The DOI matches its Crossref record; 29 of the 29 references it cites were found in a registry or an index.
Tracking Individual Kinesin Motors in Living Cells Using Single Quantum-Dot Imaging
Abstract
We report a simple method using semiconductor quantum dots (QDs) to track the motion of intracellular proteins with a high sensitivity. We characterized the in vivo motion of individual QD-tagged kinesin motors in living HeLa cells. Single-molecule measurements provided important parameters of the motor, such as its velocity and processivity, as well as an estimate of the force necessary to carry a QD. Our measurements demonstrate the importance of single-molecule experiments in the investigation of intracellular transport as well as the potential of single quantum-dot imaging for the study of important processes such as cellular trafficking, cell polarization, and division.
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Cites
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Metadata
- Authors
- Courty, S., Luccardini, C., Bellaiche, Y., Cappello, G., & Dahan, M.
- Venue
- Nano Letters
- Publisher
- American Chemical Society (ACS)
- Published
- 2006-06-23
- Volume
- 6
- Issue
- 7
- Pages
- 1491-1495
- ISSN
- 1530-6984 (ISSN-L)
- 1530-6992
- OpenAlex
- W2117116692
- Cited by
- 324
- References
- 29
- FWCI
- 10.73
- Type
- journal article
- Language
- en
- Open access
- closed
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