Supercritical carbon dioxide extraction of fucoxanthin from Undaria pinnatifida
Abstract
Undaria pinnatifida, commonly known as wakame in Japan, is one species of brown seaweeds containing valuable bioactive organic compounds such as fucoxanthin, a carotenoid, which has numerous functional properties. However, most of the seaweeds that do not meet strict quality standards are normally discarded as wastes or returned to the sea, a situation which is becoming an environmental concern. In this research, supercritical carbon dioxide (SCCO₂) extraction was investigated for the isolation of fucoxanthin. SCCO₂ extraction experiments were carried out at temperature range of 25-60 °C and pressure range of 20-40 MPa, at a carbon dioxide flow rate of 1.0-4.0 mL/min. Results showed that fucoxanthin recovery closed to 80% could be obtained at 40 °C and 40 MPa in extraction time of 180 min. The recovery increased with decreasing temperature and increasing pressure. Pretreatment with microwave (MW) also enhanced the efficiency of extraction due most likely to disruption of the cell membrane. Application of SCCO₂, generally regarded as safe and environmentally benign solvent, for extraction of useful bioactive compounds from unwanted or substandard seaweeds look promising in the near future. The extracts obtained using the method can be utilized as food and pharmaceutical additive, and can be used in the development of new health supplements.
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Quitain et al. showed highest yield of fucoxanthin at 40 MPa and 40 °C, and with increase of temperature yield decreased due to degradation and decreased solubility in SC-CO2.
“Quitain et al. [42] showed that the highest yield of fucoxanthin was obtained at a pressure of 40 MPa and temperature of 40 °C, and with the increase of temperature the yield of fucoxanthin decreased due to the degradation of fucoxanthin and decreased solubility in SC-CO2.”
From Overview on the Application of Modern Methods for the Extraction of Bioactive Compounds from Marine Macroalgae (2018) · cites this paper as [42]
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- Authors
- Quitain, A. T., Kai, T., Sasaki, M., & Goto, M.
- Affiliations
- Kumamoto University (JP)
- Nagoya University (JP)
- Corresponding author
- Quitain, Armando T.
- Venue
- Journal of Agricultural and Food Chemistry
- Publisher
- American Chemical Society (ACS)
- Published
- 2013-06-06
- Volume
- 61
- Issue
- 24
- Pages
- 5792-5797
- ISSN
- 0021-8561 (ISSN-L)
- 1520-5118
- OpenAlex
- W2314231510
- Cited by
- 96
- References
- 29
- Citations by year
- 2026: 10 · 2025: 10 · 2024: 6 · 2023: 4 · 2022: 9 · 2021: 18 · 2020: 8 · 2019: 5 · 2018: 6 · 2017: 8 · 2016: 5 · 2015: 4 · 2014: 2 · 2013: 1
- FWCI
- 6.11
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of Agricultural and Food Chemistry (publishedVersion)
- PubMed (publishedVersion)
- Helmholtz Centre for Ocean Research Kiel (GEOMAR) (acceptedVersion)
- Topics
- Life Sciences › Agricultural and Biological Sciences › Aquatic Science › Seaweed-derived Bioactive Compounds
- Physical Sciences › Engineering › Biomedical Engineering › Phase Equilibria and Thermodynamics
- Physical Sciences › Energy › Renewable Energy, Sustainability and the Environment › Algal biology and biofuel production
- Keywords
- fucoxanthin, Undaria pinnatifida, supercritical CO2 extraction, carotenoids, brown algae, microwave pretreatment, extraction pressure and temperature, seaweed waste valorization, bioactive compounds
- MeSH terms
- Antioxidants, Carbon Dioxide, Food-Processing Industry, Industrial Waste, Japan, Pacific Ocean, Seaweed, Dietary Supplements, Xanthophylls, Chromatography, Supercritical Fluid, Undaria
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