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Cited by 166Sexual Differentiation and DisordersHormonal and reproductive studiesGenetic Associations and Epidemiology

The DOI matches its Crossref record; 30 of the 30 references it cites were found in a registry or an index.

The Heritability of Testosterone: A Study of Dutch Adolescent Twins and Their Parents

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Harris, Julie Aitken, Vernon, Philip A., Boomsma, Dorret I.·1998·Behavior Genetics
DOI 10.1023/a:1021466929053
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Abstract

The heritability of total plasma testosterone levels, determined from blood samples, was examined in 160 adolescent twin pairs and their parents. Subjects were tested as part of a larger study of cardiovascular risk factors, conducted in Amsterdam. Each subject provided a sample of blood which was assayed to measure testosterone concentrations. Correlations of testosterone in monozygotic twins were higher than in dizygotic twins. No resemblance was found between testosterone values in fathers and those in their children and a moderate correlation was seen between mothers and their daughters. The lack of resemblance between family members of opposite sex suggests that different genetic factors influence plasma testosterone concentrations in men and women. In adolescent men, approximately 60% of the variance in testosterone levels is heritable. The lack of father-son resemblance suggests that different genetic factors may be expressed in adolescence and adulthood. In women, 40% of the variance in testosterone levels is heritable, both in adolescence and in adulthood.

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Crossref · 10.1023/a:1021466929053

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30 of 30 references verified0 citation errors · 0 not checkable

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Research works printed but not linked: 3

  1. Boomsma, D. I., Kempen, H. J. M., Gevers-Leuven, J. A., Havekes, L., de Knijff, P., and Frants, R. R. (1996). Genetic analysis of sex and generation differences in plasma lipid, lipoprotein and apolipoprotein levels in adolescent twins and their parents. Genet. Epidemiol. 13:49–60. · DOI
  2. Neale, M. C. (1997). Mx: Statistical Modeling, 2nd ed., Department of Psychiatry, Medical College of Virginia, Richmond.
  3. Rose, R. M. (1978). Neuroendocrine correlates of sexual and aggressive behavior in humans. In Lipton, M. A., DiMascio, A., and Killam, K. F. (eds.), Psychopharmacology: A Generation of Progress, Raven, New York, pp. 541–552.

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Metadata

Authors
Harris, J. A., Vernon, P. A., & Boomsma, D. I.
Affiliations
  • Western University (CA)
  • Vrije Universiteit Amsterdam (NL)
Corresponding author
Harris, Julie Aitken
ORCID
Boomsma, Dorret I.
Venue
Behavior Genetics
Publisher
Springer Science and Business Media LLC
Published
1998-05
Volume
28
Issue
3
Pages
165-171
ISSN
  • 0001-8244 (ISSN-L)
  • 1573-3297
DOI
10.1023/a:1021466929053
OpenAlex
W1602339315
Cited by
166
References
30
Citations by year
2026: 1 · 2024: 4 · 2023: 5 · 2022: 6 · 2021: 7 · 2020: 5 · 2019: 4 · 2018: 5 · 2017: 4 · 2016: 7 · 2015: 7 · 2014: 7 · 2013: 10 · 2012: 5
FWCI
1.18
Type
journal article
Language
en
Open access
Licence
Locations
  • Behavior Genetics (publishedVersion)
  • PubMed (publishedVersion)
  • VU Research Portal (publishedVersion, other-oa)
  • Digital Academic REpository of VU University Amsterdam (Vrije Universiteit Amsterdam) (submittedVersion)
  • Data Archiving and Networked Services (DANS) (submittedVersion, other-oa)
Topics
  • Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Sexual Differentiation and Disorders
  • Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Hormonal and reproductive studies
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Genetic Associations and Epidemiology
Keywords
testosterone, heritability, monozygotic twins, dizygotic twins, parent-offspring resemblance, sex differences, adolescent boys, adolescent girls, plasma testosterone
MeSH terms
Adolescent, Adult, Cross-Sectional Studies, Family Health, Female, Humans, Male, Middle Aged, Models, Genetic, Parents, Sex Factors, Testosterone, Twins, Dizygotic, Twins, Monozygotic, Cohort Studies, Chi-Square Distribution, Likelihood Functions

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