Chemistry, biosynthesis and biological activity of artemisinin and related natural peroxides
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Terpene biosynthesis and its regulation in A. annua have been well reviewed, including the central role of amorpha-4,11-diene (451) in artemisinin biosynthesis and the likelihood that glandular trichomes are the location of artemisinin biosynthesis.
“Terpene biosynthesis [271,272,273,274,275,276] and its regulation [277,278] in A. annua have been well reviewed, including the central role of amorpha-4,11-diene (451) in the biosynthesis of artemisinin (495) [279] and the likelihood that glandular trichomes are the location wherein artemisinin biosynthesis actually occurs [244,280]”
From The Biosynthesis of Artemisinin (Qinghaosu) and the Phytochemistry of Artemisia annua L. (Qinghao) (2010) · cites this paper as [272]
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The Biosynthesis of Artemisinin (Qinghaosu) and the Phytochemistry of Artemisia annua L. (Qinghao)
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- Authors
- Rydén, A.-M., & Kayser, O.
- Affiliations
- University of Groningen (NL)
- Corresponding author
- Kayser, Oliver
- ORCID
- Kayser, Oliver
- Venue
- Topics in Heterocyclic Chemistry
- Publisher
- Springer Berlin Heidelberg
- Published
- 2007-09-06
- Pages
- 1-31
- OpenAlex
- W40074062
- Cited by
- 16
- References
- 139
- Citations by year
- 2026: 1 · 2022: 1 · 2019: 2 · 2015: 1 · 2014: 1 · 2013: 1 · 2012: 1
- FWCI
- 3.72
- Type
- book chapter
- Language
- en
- Open access
- closed
- Locations
- Springer eBooks (publishedVersion)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Cancer Research › Sesquiterpenes and Asteraceae Studies
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Phytochemical compounds biological activities
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Malaria Research and Control
- Keywords
- artemisinin, sesquiterpenes, trioxane, antimalarial drugs, artemisinin derivatives, biosynthesis, heterologous expression, plant cell culture, pharmacokinetics, drug delivery systems, Plasmodium, bioavailability, targeted drug delivery
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