Production of artemisinin by hairy root cultures of Artemisia annua L
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The yield of artemisinin in hairy roots is relatively low.
“the yield of artemisinin in hairy roots, which is relatively low [43,44]”
From Relative expression of genes of terpene metabolism in different tissues of Artemisia annuaL (2011) · cites this paper as [43]
Cites
A Revised Medium for Rapid Growth and Bio Assays with Tobacco Tissue Cultures
Murashige, T., & Skoog, F. K. (1962) · Physiologia Plantarum · doi:10.1111/j.1399-3054.1962.tb08052.x · Cited by 67,420 · see citing works
Qinghaosu (Artemisinin): an Antimalarial Drug from China
Klayman, D. L. (1985) · Science · doi:10.1126/science.3887571 · Cited by 2,186 · see citing works
Luo, X., & Shen, C. (1987) · Medicinal Research Reviews · doi:10.1002/med.2610070103 · Cited by 320 · see citing works
Tissue cultures of Artemisia annua: Organogenesis and artemisinin production
Fulzele, D. P., Sipahimalani, A. T., & Heble, M. R. (1991) · Phytotherapy Research · doi:10.1002/ptr.2650050402 · Cited by 67 · see citing works
Ultrastructural changes of parenchyma cells in detached garlic scape during storage
Wang, Y., Chenghou, L., & Shi-jie, Y. (1994) · Europe PMC (PubMed Central) · Cited by 13 · see citing works
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Artemisinin: current state and perspectives for biotechnological production of an antimalarial drug
Liu, C., Zhao, Y., & Wang, Y. (2006) · Applied Microbiology and Biotechnology · doi:10.1007/s00253-006-0452-0 · Cited by 158 · see citing works
Self-citationRelative expression of genes of terpene metabolism in different tissues of Artemisia annuaL
Olofsson, L., Engström, A., Lundgren, A., & Brodelius, P. E. (2011) · BMC Plant Biology · doi:10.1186/1471-2229-11-45 · Cited by 144 · see citing works
The effect of phytohormones on growth and artemisinin production in Artemisia annua hairy roots
Weathers, P. J., Bunk, G., & McCoy, M. C. (2005) · In Vitro Cellular & Developmental Biology - Plant · doi:10.1079/ivp2004604 · Cited by 129 · see citing works
Molecular Farming in Artemisia annua, a Promising Approach to Improve Anti-malarial Drug Production
Pulice, G., Pelaz, S., & Matías-Hernández, L. (2016) · Frontiers in Plant Science · doi:10.3389/fpls.2016.00329 · Cited by 53 · see citing works
Feng, L.-L., Yang, R.-Y., Yang, X.-Q., Zeng, X.-M., Lu, W.-J., & Zeng, Q.-P. (2009) · Plant Science · doi:10.1016/j.plantsci.2009.03.014 · Cited by 39 · see citing works
The improvement of amorpha-4,11-diene production by a yeast-conform variant
Jiang-Qiang, K., Wei, W., Li-Na, W., Xiao-Dong, Z., Ke-Di, C., & Ping, Z. (2009) · Journal of Applied Microbiology · doi:10.1111/j.1365-2672.2008.04063.x · Cited by 22 · see citing works
Chemistry, biosynthesis and biological activity of artemisinin and related natural peroxides
Rydén, A.-M., & Kayser, O. (2007) · Topics in Heterocyclic Chemistry · doi:10.1007/7081_2007_085 · Cited by 16 · see citing works
- Authors
- Liu, C. Z., Wang, Y. C., Ouyang, F., Ye, H. C., & Li, G. F.
- Affiliations
- Chinese Academy of Sciences (CN)
- ORCID
- Venue
- Biotechnology Letters
- Published
- 1997-09
- Volume
- 19
- Issue
- 9
- Pages
- 927-929
- ISSN
- 0141-5492 (ISSN-L)
- 1573-6776
- OpenAlex
- W2066899459
- Cited by
- 94
- References
- 5
- Citations by year
- 2025: 3 · 2024: 3 · 2023: 2 · 2022: 3 · 2021: 1 · 2020: 4 · 2019: 2 · 2018: 2 · 2017: 7 · 2016: 4 · 2015: 3 · 2014: 8 · 2013: 5 · 2012: 4
- FWCI
- 1.06
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- Locations
- Biotechnology Letters (publishedVersion)
- Institute of Process Engineering, CAS Institutional Repository (submittedVersion)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Plant tissue culture and regeneration
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Plant biochemistry and biosynthesis
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Biotechnology › Biochemical and biochemical processes
- Keywords
- artemisinin production, Artemisia annua, hairy root culture, Aspergillus oryzae, elicitation, gibberellic acid, nitrogen source ratio, culture medium optimization, secondary metabolite biosynthesis
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Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
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