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Impact of perceived self-efficacy in coping with stressors on components of the immune system.
Abstract
This experiment examined the impact of experimentally varied perceived self-efficacy in exercising control over stressors on components of the immunological system. Immunological changes while coping with phobic stressors were measured within an intrasubject control design that included a baseline phase, an efficacy-acquisition phase, and a maximal-efficacy phase. In each of these phases, perceived coping self-efficacy, level of autonomic and endocrine activation, and several components of the immunological system were measured. Development of strong perceived self-efficacy to control phobic stressors had an immunoenhancing effect. A slow growth of perceived self-efficacy, heart rate acceleration, and cortisol activation attenuated immunological system status during the efficacy-acquisition phase. Rapid growth of perceived self-efficacy also predicted maintenance of immunoenhancement during the maximal perceived self-efficacy phase.
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“For individuals living in environments where chronic psychosocial stress is high, exposure to stress may result in increases in serum cortisol levels, which in turn can have a negative impact on cell mediated immunity.”
From The Application of Mindfulness for Individuals Living with HIV in South Africa: a Hybrid Effectiveness-Implementation Pilot Study (2018) · cites this paper as Wiedenfeld et al., 1990
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“This relationship is supported by early prior research demonstrating a significant negative correlation between cortisol levels and CD4+ T lymphocytes (Wiedenfeld et al., 1990).”
From The Application of Mindfulness for Individuals Living with HIV in South Africa: a Hybrid Effectiveness-Implementation Pilot Study (2018) · cites this paper as Wiedenfeld et al., 1990
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Metadata
- Authors
- Wiedenfeld, S. A., O'Leary, A., Bandura, A., Brown, S., Levine, S., & Raska, K.
- Affiliations
- Stanford University (US)
- Venue
- Journal of Personality and Social Psychology
- Published
- 1990
- Volume
- 59
- Issue
- 5
- Pages
- 1082-1094
- ISSN
- 0022-3514 (ISSN-L)
- 1939-1315
- OpenAlex
- W2100613503
- Cited by
- 262
- References
- 62
- Citations by year
- 2025: 3 · 2024: 17 · 2023: 3 · 2022: 3 · 2021: 7 · 2020: 8 · 2019: 5 · 2018: 10 · 2017: 4 · 2016: 8 · 2015: 5 · 2014: 7 · 2013: 7 · 2012: 5
- FWCI
- 3.82
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of Personality and Social Psychology (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Institutes of Health (5p01hd002881-23, 5r01mh005162-25)
- National Institute of Mental Health (MH-5162-25, MH-19936)
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (HD 02881)
- Topics
- Life Sciences › Neuroscience › Behavioral Neuroscience › Stress Responses and Cortisol
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Cancer Research › Cancer, Stress, Anesthesia, and Immune Response
- Health Sciences › Health Professions › General Health Professions › Health, psychology, and well-being
- Keywords
- self-efficacy, stress coping, immune system, immune enhancement, cortisol, heart rate, autonomic activation, stress immunology
- MeSH terms
- Adaptation, Psychological, Adult, Arousal, Female, T-Lymphocytes, Helper-Inducer, Humans, Immune Tolerance, Internal-External Control, Leukocyte Count, Male, Middle Aged, Phobic Disorders, Self Concept, T-Lymphocytes, Regulatory
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