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Patterned Multiplex Pathogen DNA Detection by Au Particle-on-Wire SERS Sensor
Abstract
A Au particle-on-wire system that can be used as a specific, sensitive, and multiplex DNA sensor is developed. A pattern formed by multiple Au nanowire sensors provides positional address and identification for each sensor. By using this system, multiplex sensing of target DNAs was possible in a quantitative manner with a detection limit of 10 pM. Target DNAs from reference bacteria and clinical isolates were successfully identified by this sensor system, enabling diagnostics for infectious diseases.
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Metadata
- Authors
- Kang, T., Yoo, S. M., Yoon, I., Lee, S. Y., & Kim, B.
- Venue
- Nano Letters
- Publisher
- American Chemical Society (ACS)
- Published
- 2010-03-11
- Volume
- 10
- Issue
- 4
- Pages
- 1189-1193
- ISSN
- 1530-6984 (ISSN-L)
- 1530-6992
- OpenAlex
- W2052316114
- Cited by
- 374
- References
- 2
- FWCI
- 12.91
- Type
- journal article
- Language
- en
- Open access
- closed
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