Cited by 551Psychotherapy Techniques and ApplicationsAnxiety, Depression, Psychometrics, Treatment, Cognitive ProcessesTreatment of Major Depression

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Reducing relapse and recurrence in unipolar depression: a comparative meta-analysis of cognitive-behavioral therapy’s effects

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Vittengl, Jeffrey R., Clark, Lee Anna, Dunn, Todd W., Jarrett, Robin B.·2007·Journal of Consulting and Clinical Psychology

DOI 10.1037/0022-006x.75.3.475PMC PMC2630051

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Abstract

Relapse and recurrence following response to acute-phase treatment for major depressive disorder (MDD) are prevalent and costly. In a meta-analysis of 28 studies including 1,880 adults, the authors reviewed the world's published literature on cognitive-behavioral therapies (CT) aimed at preventing relapse-recurrence in MDD. Results indicate that after discontinuation of acute-phase treatment, many responders to CT relapse-recur (29% within 1 year and 54% within 2 years). These rates appear comparable to those associated with other depression-specific psychotherapies but lower than those associated with pharmacotherapy. Among acute-phase treatment responders, continuation-phase CT reduced relapse-recurrence compared with assessment only at the end of continuation treatment (21% reduction) and at follow-up (29% reduction). Continuation-phase CT also reduced relapse-recurrence compared with other active continuation treatments at the end of continuation treatment (12% reduction) and at follow-up (14% reduction). The authors discuss implications for research and patient care and suggest directions, with methodological refinements, for future studies.

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"Depresión": Imprecisión diagnóstica y terapéutica. Importantes consecuencias en la práctica clínica
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“For long-term treatment, cognitive behavioral therapy and interpersonal psychotherapy were shown to have lasting benefits after treatment terminated (Dobson et al. 2008; Frank et al. 2007; Vittengl et al. 2007).”
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Publieke geestelijke gezondheid:analyse en synthese
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“Meta-analyses show that C-CT for depression has preventive effects greater than treatment-as-usual and non-active controls, and equal to or greater than active medication (Vittengl et al. 2007; Biesheuvel-Leliefeld et al. 2015).”
BackgroundSelf-citation
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“Meta-analysis of pooled data of published trials indicates that CBT may also contribute to decreasing the risk of relapse over 12–24 months, suggesting that its benefits might extend beyond the acute phase of treatment.(19)”
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“However, various studies have found significant rates of insufficient treatment response or non-response, relapse, and disease recurrence (Beshai et al., 2011; Casacalenda et al., 2002; H ¨ arter et al., 2004; Taylor et al., 2010; Vittengl et al., 2007).”
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Leveraging Adaptive Sessions Based on Therapeutic Empathy Through a Virtual Agent
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Identifying relapse prevention elements during psychological treatment of depression: Development of an observer-based rating instrument
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“Psychotherapy research on the effective prevention of relapse and recurrence after acute depression treatments has mostly investigated cognitive behavioral interventions, both alone and in combination with antidepressants (Bockting et al., 2005; Vittengl et al., 2007; Jarrett et al., 2013).”
Background
Supported self-help to prevent relapse or recurrence of depression: Who benefits most?
Dijkstra‐Kersten, S. M. A., Biesheuvel-Leliefeld, K. E. M., van der Wouden, J. C., van Schaik, A., Bosmans, J. E., van Marwijk, H., & van der Horst, H. E. (2019) · Journal of Affective Disorders · doi:10.1016/j.jad.2019.07.006 · Cited by 4
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“는 연구가 효과가 더 큰 것으로 나타난 선행연구의 결과 와 비슷한 경향을 보이고 있었다[27].”
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Background

Authors: Vittengl, J. R., Clark, L. A., Dunn, T. W., & Jarrett, R. B.
Affiliations: Truman State University (US)
University of Iowa (US)
The University of Texas Southwestern Medical Center (US)
ORCID: Vittengl, Jeffrey R.
Clark, Lee Anna
Jarrett, Robin B.
Venue: Journal of Consulting and Clinical Psychology
Publisher: American Psychological Association (APA)
Published: 2007
Volume: 75
Issue: 3
Pages: 475-488
ISSN: 0022-006X (ISSN-L)
1939-2117
DOI: 10.1037/0022-006x.75.3.475
PMC: PMC2630051
OpenAlex: W1981386178
Cited by: 551
References: 102
Citations by year: 2026: 11 · 2025: 15 · 2024: 24 · 2023: 19 · 2022: 22 · 2021: 30 · 2020: 34 · 2019: 42 · 2018: 35 · 2017: 32 · 2016: 36 · 2015: 36 · 2014: 38 · 2013: 29 · 2012: 37
FWCI: 4.36
Type: journal article
Language: en
Open access: green
www.ncbi.nlm.nih.gov
Locations: Journal of Consulting and Clinical Psychology (publishedVersion)
PubMed (publishedVersion)
PubMed Central (acceptedVersion)
Funders: National Institute of Mental Health (MH-58397; MH-01571)
Topics: Social Sciences › Psychology › Clinical Psychology › Psychotherapy Techniques and Applications
Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
Health Sciences › Medicine › Pharmacology (medical) › Treatment of Major Depression
Keywords: major depressive disorder, relapse prevention, recurrence prevention, cognitive behavioral therapy, acute phase treatment, psychotherapy versus pharmacotherapy, treatment discontinuation
MeSH terms: Depressive Disorder, Humans, Recurrence, Cognitive Behavioral Therapy

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Reducing relapse and recurrence in unipolar depression: a comparative meta-analysis of cognitive-behavioral therapy’s effects

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