials.2021.120717 · Cited by 251
Dai, Y., Sun, Z., Zhao, H., Qi, D., Li, X., Gao, D., Li, M., Fan, Q., Shen, Q., & Huang, W. (2021) · Biomaterials · doi:10.1016/j.biomaterials.2021.120935 · Cited by 117
Metadata
- Authors
- Zhang, S., Guo, W., Wei, J., Li, C., Liang, X.-J., & Yin, M.
- Venue
- ACS Nano
- Publisher
- American Chemical Society (ACS)
- Published
- 2017-03-21
- Volume
- 11
- Issue
- 4
- Pages
- 3797-3805
- ISSN
- 1936-0851 (ISSN-L)
- 1936-086X
- OpenAlex
- W2596583190
- Cited by
- 284
- References
- 49
- FWCI
- 16.18
- Type
- journal article
- Language
- en
- Open access
- closed
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
