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Synthesis and Applications of Biomedical and Pharmaceutical Polymers via Click Chemistry Methodologies
Abstract
In this review, the synthesis and application of biomedical and pharmaceutical polymers synthesized via the copper(I)-catalyzed alkyne-azide cycloaddition, the thiol-ene reaction, or a combination of both click reactions are discussed. Since the introduction of both "click" methods, numerous articles have disclosed new approaches for the synthesis of polymers with different architectures, e.g., block and graft copolymers, dendrimers, and hydrogels, for pharmaceutical and biomedical applications. By describing selected examples, an overview is given of the possibilities and limitations that these two "click" methods may offer.
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Metadata
- Authors
- van Dijk, M., Rijkers, D. T. S., Liskamp, R. M. J., van Nostrum, C. F., & Hennink, W. E.
- Venue
- Bioconjugate Chemistry
- Publisher
- American Chemical Society (ACS)
- Published
- 2009-07-17
- Volume
- 20
- Issue
- 11
- Pages
- 2001-2016
- ISSN
- 1043-1802 (ISSN-L)
- 1520-4812
- OpenAlex
- W2075511023
- Cited by
- 300
- References
- 121
- FWCI
- 18.84
- Type
- journal article
- Language
- en
- Open access
- closed
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
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Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.