The DOI matches its Crossref record; 31 of the 31 references it cites were found in a registry or an index.
Bioprocessing of Wheat Bran Improves in vitro Bioaccessibility and Colonic Metabolism of Phenolic Compounds
Abstract
Ferulic acid (FA) is the most abundant phenolic compound in wheat grain, mainly located in the bran. However, its bioaccessibility from the bran matrix is extremely low. Different bioprocessing techniques involving fermentation or enzymatic and fermentation treatments of wheat bran were developed aiming at improving the bioaccessibility of phenolic compounds in bran-containing breads. The bioaccessibility of ferulic acid, p-coumaric acid, and sinapic acid was assessed with an in vitro model of upper gastrointestinal tract (TIM-1). Colonic metabolism of the phenolic compounds in the nonbioaccessible fraction of the breads was studied with an in vitro model of human colon (TIM-2). The most effective treatment was the combination of enzymes and fermentation that increased the bioaccessibility of FA from 1.1% to 5.5%. The major colonic metabolites were 3-(3-hydroxyphenyl)propionic acid and 3-phenylpropionic acid. Bran bioprocessing increases the bioaccessibility of phenolic compounds as well as the colonic end metabolite 3-phenylpropionic acid.
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Cites
Polyphenols: Food sources and bioavailability
Manach, C., Scalbert, A., Morand, C., Rémésy, C., & Jiménez, L. (2004) · The American Journal of Clinical Nutrition · doi:10.1093/ajcn/79.5.727 · Cited by 8,175
Measurement of cellulase activities
Ghose, T. K. (1987) · Pure and Applied Chemistry · doi:10.1351/pac198759020257 · Cited by 6,174
Interlaboratory testing of methods for assay of xylanase activity
Bailey, M. J., Biely, P., & Poutanen, K. (1992) · Journal of Biotechnology · doi:10.1016/0168-1656(92)90074-j · Cited by 2,449
Self-citationFerulic Acid: Therapeutic Potential Through Its Antioxidant Property
Srinivasan, M., Sudheer, A. R., & Menon, V. P. (2007) · Journal of Clinical Biochemistry and Nutrition · doi:10.3164/jcbn.40.92 · Cited by 1,075
A Multicompartmental Dynamic Computer-controlled Model Simulating the Stomach and Small Intestine
Minekus, M., Marteau, P., Havenaar, R., & Veld, J. H. J. H. I. (1995) · Alternatives to Laboratory Animals · doi:10.1177/026119299502300205 · Cited by 684
Self-citationSlavin, J. (2004) · Nutrition Research Reviews · doi:10.1079/nrr200374 · Cited by 610
Mattila, P., Pihlava, J.-M., & Hellström, J. (2005) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf051437z · Cited by 567
Colonic metabolism of dietary polyphenols: influence of structure on microbial fermentation products
Rechner, A. R., Smith, M. A., Kuhnle, G., Gibson, G. R., Debnam, E. S., Srai, S. K. S., Moore, K. P., & Rice-Evans, C. A. (2004) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2003.09.022 · Cited by 511
Déprez, S., Mila, I., Lapierre, C., Brezillon, C., Rabot, S., Philippe, C., & Scalbert, A. (2000) · The Journal of Nutrition · doi:10.1093/jn/130.11.2733 · Cited by 494
The metabolic fate of dietary polyphenols in humans
Rechner, A. R., Kuhnle, G., Bremner, P., Hubbard, G. P., Moore, K. P., & Rice-Evans, C. A. (2002) · Free Radical Biology and Medicine · doi:10.1016/s0891-5849(02)00877-8 · Cited by 475
In vitro metabolism of anthocyanins by human gut microflora
Aura, A.-M., Martin-Lopez, P., O’Leary, K. A., Williamson, G., Oksman-Caldentey, K.-M., Poutanen, K., & Santos-Buelga, C. (2005) · European Journal of Nutrition · doi:10.1007/s00394-004-0502-2 · Cited by 459
Self-citationMinekus, M., Smeets-Peeters, M., Bernalier, A., Marol-Bonnin, S., Havenaar, R., Marteau, P., Alric, M., Fonty, G., & Huis in't Veld, J. H. J. (1999) · Applied Microbiology and Biotechnology · doi:10.1007/s002530051622 · Cited by 458
Self-citationDietary Intake and Major Food Sources of Polyphenols in Finnish Adults3
Ovaskainen, M.-L., Törrönen, R., Koponen, J. M., Sinkko, H., Hellström, J., Reinivuo, H., & Mattila, P. (2008) · The Journal of Nutrition · doi:10.1093/jn/138.3.562 · Cited by 434
Quantitative Measurement of Total Starch in Cereal Flours and Products
McCleary, B. V., Solah, V., & Gibson, T. S. (1994) · Journal of Cereal Science · doi:10.1006/jcrs.1994.1044 · Cited by 376
Dry processes to develop wheat fractions and products with enhanced nutritional quality
Hemery, Y., Rouau, X., Lullien-Pellerin, V., Barron, C., & Abecassis, J. (2007) · Journal of Cereal Science · doi:10.1016/j.jcs.2007.09.008 · Cited by 343
Diferulates as structural components in soluble and insoluble cereal dietary fibre
Bunzel, M., Ralph, J., Marita, J. M., Hatfield, R. D., & Steinhart, H. (2001) · Journal of the Science of Food and Agriculture · doi:10.1002/jsfa.861 · Cited by 328
A rapid method for the determination of pentosans in wheat flour
DOUGLAS, S. (1981) · Food Chemistry · doi:10.1016/0308-8146(81)90059-5 · Cited by 326
Aura, A.-M., O'Leary, K. A., Williamson, G., Ojala, M., Bailey, M., Puupponen-Pimiä, R., Nuutila, A. M., Oksman-Caldentey, K.-M., & Poutanen, K. (2002) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf0108056 · Cited by 306
Self-citationAndreasen, M. F., Kroon, P. A., Williamson, G., & Garcia-Conesa, M.-T. (2001) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf010668c · Cited by 299
Bioavailability and metabolism
Stahl, W. (2002) · Molecular Aspects of Medicine · doi:10.1016/s0098-2997(02)00016-x · Cited by 286
Gibson, G. R., Cummings, J. H., & Macfarlane, G. T. (1988) · Applied and Environmental Microbiology · doi:10.1128/aem.54.11.2750-2755.1988 · Cited by 285
Bioavailability of ferulic acid is determined by its bioaccessibility
Mateo Anson, N., van den Berg, R., Havenaar, R., Bast, A., & Haenen, G. R. M. M. (2009) · Journal of Cereal Science · doi:10.1016/j.jcs.2008.12.001 · Cited by 253
Self-citationGonthier, M.-P., Remesy, C., Scalbert, A., Cheynier, V., Souquet, J.-M., Poutanen, K., & Aura, A.-M. (2006) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2006.07.084 · Cited by 246
Self-citationEffects of UV-B on flavonoids, ferulic acid, growth and photosynthesis in barley primary leaves
Liu, L., Gitz Iii, D. C., & McClure, J. W. (1995) · Physiologia Plantarum · doi:10.1034/j.1399-3054.1995.930421.x · Cited by 238
Digestion and Absorption of Ferulic Acid Sugar Esters in Rat Gastrointestinal Tract
Zhao, Z., Egashira, Y., & Sanada, H. (2003) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf034455u · Cited by 130
Ferulic Acid from Aleurone Determines the Antioxidant Potency of Wheat Grain (Triticum aestivum L.)
Anson, N. M., van den Berg, R., Havenaar, R., Bast, A., & Haenen, G. R. M. M. (2008) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf800445k · Cited by 130
Self-citationHydroxycinnamic acids in the digestive tract of livestock and humans
Chesson, A., Provan, G. J., Russell, W. R., Scobbie, L., Richardson, A. J., & Stewart, C. S. (1999) · Journal of the Science of Food and Agriculture · doi:10.1002/(sici)1097-0010(19990301)79:3<373::aid-jsfa257>3.0.co;2-6 · Cited by 121
Bartolom�, B., & G�mez-Cordov�s, C. (1999) · Journal of the Science of Food and Agriculture · doi:10.1002/(sici)1097-0010(19990301)79:3<435::aid-jsfa272>3.0.co;2-s · Cited by 115
Larsson, M., Minekus, M., & Havenaar, R. (1997) · Journal of the Science of Food and Agriculture · Cited by 94
Self-citationAnti-Inflammatory Implications of the Microbial Transformation of Dietary Phenolic Compounds
Russell, W. R., Scobbie, L., Chesson, A., Richardson, A. J., Stewart, C. S., Duncan, S. H., Drew, J. E., & Duthie, G. G. (2008) · Nutrition and Cancer · doi:10.1080/01635580801987498 · Cited by 86
Glei, M., Hofmann, T., Küster, K., Hollmann, J., Lindhauer, M. G., & Pool-Zobel, B. L. (2006) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf052768e · Cited by 70
Cited by
Relevance and challenges in modeling human gastric and small intestinal digestion
Guerra, A., Etienne-Mesmin, L., Livrelli, V., Denis, S., Blanquet-Diot, S., & Alric, M. (2012) · Trends in Biotechnology · doi:10.1016/j.tibtech.2012.08.001 · Cited by 564
Sourdough and cereal fermentation in a nutritional perspective
Poutanen, K., Flander, L., & Katina, K. (2009) · Food Microbiology · doi:10.1016/j.fm.2009.07.011 · Cited by 537
Self-citationFlieger, J., Flieger, W., Baj, J., & Maciejewski, R. (2021) · Materials · doi:10.3390/ma14154135 · Cited by 441
How the sourdough may affect the functional features of leavened baked goods
Gobbetti, M., Rizzello, C. G., Di Cagno, R., & De Angelis, M. (2014) · Food Microbiology · doi:10.1016/j.fm.2013.04.012 · Cited by 397
Etcheverry, P., Grusak, M. A., & Fleige, L. E. (2012) · Frontiers in Physiology · doi:10.3389/fphys.2012.00317 · Cited by 391
Metadata
- Authors
- Anson, N. M., Selinheimo, E., Havenaar, R., Aura, A.-M., Mattila, I., Lehtinen, P., Bast, A., Poutanen, K., & Haenen, G. R. M. M.
- Venue
- Journal of Agricultural and Food Chemistry
- Publisher
- American Chemical Society (ACS)
- Published
- 2009-06-18
- Volume
- 57
- Issue
- 14
- Pages
- 6148-6155
- ISSN
- 0021-8561 (ISSN-L)
- 1520-5118
- OpenAlex
- W2118607803
- Cited by
- 255
- References
- 31
- FWCI
- 6.35
- Type
- journal article
- Language
- en
- Open access
- closed
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