Proteomic Identification of Carbonylated Proteins and Their Oxidation Sites

Probability-based protein identification by searching sequence databases using mass spectrometry data

Perkins, D. N., Pappin, D. J. C., Creasy, D. M., & Cottrell, J. S. (1999) · Electrophoresis · doi:10.1002/(sici)1522-2683(19991201)20:18<3551::aid-elps3551>3.0.co;2-2 · Cited by 8,203

The Pathobiology of Diabetic Complications

Brownlee, M. (2005) · Diabetes · doi:10.2337/diabetes.54.6.1615 · Cited by 5,339

Oxidative Stress and Neurodegenerative Diseases: A Review of Upstream and Downstream Antioxidant Therapeutic Options

Uttara, B., Singh, A., Zamboni, P., & Mahajan, R. (2009) · Current Neuropharmacology · doi:10.2174/157015909787602823 · Cited by 3,378

Protein Oxidation in Aging, Disease, and Oxidative Stress

Berlett, B. S., & Stadtman, E. R. (1997) · Journal of Biological Chemistry · doi:10.1074/jbc.272.33.20313 · Cited by 3,332

A generic protein purification method for protein complex characterization and proteome exploration

Rigaut, G., Shevchenko, A., Rutz, B., Wilm, M., Mann, M., & Séraphin, B. (1999) · Nature Biotechnology · doi:10.1038/13732 · Cited by 2,707

Protein carbonyl groups as biomarkers of oxidative stress

Dalle-Donne, I., Rossi, R., Giustarini, D., Milzani, A., & Colombo, R. (2003) · Clinica Chimica Acta · doi:10.1016/s0009-8981(03)00003-2 · Cited by 2,349

Proteomic analysis of post-translational modifications

Mann, M., & Jensen, O. N. (2003) · Nature Biotechnology · doi:10.1038/nbt0303-255 · Cited by 2,134

Free radical-mediated oxidation of free amino acids and amino acid residues in proteins

Stadtman, E. R., & Levine, R. L. (2003) · Amino Acids · doi:10.1007/s00726-003-0011-2 · Cited by 1,962

Protein damage and degradation by oxygen radicals. I. general aspects.

Davies, K. J. (1987) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)48018-0 · Cited by 1,634

Avidin

Green, N. M. (1975) · Advances in Protein Chemistry · doi:10.1016/s0065-3233(08)60411-8 · Cited by 1,458

Selected reaction monitoring for quantitative proteomics: a tutorial

Lange, V., Picotti, P., Domon, B., & Aebersold, R. (2008) · Molecular Systems Biology · doi:10.1038/msb.2008.61 · Cited by 1,407

Protein Oxidation

STADTMAN, E. R., & LEVINE, R. L. (2000) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.2000.tb06187.x · Cited by 1,007

Quantitative, Multiplexed Assays for Low Abundance Proteins in Plasma by Targeted Mass Spectrometry and Stable Isotope Dilution

Keshishian, H., Addona, T., Burgess, M., Kuhn, E., & Carr, S. A. (2007) · Molecular & Cellular Proteomics · doi:10.1074/mcp.m700354-mcp200 · Cited by 684

Protein Oxidation in Aging and Age‐Related Diseases

Stadtman, E. R. (2001) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.2001.tb05632.x · Cited by 660

Reactive Oxygen-Mediated Protein Oxidation in Aging and Disease

Stadtman, E. R., & Berlett, B. S. (1997) · Chemical Research in Toxicology · doi:10.1021/tx960133r · Cited by 645

The role of oxidative damage and stress in aging

Bokov, A., Chaudhuri, A., & Richardson, A. (2004) · Mechanisms of Ageing and Development · doi:10.1016/j.mad.2004.07.009 · Cited by 624

Is the oxidative stress theory of aging dead?

Pérez, V. I., Bokov, A., Remmen, H. V., Mele, J., Ran, Q., Ikeno, Y., & Richardson, A. (2009) · Biochimica et Biophysica Acta (BBA) - General Subjects · doi:10.1016/j.bbagen.2009.06.003 · Cited by 604

Proteomic identification of oxidatively modified proteins in Alzheimer’s disease brain. Part I: Creatine kinase BB, glutamine synthase, and ubiquitin carboxy-terminal hydrolase L-1

Castegna, A., Aksenov, M., Aksenova, M., Thongboonkerd, V., Klein, J. B., Pierce, W. M., Booze, R., Markesbery, W. R., & Butterfield, D. A. (2002) · Free Radical Biology and Medicine · doi:10.1016/s0891-5849(02)00914-0 · Cited by 581

Conversion of Amino Acid Residues in Proteins and Amino Acid Homopolymers to Carbonyl Derivatives by Metal-catalyzed Oxidation Reactions

Amici, A., Levine, R. L., Tsai, L., & Stadtman, E. R. (1989) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)94071-8 · Cited by 500

Update on the oxidative stress theory of aging: Does oxidative stress play a role in aging or healthy aging?

Salmon, A. B., Richardson, A., & Pérez, V. I. (2010) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2009.12.015 · Cited by 446

Protein Glycation: A Firm Link to Endothelial Cell Dysfunction

Wautier, J.-L., & Schmidt, A. M. (2004) · Circulation Research · doi:10.1161/01.res.0000137876.28454.64 · Cited by 436

Protein stability and resistance to oxidative stress are determinants of longevity in the longest-living rodent, the naked mole-rat

Pérez, V. I., Buffenstein, R., Masamsetti, V., Leonard, S., Salmon, A. B., Mele, J., Andziak, B., Yang, T., Edrey, Y., Friguet, B., et al. (2009) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0809620106 · Cited by 418

Glutamic and aminoadipic semialdehydes are the main carbonyl products of metal-catalyzed oxidation of proteins

Requena, J. R., Chao, C.-C., Levine, R. L., & Stadtman, E. R. (2001) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.98.1.69 · Cited by 415

Methionine oxidation and aging

Stadtman, E. R., Van Remmen, H., Richardson, A., Wehr, N. B., & Levine, R. L. (2005) · Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics · doi:10.1016/j.bbapap.2004.08.010 · Cited by 400

Oxidative stress in Alzheimer's disease brain: New insights from redox proteomics

Butterfield, D. A., Perluigi, M., & Sultana, R. (2006) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2006.06.026 · Cited by 363

High Sensitivity Detection of Plasma Proteins by Multiple Reaction Monitoring of N-Glycosites

Stahl-Zeng, J., Lange, V., Ossola, R., Eckhardt, K., Krek, W., Aebersold, R., & Domon, B. (2007) · Molecular & Cellular Proteomics · doi:10.1074/mcp.m700132-mcp200 · Cited by 361

Fragmentation of proteins by free radicals and its effect on their susceptibility to enzymic hydrolysis

Wolff, S. P., & Dean, R. T. (1986) · Biochemical Journal · doi:10.1042/bj2340399 · Cited by 349

Oxidative Stress, Endothelial Dysfunction and Atherosclerosis

Victor, V., Rocha, M., Sola, E., Banuls, C., Garcia-Malpartida, K., & Hernandez- Mijares, A. (2009) · Current Pharmaceutical Design · doi:10.2174/138161209789058093 · Cited by 264

Redox proteomic identification of 4-Hydroxy-2-nonenal-modified brain proteins in amnestic mild cognitive impairment: Insight into the role of lipid peroxidation in the progression and pathogenesis of Alzheimer's disease

Reed, T., Perluigi, M., Sultana, R., Pierce, W. M., Klein, J. B., Turner, D. M., Coccia, R., Markesbery, W. R., & Butterfield, D. A. (2008) · Neurobiology of Disease · doi:10.1016/j.nbd.2007.12.007 · Cited by 257

Carbonylation of Adipose Proteins in Obesity and Insulin Resistance

Grimsrud, P. A., Picklo, M. J., Griffin, T. J., & Bernlohr, D. A. (2007) · Molecular & Cellular Proteomics · doi:10.1074/mcp.m600120-mcp200 · Cited by 249

Atti della Accademia nazionale dei Lincei

Lincei, A. N. D. (1887) · Cited by 229

Redox proteomics identification of 4-hydroxynonenal-modified brain proteins in Alzheimer’s disease: Role of lipid peroxidation in Alzheimer’s disease pathogenesis

Perluigi, M., Sultana, R., Cenini, G., Di Domenico, F., Memo, M., Pierce, W. M., Coccia, R., & Butterfield, D. A. (2009) · PROTEOMICS - CLINICAL APPLICATIONS · doi:10.1002/prca.200800161 · Cited by 196

Redox proteomics: from protein modifications to cellular dysfunction and disease

Butterfield, D. A., & Dalle‐Donne, I. (2014) · Mass Spectrometry Reviews · doi:10.1002/mas.21404 · Cited by 182

Modification of Heat Shock Protein 90 by 4-Hydroxynonenal in a Rat Model of Chronic Alcoholic Liver Disease

Carbone, D. L., Doorn, J. A., Kiebler, Z., Ickes, B. R., & Petersen, D. R. (2005) · The Journal of Pharmacology and Experimental Therapeutics · doi:10.1124/jpet.105.088088 · Cited by 175

Enzymatic digestion and mass spectrometry in the study of advanced glycation end products/peptides

Lapolla, A., Fedele, D., Reitano, R., Aricò, N. C., Seraglia, R., Traldi, P., Marotta, E., & Tonani, R. (2004) · Journal of the American Society for Mass Spectrometry · doi:10.1016/j.jasms.2003.11.014 · Cited by 164

The proteasome and its role in the degradation of oxidized proteins

Jung, T., & Grune, T. (2008) · IUBMB Life · doi:10.1002/iub.114 · Cited by 164

Enrichment and Analysis of Nonenzymatically Glycated Peptides: Boronate Affinity Chromatography Coupled with Electron-Transfer Dissociation Mass Spectrometry

Zhang, Q., Tang, N., Brock, J. W. C., Mottaz, H. M., Ames, J. M., Baynes, J. W., Smith, R. D., & Metz, T. O. (2007) · Journal of Proteome Research · doi:10.1021/pr070112q · Cited by 161

Oxidative Stress in Breast Cancer

Taş, F., Hansel, H., Belce, A., et al. (2005) · Medical Oncology · doi:10.1385/mo:22:1:011 · Cited by 158

Detection of protein carbonyls in aging liver tissue: A fluorescence-based proteomic approach

Chaudhuri, A. R., de Waal, E. M., Pierce, A. P., Remmen, H. V., Ward, W. F., & Richardson, A. G. (2006) · Mechanisms of Ageing and Development · doi:10.1016/j.mad.2006.08.006 · Cited by 154

Identification of oxidised proteins in the matrix of rice leaf mitochondria by immunoprecipitation and two-dimensional liquid chromatography-tandem mass spectrometry

Kristensen, B. K., Askerlund, P., Bykova, N. V., Egsgaard, H., & Møller, I. M. (2004) · Phytochemistry · doi:10.1016/j.phytochem.2004.04.007 · Cited by 151

Rules Governing Selective Protein Carbonylation

Maisonneuve, E., Ducret, A., Khoueiry, P., Lignon, S., Longhi, S., Talla, E., & Dukan, S. (2009) · PLoS ONE · doi:10.1371/journal.pone.0007269 · Cited by 151

Direct Characterization of Protein Adducts of the Lipid Peroxidation Product 4-Hydroxy-2-nonenal Using Electrospray Mass Spectrometry

Bruenner, B. A., Jones, A. D., & German, J. B. (1995) · Chemical Research in Toxicology · doi:10.1021/tx00046a009 · Cited by 149

Affinity Chromatographic Selection of Carbonylated Proteins Followed by Identification of Oxidation Sites Using Tandem Mass Spectrometry

Mirzaei, H., & Regnier, F. E. (2005) · Analytical Chemistry · doi:10.1021/ac0484373 · Cited by 141

Modification of Cytochrome c by 4-hydroxy- 2-nonenal: Evidence for histidine, lysine, and arginine-aldehyde adducts

Isom, A., Barnes, S., Wilson, L. S., KIRK, M. C., Coward, L. U., & Darley-Usmar, V. M. (2004) · Journal of the American Society for Mass Spectrometry · doi:10.1016/j.jasms.2004.03.013 · Cited by 141

Proteomic identification of proteins oxidized by Aβ(1–42) in synaptosomes: Implications for Alzheimer's disease

Debra Boyd-kimball, A., Castegna, A., Rukhsana Sultana, A., Poon, H. F., Petroze, R. T., Lynn, B. C., Klein, J. B., & Butterfield, D. A. (2005) · Brain Research · doi:10.1016/j.brainres.2005.02.086 · Cited by 141

Rapid and simple single nanogram detection of glycoproteins in polyacrylamide gels and on electroblots

Steinberg, T. H., Top, K. P. O., Berggren, K. N., Kemper, C., Jones, L. J., Diwu, Z. J., Haugland, R. P., & Patton, W. F. (2001) · PROTEOMICS · doi:10.1002/1615-9861(200107)1:7<829::aid-prot829>3.0.co;2-r · Cited by 140

Quantitative proteomics analysis of differential protein expression and oxidative modification of specific proteins in the brains of old mice

Poon, H. F., Vaishnav, R., Getchell, T. V., Getchell, M. L., & Butterfield, D. A. (2005) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2005.05.006 · Cited by 133

Proteomic analysis of specific brain proteins in aged SAMP8 mice treated with alpha-lipoic acid: implications for aging and age-related neurodegenerative disorders

Poon, H. F., Farr, S. A., Thongboonkerd, V., Lynn, B. C., Banks, W. A., Morley, J. E., Klein, J. B., & Butterfield, D. A. (2004) · Neurochemistry International · doi:10.1016/j.neuint.2004.07.008 · Cited by 128

Redox Proteomics Identification of Oxidatively Modified Brain Proteins in Alzheimer's Disease and Mild Cognitive Impairment: Insights into the Progression of this Dementing Disorder

Butterfield, D. A., & Rukhsana Sultana, A. (2007) · Journal of Alzheimer s Disease · doi:10.3233/jad-2007-12107 · Cited by 126

Molecular Basis of Enzyme Inactivation by an Endogenous Electrophile 4-Hydroxy-2-nonenal: Identification of Modification Sites in Glyceraldehyde-3-phosphate Dehydrogenase

Ishii, T., Tatsuda, E., Kumazawa, S., Nakayama, T., & Uchida, K. (2003) · Biochemistry · doi:10.1021/bi027172o · Cited by 118

Identification of carbonylated proteins from enriched rat skeletal muscle mitochondria using affinity chromatography‐stable isotope labeling and tandem mass spectrometry

Meany, D. L., Xie, H., Thompson, L. V., Arriaga, E. A., & Griffin, T. J. (2007) · PROTEOMICS · doi:10.1002/pmic.200600450 · Cited by 116

Proteomic Profiling of Nonenzymatically Glycated Proteins in Human Plasma and Erythrocyte Membranes

Zhang, Q., Tang, N., Schepmoes, A., Phillips, L. S., Smith, R. D., & Metz, T. (2008) · Journal of Proteome Research · doi:10.1021/pr700763r · Cited by 115

Mass spectrometric characterization of covalent modification of human serum albumin by 4‐hydroxy‐trans‐2‐nonenal

Aldini, G., Gamberoni, L., Orioli, M., Beretta, G., Regazzoni, L., Facino, R. M., & Carini, M. (2006) · Journal of Mass Spectrometry · doi:10.1002/jms.1067 · Cited by 115

Proteomic analysis of carbonylated proteins in two‐dimensional gel electrophoresis using avidin‐fluorescein affinity staining

Yoo, B., & Regnier, F. E. (2004) · Electrophoresis · doi:10.1002/elps.200405890 · Cited by 114

High-Throughput Proteomic-Based Identification of Oxidatively Induced Protein Carbonylation in Mouse Brain

Soreghan, B. A., Yang, F. F., Thomas, S. N., Hsu, J. L., & Yang, A. J. (2003) · Pharmaceutical Research · doi:10.1023/b:pham.0000003366.25263.78 · Cited by 112

Profiling Carbonylated Proteins in Human Plasma

Madian, A. G., & Regnier, F. E. (2010) · Journal of Proteome Research · doi:10.1021/pr900890k · Cited by 104

Mass Spectroscopic Characterization of Protein Modification by 4-Hydroxy-2-(E)-nonenal and 4-Oxo-2-(E)-nonenal

Liu, Z., Minkler, P. E., & Sayre, L. M. (2003) · Chemical Research in Toxicology · doi:10.1021/tx0300030 · Cited by 102

Identification of specific protein carbonylation sites in model oxidations of human serum albumin

Temple, A., Yen, T., & Gronert, S. (2006) · Journal of the American Society for Mass Spectrometry · doi:10.1016/j.jasms.2006.04.030 · Cited by 101

Proteomic Mapping of 4-Hydroxynonenal Protein Modification Sites by Solid-Phase Hydrazide Chemistry and Mass Spectrometry

Roe, M. R., Xie, H., Bandhakavi, S., & Griffin, T. J. (2007) · Analytical Chemistry · doi:10.1021/ac0617971 · Cited by 93

Protein:protein aggregation induced by protein oxidation

Mirzaei, H., & Regnier, F. E. (2008) · Journal of Chromatography B · doi:10.1016/j.jchromb.2008.04.025 · Cited by 90

Expression and Carbonylation of Creatine Kinase in the Quadriceps Femoris Muscles of Patients with Chronic Obstructive Pulmonary Disease

Barreiro, E., Gea, J., Matar, G., & Hussain, S. N. A. (2005) · American Journal of Respiratory Cell and Molecular Biology · doi:10.1165/rcmb.2005-0114oc · Cited by 89

Long-Lived Ames Dwarf Mice Are Resistant to Chemical Stressors

Bokov, A. F., Lindsey, M. L., Khodr, C. E., Sabia, M. R., & Richardson, A. G. (2009) · The Journals of Gerontology Series A · doi:10.1093/gerona/glp052 · Cited by 87

Study of protein modification by 4-hydroxy-2-nonenal and other short chain aldehydes analyzed by electrospray ionization tandem mass spectrometry

Fenaille, F., Guy, P. A., & Tabet, J. (2003) · Journal of the American Society for Mass Spectrometry · doi:10.1016/s1044-0305(02)00911-x · Cited by 85

Determination of the Sites of 4-Hydroxy-2-nonenal Adduction to Protein by Electrospray Tandem Mass Spectrometry

Bolgar, M. S., & Gaskell, S. J. (1996) · Analytical Chemistry · doi:10.1021/ac9601021 · Cited by 84

Application of electron transfer dissociation mass spectrometry in analyses of non‐enzymatically glycated peptides

Zhang, Q., Frolov, A., Tang, N., Hoffmann, R., van de Goor, T., Metz, T., & Smith, R. D. (2007) · Rapid Communications in Mass Spectrometry · doi:10.1002/rcm.2884 · Cited by 84

Quantitative Proteomic Profiling of Muscle Type-Dependent and Age-Dependent Protein Carbonylation in Rat Skeletal Muscle Mitochondria

Feng, J., Xie, H., Meany, D. L., Thompson, L. V., Arriaga, E. A., & Griffin, T. J. (2008) · The Journals of Gerontology Series A · doi:10.1093/gerona/63.11.1137 · Cited by 83

New Role for an Old Probe: Affinity Labeling of Oxylipid Protein Conjugates byN‘-Aminooxymethylcarbonylhydrazino d -biotin

Chavez, J. D., Wu, J., Han, B., Chung, W., & Maier, C. S. (2006) · Analytical Chemistry · doi:10.1021/ac0607257 · Cited by 82

Proteomic Analysis of the Site Specificity of Glycation and Carboxymethylation of Ribonuclease

Brock, J. W. C., Hinton, D. J. S., Cotham, W. E., Metz, T., Thorpe, S. R., Baynes, J., & Ames, J. M. (2003) · Journal of Proteome Research · doi:10.1021/pr0340173 · Cited by 82

Enrichment of Carbonylated Peptides Using Girard P Reagent and Strong Cation Exchange Chromatography

Mirzaei, H., & Regnier, F. E. (2005) · Analytical Chemistry · doi:10.1021/ac0514220 · Cited by 81

Proteomic identification of carbonylated proteins in the monkey hippocampus after ischemia–reperfusion

Oikawa, S., Yamada, T., Minohata, T., Kobayashi, H., Furukawa, A., Tada‐Oikawa, S., Hiraku, Y., Murata, M., Kikuchi, M., & Yamashima, T. (2009) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2009.02.029 · Cited by 81

Retinal proteins modified by 4-hydroxynonenal: Identification of molecular targets

Kapphahn, R. J., Giwa, B. M., Berg, K. M., et al. (2006) · Experimental Eye Research · doi:10.1016/j.exer.2005.11.017 · Cited by 81

Proteomics in animal models of Alzheimer's and Parkinson's diseases

Robinson, R. A. S., Owen, J. B., & Butterfield, D. A. (2008) · Ageing Research Reviews · doi:10.1016/j.arr.2008.07.003 · Cited by 81

Screening and Sequencing of Glycated Proteins by Neutral Loss Scan LC/MS/MS Method

Gadgil, H. S., Bondarenko, P. V., Treuheit, M. J., & Ren, D. (2007) · Analytical Chemistry · doi:10.1021/ac070619k · Cited by 77

Proteomic method detects oxidatively induced protein carbonyls in muscles of a diabetes model Otsuka Long-evans Tokushima Fatty (OLETF) rat

Oh-Ishi, M., Ueno, T., & Maeda, T. (2002) · Free Radical Biology and Medicine · doi:10.1016/s0891-5849(02)01239-x · Cited by 72

GAPDH Is Conformationally and Functionally Altered in Association with Oxidative Stress in Mouse Models of Amyotrophic Lateral Sclerosis

Pierce, A. P., Mirzaei, H., Müller, F. L., de Waal, E., Taylor, A. B., Leonard, S., Remmen, H. V., Regnier, F. E., Richardson, A., & Chaudhuri, A. R. (2008) · Journal of Molecular Biology · doi:10.1016/j.jmb.2008.07.088 · Cited by 72

Recent advancements in differential proteomics based on stable isotope coding

Julka, S., & Regnier, F. E. (2005) · Briefings in Functional Genomics and Proteomics · doi:10.1093/bfgp/4.2.158 · Cited by 72

Redox Proteomics: From Protein Modifications to Cellular Dysfunction and Diseases

(2006) · doi:10.1002/0471973122 · Cited by 70

Carbonylated Proteins Are Detectable Only in a Degradation-Resistant Aggregate State in Escherichia coli

Maisonneuve, E., Fraysse, L., Lignon, S., et al. (2008) · Journal of Bacteriology · doi:10.1128/jb.00588-08 · Cited by 69

Identification of yeast oxidized proteins

Mirzaei, H., & Regnier, F. E. (2006) · Journal of Chromatography A · doi:10.1016/j.chroma.2006.11.009 · Cited by 68

First Direct Evidence for Lipid/Protein Conjugation in Oxidized Human Low Density Lipoprotein

Bolgar, M. S., Yang, C.-Y., & Gaskell, S. J. (1996) · Journal of Biological Chemistry · doi:10.1074/jbc.271.45.27999 · Cited by 66

Modifications of proteins by 4-hydroxy-2-nonenal in the ventilatory muscles of rats

Hussain, S. N. A., Matar, G., Barreiro, E., Florian, M., Divangahi, M., & Vassilakopoulos, T. P. (2006) · American Journal of Physiology-Lung Cellular and Molecular Physiology · doi:10.1152/ajplung.00337.2005 · Cited by 66

Design, Synthesis, and Application of a Hydrazide-Functionalized Isotope-Coded Affinity Tag for the Quantification of Oxylipid−Protein Conjugates

Han, B., Stevens, J. F., & Maier, C. S. (2007) · Analytical Chemistry · doi:10.1021/ac062262a · Cited by 65

Detection of Catalase as a major protein target of the lipid peroxidation product 4-HNE and the lack of its genetic association as a risk factor in SLE

D’Souza, A., Kurien, B. T., Rodgers, R., Shenoi, J., Kurono, S., Matsumoto, H., Hensley, K., Nath, S. K., & Scofield, R. H. (2008) · BMC Medical Genetics · doi:10.1186/1471-2350-9-62 · Cited by 64

Identification and quantification of protein carbonylation using light and heavy isotope labeled Girard's P reagent

Mirzaei, H., & Regnier, F. E. (2006) · Journal of Chromatography A · doi:10.1016/j.chroma.2006.08.096 · Cited by 58

Liver Proteome Analysis in a Rodent Model of Alcoholic Steatosis

Newton, B. W., Russell, W. K., Russell, D. H., Ramaiah, S. K., & Jayaraman, A. (2009) · Journal of Proteome Research · doi:10.1021/pr800905w · Cited by 58

Characterization of 4-Hydroxy-2-nonenal-Modified Peptides by Liquid Chromatography−Tandem Mass Spectrometry Using Data-Dependent Acquisition: Neutral Loss-Driven MS3 versus Neutral Loss-Driven Electron Capture Dissociation

Rauniyar, N., Stevens, S. M., Prókai-Tátrai, K., & Prókai, L. (2008) · Analytical Chemistry · doi:10.1021/ac802015m · Cited by 56

Shotgun proteome analysis of protein cleavage in apoptotic cells

Thiede, B., Treumann, A., Kretschmer, A., Söhlke, J., & Rudel, T. (2005) · PROTEOMICS · doi:10.1002/pmic.200401110 · Cited by 56

Oxidative modification and aggregation of creatine kinase from aged mouse skeletal muscle

Nuss, J. E., Amaning, J. K., Bailey, C. E., DeFord, J. H., Dimayuga, V. L., Rabek, J. P., & Papaconstantinou, J. (2009) · Aging · doi:10.18632/aging.100055 · Cited by 55

Redox proteomics: understanding oxidative stress in the progression of age-related neurodegenerative disorders

Butterfield, D. A., & Rukhsana Sultana, A. (2008) · Expert Review of Proteomics · doi:10.1586/14789450.5.2.157 · Cited by 54

Method to Site-Specifically Identify and Quantitate Carbonyl End Products of Protein Oxidation Using Oxidation-Dependent Element Coded Affinity Tags (O-ECAT) and NanoLiquid Chromatography Fourier Transform Mass Spectrometry

Lee, S., Young, N. L., Whetstone, P. A., Cheal, S. M., Benner, W. H., Lebrilla, C. B., & Meares, C. F. (2006) · Journal of Proteome Research · doi:10.1021/pr050299q · Cited by 52

Mass spectrometry‐based survey of age‐associated protein carbonylation in rat brain mitochondria

Prókai, L., Yan, L., Vera‐Serrano, J. L., Stevens, S. M., & Forster, M. J. (2007) · Journal of Mass Spectrometry · doi:10.1002/jms.1345 · Cited by 52

Characterization of advanced glycation end products: Mass changes in correlation to side chain modifications

Schmitt, A., Gasic‐Milenkovic, J., & Schmitt, J. (2005) · Analytical Biochemistry · doi:10.1016/j.ab.2005.07.035 · Cited by 52

Immunoaffinity Purification and Characterization of 4-Hydroxy-2-nonenal- and Malondialdehyde-Modified Peptides by Electrospray Ionization Tandem Mass Spectrometry

Fenaille, F., Tabet, J., & Guy, P. A. (2002) · Analytical Chemistry · doi:10.1021/ac020443g · Cited by 50

Advanced glycation end products: a highly complex set of biologically relevant compounds detected by mass spectrometry

Lapolla, A., Fedele, D., Martano, L., Aricò, C. N., Garbeglio, M., Traldi, P., Seraglia, R., & Favretto, D. (2001) · Journal of Mass Spectrometry · doi:10.1002/jms.137 · Cited by 50

Identification of oxidized proteins in rat plasma using avidin chromatography and tandem mass spectrometry

Mirzaei, H., Baena, B., Barbas, C., & Regnier, F. E. (2008) · PROTEOMICS · doi:10.1002/pmic.200700363 · Cited by 47

Creation of Allotypic Active Sites during Oxidative Stress

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The development of multiple reaction monitoring assays for liver‐derived plasma proteins

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