Prediction of aggregation prone regions of therapeutic proteins

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Scalable molecular dynamics with NAMD

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Protein Misfolding, Functional Amyloid, and Human Disease

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Prediction of sequence-dependent and mutational effects on the aggregation of peptides and proteins

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Physical Stability of Proteins in Aqueous Solution: Mechanism and Driving Forces in Nonnative Protein Aggregation

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Effects of protein aggregates: An immunologic perspective

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Potent antibody therapeutics by design

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Rationalization of the effects of mutations on peptide andprotein aggregation rates

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Crystal Structure of a Neutralizing Human IgG Against HIV-1: A Template for Vaccine Design

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Challenges in the development of high protein concentration formulations

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Standard conformations for the canonical structures of immunoglobulins 1 1Edited by I. A. Wilson

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Convergent Solutions to Binding at a Protein-Protein Interface

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Challenges in the Development of High Protein Concentration Formulations

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Structure-Immunogenicity Relationships of Therapeutic Proteins

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Design of therapeutic proteins with enhanced stability

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Studies of protein‐protein interfaces: A statistical analysis of the hydrophobic effect

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A role for surface hydrophobicity in protein‐protein recognition

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Development of hydrophobicity parameters to analyze proteins which bear post- or cotranslational modifications

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Molecular dynamics simulations of spontaneous fibril formation by random-coil peptides

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Dissecting the Assembly of Aβ16–22 Amyloid Peptides into Antiparallel β Sheets

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Protein Aggregates Seem to Play a Key Role Among the Parameters Influencing the Antigenicity of Interferon Alpha (IFN-α) in Normal and Transgenic Mice

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Carbohydrate solution simulations: Producing a force field with experimentally consistent primary alcohol rotational frequencies and populations

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The role of side-chain interactions in the early steps of aggregation: Molecular dynamics simulations of an amyloid-forming peptide from the yeast prion Sup35

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Conservation and relative importance of residues across protein-protein interfaces

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Prediction of aggregation rate and aggregation‐prone segments in polypeptide sequences

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Immunogenicity of biopharmaceuticals

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Insight into the Structure of Amyloid Fibrils from the Analysis of Globular Proteins

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Potential aggregation prone regions in biotherapeutics: A survey of commercial monoclonal antibodies

Wang, X., Das, T. K., Singh, S. K., & Kumar, S. (2009) · mAbs · doi:10.4161/mabs.1.3.8035 · Cited by 198 · see citing works

Kinetics of Irreversible Protein Aggregation: Analysis of Extended Lumry−Eyring Models and Implications for Predicting Protein Shelf Life

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Exploring protein aggregation and self‐propagation using lattice models: Phase diagram and kinetics

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WAM: an improved algorithm for modelling antibodies on the WEB

Whitelegg, N., & Rees, A. R. (2000) · Protein Engineering Design and Selection · doi:10.1093/protein/13.12.819 · Cited by 159 · see citing works

A Role for Protein Misfolding in Immunogenicity of Biopharmaceuticals

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Aggregation-Prone Motifs in Human Immunoglobulin G

Chennamsetty, N., Helk, B., Voynov, V., Kayser, V., & Trout, B. L. (2009) · Journal of Molecular Biology · doi:10.1016/j.jmb.2009.06.028 · Cited by 156 · see citing works

Lumry−Eyring Nucleated-Polymerization Model of Protein Aggregation Kinetics. 2. Competing Growth via Condensation and Chain Polymerization

Li, Y., & Roberts, C. J. (2009) · The Journal of Physical Chemistry B · doi:10.1021/jp8083088 · Cited by 140 · see citing works

Natively Unfolded Protein Stability as a Coil-to-Globule Transition in Charge/Hydropathy Space

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Computational models for the prediction of polypeptide aggregation propensity

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What's fueling the biotech engine?

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Thermodynamics of model prions and its implications for the problem of prion protein folding 1 1Edited by A. R. Fersht

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Predictive tools for stabilization of therapeutic proteins

Voynov, V., Chennamsetty, N., Kayser, V., Helk, B., & Trout, B. L. (2009) · mAbs · doi:10.4161/mabs.1.6.9773 · Cited by 78 · see citing works

Folding and aggregation of designed proteins

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Protein aggregation in silico

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Amyloid-Like Self-Assembly of Peptide Sequences from the Adenovirus Fiber Shaft: Insights from Molecular Dynamics Simulations

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Energy transduction during catalysis by Escherichia coli DNA photolyase

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Energy Landscapes Associated with the Self-Aggregation of an Alanine-Based Oligopeptide (AAKA) 4

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ProGen2: Exploring the boundaries of protein language models

Nijkamp, E., Ruffolo, J. A., Weinstein, E. N., Naik, N., & Madani, A. (2023) · Cell Systems · doi:10.1016/j.cels.2023.10.002 · Cited by 480 · see citing works

Developability Assessment During the Selection of Novel Therapeutic Antibodies

Jarasch, A., Koll, H., Regula, J. T., Bader, M., Papadimitriou, A., & Kettenberger, H. (2015) · Journal of Pharmaceutical Sciences · doi:10.1002/jps.24430 · Cited by 242 · see citing works

Predicting antibody developability profiles through early stage discovery screening

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Computational approaches to therapeutic antibody design: established methods and emerging trends

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Proteins behaving badly: emerging technologies in profiling biopharmaceutical aggregation

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Prediction of delayed retention of antibodies in hydrophobic interaction chromatography from sequence using machine learning

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Development of scoring functions for antibody sequence assessment and optimization

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ИСПОЛЬЗОВAНИЕ ПОТЕНЦИAЛA СОЦИAЛЬНЫХ ПAРТНЕРОВ В ПОДГОТОВКЕ БУДУЩИХ ПЕДAГОГОВ

Атабекова, Б. Б. (2024) · Habaršy. Pedagogika ġylymdary seriâsy · doi:10.51889/2959-5762.2023.80.4.019

Susquehanna Chorale Spring Concert "Roots and Wings"

Hawkins, D. (2017)

Using DataGrid Control to Realize DataBase of Querying in VB6.0

Hu, S. (2000) · Modern Computer

Study and Two Types of Typical Usage of DataGrid Web Server Control

Hai-tao, L. (2005) · Modern Computer

STKVS: secure technique for keyframes-based video summarization model

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