The DOI matches its Crossref record; 41 of the 41 references it cites were found in a registry or an index.
Selective Detection of Acetone and Hydrogen Sulfide for the Diagnosis of Diabetes and Halitosis Using SnO2 Nanofibers Functionalized with Reduced Graphene Oxide Nanosheets
Abstract
Sensitive detection of acetone and hydrogen sulfide levels in exhaled human breath, serving as breath markers for some diseases such as diabetes and halitosis, may offer useful information for early diagnosis of these diseases. Exhaled breath analyzers using semiconductor metal oxide (SMO) gas sensors have attracted much attention because they offer low cost fabrication, miniaturization, and integration into portable devices for noninvasive medical diagnosis. However, SMO gas sensors often display cross sensitivity to interfering species. Therefore, selective real-time detection of specific disease markers is a major challenge that must be overcome to ensure reliable breath analysis. In this work, we report on highly sensitive and selective acetone and hydrogen sulfide detection achieved by sensitizing electrospun SnO2 nanofibers with reduced graphene oxide (RGO) nanosheets. SnO2 nanofibers mixed with a small amount (0.01 wt %) of RGO nanosheets exhibited sensitive response to hydrogen sulfide (Rair/Rgas = 34 at 5 ppm) at 200 °C, whereas sensitive acetone detection (Rair/Rgas = 10 at 5 ppm) was achieved by increasing the RGO loading to 5 wt % and raising the operation temperature to 350 °C. The detection limit of these sensors is predicted to be as low as 1 ppm for hydrogen sulfide and 100 ppb for acetone, respectively. These concentrations are much lower than in the exhaled breath of healthy people. This demonstrates that optimization of the RGO loading and the operation temperature of RGO-SnO2 nanocomposite gas sensors enables highly sensitive and selective detection of breath markers for the diagnosis of diabetes and halitosis.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Preparation of Graphitic Oxide
Hummers, W. S., & Offeman, R. E. (1958) · Journal of the American Chemical Society · doi:10.1021/ja01539a017 · Cited by 29,920
Synthesis of graphene-based nanosheets via chemical reduction of exfoliated graphite oxide
Stankovich, S., Dikin, D. A., Piner, R. D., Kohlhaas, K. A., Kleinhammes, A., Jia, Y., Wu, Y., Nguyen, S. T., & Ruoff, R. S. (2007) · Carbon · doi:10.1016/j.carbon.2007.02.034 · Cited by 13,878
Studying disorder in graphite-based systems by Raman spectroscopy
Pimenta, M. A., Dresselhaus, G., Dresselhaus, M. S., Cançado, L. G., Jorio, A., & Saito, R. (2007) · Phys. Chem. Chem. Phys. · doi:10.1039/b613962k · Cited by 4,623
Yang, D., Velamakanni, A., Bozoklu, G., Park, S., Stoller, M., Piner, R. D., Stankovich, S., Jung, I., Field, D. A., Ventrice, C. A., et al. (2009) · Carbon · doi:10.1016/j.carbon.2008.09.045 · Cited by 3,260
Reduced graphene oxide by chemical graphitization
Moon, I. K., Lee, J., Ruoff, R. S., & Lee, H. (2010) · Nature Communications · doi:10.1038/ncomms1067 · Cited by 2,135
Oxide Semiconductor Gas Sensors
Yamazoe, N., Sakai, G., & Shimanoe, K. (2003) · Catalysis Surveys from Asia · doi:10.1023/a:1023436725457 · Cited by 1,291
Diagnosing lung cancer in exhaled breath using gold nanoparticles
Peng, G., Tisch, U., Adams, O., Hakim, M., Shehada, N., Broza, Y. Y., Billan, S., Abdah-Bortnyak, R., Kuten, A., & Haick, H. (2009) · Nature Nanotechnology · doi:10.1038/nnano.2009.235 · Cited by 1,263
Hontoria-Lucas, C., López-Peinado, A. J., López-González, J. D. D., Rojas-Cervantes, M. L., & Martín-Aranda, R. M. (1995) · Carbon · doi:10.1016/0008-6223(95)00120-3 · Cited by 1,079
Evidence of Graphitic AB Stacking Order of Graphite Oxides
Jeong, H.-K., Lee, Y. P., Lahaye, R. J. W. E., Park, M.-H., An, K. H., Kim, I. J., Yang, C.-W., Park, C. Y., Ruoff, R. S., & Lee, Y. H. (2008) · Journal of the American Chemical Society · doi:10.1021/ja076473o · Cited by 1,078
Self-citationLightcap, I. V., Kosel, T. H., & Kamat, P. V. (2010) · Nano Letters · doi:10.1021/nl9035109 · Cited by 1,044
All‐Organic Vapor Sensor Using Inkjet‐Printed Reduced Graphene Oxide
Dua, V., Surwade, S. P., Ammu, S., Agnihotra, S. R., Jain, S., Roberts, K. E., Park, S., Ruoff, R. S., & Manohar, S. K. (2010) · Angewandte Chemie International Edition · doi:10.1002/anie.200905089 · Cited by 932
Devan, R. S., Patil, R. A., Lin, J., & Ma, Y. (2012) · Advanced Functional Materials · doi:10.1002/adfm.201201008 · Cited by 813
Reduced Graphene Oxide Conjugated Cu2O Nanowire Mesocrystals for High-Performance NO2 Gas Sensor
Deng, S., Tjoa, V., Fan, H. M., Tan, H. R., Sayle, D. C., Olivo, M., Mhaisalkar, S., Wei, J., & Sow, C. H. (2012) · Journal of the American Chemical Society · doi:10.1021/ja211683m · Cited by 757
Metal oxide nano-crystals for gas sensing
Comini, E. (2006) · Analytica Chimica Acta · doi:10.1016/j.aca.2005.10.069 · Cited by 717
Righettoni, M., Tricoli, A., & Pratsinis, S. E. (2010) · Analytical Chemistry · doi:10.1021/ac902695n · Cited by 630
Metal oxide nanocrystals for gas sensing
Faglia, G., Baratto, C., Comini, E., Sberveglieri, G., Zha, M., & Zappettini, A. (2006) · Proceedings of IEEE Sensors, 2004. · doi:10.1109/icsens.2004.1426130 · Cited by 603
Detection of Lung Cancer by Sensor Array Analyses of Exhaled Breath
Machado, R. F., Laskowski, D., Deffenderfer, O., Burch, T., Zheng, S., Mazzone, P. J., Mekhail, T., Jennings, C., Stoller, J. K., Pyle, J., et al. (2005) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.200409-1184oc · Cited by 602
Morrison, S. R. (1981) · Sensors and Actuators · doi:10.1016/0250-6874(81)80054-6 · Cited by 538
Temperature modulation in semiconductor gas sensing
Lee, A. (1999) · Sensors and Actuators B Chemical · doi:10.1016/s0925-4005(99)00241-5 · Cited by 487
Kim, H.-R., Haensch, A., Kim, I., Bârsan, N., Weimar, U., & Lee, J. (2011) · Advanced Functional Materials · doi:10.1002/adfm.201101154 · Cited by 419
Self-citationYang, D., Kamienchick, I., Youn, D. Y., Rothschild, A., & Kim, I. (2010) · Advanced Functional Materials · doi:10.1002/adfm.201001251 · Cited by 404
Self-citationShin, J., Choi, S., Lee, I., Youn, D., Park, C. O., Lee, J., Tuller, H. L., & Kim, I. (2013) · Advanced Functional Materials · doi:10.1002/adfm.201202729 · Cited by 391
Self-citationHow Do the Electrical Properties of Graphene Change with its Functionalization?
Sreeprasad, T. S., & Berry, V. (2013) · Small · doi:10.1002/smll.201202196 · Cited by 386
Correlation of breath ammonia with blood urea nitrogen and creatinine during hemodialysis
Narasimhan, L. R., Goodman, W., & Patel, C. K. N. (2001) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.071057598 · Cited by 379
Preparation of graphene by a low-temperature thermal reduction at atmosphere pressure
Chen, W., & Yan, L. (2010) · Nanoscale · doi:10.1039/b9nr00191c · Cited by 367
Advances and new directions in gas-sensing devices
Kim, I.-D., Rothschild, A., & Tuller, H. L. (2013) · Acta Materialia · doi:10.1016/j.actamat.2012.10.041 · Cited by 343
Self-citationChoi, S.-J., Lee, I., Jang, B.-H., Youn, D.-Y., Ryu, W.-H., Park, C. O., & Kim, I.-D. (2013) · Analytical Chemistry · doi:10.1021/ac303148a · Cited by 311
Self-citationHighly selective gas sensor arrays based on thermally reduced graphene oxide
Lipatov, A., Varezhnikov, A., Wilson, P., Sysoev, V., Kolmakov, A., & Sinitskii, A. (2013) · Nanoscale · doi:10.1039/c3nr00747b · Cited by 307
Russo, P. A., Donato, N., Leonardi, S. G., Baek, S., Conte, D. E., Neri, G., & Pinna, N. (2012) · Angewandte Chemie International Edition · doi:10.1002/anie.201204373 · Cited by 282
ZnO Nanotetrapods: Controlled Vapor‐Phase Synthesis and Application for Humidity Sensing
Qiu, Y., & Yang, S. (2007) · Advanced Functional Materials · doi:10.1002/adfm.200601128 · Cited by 237
Lin, Q., Li, Y., & Yang, M. (2012) · Sensors and Actuators B: Chemical · doi:10.1016/j.snb.2012.06.055 · Cited by 234
Zhou, L., Shen, F., Tian, X., Wang, D., Zhang, T., & Chen, W. (2013) · Nanoscale · doi:10.1039/c2nr33164k · Cited by 198
Extra-oral halitosis: an overview
Tangerman, A., & Winkel, E. G. (2010) · Journal of Breath Research · doi:10.1088/1752-7155/4/1/017003 · Cited by 191
Exhaled Carbon Monoxide and Nitric Oxide in COPD
Montuschi, P., Kharitonov, S. A., & Barnes, P. J. (2001) · Chest · doi:10.1378/chest.120.2.496 · Cited by 178
Fleischer, M., Simon, E., Rumpel, E., Ulmer, H., Harbeck, M., Wandel, M., Fietzek, C., Weimar, U., & Meixner, H. (2002) · Sensors and Actuators B: Chemical · doi:10.1016/s0925-4005(01)01056-5 · Cited by 169
Exhaled Pentane Levels in Acute Asthma
Olopade, C. O., Zakkar, M., Swedler, W. I., & Rubinstein, I. (1997) · Chest · doi:10.1378/chest.111.4.862 · Cited by 162
Singh, N., Gupta, R. K., & Lee, P. S. (2011) · ACS Applied Materials & Interfaces · doi:10.1021/am101259t · Cited by 158
High breath pentane concentrations during acute myocardial infarction
Weitz, Z., Birnbaum, A. J., Skosey, J. L., Sobotka, P. A., & Zarling, E. J. (1991) · The Lancet · doi:10.1016/0140-6736(91)91569-g · Cited by 128
Ma, J., Mei, L., Chen, Y., Li, Q., Wang, T., Xu, Z. Q., Duan, X., & Zheng, W. (2012) · Nanoscale · doi:10.1039/c2nr33201a · Cited by 113
Zai, J., Zhu, J., Qi, R., & Qian, X. (2012) · Journal of Materials Chemistry A · doi:10.1039/c2ta00750a · Cited by 80
Plasma vitamin E and selenium and breath pentane in home parenteral nutrition patients
Lemoyne, M., Gossum, A. V., Kurian, R., & Jeejeebhoy, K. N. (1988) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/48.5.1310 · Cited by 70
Cited by
Recent advances in graphene based gas sensors
Varghese, S. S., Lonkar, S., Singh, K. K., Swaminathan, S., & Abdala, A. (2015) · Sensors and Actuators B: Chemical · doi:10.1016/j.snb.2015.04.062 · Cited by 890
Room Temperature Gas Sensing of Two-Dimensional Titanium Carbide (MXene)
Lee, E., VahidMohammadi, A., Prorok, B. C., Yoon, Y. S., Beidaghi, M., & Kim, D.-J. (2017) · ACS Applied Materials & Interfaces · doi:10.1021/acsami.7b11055 · Cited by 878
Electrically-Transduced Chemical Sensors Based on Two-Dimensional Nanomaterials
Meng, Z., Stolz, R. M., Mendecki, L., & Mirica, K. A. (2019) · Chemical Reviews · doi:10.1021/acs.chemrev.8b00311 · Cited by 773
A Review on Graphene-Based Gas/Vapor Sensors with Unique Properties and Potential Applications
Wang, T., Huang, D., Yang, Z., Xu, S., He, G., Li, X., Hu, N., Yin, G., He, D., & Zhang, L. (2016) · Nano-Micro Letters · doi:10.1007/s40820-015-0073-1 · Cited by 600
Song, Z., Wei, Z., Wang, B., Luo, Z., Xu, S., Zhang, W., Yu, H., Li, M., Huang, Z., Zang, J., et al. (2016) · Chemistry of Materials · doi:10.1021/acs.chemmater.5b04850 · Cited by 438
Metadata
- Authors
- Choi, S.-J., Jang, B.-H., Lee, S.-J., Min, B. K., Rothschild, A., & Kim, I.-D.
- Venue
- ACS Applied Materials & Interfaces
- Publisher
- American Chemical Society (ACS)
- Published
- 2014-02-05
- Volume
- 6
- Issue
- 4
- Pages
- 2588-2597
- ISSN
- 1944-8244 (ISSN-L)
- 1944-8252
- OpenAlex
- W2079094579
- Cited by
- 393
- References
- 41
- FWCI
- 19.10
- Type
- journal article
- Language
- en
- Open access
- closed
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
