A diathesis-stress model of posttraumatic stress disorder: ecological, biological, and residual stress pathways
Abstract
The symptoms captured within the contemporary diagnostic definition of posttraumatic stress disorder (PTSD) have been studied for more than 100 years. Yet, even with increasingly advanced discoveries regarding the etiology of PTSD, a comprehensive and up-to-date etiological model that incorporates both medical and psychological research has not been described and systematically studied. The diathesis-stress model proposed here consolidates existing medical and psychological research data on etiological factors associated with PTSD into 3 causal pathways: residual stress, ecological, and biological. In combination, these pathways illuminate how PTSD might develop and who might be at higher risk for developing the disorder. Research and treatment implications related to the diathesis-stress model are discussed.
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Diathesis-stress models have been used across disciplines to integrate multiple baseline vulnerabilities or predispositions with situational stressors.
“Diathesis-stress models have been used across disciplines to integrate multiple baseline vulnerabilities or predispositions, so-called diatheses, with situational stressors (triggers) (131).”
From Where Sex Meets Gender: How Sex and Gender Come Together to Cause Sex Differences in Mental Illness (2022) · cites this paper as [131]
According to diathesis-stress models, whether or not a specific person develops a disorder depends upon the interaction between pre-existing vulnerabilities and the extent, number, timing, and severity of the stressors they experience.
“According to these models, whether or not a specific person develops a disorder depends upon the interaction between pre-existing vulnerabilities and the extent, number, timing, and severity of the stressors they experience.”
From Where Sex Meets Gender: How Sex and Gender Come Together to Cause Sex Differences in Mental Illness (2022) · cites this paper as [131]
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“McKeever and Huff (131), in their diathesis-stress model of PTSD, suggest two types of diatheses: ecological and biological, which influence each other.”
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- Authors
- McKeever, V. M., & Huff, M. E.
- Affiliations
- VA Boston Healthcare System (US)
- University of Oregon (US)
- Corresponding author
- McKeever, Victoria M.
- Venue
- Review of General Psychology
- Publisher
- SAGE Publications
- Published
- 2003-09
- Volume
- 7
- Issue
- 3
- Pages
- 237-250
- ISSN
- 1089-2680 (ISSN-L)
- 1939-1552
- OpenAlex
- W2031141141
- Cited by
- 188
- References
- 86
- Citations by year
- 2026: 4 · 2025: 12 · 2024: 7 · 2023: 20 · 2022: 16 · 2021: 9 · 2020: 13 · 2019: 10 · 2018: 7 · 2017: 13 · 2016: 6 · 2015: 13 · 2014: 11 · 2013: 11 · 2012: 7
- FWCI
- 3.72
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Review of General Psychology (publishedVersion)
- Topics
- Social Sciences › Psychology › Clinical Psychology › Posttraumatic Stress Disorder Research
- Social Sciences › Psychology › Clinical Psychology › Child Abuse and Trauma
- Social Sciences › Psychology › Clinical Psychology › Psychoanalysis and Psychopathology Research
- Keywords
- post-traumatic stress disorder, diathesis-stress model, PTSD etiology, residual stress, risk factors, causal pathways
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