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Cited by 357Polymer Surface Interaction Studiesbiodegradable polymer synthesis and propertiesBone Tissue Engineering Materials

The DOI matches its Crossref record; 143 of the 143 references it cites were found in a registry or an index.

Effects of the Chemical Structure and the Surface Properties of Polymeric Biomaterials on Their Biocompatibility

Wang, You-Xiong, Robertson, John L., Spillman, William B., Claus, Richard O.·2004·Pharmaceutical Research
DOI 10.1023/b:pham.0000036909.41843.18
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Abstract

Polymeric biomaterials have extensively been used in medicinal applications. However, factors that determine their biocompatibility are still not very clear. This article reviews various effects of the chemical structure and the surface properties of polymeric biomaterials on their biocompatibility, including protein adsorption, cell adhesion, cytotoxicity, blood compatibility, and tissue compatibility. Understanding these aspects of biocompatibility is important to the improvement of the biocompatibility of existing polymers and the design of new biocompatible polymers.

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Crossref · 10.1023/b:pham.0000036909.41843.18

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143 of 143 references verified0 citation errors · 0 not checkable

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  • These results were supposed to be affected by different mechanical loading by surface roughness, and besides chemical composition, also by resulting surface properties such as hydrophobicity, which are main predictors of protein adsorption and cell adhesion.

    “These results were supposed to be affected by different mechanical loading by the surface roughness, and besides the chemical composition of the material surface, also by the resulting surface properties, often expressed in terms of hydrophobicity, that are the main predictors of protein adsorption and, thus, cell adhesion [77-79].”

    From Shape-memory polymers as a technology platform for biomedical applications (2010) · cites this paper as [79]

Citations

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  8. K. Ishihara, N. Shibata, and S. Tanaka. Y Iwasaki, T. Kurosaki, and N. Nakabayashi. Improved blood compatibility of segmented polyurethanes by polymeric additives having phospholipid polar group. II. Dispersion state of polymeric additive and protein adsorption on the surface. J. Biomed. Mater. { vn32}:401–408 (1996). · DOI
  9. P. Ferruti, S. Knobloch, E. Ranucci, E. Gianasi, and R. Duncan. A novel chemical modification of poly-L-lysine reducing toxicity while preserving cationic properties. Proc. Int. Symp. Control. Rel. Bioact. Mater. { vn24}:45–46 (1997).
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Metadata

Authors
Wang, Y.-X., Robertson, J. L., Spillman, W. B., & Claus, R. O.
Affiliations
  • Virginia Tech (US)
  • Virginia–Maryland College of Veterinary Medicine (US)
Corresponding author
Wang, You-Xiong
ORCID
Robertson, John L.
Venue
Pharmaceutical Research
Publisher
Springer Science and Business Media LLC
Published
2004-08
Volume
21
Issue
8
Pages
1362-1373
ISSN
  • 0724-8741 (ISSN-L)
  • 1573-904X
DOI
10.1023/b:pham.0000036909.41843.18
OpenAlex
W2113455936
Cited by
357
References
143
Citations by year
2025: 8 · 2024: 8 · 2023: 10 · 2022: 11 · 2021: 21 · 2020: 17 · 2019: 17 · 2018: 19 · 2017: 18 · 2016: 28 · 2015: 21 · 2014: 24 · 2013: 24 · 2012: 21
FWCI
0.64
Type
journal article
Language
en
Open access
closed
Licence
Locations
  • Pharmaceutical Research (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Physical Sciences › Materials Science › Surfaces, Coatings and Films › Polymer Surface Interaction Studies
  • Physical Sciences › Materials Science › Biomaterials › biodegradable polymer synthesis and properties
  • Physical Sciences › Engineering › Biomedical Engineering › Bone Tissue Engineering Materials
Keywords
polymeric biomaterials, biocompatibility, molecular structure, surface properties, protein adsorption, cell adhesion, cytotoxicity, hemocompatibility, histocompatibility
MeSH terms
Animals, Biocompatible Materials, Humans, Materials Testing, Molecular Conformation, Molecular Weight, Polymers, Surface Properties, Molecular Structure, Hydrophobic and Hydrophilic Interactions

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