Marine pharmacology
Abstract
Marine organisms have provided a large proportion of the bioactive natural products reported over the last 20 years, but none of these compounds have reached the pharmaceutical marketplace. This review describes current progress in the development of a selection of new antiinflammatory and anticancer agents, discusses some difficulties encountered during the development process and suggests how these difficulties may be overcome in the near future through applications of recent advances in biotechnology.
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Some marine organisms, such as microflora, microalgae, macroalgae, invertebrate animals, sponges, soft corals, sea fans, sea hares, nudibranchs, bryozoans, tunicates, etc., have been investigated for cancer control.
“Furthermore, some marine organisms, such as microflora (bacteria, actinobacteria, cyanobacteria and fungi), microalgae, macroalgae (seaweeds) [31], invertebrate animals [37,38] sponges, soft corals, sea fans, sea hares, nudibranchs, bryozoans, tunicates, etc. [2], have been investigated for cancer control [39,40].”
From Marine Natural Products: A Source of Novel Anticancer Drugs (2019) · cites this paper as [40]
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Marine Natural Products: A Source of Novel Anticancer Drugs
Khalifa, S. A. M., Elias, N., Farag, M. A., Chen, L., Saeed, A., Hegazy, M.-E. F., Moustafa, M. S., Abd El-Wahed, A., Al-Mousawi, S. M., Musharraf, S. G., et al. (2019) · Marine Drugs · doi:10.3390/md17090491 · Cited by 555 · see citing works
“[2], have been investigated for cancer control [39,40].”
BackgroundBhadury, P., Mohammad, B. T., & Wright, P. C. (2006) · Journal of Industrial Microbiology & Biotechnology · doi:10.1007/s10295-005-0070-3 · Cited by 250 · see citing works
Evaluation of microalgae and cyanobacteria as potential sources of antimicrobial compounds
Alsenani, F., Tupally, K. R., Chua, E. T., Eltanahy, E., Alsufyani, H., Parekh, H. S., & Schenk, P. M. (2020) · Saudi Pharmaceutical Journal · doi:10.1016/j.jsps.2020.11.010 · Cited by 149 · see citing works
- Authors
- Faulkner, D. J.
- Affiliations
- Scripps Institution of Oceanography (US)
- Corresponding author
- Faulkner, D. John
- Venue
- Antonie van Leeuwenhoek
- Published
- 2000-02
- Volume
- 77
- Issue
- 2
- Pages
- 135-145
- ISSN
- 0003-6072 (ISSN-L)
- 1572-9699
- OpenAlex
- W4242920043
- Cited by
- 168
- References
- 47
- Citations by year
- 2025: 2 · 2024: 1 · 2023: 2 · 2022: 8 · 2021: 3 · 2020: 7 · 2019: 8 · 2018: 2 · 2017: 4 · 2016: 2 · 2015: 7 · 2014: 14 · 2013: 7 · 2012: 14
- FWCI
- 0.76
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- Locations
- Antonie van Leeuwenhoek (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Biotechnology › Marine Sponges and Natural Products
- Health Sciences › Medicine › Pharmacology › Microbial Natural Products and Biosynthesis
- Life Sciences › Agricultural and Biological Sciences › Aquatic Science › Seaweed-derived Bioactive Compounds
- Keywords
- marine natural products, bioactive compounds, anti-inflammatory agents, anticancer agents, drug development, marine organisms, biotechnology applications
- MeSH terms
- Biological Factors, Seawater
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