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Cited by 818

The DOI matches its Crossref record; 28 of the 28 references it cites were found in a registry or an index.

Annonaceous Acetogenins: Recent Progress

Alali, Feras Q., Liu, Xiao-Xi, McLaughlin, Jerry L.·1999·Journal of Natural Products

Abstract

The Annonaceous acetogenins are promising new antitumor and pesticidal agents that are found only in the plant family Annonaceae. Chemically, they are derivatives of long-chain fatty acids. Biologically, they exhibit their potent bioactivities through depletion of ATP levels via inhibiting complex I of mitochondria and inhibiting the NADH oxidase of plasma membranes of tumor cells. Thus, they thwart ATP-driven resistance mechanisms. This review presents the progress made in the chemistry, biology, and development of these compounds since December 1995.

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Crossref · 10.1021/np980406d

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Metadata

Authors
Alali, F. Q., Liu, X.-X., & McLaughlin, J. L.
Venue
Journal of Natural Products
Published
1999-03-01
Volume
62
Issue
3
Pages
504-540
ISSN
  • 0163-3864 (ISSN-L)
  • 1520-6025
OpenAlex
W2142576295
Cited by
818
References
28
FWCI
8.99
Type
journal article
Language
en
Open access
closed

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