Cited by 551Psychotherapy Techniques and ApplicationsAnxiety, Depression, Psychometrics, Treatment, Cognitive ProcessesTreatment of Major Depression

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Reducing relapse and recurrence in unipolar depression: a comparative meta-analysis of cognitive-behavioral therapy’s effects

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Vittengl, Jeffrey R., Clark, Lee Anna, Dunn, Todd W., Jarrett, Robin B.·2007·Journal of Consulting and Clinical Psychology

DOI 10.1037/0022-006x.75.3.475PMC PMC2630051

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Abstract

Relapse and recurrence following response to acute-phase treatment for major depressive disorder (MDD) are prevalent and costly. In a meta-analysis of 28 studies including 1,880 adults, the authors reviewed the world's published literature on cognitive-behavioral therapies (CT) aimed at preventing relapse-recurrence in MDD. Results indicate that after discontinuation of acute-phase treatment, many responders to CT relapse-recur (29% within 1 year and 54% within 2 years). These rates appear comparable to those associated with other depression-specific psychotherapies but lower than those associated with pharmacotherapy. Among acute-phase treatment responders, continuation-phase CT reduced relapse-recurrence compared with assessment only at the end of continuation treatment (21% reduction) and at follow-up (29% reduction). Continuation-phase CT also reduced relapse-recurrence compared with other active continuation treatments at the end of continuation treatment (12% reduction) and at follow-up (14% reduction). The authors discuss implications for research and patient care and suggest directions, with methodological refinements, for future studies.

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Diagnostic and Statistical Manual of Mental Disorders
Williams, J. B. W., & First, M. B. (2013) · Oxford University Press eBooks · doi:10.1093/acrefore/9780199975839.013.104 · Cited by 109,845
An inventory for measuring depression
BECK, A. T. (1961) · Archives of General Psychiatry · doi:10.1001/archpsyc.1961.01710120031004 · Cited by 38,032
A rating scale for depression
Hamilton, M. (1960) · Journal of Neurology, Neurosurgery & Psychiatry · doi:10.1136/jnnp.23.1.56 · Cited by 32,817
Applied Multiple Regression/Correlation Analysis for the Behavioral Sciences
Cohen, P., Cohen, P., West, S. G., & Aiken, L. S. (2014) · Psychology Press eBooks · doi:10.4324/9781410606266 · Cited by 20,870
Lifetime Prevalence and Age-of-Onset Distributions of DSM-IV Disorders in the National Comorbidity Survey Replication
Kessler, R. C., Berglund, P., Demler, O., Jin, R., Merikangas, K. R., & Walters, E. E. (2005) · Archives of General Psychiatry · doi:10.1001/archpsyc.62.6.593 · Cited by 20,391
Development and validation of a geriatric depression screening scale: a preliminary report
Yesavage, J. A., Brink, T. L., Rose, T. L., Lum, O., Huang, V., Adey, M., & Leirer, V. O. (1982) · Journal of Psychiatric Research · doi:10.1016/0022-3956(82)90033-4 · Cited by 15,025
Untitled work
(2000) · Cited by 9,198
The Epidemiology of Major Depressive Disorder: Results From the National Comorbidity Survey Replication (NCS-R)
Kessler, R. C., Berglund, P., Demler, O., Jin, R., Koretz, D., Merikangas, K. R., Rush, A. J., Walters, E. E., & Wang, P. S. (2003) · JAMA · doi:10.1001/jama.289.23.3095 · Cited by 7,988
Selective Cortical Undercutting As a Means of Modifying and Studying Frontal Lobe Function in Man
Scoville, W. B. (1949) · Journal of neurosurgery · doi:10.3171/jns.1949.6.1.0065 · Cited by 7,374
Untitled work
(1996) · Cited by 6,884

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Alsayednasser, B., Widnall, E., O’Mahen, H., Wright, K. A., Warren, F. C., Ladwa, A., Khazanov, G. K., Byford, S., Kuyken, W., Watkins, E. R., et al. (2022) · Behaviour Research and Therapy · doi:10.1016/j.brat.2022.104185 · Cited by 70
Long-term outcomes of psychological interventions on children and young people’s mental health: A systematic review and meta-analysis
Pilling, S., Fonagy, P., Allison, E., Barnett, P., Campbell, C., Constantinou, M., Gardner, T., Lorenzini, N., Matthews, H., Ryan, A., et al. (2020) · PLoS ONE · doi:10.1371/journal.pone.0236525 · Cited by 61
“depression [31]) show a relapsing and remitting course which is evident at 12-month follow-up.”
Background
Eye movement desensitization and reprocessing for depression: a systematic review and meta-analysis
Carletto, S., Malandrone, F., Berchialla, P., Oliva, F., Colombi, N., Hase, M., Hofmann, A., & Ostacoli, L. (2021) · European Journal of Psychotraumatology · doi:10.1080/20008198.2021.1894736 · Cited by 66
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Gauhar, Y. W. M. (2016) · Journal of EMDR Practice and Research · doi:10.1891/1933-3196.10.2.59 · Cited by 58
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Lower cortisol levels predict recurrence in remitted patients with recurrent depression: A 5.5 year prospective study
Bockting, C. L. H., Lok, A., Visser, I., Assies, J., Koeter, M. W., & Schene, A. H. (2012) · Psychiatry Research · doi:10.1016/j.psychres.2012.03.044 · Cited by 57
“Furthermore, stress reducing cognitive therapy (CT) has a benificial effect in preventing recurrence (Bockting et al., 2005, 2009; Vittengl et al., 2007; Guidi et al., 2011).”
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Huberty, T. J. (2012) · Springer eBooks · doi:10.1007/978-1-4614-3110-7 · Cited by 56
Metacognitive therapy versus cognitive behaviour therapy in adults with major depression: a parallel single-blind randomised trial
Callesen, P., Reeves, D., Heal, C., & Wells, A. (2020) · Scientific Reports · doi:10.1038/s41598-020-64577-1 · Cited by 55
e-CBT (myCompass), Antidepressant Medication, and Face-to-Face Psychological Treatment for Depression in Australia: A Cost-Effectiveness Comparison
Solomon, D., Proudfoot, J., Clarke, J., & Christensen, H. (2015) · Journal of Medical Internet Research · doi:10.2196/jmir.4207 · Cited by 55
“[31] Meta-analysis of CBT clinical trials Beta (146, 115) 0.”
Long‐term effect of combined interpersonal psychotherapy and pharmacotherapy in a randomized trial of depressed patients
Zobel, I., Kech, S., van Calker, D., Dykierek, P., Berger, T., Schneibel, R., & Schramm, E. (2011) · Acta Psychiatrica Scandinavica · doi:10.1111/j.1600-0447.2010.01671.x · Cited by 54
“Overall, these studies demonstrated a moderate effect of combined treatment resulting in reduced relapse rates when compared to medication alone (12, 13).”
BackgroundResult
Mood reactivity rather than cognitive reactivity is predictive of depressive relapse: A randomized study with 5.5-year follow-up.
van Rijsbergen, G. D., Bockting, C., Burger, H., Spinhoven, P., Koeter, M. W. J., Ruhé, H. G., Hollon, S. D., & Schene, A. H. (2013) · Journal of Consulting and Clinical Psychology · doi:10.1037/a0032223 · Cited by 56
Deterioration in psychosocial functioning predicts relapse/recurrence after cognitive therapy for depression
Vittengl, J. R., Clark, L. A., & Jarrett, R. B. (2008) · Journal of Affective Disorders · doi:10.1016/j.jad.2008.04.004 · Cited by 55
“Continuation CT (C-CT) reduces major depressive relapse/recurrence substantially (Vittengl et al., 2007), but associations between psychosocial functioning and depressive symptoms during this treatment are unknown.”
BackgroundInfluentialSelf-citation
Cognitive therapy for anxious depression in STAR(*) D: what have we learned?
Farabaugh, A., Alpert, J., Wisniewski, S. R., Otto, M. W., Fava, M., Baer, L., Perlis, R., Friedman, E., Nyer, M., Bitran, S., et al. (2012) · Journal of Affective Disorders · doi:10.1016/j.jad.2012.04.029 · Cited by 52
Innovative ICT Solutions to Improve Treatment Outcomes for Depression: The ICT4Depression Project
Warmerdam, L., Riper, H. M., Michel, K., Pepijn, V. D. V., Rocha, A., Mario, R. H., Tousset, E., Hugo, S., Andersson, G., & Cuijpers, P. J. (2012) · Studies in health technology and informatics · doi:10.3233/978-1-61499-121-2-339 · Cited by 54
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Cognitive Behavioral Therapy for Depression
Sudak, D. M. (2011) · Psychiatric Clinics of North America · doi:10.1016/j.psc.2011.10.001 · Cited by 53
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Evidence-Based Applications of Combination Psychotherapy and Pharmacotherapy for Depression
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Cox, G. R., Fisher, C. A., De Silva, S., Phelan, M., Akinwale, O. P., Simmons, M. B., & Hetrick, S. E. (2012) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd007504.pub2 · Cited by 48
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Harkness, K. L., Theriault, J. E., Stewart, J. G., & Bagby, R. M. (2013) · Depression and Anxiety · doi:10.1002/da.22177 · Cited by 45
Preliminary clinical and cost effectiveness of augmented depression therapy versus cognitive behavioural therapy for the treatment of anhedonic depression (ADepT): a single-centre, open-label, parallel-group, pilot, randomised, controlled trial
Dunn, B. D., Widnall, E., Warbrick, L. A., Warner, F. R., Reed, N., Price, A., Kock, M., Courboin, C., Stevens, R., Wright, K. A., et al. (2023) · EClinicalMedicine · doi:10.1016/j.eclinm.2023.102084 · Cited by 50
“3 Change during current psycho-therapeutic and drug treatment is clinically signi ﬁ cant but sub-optimal (50% of patients remit, 50% of whom relapse within two-years, meaning a sustained recovery rate of around 25% 4,5 ).”
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Background
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“The aim of this study was to determine whether the add-on of a Web-based self-help program to multimodal inpatient treatment of depressed patients also improves stability of remission and test postulated predictors of residual depression [29] at follow-up based on patient characteristics.”
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Learning cognitive behavior therapy
Gumport, N. B., Williams, J. J., & Harvey, A. G. (2015) · Journal of Behavior Therapy and Experimental Psychiatry · doi:10.1016/j.jbtep.2015.03.015 · Cited by 40
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Background
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Brouwer, M. E., Williams, A. D., Kennis, M., Fu, Z., Klein, N. S., Cuijpers, P., & Bockting, C. L. H. (2019) · Clinical Psychology Review · doi:10.1016/j.cpr.2019.101773 · Cited by 39
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Hase, M., Plagge, J., Hase, A., Braas, R., Ostacoli, L., Hofmann, A., & Huchzermeier, C. (2018) · Frontiers in Psychology · doi:10.3389/fpsyg.2018.01384 · Cited by 41
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Background
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Background
Use of auxiliary psychiatric treatment during a 5-year follow-up among patients receiving short- or long-term psychotherapy
Knekt, P., Lindfors, O., Renlund, C., Sares‐Jäske, L., Laaksonen, M. A., & Virtala, E. T. (2011) · Journal of Affective Disorders · doi:10.1016/j.jad.2011.07.024 · Cited by 38
“Insufficiency of short-term therapies for treatment of depression, expressed by the need and realization of additional treatment has also been a repeated finding in cognitive (Beck et al., 1985; Vittengl et al., 2007) and interpersonal (Frank et al.”
Background
The Effects of Cognitive Therapy versus ‘No Intervention’ for Major Depressive Disorder
Jakobsen, J. C., Hansen, J. L., Storebø, O. J., Simonsen, E. H., & Gluud, C. N. (2011) · PLoS ONE · doi:10.1371/journal.pone.0028299 · Cited by 41
Predictive modeling in e-mental health: A common language framework
Becker, D., van Breda, W., Funk, B., Hoogendoorn, M., Ruwaard, J., & Riper, H. M. (2018) · Internet Interventions · doi:10.1016/j.invent.2018.03.002 · Cited by 43
“The post-intervention phase can consist of follow-up screenings and additional or repeated interventions to reduce the risk of relapse (Kessler et al., 2005; Vittengl et al., 2009).”
Cost–Utility of Internet-Based Cognitive Behavioral Therapy in Unipolar Depression: A Markov Model Simulation
Baumann, M., Stargardt, T., & Frey, S. (2020) · Applied Health Economics and Health Policy · doi:10.1007/s40258-019-00551-x · Cited by 38
“[59], reviewed the literature on acute- and continuation-phase FCBT in unipolar depression and identified 28 studies.”
Background
The Three-Month Effect of Mobile Internet-Based Cognitive Therapy on the Course of Depressive Symptoms in Remitted Recurrently Depressed Patients: Results of a Randomized Controlled Trial
Kok, G. D., Burger, H., Riper, H. M., Cuijpers, P. J., Dekker, J., van Marwijk, H., Smit, F., Beck, A. T., & Bockting, C. (2015) · Psychotherapy and Psychosomatics · doi:10.1159/000369469 · Cited by 38
Clinical and cost-effectiveness of computerised cognitive behavioural therapy for depression in primary care: Design of a randomised trial
de Graaf, L. E., Gerhards, S. A. H., Evers, S., Arntz, A. R., Riper, H. M., Severens, J. L., Widdershoven, G. A. M., Metsemakers, J. F. M., & Huibers, M. J. H. (2008) · BMC Public Health · doi:10.1186/1471-2458-8-224 · Cited by 38
“Cognitive behavioural therapy (CBT) has proven to be as effective as pharmacotherapy in the acute phase of mild to severe depression, and seems even more effective in the prevention of recurrence and relapse [17-19].”
Memory support strategies and bundles: A pathway to improving cognitive therapy for depression?
Dong, L., Lee, J. Y., & Harvey, A. G. (2017) · Journal of Consulting and Clinical Psychology · doi:10.1037/ccp0000167 · Cited by 38
Longitudinal course of cognitive function across treatment in patients with MDD: A meta-analysis
Bernhardt, M., Klauke, S., & Schröder, A. (2019) · Journal of Affective Disorders · doi:10.1016/j.jad.2019.02.021 · Cited by 43
Achievement and maintenance of sustained response during the Treatment for Adolescents With Depression Study continuation and maintenance therapy.
Rohde, P., Silva, S., Tonev, S., Kennard, B., Vitiello, B., Kratochvil, C., Reinecke, M. A., Curry, J. F., Simons, A., & March, J. (2008) · Archives of General Psychiatry · doi:10.1001/archpsyc.65.4.447 · Cited by 32
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Tovote, K. A., Schroevers, M. J., Snippe, E., Sanderman, R., Links, T. P., Emmelkamp, P. M. G., & Fleer, J. (2015) · Psychotherapy and Psychosomatics · doi:10.1159/000375453 · Cited by 35
The Effects of Cognitive Therapy Versus ‘Treatment as Usual’ in Patients with Major Depressive Disorder
Jakobsen, J. C., Hansen, J. L., Storebø, O. J., Simonsen, E. H., & Gluud, C. N. (2011) · PLoS ONE · doi:10.1371/journal.pone.0022890 · Cited by 36
Publication bias in meta-analyses of the efficacy of psychotherapeutic interventions for depression.
Niemeyer, H., Musch, J., & Pietrowsky, R. (2012) · Journal of Consulting and Clinical Psychology · doi:10.1037/a0031152 · Cited by 35
Metacognitive Therapy for Depression: A 3-Year Follow-Up Study Assessing Recovery, Relapse, Work Force Participation, and Quality of Life
Solem, S., Kennair, L. E. O., Hagen, R., Havnen, A., Nordahl, H. M., Adrian Wells, A., & Hjemdal, O. (2019) · Frontiers in Psychology · doi:10.3389/fpsyg.2019.02908 · Cited by 35
Mindfulness-based cognitive therapy for depression.
Riemann, D., Hertenstein, E., & Schramm, E. (2016) · The Lancet · doi:10.1016/s0140-6736(16)00660-7 · Cited by 1,290
Design of a health-economic Markov model to assess cost-effectiveness and budget impact of the prevention and treatment of depressive disorder
Lokkerbol, J., Wijnen, B. F. M., Ruhé, H. G., Spijker, J., Morad, A., Schoevers, R. A., de Boer, M. K., Cuijpers, P. J., & Smit, F. (2020) · Expert Review of Pharmacoeconomics & Outcomes Research · doi:10.1080/14737167.2021.1844566 · Cited by 35
“1Taken from van Zoonen et al. 2014 [15]; 2 Taken from Karyotaki et al. 2017 [38]; 3 Taken from Cuijpers et al. 2019 [10]; 4 Taken from Cipriani et al. 2018 [39]; 5 Taken from Vittengl et al. 2007 [40]; 6 Taken from Biesheuvel-Leliefeld et al. 2015 [41].”
Background
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Arntz, A. R. (2019) · Journal of Behavior Therapy and Experimental Psychiatry · doi:10.1016/j.jbtep.2019.101510 · Cited by 38
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Jha, M. K., Minhajuddin, A., Greer, T. L., Carmody, T. J., Rush, A. J., & Trivedi, M. H. (2016) · PLoS ONE · doi:10.1371/journal.pone.0167901 · Cited by 35
Comparative efficacy and durability of continuation phase cognitive therapy for preventing recurrent depression: Design of a double-blinded, fluoxetine- and pill placebo-controlled, randomized trial with 2-year follow-up
Jarrett, R. B., & Thase, M. E. (2010) · Contemporary Clinical Trials · doi:10.1016/j.cct.2010.04.004 · Cited by 51
Self-citation
Enduring effects of psychotherapy, antidepressants and their combination for depression: a systematic review and meta-analysis
Voderholzer, U., Barton, B. B., Favreau, M., Zisler, E. M., Rief, W., Wilhelm, M., & Schramm, E. (2024) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2024.1415905 · Cited by 48
Incidence and predictors of relapse during continuation treatment of major depression with SSRI, interpersonal psychotherapy, or their combination
Rucci, P., Frank, E., Calugi, S., Miniati, M., Benvenuti, A., Wallace, M. L., Fagiolini, A. M., Maggi, L., Kupfer, D. J., & Cassano, G. B. (2011) · Depression and Anxiety · doi:10.1002/da.20894 · Cited by 33
Moderators of continuation phase cognitive therapy's effects on relapse, recurrence, remission, and recovery from depression
Vittengl, J. R., Clark, L. A., & Jarrett, R. B. (2010) · Behaviour Research and Therapy · doi:10.1016/j.brat.2010.01.006 · Cited by 32
“20 is roughly the average effect of continuation-phase CT versus non-active control on relapse/recurrence at the end of treatment (Vittengl et al., 2007).”
BackgroundInfluentialSelf-citation
Schema therapy versus cognitive behavioral therapy versus individual supportive therapy for depression in an inpatient and day clinic setting: study protocol of the OPTIMA-RCT
Kopf‐Beck, J., Zimmermann, P., Egli, S., Rein, M., Kappelmann, N., Fietz, J., Tamm, J., Rek, K., Lucae, S., Brem, A., et al. (2020) · BMC Psychiatry · doi:10.1186/s12888-020-02880-x · Cited by 48
Mechanisms of rumination change in adolescent depression (RuMeChange): study protocol for a randomised controlled trial of rumination-focused cognitive behavioural therapy to reduce ruminative habit and risk of depressive relapse in high-ruminating adolescents
Roberts, H., Jacobs, R. H., Bessette, K. L., Crowell, S. E., Schreiner, M. W., Thomas, L. R., Easter, R. E., Pocius, S. L., Dillahunt, A. K., Frandsen, S. B., et al. (2021) · BMC Psychiatry · doi:10.1186/s12888-021-03193-3 · Cited by 41
“A recent meta-analysis of adults reported that 29% of patients experienced relapse within 1 year and 56% experienced a recurrence within 2 years [11], with similar statistics in adolescents [12], emphasizing that for many, depression has a chronic recurrent course.”
Background
Predictors of the longitudinal course of postpartum depression following interpersonal psychotherapy.
Nylen, K. J., O’Hara, M. W., Brock, R. L., Moel, J. E., Gorman, L., & Stuart, S. P. (2010) · Journal of Consulting and Clinical Psychology · doi:10.1037/a0020623 · Cited by 32
Psychotherapy Versus Pharmacotherapy of Depression: What’s the Evidence?
Leichsenring, F., Steinert, C., & Hoyer, J. (2016) · Zeitschrift für psychosomatische Medizin und Psychotherapie · doi:10.13109/zptm.2016.62.2.190 · Cited by 33
“Psychotherapy was found to be as efficacious as pharmacotherapy in the short-term but superior in the long-term especially with regard to relapse prevention (Cuijpers et al. 2013; Dobson et al. 2008; Forand et al. 2013; Hollon et al. 2005; Imel et al. 2008; Spielmans et al. 2011; Vittengl et al. 2007).”
Background
Differential effects of state and trait mindfulness on the late positive potential.
Egan, R., Hill, K. E., & Foti, D. (2017) · Emotion · doi:10.1037/emo0000383 · Cited by 33
How much cognitive therapy, for which patients, will prevent depressive relapse?
Jarrett, R. B., Vittengl, J. R., & Clark, L. A. (2008) · Journal of Affective Disorders · doi:10.1016/j.jad.2008.02.011 · Cited by 32
“It is known that A-CT can reduce depressive relapse, even when discontinued, whereas responders to acute phase pharmacotherapy more often need continuation pharmacotherapy to avoid relapse (Vittengl et al., 2007).”
BackgroundSelf-citation
Vulnerability for new episodes in recurrent major depressive disorder: protocol for the longitudinal DELTA-neuroimaging cohort study
Mocking, R. J. T., Figueroa, C. A., Rive, M. M., Geugies, H., Servaas, M. N., Assies, J., Koeter, M. W. J., Vaz, F. M., Wichers, M., van Straalen, J. P., et al. (2016) · BMJ Open · doi:10.1136/bmjopen-2015-009510 · Cited by 32
“Below, we will ﬁ rst outline our theoretical framework to provide background for our hypotheses regarding the speci ﬁ cally selected factors that we will investigate.”
Method
Major depression treatment in Germany–descriptive analysis of health insurance fund routine data and assessment of guideline-adherence
Wiegand, H. F., Sievers, C., Schillinger, M., & Godemann, F. (2015) · Journal of Affective Disorders · doi:10.1016/j.jad.2015.09.013 · Cited by 31
Continuation-phase cognitive therapy's effects on remission and recovery from depression.
Vittengl, J. R., Clark, L. A., & Jarrett, R. B. (2009) · Journal of Consulting and Clinical Psychology · doi:10.1037/a0015238 · Cited by 31
“Discussion Previous research indicates that A-CT reduces depressive symptoms (Butler et al., 2006; Craighead et al., 2007) and C-CT reduces relapse and recurrence among A-CT responders (Vittengl et al., 2007).”
BackgroundMethodSelf-citation
Single treatments that have lasting effects: some thoughts on the antidepressant effects of ketamine and botulinum toxin and the anxiolytic effect of psilocybin
Young, S. N. (2013) · Journal of Psychiatry and Neuroscience · doi:10.1503/jpn.120128 · Cited by 31
Evaluating Augmented Depression Therapy (ADepT): study protocol for a pilot randomised controlled trial
Dunn, B. D., Widnall, E., Reed, N., Taylor, R. S., Owens, C. V., Spencer, A. E., Kraag, G., Kok, G., Geschwind, N., Wright, K. A., et al. (2019) · Pilot and Feasibility Studies · doi:10.1186/s40814-019-0438-1 · Cited by 35
Barriers to Cognitive Behavioral Therapy Homework Completion Scale–Depression Version: Development and Psychometric Evaluation
Callan, J. A., Dunbar‐Jacob, J. M., Sereika, S. M., Stone, C. A., Fasiczka, A. L., Jarrett, R. B., & Thase, M. E. (2012) · International Journal of Cognitive Therapy · doi:10.1521/ijct.2012.5.2.219 · Cited by 31
Self-citation
Do the effects of internet-delivered cognitive-behavioral therapy (i-CBT) last after a year and beyond? A meta-analysis of 154 randomized controlled trials (RCTs)
Zainal, N. H., Soh, C. P., Doren, N. V., & Benjet, C. L. (2024) · Clinical Psychology Review · doi:10.1016/j.cpr.2024.102518 · Cited by 35
Effectiveness of Supported Self-Help in Recurrent Depression: A Randomized Controlled Trial in Primary Care
Biesheuvel-Leliefeld, K. E. M., Dijkstra‐Kersten, S. M. A., van Schaik, A., van Marwijk, H., Smit, F., van der Horst, H. E., & Bockting, C. (2017) · Psychotherapy and Psychosomatics · doi:10.1159/000472260 · Cited by 32
A Systematic Review of the Combined Use of Electroconvulsive Therapy and Psychotherapy for Depression
McClintock, S. M., Brandon, A. R., Husain, M. M., & Jarrett, R. B. (2011) · Journal of Ect · doi:10.1097/yct.0b013e3181faaeca · Cited by 31
Self-citation
Disrupting the rhythm of depression: design and protocol of a randomized controlled trial on preventing relapse using brief cognitive therapy with or without antidepressants
Bockting, C., Elgersma, H. J., van Rijsbergen, G. D., de Jonge, P., Ormel, J., Buskens, E., Stant, A. D., de Jong, P. J., Peeters, F. P. M. L., Huibers, M. J. H., et al. (2011) · BMC Psychiatry · doi:10.1186/1471-244x-11-8 · Cited by 29
“There is convincing evidence, based on a recent meta-analysis [12], for the preventive effect of CT, and some evidence for specific forms of CT (like Mindfulness Based Cognitive Therapy; MBCT).”
Background
Psychological Interventions for Prevention of Depression Relapse: Systematic Review and Network Meta-Analysis
Zhou, Y., Zhao, D., Zhu, X., Liu, L., Meng, M., Shao, X., Zhu, X., Xiang, J., He, J., Zhao, Y., et al. (2022) · Translational Psychiatry · doi:10.1038/s41398-023-02604-1 · Cited by 39
“Antidepressants were found to be significantly better than CBT, it was different from the previous review [30, 45].”
Result
A systematic review and meta analysis on digital mental health interventions in inpatient settings
Diel, A., Schröter, I. C., Frewer, A.-L., Jansen, C., Robitzsch, A., Gradl-Dietsch, G., Teufel, M., & Bäuerle, A. (2024) · npj Digital Medicine · doi:10.1038/s41746-024-01252-z · Cited by 31
“Adequateaftercareenhancesrehabilitationaccordingto severalreviewsandmeta-analyses 33 – 35 .”
Exploring relapse through a network analysis of residual depression and anxiety symptoms after cognitive behavioural therapy: A proof-of-concept study
Lorimer, B., Delgadillo, J., Kellett, S., & Brown, G. P. (2019) · Psychotherapy Research · doi:10.1080/10503307.2019.1650980 · Cited by 30
“For example, a meta-analysis found that 29% of patients relapse within one year of high-intensity CBT, and this increases to 54% within two years if recurrence events are also considered (Vittengl et al., 2007).”
Result
Stop or go? Preventive cognitive therapy with guided tapering of antidepressants during pregnancy: study protocol of a pragmatic multicentre non-inferiority randomized controlled trial
Molenaar, N. M., Brouwer, M. E., Bockting, C., Bonsel, G. J., van der Veere, C. N., Torij, H. W., Hoogendijk, W. J. G., Duvekot, J. J., Burger, H., & den Berg, M. P. L. (2016) · BMC Psychiatry · doi:10.1186/s12888-016-0752-6 · Cited by 29
“This psychological intervention has proven to be effective in relapse prevention [27, 39–42].”
Interventions for preventing relapse or recurrence of depression in primary health care settings: A systematic review
Gili, M., Vicens, C., Roca, M., Andersen, P., & McMillan, D. (2014) · Preventive Medicine · doi:10.1016/j.ypmed.2014.07.035 · Cited by 28
Combined Neurofeedback and Heart Rate Variability Training for Individuals with Symptoms of Anxiety and Depression: A Retrospective Study
White, E. K., Groeneveld, K. M., Tittle, R. K., Bolhuis, N. A., Martin, R., Royer, T. G., & Fotuhi, M. (2017) · NeuroRegulation · doi:10.15540/nr.4.1.37 · Cited by 42
Preventive cognitive therapy versus care as usual in cognitive behavioral therapy responders: A randomized controlled trial.
de Jonge, M., Bockting, C., Kikkert, M., van Dijk, M. K., van Schaik, A., Peen, J., Hollon, S. D., & Dekker, J. (2019) · Journal of Consulting and Clinical Psychology · doi:10.1037/ccp0000395 · Cited by 27
Effect of specific psychotherapy for chronic depression on neural Responses to emotional faces
Klein, J. P., Becker, B., Hurlemann, R., Scheibe, C., Colla, M., & Heuser, I. (2014) · Journal of Affective Disorders · doi:10.1016/j.jad.2014.04.055 · Cited by 26
Rumination-focused cognitive behaviour therapy vs. cognitive behaviour therapy for depression: study protocol for a randomised controlled superiority trial
Hvenegaard, M., Watkins, E. R., Poulsen, S., Rosenberg, N., Gondan, M., Grafton, B., Austin, S. F., Howard, H., & Møeller, S. B. (2015) · Trials · doi:10.1186/s13063-015-0875-y · Cited by 26
“A recent metaanalysis reports relapse rates of around 29 % within 1 year and 56 % within 2 years [10].”
Facing recovery: Emotional bias in working memory, rumination, relapse, and recurrence of major depression; an experimental paradigm conducted five years after first episode of major depression
Ronold, E. H., Joormann, J., & Hammar, Å. (2019) · Applied Neuropsychology Adult · doi:10.1080/23279095.2018.1550406 · Cited by 26
Changes in quality of life following group CBT for anxiety and depression in a psychiatric outpatient clinic
Oei, T. P., & McAlinden, N. M. (2014) · Psychiatry Research · doi:10.1016/j.psychres.2014.08.036 · Cited by 33
“Empirical evidence indicates that individual and group CBT are efficacious and effective treatments for depression and anxiety (Barlow et al., 2000; Butler et al., 2006; DeRubeis and CritsChristoph, 1998; Dwyer et al., 2013; Hofmann and Smits, 2008; Oei and Dingle, 2008; Oei and Boschen, 2009; Oei et al., 1999; Stanle…”
An individual participant data meta-analysis of psychological interventions for preventing depression relapse
Breedvelt, J., Karyotaki, E., Warren, F. C., Brouwer, M. E., Jermann, F., Holländare, F., Klein, N. S., de Jonge, M., Klein, D. N., Farb, N. A. S., et al. (2024) · Nature Mental Health · doi:10.1038/s44220-023-00178-x · Cited by 24
“Capturing (more) baseline characteristics consistently would be important for future research.”
Self-citation
Cognitive-reminiscence therapy and usual care for depression in young adults: study protocol for a randomized controlled trial
Hallford, D. J., & Mellor, D. J. (2013) · Trials · doi:10.1186/1745-6215-14-343 · Cited by 26
“Psychological therapies for depression can provide long-term positive outcomes for sufferers of depression [8,9] and reduce the risk of further episodes [10-12].”
Background
A pilot study of cognitive remediation in remitted major depressive disorder patients
Hammar, Å., Semkovska, M., Borgen, I. M. H., Myklebost, S. B., Ronold, E. H., Sveen, T., Ueland, T., Porter, R., & Johnson, S. L. (2020) · Applied Neuropsychology Adult · doi:10.1080/23279095.2020.1726919 · Cited by 28
“Half of those diagnosed with a first episode of depression will relapse within two years (Kasper & Eder, 1994; Mueller et al., 1999; Solomon et al., 2000; Stegenga, Kamphuis, King, Nazareth, & Geerlings, 2012; Vittengl, Clark, Dunn, & Jarrett, 2007).”
Background
Stage models for major depression: Cognitive behavior therapy, mechanistic treatment targets, and the prevention of stage transition
Otto, M. W., Birk, J. L., Fitzgerald, H. E., Chauvin, G. V., Gold, A. K., & Carl, J. R. (2022) · Clinical Psychology Review · doi:10.1016/j.cpr.2022.102172 · Cited by 28
Diagnosis and Treatment of Depression in Adults With Comorbid Medical Conditions
Whooley, M. A. (2012) · JAMA · doi:10.1001/jama.2012.3466 · Cited by 26
Reducing symptoms of major depressive disorder through a systematic training of general emotion regulation skills: protocol of a randomized controlled trial
Ehret, A. M., Kowalsky, J. K., Rief, W., Hiller, W., & Berking, M. (2014) · BMC Psychiatry · doi:10.1186/1471-244x-14-20 · Cited by 25
“However, previous outcome studies also indicate that many patients still suffer from residual symptoms [6] and are likely to relapse within two years after treatment [7].”
Result
Time-course of depressive symptoms in patients with heart failure
Johansson, P., Lesman‐Leegte, I., Lundgren, J., Hillege, H. L., Hoes, A. W., Sanderman, R., van Veldhuisen, D. J., & Jaarsma, T. (2012) · Journal of Psychosomatic Research · doi:10.1016/j.jpsychores.2012.09.019 · Cited by 25
“Studies in non HF populations have shown that almost one-third of patients with remitted depression will have a recurrence of depression [26].”
Background
Cognitive-Behavioral Psychotherapy
German, R. E., & DeRubeis, R. J. (2015) · Elsevier eBooks · doi:10.1016/b978-0-12-397045-9.00018-5 · Cited by 25
Evaluation of a text-message-based maintenance intervention for Major Depressive Disorder after inpatient cognitive behavioral therapy
Schlicker, S., Ebert, D. D., Middendorf, T., Titzler, I., & Berking, M. (2017) · Journal of Affective Disorders · doi:10.1016/j.jad.2017.10.047 · Cited by 25
Factors predicting the long-term illness course in a cohort of depressed inpatients
Kuehner, C., & Huffziger, S. (2012) · European Archives of Psychiatry and Clinical Neuroscience · doi:10.1007/s00406-012-0379-7 · Cited by 25
Psychological interventions to prevent relapse in anxiety and depression: A systematic review and meta-analysis
Krijnen-de Bruin, E., Scholten, W., Muntingh, A., Maarsingh, O., van Meijel, B., van Straten, A., & Batelaan, N. (2022) · PLOS ONE · doi:10.1371/journal.pone.0272200 · Cited by 23
Using Neuroscience to Augment Behavioral Interventions for Depression
Vinograd, M., & Craske, M. G. (2020) · Harvard Review of Psychiatry · doi:10.1097/hrp.0000000000000241 · Cited by 23
“Further, a substantial number of individuals withMDDwho respond to cognitive-behavioral therapy (CBT), one of the most well-supported treatments, experience relapse or recurrence: 29% within one year and 54% within two years.(6)”
Background

Authors: Vittengl, J. R., Clark, L. A., Dunn, T. W., & Jarrett, R. B.
Affiliations: Truman State University (US)
University of Iowa (US)
The University of Texas Southwestern Medical Center (US)
ORCID: Vittengl, Jeffrey R.
Clark, Lee Anna
Jarrett, Robin B.
Venue: Journal of Consulting and Clinical Psychology
Publisher: American Psychological Association (APA)
Published: 2007
Volume: 75
Issue: 3
Pages: 475-488
ISSN: 0022-006X (ISSN-L)
1939-2117
DOI: 10.1037/0022-006x.75.3.475
PMC: PMC2630051
OpenAlex: W1981386178
Cited by: 551
References: 102
Citations by year: 2026: 11 · 2025: 15 · 2024: 24 · 2023: 19 · 2022: 22 · 2021: 30 · 2020: 34 · 2019: 42 · 2018: 35 · 2017: 32 · 2016: 36 · 2015: 36 · 2014: 38 · 2013: 29 · 2012: 37
FWCI: 4.36
Type: journal article
Language: en
Open access: green
www.ncbi.nlm.nih.gov
Locations: Journal of Consulting and Clinical Psychology (publishedVersion)
PubMed (publishedVersion)
PubMed Central (acceptedVersion)
Funders: National Institute of Mental Health (MH-58397; MH-01571)
Topics: Social Sciences › Psychology › Clinical Psychology › Psychotherapy Techniques and Applications
Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
Health Sciences › Medicine › Pharmacology (medical) › Treatment of Major Depression
Keywords: major depressive disorder, relapse prevention, recurrence prevention, cognitive behavioral therapy, acute phase treatment, psychotherapy versus pharmacotherapy, treatment discontinuation
MeSH terms: Depressive Disorder, Humans, Recurrence, Cognitive Behavioral Therapy

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Reducing relapse and recurrence in unipolar depression: a comparative meta-analysis of cognitive-behavioral therapy’s effects

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