The DOI matches its Crossref record; 34 of the 34 references it cites were found in a registry or an index.
A Fluorescent Intercalator Displacement Assay for Establishing DNA Binding Selectivity and Affinity
Abstract
A summary of the qualitative and quantitative elements of a fluorescent intercalator displacement (FID) assay useful for establishing the DNA binding selectivity, affinity, stoichiometry, and binding site size and distinguishing modes of DNA binding is provided.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
THE ATTRACTIONS OF PROTEINS FOR SMALL MOLECULES AND IONS
Scatchard, G. (1949) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.1949.tb27297.x · Cited by 19,778
A fluorescent complex between ethidium bromide and nucleic acids
Pecq, J. B. L., & Paoletti, C. (1967) · Journal of Molecular Biology · doi:10.1016/0022-2836(67)90353-1 · Cited by 2,393
DNAase footprinting a simple method for the detection of protein-DNA binding specificity
Galas, D. J., & Schmitz, A. (1978) · Nucleic Acids Research · doi:10.1093/nar/5.9.3157 · Cited by 2,056
Transition from Moderate to Excessive Drug Intake: Change in Hedonic Set Point
Ahmed, S. H., & Koob, G. F. (1998) · Science · doi:10.1126/science.282.5387.298 · Cited by 1,154
Molecular recognition of DNA by small molecules
Dervan, P. (2001) · Bioorganic & Medicinal Chemistry · doi:10.1016/s0968-0896(01)00262-0 · Cited by 902
Design of Sequence-Specific DNA-Binding Molecules
Dervan, P. B. (1986) · Science · doi:10.1126/science.2421408 · Cited by 838
HMG domain proteins: architectural elements in the assembly of nucleoprotein structures
Grosschedl, R., Giese, K., & Pagel, J. (1994) · Trends in Genetics · doi:10.1016/0168-9525(94)90232-1 · Cited by 813
Travis, A., Amsterdam, A., Belanger, C., & Grosschedl, R. (1991) · Genes & Development · doi:10.1101/gad.5.5.880 · Cited by 614
DNA Cross-Linking Agents as Antitumor Drugs
Rajski, S. R., & Williams, R. M. (1998) · Chemical Reviews · doi:10.1021/cr9800199 · Cited by 592
Regulation of LEF-1/TCF transcription factors by Wnt and other signals
Eastman, Q., & Grosschedl, R. (1999) · Current Opinion in Cell Biology · doi:10.1016/s0955-0674(99)80031-3 · Cited by 540
van de Wetering, M., Oosterwegel, M., Dooijes, D., & Clevers, H. (1991) · The EMBO Journal · doi:10.1002/j.1460-2075.1991.tb07928.x · Cited by 538
Regulation of gene expression by small molecules
Gottesfeld, J. M., Neely, L., Trauger, J. W., Baird, E. E., & Dervan, P. B. (1997) · Nature · doi:10.1038/387202a0 · Cited by 470
The interactions between the fluorescent dye thiazole orange and DNA
Nygren, J., Svanvik, N., & Kubista, M. (1998) · Biopolymers · doi:10.1002/(sici)1097-0282(199807)46:1<39::aid-bip4>3.0.co;2-z · Cited by 452
Controlling Gene Expression in Living Cells Through Small Molecule-RNA Interactions
Werstuck, G., & Green, M. R. (1998) · Science · doi:10.1126/science.282.5387.296 · Cited by 422
Recognition of DNA by designed ligands at subnanomolar concentrations
Trauger, J. W., Baird, E. E., & Dervan, P. B. (1996) · Nature · doi:10.1038/382559a0 · Cited by 397
Waterman, M. L., Fischer, W. H., & Jones, K. A. (1991) · Genes & Development · doi:10.1101/gad.5.4.656 · Cited by 359
Van Dyke, M. W., Hertzberg, R. P., & Dervan, P. B. (1982) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.79.18.5470 · Cited by 328
CC‐1065 and the Duocarmycins: Understanding their Biological Function through Mechanistic Studies
Boger, D. L., & Johnson, D. S. (1996) · Angewandte Chemie International Edition in English · doi:10.1002/anie.199614381 · Cited by 319
Self-citationIn vivo repression by a site-specific DNA-binding protein designed against an oncogenic sequence
Choo, Y., Sánchez-García, I., & Klug, A. (1994) · Nature · doi:10.1038/372642a0 · Cited by 292
DNA-binding properties of the HMG domain of the lymphoid-specific transcriptional regulator LEF-1.
Giese, K., Amsterdam, A., & Grosschedl, R. (1991) · Genes & Development · doi:10.1101/gad.5.12b.2567 · Cited by 265
Antisense Properties of Duplex- and Triplex-Forming PNAs
Knudsen, H., & Nielsen, P. E. (1996) · Nucleic Acids Research · doi:10.1093/nar/24.3.494 · Cited by 256
Mechanisms for selecting 5′ splice sites in mammalian pre-mRNA splicing
Horowitz, D. S., & Krainer, A. R. (1994) · Trends in Genetics · doi:10.1016/0168-9525(94)90233-x · Cited by 256
Thiesen, H.-J., & Bach, C. (1990) · Nucleic Acids Research · doi:10.1093/nar/18.11.3203 · Cited by 225
Mrksich, M., Wade, W. S., Dwyer, T. J., Geierstanger, B. H., Wemmer, D. E., & Dervan, P. B. (1992) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.89.16.7586 · Cited by 184
Bioorganic chemistry : nucleic acids
Hecht, S. M. (1996) · Oxford University Press eBooks · Cited by 173
McLaughlin, L. W., Benseler, F., Graeser, E., Piel, N., & Scholtissek, S. (1987) · Biochemistry · doi:10.1021/bi00397a007 · Cited by 168
Taylor, J., Schultz, P. G., & Dervan, P. B. (1984) · Tetrahedron · doi:10.1016/0040-4020(84)85050-4 · Cited by 152
Royer‐Pokora, B., Gordon, L. K., & Haseltine, W. A. (1981) · Nucleic Acids Research · doi:10.1093/nar/9.18.4595 · Cited by 144
What causes aqueous acceleration of the Claisen rearrangement?
Cramer, C. J., & Truhlar, D. G. (1992) · Journal of the American Chemical Society · doi:10.1021/ja00049a007 · Cited by 92
Influence of a Terminal Formamido Group on the Sequence Recognition of DNA by Polyamides
Lacy, E. R., Le, N. M., Price, C. A., Lee, M., & Wilson, W. D. (2002) · Journal of the American Chemical Society · doi:10.1021/ja016154b · Cited by 79
Chiang, S.-Y., Azizkhan, J. C., & Beerman, T. A. (1998) · Biochemistry · doi:10.1021/bi9721142 · Cited by 56
Altered sequence specificity identified from a library of DNA-binding small molecules
Guelev, V. M., Harting, M. T., Lokey, R. S., & Iverson, B. L. (2000) · Chemistry & Biology · doi:10.1016/s1074-5521(00)00007-x · Cited by 33
Hayashibara, K. C., & Verdine, G. L. (1992) · Biochemistry · doi:10.1021/bi00161a002 · Cited by 18
A whole blood facscan assay to look at cytokine production by NK cells in cancer patients.
Mendes, R. L., Bromelow, K. V., Westby, M., Galea‐Lauri, J., Smith, I. E., Mer., O., & Souberbielle, B. E. (1999) · British Journal of Cancer · Cited by 15
Cited by
Luminescent sensors and switches in the early 21st century
Callan, J. F., de Silva, A. P., & Magri, D. C. (2005) · Tetrahedron · doi:10.1016/j.tet.2005.05.043 · Cited by 1,123
Nguyen, B. T., & Anslyn, E. V. (2006) · Coordination Chemistry Reviews · doi:10.1016/j.ccr.2006.04.009 · Cited by 668
A Targeting Modality for Destruction of RNA Polymerase I that Possesses Anticancer Activity
Peltonen, K., Colis, L., Liu, H., Trivedi, R., Moubarek, M. S., Moore, H. M., Bai, B., Rudek, M. A., Bieberich, C. J., & Laiho, M. (2014) · Cancer Cell · doi:10.1016/j.ccr.2013.12.009 · Cited by 314
Small-molecule activation of OGG1 increases oxidative DNA damage repair by gaining a new function
Michel, M., Benítez-Buelga, C., Calvo, P. A., Hanna, B. M. F., Mortusewicz, O., Masuyer, G., Davies, J., Wallner, O., Sanjiv, K., Albers, J. J., et al. (2022) · Science · doi:10.1126/science.abf8980 · Cited by 90
Uncovering an allosteric mode of action for a selective inhibitor of human Bloom syndrome protein
Chen, X., Ali, Y. I., Fisher, C. E., Arribas-Bosacoma, R., Rajasekaran, M. B., Williams, G., Walker, S., Booth, J. R., Hudson, J. J., Roe, S. M., et al. (2021) · eLife · doi:10.7554/elife.65339 · Cited by 34
Metadata
- Authors
- Tse, W. C., & Boger, D. L.
- Venue
- Accounts of Chemical Research
- Publisher
- American Chemical Society (ACS)
- Published
- 2003-11-18
- Volume
- 37
- Issue
- 1
- Pages
- 61-69
- ISSN
- 0001-4842 (ISSN-L)
- 1520-4898
- OpenAlex
- W2144208378
- Cited by
- 288
- References
- 34
- FWCI
- 3.11
- Type
- journal article
- Language
- en
- Open access
- closed
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
