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Ethanol Effects on Apparent Solubility of Poorly Soluble Drugs in Simulated Intestinal Fluid

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Dissolution of Hydrocortisone in Human and Simulated Intestinal Fluids

Pedersen, B. L., BRØNDSTED, H. V., Lennernäs, H., Christensen, F. N., Müllertz, A., & Kristensen, H. G. (2000) · Pharmaceutical Research · doi:10.1023/a:1007517414200 · Cited by 82 · see citing works

Role of Physiological Intestinal Water in Oral Absorption

Sutton, S. C. (2009) · The AAPS Journal · doi:10.1208/s12248-009-9087-2 · Cited by 80 · see citing works

Prediction of the human oral bioavailability by using in vitro and in silico drug related parameters in a physiologically based absorption model

Paixão, P. J. P. A., Gouveia, L. F., & Morais, J. (2012) · International Journal of Pharmaceutics · doi:10.1016/j.ijpharm.2012.03.019 · Cited by 79 · see citing works

Analytical tools for the physicochemical profiling of drug candidates to predict absorption/distribution

Henchoz, Y., Bard, B., Guillarme, D., Carrupt, P., Veuthey, J., & Martel, S. (2009) · Analytical and Bioanalytical Chemistry · doi:10.1007/s00216-009-2634-y · Cited by 79 · see citing works

Physiologically Based Absorption Modeling to Explore the Impact of Food and Gastric pH Changes on the Pharmacokinetics of Alectinib

Parrott, N. J., Yu, L. J., Takano, R., Nakamura, M., & Morcos, P. N. (2016) · The AAPS Journal · doi:10.1208/s12248-016-9957-3 · Cited by 77 · see citing works

Optimized conditions for MDCK permeability and turbidimetric solubility studies using compounds representative of BCS classes I–IV

Taub, M. E., Kristensen, L. L., & Frøkjær, S. (2002) · European Journal of Pharmaceutical Sciences · doi:10.1016/s0928-0987(02)00015-5 · Cited by 77 · see citing works

Impact of Gut Microbiota-Mediated Bile Acid Metabolism on the Solubilization Capacity of Bile Salt Micelles and Drug Solubility

Enright, E. F., Joyce, S. A., Gahan, C. G. M., & Griffin, B. T. (2017) · Molecular Pharmaceutics · doi:10.1021/acs.molpharmaceut.6b01155 · Cited by 77 · see citing works

Incorporation of Lipophilic Drugs in Sugar Glasses by Lyophilization using a Mixture of Water and Tertiary Butyl Alcohol as Solvent

van Drooge, D. J., Hinrichs, W. L. J., & Frijlink, H. W. (2004) · Journal of Pharmaceutical Sciences · doi:10.1002/jps.10590 · Cited by 77 · see citing works

Application of PBPK modeling to predict human intestinal metabolism of CYP3A substrates – An evaluation and case study using GastroPlus™

Heikkinen, A. T., Baneyx, G., Caruso, A., & Parrott, N. (2012) · European Journal of Pharmaceutical Sciences · doi:10.1016/j.ejps.2012.06.013 · Cited by 76 · see citing works

Challenges and innovations of drug delivery in older age

Khan, M. S., & Roberts, M. (2018) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2018.09.003 · Cited by 68 · see citing works

Studies on Surfactants, Cosurfactants, and Oils for Prospective Use in Formulation of Ketorolac Tromethamine Ophthalmic Nanoemulsions

Smail, S. S., Ghareeb, M. M., Omer, H. K., Al-Kinani, A. A., & Alany, R. G. (2021) · Pharmaceutics · doi:10.3390/pharmaceutics13040467 · Cited by 76 · see citing works

Solubilization and Interaction Studies of Bile Salts with Surfactants and Drugs: a Review

Malik, N. A. (2016) · Applied Biochemistry and Biotechnology · doi:10.1007/s12010-016-1987-x · Cited by 76 · see citing works

Recent Advances of Ocular Drug Delivery Systems: Prominence of Ocular Implants for Chronic Eye Diseases

Mostafa, M., Fatease, A. M. A., Alany, R. G., & Abdelkader, H. (2023) · Pharmaceutics · doi:10.3390/pharmaceutics15061746 · Cited by 75 · see citing works

Disease, destination, dose and delivery aspects of ciclosporin: the state of the art

Italia, J. L., Bhardwaj, V., & Kumar, M. N. V. R. (2006) · Drug Discovery Today · doi:10.1016/j.drudis.2006.07.015 · Cited by 74 · see citing works

Mechanistic investigation of the negative food effect of modified release zolpidem

Andreas, C. J., Pepin, X. J. H., Markopoulos, C., Vertzoni, M., Reppas, C. I., & Dressman, J. (2017) · European Journal of Pharmaceutical Sciences · doi:10.1016/j.ejps.2017.03.011 · Cited by 74 · see citing works

Febrifugine analogues as Leishmania donovani trypanothione reductase inhibitors: binding energy analysis assisted by molecular docking, ADMET and molecular dynamics simulation

Pandey, R. K., Kumbhar, B. V., Srivastava, S., Malik, R., Sundar, S., Kunwar, A., & Prajapati, V. K. (2016) · Journal of Biomolecular Structure and Dynamics · doi:10.1080/07391102.2015.1135298 · Cited by 73 · see citing works

Effect of Ionic Strength on the Binding of α-Chymotrypsin to Nanoparticle Receptors

Verma, A., Simard, J. M., & Rotello, V. M. (2004) · Langmuir · doi:10.1021/la036183v · Cited by 73 · see citing works

Fraction of a dose absorbed estimation for structurally diverse low solubility compounds

Sugano, K. (2010) · International Journal of Pharmaceutics · doi:10.1016/j.ijpharm.2010.11.049 · Cited by 72 · see citing works

Aqueous Solubility Prediction Based on Weighted Atom Type Counts and Solvent Accessible Surface Areas

Wang, J., Hou, T., & Xu, X. (2009) · Journal of Chemical Information and Modeling · doi:10.1021/ci800406y · Cited by 71 · see citing works

The effect of α-tocopherol on the in vitro solubilisation of lipophilic drugs

Nielsen, P. B., Müllertz, A., Norling, T., & Kristensen, H. G. (2001) · International Journal of Pharmaceutics · doi:10.1016/s0378-5173(01)00701-3 · Cited by 71 · see citing works

Bioavailability of amiodarone tablets administered with and without food in healthy subjects

Xu, M. J., Mojaverian, P., Doedée, M., Lin, E. T., Weinryb, I., Chiang, S. T., & Kowey, P. R. (2001) · The American Journal of Cardiology · doi:10.1016/s0002-9149(00)01396-5 · Cited by 71 · see citing works

Orally Delivered Salmon Calcitonin-Loaded Solid Lipid Nanoparticles Prepared by Micelle–Double Emulsion Method Via The Combined Use of Different Solid Lipids

Chen, C., Fan, T., Jin, Y., Zhou, Z., Yang, Y., Zhu, X. D., Zhang, Z., Zhang, Q., & Huang, Y. (2012) · Nanomedicine · doi:10.2217/nnm.12.141 · Cited by 70 · see citing works

Statistical investigation of simulated intestinal fluid composition on the equilibrium solubility of biopharmaceutics classification system class II drugs

Khadra, I., Zhou, Z., Dunn, C., WILSON, C. G., & Halbert, G. (2014) · European Journal of Pharmaceutical Sciences · doi:10.1016/j.ejps.2014.10.019 · Cited by 70 · see citing works

Colloidal Structures in Media Simulating Intestinal Fed State Conditions with and Without Lipolysis Products

Fatouros, D. G., Walrand, I., Bergenståhl, B., & Müllertz, A. (2008) · Pharmaceutical Research · doi:10.1007/s11095-008-9750-9 · Cited by 69 · see citing works

Improvement of Dissolution and Oral Absorption of ER-34122, A Poorly Water-Soluble Dual 5-Lipoxygenase/Cyclooxygenase Inhibitor With Anti-Inflammatory Activity by Preparing Solid Dispersion

Kushida, I., Ichikawa, M., & Asakawa, N. (2002) · Journal of Pharmaceutical Sciences · doi:10.1002/jps.10020 · Cited by 69 · see citing works

In Vitro–In Vivo Correlation of Efavirenz Tablets Using GastroPlus®

Honório, T. D. S., Pinto, E. C., Rocha, H. V. A., Esteves, V. S. D., dos Santos, T. C., Castro, H. C., Rodrigues, C. R., de Sousa, V. P., & Cabral, L. M. (2013) · AAPS PharmSciTech · doi:10.1208/s12249-013-0016-4 · Cited by 68 · see citing works

Evaluation of the GastroPlus™ Advanced Compartmental and Transit (ACAT) Model in Early Discovery

Gobeau, N., Stringer, R., De Buck, S., Tuntland, T., & Faller, B. (2016) · Pharmaceutical Research · doi:10.1007/s11095-016-1951-z · Cited by 67 · see citing works

Characterization of Prototype Self-Nanoemulsifying Formulations of Lipophilic Compounds

Nielsen, F. S., Gibault, E., Ljusberg‐Wahren, H., Arleth, L., Pedersen, J. S., & Müllertz, A. (2007) · Journal of Pharmaceutical Sciences · doi:10.1002/jps.20673 · Cited by 67 · see citing works

Prediction of aqueous intrinsic solubility of druglike molecules using Random Forest regression trained with Wiki-pS0 database

Avdeef, A. (2020) · ADMET & DMPK · doi:10.5599/admet.766 · Cited by 67 · see citing works

Physiologically Based Predictions of the Impact of Inhibition of Intestinal and Hepatic Metabolism on Human Pharmacokinetics of CYP3A Substrates

Fenneteau, F., Poulin, P., & Nekka, F. (2009) · Journal of Pharmaceutical Sciences · doi:10.1002/jps.21802 · Cited by 66 · see citing works

Is the full potential of the biopharmaceutics classification system reached?

Bergström, C. A. S., Andersson, S. B. E., Fagerberg, J. H., Ragnarsson, G., & Lindahl, A. H. (2013) · European Journal of Pharmaceutical Sciences · doi:10.1016/j.ejps.2013.09.010 · Cited by 64 · see citing works

Hydrotropic polymer micelles as versatile vehicles for delivery of poorly water-soluble drugs

Kim, J. Y., Kim, S., Pinal, R., & Park, K. (2011) · Journal of Controlled Release · doi:10.1016/j.jconrel.2011.02.014 · Cited by 63 · see citing works

Use of Simulated Intestinal Fluids with Caco-2 Cells and Rat Ileum

Patel, N., Forbes, B., Eskola, S. M., & Murray, J. M. (2006) · Drug Development and Industrial Pharmacy · doi:10.1080/03639040500465991 · Cited by 63 · see citing works

Examination of the Solubilization of Drugs by Bile Salt Micelles

Wiedmann, T. S., & Kamel, L. (2002) · Journal of Pharmaceutical Sciences · doi:10.1002/jps.10158 · Cited by 169 · see citing works

Solubilization of Drugs by Physiological Mixtures of Bile Salts

Wiedmann, T. S., Liang, W. F., & Kamel, L. (2002) · Pharmaceutical Research · doi:10.1023/a:1019858428449 · Cited by 60 · see citing works

Evaluating the Impact of Intestinal Bile Salts on Drug Absorption Using PBPK Modeling: Case Studies With Efavirenz, Cinnarizine, and Posaconazole

Santos, L. G. A.-A., Polak, S., & Yeo, K. R. (2026) · CPT Pharmacometrics & Systems Pharmacology · doi:10.1002/psp4.70177 · Cited by 3 · see citing works

The Use of Bile Salt Micelles for the Prediction of Human Intestinal Absorption

Waters, L. J., Shokry, D. S., Parkes, G. M. B., & Mitchell, J. C. (2016) · Journal of Pharmaceutical Sciences · doi:10.1016/j.xphs.2016.09.007 · Cited by 6 · see citing works

Solubilizing Properties of Bile Salt Solutions II.

Bates, T. R., Gibaldi, M., & Kanig, J. L. (1966) · Journal of Pharmaceutical Sciences · doi:10.1002/jps.2600550906 · Cited by 73 · see citing works