The TAK1–NLK–MAPK-related pathway antagonizes signalling between β-catenin and transcription factor TCF
Ishitani, Tohru, Ninomiya-Tsuji, Jun, Nagai, Shin-ichi, Nishita, Michiru, Meneghini, Marc, Barker, Nick, Waterman, Marian, Bowerman, Bruce +3 more·1999·Nature
DOI 10.1038/21674
Cited by (616)
Items 201–300 of 616
- Early Embryonic Death in Mice Lacking the β-Catenin-Binding Protein DuplinNishiyama, Masaaki, Nakayama, Keiko, Tsunematsu, Ryosuke, Tsukiyama, Tadasuke, Kikuchi, Akira, Nakayama, Keiichi I. · 2004 · Molecular and Cellular Biology
- Morphological examination during in vitro cartilage formation by human mesenchymal stem cellsShizuko Ichinose, Motoki Tagami, Takeshi Muneta, Ichiro Sekiya · 2005 · Cell and Tissue Research
- <i>nemo-like kinase</i>
is an essential co-activator of Wnt signaling during early zebrafish developmentThorpe, Chris J., Moon, Randall T. · 2004 · Development
- Coordinate Loss of MAP3K7 and CHD1 Promotes Aggressive Prostate CancerLindsey Ulkus Rodrigues, Leah C. Rider, Cera Nieto, Lina M. Romero, Anis Karimpour‐Fard, Massimo F. Loda, Marshall Scott Lucia, Min Wu, Lihong Shi, Adela Cimic et al. · 2015 · Cancer Research
- Wnt Signaling Regulates Multipolar-to-Bipolar Transition of Migrating Neurons in the Cerebral CortexBoitard, Michael, Bocchi, Riccardo, Egervari, Kristof, Petrenko, Volodymyr, Viale, Beatrice, Gremaud, Stéphane, Zgraggen, Eloisa, Salmon, Patrick, Kiss, Jozsef Z. · 2015 · Cell Reports
- Transcriptional silencing of Dickkopf gene family by CpG island hypermethylation in human gastrointestinal cancerTadateru Maehata, Hiroaki Taniguchi, Hiroyuki Yamamoto, Katsuhiko Nosho, Yasushi Adachi, Nobuki Miyamoto, Chie Miyamoto, Noriyuki Akutsu, Satoshi Yamaoka, Fumio Itoh · 2008 · World Journal of Gastroenterology
- NLK positively regulates Wnt/β‐catenin signalling by phosphorylating LEF1 in neural progenitor cellsOta, Satoshi, Ishitani, Shizuka, Shimizu, Nobuyuki, Matsumoto, Kunihiro, Itoh, Motoyuki, Ishitani, Tohru · 2012 · The EMBO Journal
- Homeodomain-interacting protein kinases (Hipks) promote Wnt/Wg signaling through stabilization of β-catenin/Arm and stimulation of target gene expressionWendy Lee, Sharan Swarup, Joanna Chen, Tohru Ishitani, Esther M. Verheyen · 2008 · Development
- STAT3 regulates Nemo-like kinase by mediating its interaction with IL-6-stimulated TGFβ-activated kinase 1 for STAT3 Ser-727 phosphorylationKojima, Hirotada, Sasaki, Takanori, Ishitani, Tohru, Iemura, Shun-ichiro, Zhao, Hong, Kaneko, Shuhei, Kunimoto, Hiroyuki, Natsume, Tohru, Matsumoto, Kunihiro, Nakajima, Koichi · 2005 · Proceedings of the National Academy of Sciences
- TAK1–TAB1 fusion protein: a novel constitutively active mitogen-activated protein kinase kinase kinase that stimulates AP-1 and NF-κB signaling pathwaysHiroaki Sakurai, Akito Nishi, Naoya Sato, Junko Mizukami, Hidetaka Miyoshi, Takahisa Sugita · 2002 · Biochemical and Biophysical Research Communications
- Autoactivation of Transforming Growth Factor β-activated Kinase 1 Is a Sequential Bimolecular ProcessRoland Scholz, Corinne L. Sidler, Ramon F. Thali, Nicolas Winssinger, Peter Cheung, Dietbert Neumann · 2010 · Journal of Biological Chemistry
- The activation of beta-catenin by Wnt signaling mediates the effects of histone deacetylase inhibitorsMichael Bordonaro, Darina L. Lazarova, Alan C. Sartorelli · 2007 · Experimental Cell Research
- Identification of MMP-15 as an Anti-apoptotic Factor in Cancer CellsReimar Abraham, Juliane Schäfer, Mike Rothe, Johannes Bange, Pjotr G. Knyazev, Axel Ullrich · 2005 · Journal of Biological Chemistry
- Cyclin D1 over-expression correlates with beta-catenin activation, but not with H-ras mutations, and phosphorylation of Akt, GSK3beta and ERK1/2 in mouse hepatic carcinogenesisJ. Gotoh · 2003 · Carcinogenesis
- Wnt signaling drives WRM-1/β-catenin asymmetries in early C. elegans embryosKuniaki Nakamura, So Young Kim, Takao Ishidate, Yanxia Bei, Ka Ming Pang, Masaki Shirayama, Chris Trzepacz, Daniel R. Brownell, Craig C. Mello · 2005 · Genes & Development
- Modulation of Wnt signaling by Axin and AxilAkira Kikuchi · 1999 · Cytokine & Growth Factor Reviews
- Active β-Catenin Signaling Is an Inhibitory Pathway for Human Immunodeficiency Virus Replication in Peripheral Blood Mononuclear CellsAnvita Kumar, Andrew Zloza, Randall T. Moon, Jeffrey Watts, Allan R. Tenorio, Lena Al‐Harthi · 2008 · Journal of Virology
- Overexpression of EB1 in human esophageal squamous cell carcinoma (ESCC) may promote cellular growth by activating β-catenin/TCF pathwayYihua Wang, Xiaobo Zhou, Hongxia Zhu, Shuang Liu, Cuiqi Zhou, Guo Zhang, Liyan Xue, Ning Lü, Lanping Quan, Jinfeng Bai et al. · 2005 · Oncogene
- Cross-regulation of the Wnt signalling pathway: a role of MAP kinasesJürgen Behrens · 2000 · Journal of Cell Science
- Differential disruption of cell cycle pathways in small cell and non-small cell lung cancerBradley P. Coe, William Wirt Lockwood, Luc Girard, Raj Chari, Calum E. MacAulay, Stephen C. Lam, Adi F. Gazdar, John Dorrance Minna, Wan L. Lam · 2006 · British Journal of Cancer
- SALL4 is directly activated by TCF/LEF in the canonical Wnt signaling pathwayJohann Böhm, Claudio Sustmann, Christian Wilhelm, Jürgen Kohlhase · 2006 · Biochemical and Biophysical Research Communications
- Meta-analysis of genome-wide association data identifies novel susceptibility loci for obesityYu‐Fang Pei, Lei Zhang, Y. Liu, Janice Min Li, Hui Shen, Y.-Z. Liu, Q. Tian, Hao He, S. Wu, Shu Ran et al. · 2013 · Human Molecular Genetics
- NRAGE Mediates p38 Activation and Neural Progenitor Apoptosis via the Bone Morphogenetic Protein Signaling CascadeStephen E. Kendall, Chiara Battelli, Sarah Irwin, Jane Mitchell, Carlotta A. Glackin, Joseph M. Verdi · 2005 · Molecular and Cellular Biology
- TAK1 mediates microenvironment-triggered autocrine signals and promotes triple-negative breast cancer lung metastasisOihana Iriondo, Yarong Liu, Grace Lee, Mostafa Elhodaky, Christian Jimenez, Lin Li, Julie E. Lang, Pin Wang, Min Yu · 2018 · Nature Communications
- Cell-Context Dependent TCF/LEF Expression and Function: Alternative Tales of Repression, De-Repression and Activation PotentialsCatherine D. Mao, Stephen W. Byers · 2011 · Critical Reviews in Eukaryotic Gene Expression
- Impaired LRP6-TCF7L2 Activity Enhances Smooth Muscle Cell Plasticity and Causes Coronary Artery DiseaseRoshni Srivastava, Jiasheng Zhang, Gwang‐woong Go, Anand Narayanan, Timothy Nottoli, Arya Mani · 2015 · Cell Reports
- Phosphorylation by the DHIPK2 Protein Kinase Modulates the Corepressor Activity of GrouchoCheol Yong Choi, Young Ho Kim, Yong‐Ou Kim, Sang Joon Park, Eun-A Kim, William Riemenschneider, Kathleen Gajewski, Robert A. Schulz, Yongsok Kim · 2005 · Journal of Biological Chemistry
- Resveratrol modulates angiogenesis through the GSK3β/β-catenin/TCF-dependent pathway in human endothelial cellsHui Wang, Haibin Zhou, Yongxin Zou, Qiao Liu, Chenhong Guo, Guimin Gao, Changshun Shao, Yaoqin Gong · 2010 · Biochemical Pharmacology
- LATS2 Suppresses Oncogenic Wnt Signaling by Disrupting β-Catenin/BCL9 InteractionJiong Li, Xiaohong Chen, Xiangming Ding, Yingduan Cheng, Bin Zhao, Zhi-Chun Lai, Khalid Al Hezaimi, Razqallah Hakem, Kun‐Liang Guan, Cun‐Yu Wang · 2013 · Cell Reports
- PR72, a novel regulator of Wnt signaling required for Naked cuticle functionMenno P. Creyghton, Giulietta Roël, Pieter J.A. Eichhorn, E. Marielle Hijmans, Irma Maurer, Olivier Destrée, René Bernards · 2005 · Genes & Development
- FoxOs, Wnts and oxidative stress-induced bone loss: new players in the periodontitis arena?Carlo Galli, Giovanni Passeri, Guido Maria Macaluso · 2011 · Journal of Periodontal Research
- Inhibition of the Wnt Signaling Pathway by the PR61 Subunit of Protein Phosphatase 2AHideki Yamamoto, Toshihide Hinoi, Tatsuo Michiue, Akimasa Fukui, Hirofumi Usui, Veerle Janssens, Christine VAN HOOF, Jozef Goris, Makoto Asashima, Akira Kikuchi · 2001 · Journal of Biological Chemistry
- Characterization of Function of Three Domains in Dishevelled-1: DEP Domain is Responsible for Membrane Translocation of Dishevelled-1Wei Jun PAN, Shu Pang, Tao Huang, Hui Guo, Dianqing Wu, Lin Li · 2004 · Cell Research
- Nemo-like kinase, a multifaceted cell signaling regulatorIshitani, Tohru, Ishitani, Shizuka · 2013 · Cellular Signalling
- TRAF1 Is a Substrate of Caspases Activated during Tumor Necrosis Factor Receptor-α-induced ApoptosisEugen Leo, Quinn L. Deveraux, Christian Buchholtz, Kate Welsh, Shu‐ichi Matsuzawa, Henning R. Stennicke, Guy S. Salvesen, John C. Reed · 2001 · Journal of Biological Chemistry
- β-Catenin-Independent Wnt Pathways: Signals, Core Proteins, and EffectorsRichard G. James, William H. Conrad, Randall T. Moon · 2008 · Methods in molecular biology
- WNT5a is required for normal ovarian follicle development and antagonizes gonadotropin responsiveness in granulosa cells by suppressing canonical WNT signalingAtefeh Abedini, Gustavo Zamberlam, Évelyne Lapointe, Catherine Tourigny, Alexandre Boyer, Marilène Paquet, Kanako Hayashi, Hiroaki Honda, Akira Kikuchi, Christopher Alan Price et al. · 2015 · The FASEB Journal
- Nemo‐like kinase induces apoptosis and inhibits androgen receptor signaling in prostate cancer cellsKatayoon H. Emami, Lisha G. Brown, Tiffany E.M. Pitts, Xizhang Sun, Robert L. Vessella, Eva Corey · 2009 · The Prostate
- Runx1 modulates adult hair follicle stem cell emergence and maintenance from distinct embryonic skin compartmentsKaren M. Osorio, Karin C. Lilja, Tudorita Tumbar · 2011 · The Journal of Cell Biology
- Analysis of gene and protein expression during monocyte-macrophage differentiation and cholesterol loading—cDNA and protein array studyTiina T. Tuomisto, Mervi S. Riekkinen, Helena Viita, Anna–Liisa Levonen, Seppo Ylä‐Herttuala · 2005 · Atherosclerosis
- Jun NH 2 -terminal kinase (JNK) prevents nuclear β-catenin accumulation and regulates axis formation in Xenopus embryosGuanghong Liao, Qinghua Tao, Matthew J. Kofron, Juei‐Suei Chen, Aryn J. Schloemer, Roger J. Davis, Jen-Chih Hsieh, Chris Wylie, Janet Heasman, Chia-Yi Kuan · 2006 · Proceedings of the National Academy of Sciences
- Elevated SMAD1/β-catenin molecular complexes and renal medullary cystic dysplasia in ALK3 transgenic miceMeichun Hu, Tino D. Piscione, Norman D. Rosenblum · 2003 · Development
- Ph+/VE-cadherin+ identifies a stem cell–like population of acute lymphoblastic leukemia sustained by bone marrow niche cellsLin Wang, Heather A. O’Leary, James E. Fortney, Laura F. Gibson · 2007 · Blood
- DrosophilaNemo antagonizes BMP signaling by phosphorylation of Mad and inhibition of its nuclear accumulationYi Arial Zeng, Maryam Rahnama, Simon Ji Hau Wang, Worlanyo Sosu-Sedzorme, Esther M. Verheyen · 2007 · Development
- Cross‐talk between the TGFβ and Wnt signaling pathways in murine embryonic maxillary mesenchymal cellsDennis Ray Warner, Robert M. Greene, Marina Pisano · 2005 · FEBS Letters
- An Evolutionarily Conserved Motif in the TAB1 C-terminal Region Is Necessary for Interaction with and Activation of TAK1 MAPKKKKoichiro Ono, Toshihiko Ohtomo, Shigeo Sato, Yasuhiro Sugamata, Maho Suzuki, Naoki Hisamoto, Jun Ninomiya‐Tsuji, Masayuki Tsuchiya, Kunihiro Matsumoto · 2001 · Journal of Biological Chemistry
- A systems toxicology approach reveals the Wnt-MAPK crosstalk pathway mediated reproductive failure in Caenorhabditis elegans exposed to graphene oxide (GO) but not to reduced graphene oxide (rGO)Nivedita Chatterjee, Youngho Kim, Jisu Yang, Carlos P. Roca, Sang‐Woo Joo, Jinhee Choi · 2016 · Nanotoxicology
- Constitutive Activation of Wnt/β-Catenin Signaling Pathway in Migration-Active Melanoma Cells: Role of LEF-1 in Melanoma with Increased Metastatic PotentialTakashi Murakami, Sunao Toda, Mitsuo Fujimoto, Mamitaro Ohtsuki, Hugh Randolph Byers, Takafumi Etoh, Hidemi Nakagawa · 2001 · Biochemical and Biophysical Research Communications
- Patterning the C. elegans embryo: moving beyond the cell lineageMichel Labouesse, Susan E. Mango · 1999 · Trends in Genetics
- The Maternal-to-Zygotic Transition in C. elegansScott Michael Robertson, Rueyling Lin · 2015 · Current topics in developmental biology/Current Topics in Developmental Biology
- Functional Diversity of Xenopus Lymphoid Enhancer Factor/T-cell Factor Transcription Factors Relies on Combinations of Activating and Repressing ElementsDietmar Gradl, Alexander Otto König, Doris Wedlich · 2002 · Journal of Biological Chemistry
- TAK -ing aim at chemoresistance: The emerging role of MAP3K7 as a target for cancer therapyRaffaela Santoro, Carmine Carbone, Geny Piro, Paul J. Chiao, Davide Melisi · 2017 · Drug Resistance Updates
- Modulating TAK1 Expression Inhibits YAP and TAZ Oncogenic Functions in Pancreatic CancerRaffaela Santoro, Marco Zanotto, Francesca Simionato, Camilla Zecchetto, Valeria Merz, Chiara Cavallini, Geny Piro, Fabio Sabbadini, Federico Boschi, Aldo Scarpa et al. · 2019 · Molecular Cancer Therapeutics
- Identification of Two Regulatory Elements within the High Mobility Group Box Transcription Factor XTCF-4Tobias Pukrop, Dietmar Gradl, Kristine A. Henningfeld, Walter Knöchel, Doris Wedlich, Michael Kühl · 2001 · Journal of Biological Chemistry
- The role of the Drosophila TAK homologue dTAK during developmentJózsef Mihály, Lutz Kockel, Konstantin Gaengel, Ursula Weber, Dirk Bohmann, Marek Mlodzik · 2001 · Mechanisms of Development
- Involvement of NLK and Sox11 in neural induction in <i> Xenopus</i> developmentHyodo‐Miura, Junko, Urushiyama, Seiichi, Nagai, Shin‐ichi, Nishita, Michiru, Ueno, Naoto, Shibuya, Hiroshi · 2002 · Genes to Cells
- Suppression of Tak1 Promotes Prostate TumorigenesisMin Wu, Lihong Shi, Adela Cimic, Lina M. Romero, Guangchao Sui, Cynthia J. Lees, J. Mark Cline, Darren F. Seals, Joseph S. Sirintrapun, Thomas P. McCoy et al. · 2012 · Cancer Research
- Nemo is an inducible antagonist of Wingless signaling during<i>Drosophila</i>wing developmentZeng, Yi A., Verheyen, Esther M. · 2004 · Development
- Wnt Signaling in Lip and Palate DevelopmentFenglei He, Yiping Chen · 2012 · Frontiers of oral physiology/Frontiers of oral biology
- Discovering Small Molecules that Promote Cardiomyocyte Generation by Modulating Wnt SignalingTerri T. Ni, Eric J. Rellinger, Amrita Mukherjee, Shuying Xie, Lauren Stephens, Curtis A. Thorne, Kwangho Kim, Jiangyong Hu, Ethan N. Lee, Larry J. Marnett et al. · 2011 · Chemistry & Biology
- Phosphorylation of MAVS/VISA by Nemo-like kinase (NLK) for degradation regulates the antiviral innate immune responseLi, Shang-Ze, Shu, Qi-Peng, Song, Yang, Zhang, Hui-Hui, Liu, Yi, Jin, Bing-Xue, Liuyu, Tian-Zi, Li, Chao, Huang, Xi-Chen, Du, Run-Lei et al. · 2019 · Nature Communications
- NLK phosphorylates Raptor to mediate stress-induced mTORC1 inhibitionHai-Xin Yuan, Zhen Wang, Fa‐Xing Yu, Fulong Li, Ryan Charles Russell, Jenna L. Jewell, Kun‐Liang Guan · 2015 · Genes & Development
- Gene profiling during neural induction inXenopus laevis:regulation of BMP signaling by post-transcriptional mechanisms and TAB3, a novel TAK1-binding proteinIgnacio Muñoz-Sanjuán, Esther J. de H. Bell, Curtis R. Altmann, Alin Vonica, Ali H. Brivanlou · 2002 · Development
- Xenopus Zic3 controls notochord and organizer development through suppression of the Wnt/β-catenin signaling pathwayTakahiko J. Fujimi, Minoru Hatayama, Jun Aruga · 2011 · Developmental Biology
- New avenues to target Wnt/β-catenin signalingFolkert Verkaar, Guido J.R. Zaman · 2010 · Drug Discovery Today
- NEMO Kinase Contributes to Core Period Determination by Slowing the Pace of the Drosophila Circadian OscillatorWangjie Yu, Jerry H. Houl, Paul E. Hardin · 2011 · Current Biology
- Mammary gland development requires syndecan-1 to create a β-catenin/TCF-responsive mammary epithelial subpopulationBob Y. Liu, Young Chul Kim, Vicki Leatherberry, Pamela Cowin, Caroline M. Alexander · 2003 · Oncogene
- Nemo-like kinase induces apoptosis in DLD-1 human colon cancer cellsYasuda, Jun, Tsuchiya, Akira, Yamada, Tesshi, Sakamoto, Michiie, Sekiya, Takao, Hirohashi, Setsuo · 2003 · Biochemical and Biophysical Research Communications
- The Wnt Pathway in Mood DisordersGabriele Sani, Flavia Napoletano, Alberto Maria Forte, Georgios Demetrios Kotzalidis, Isabella Panaccione, Giulio Maria Porfiri, Alessio Simonetti, Matteo Caloro, Nicoletta Girardi, Carla Ludovica Telesforo et al. · 2012 · Current Neuropharmacology
- Targeted disruption of Nemo‐like kinase inhibits tumor cell growth by simultaneous suppression of cyclin D1 and CDK2 in human hepatocellular carcinomaKwang Hwa Jung, Jeong Kyu Kim, Ji Heon Noh, Jung Woo Eun, Hyun Jin Bae, Hong Jian Xie, Young Min Ahn, Won Sang Park, Jung Young Lee, Suk Woo Nam · 2010 · Journal of Cellular Biochemistry
- decapentaplegic is a direct target of dTcf repression in the Drosophila visceral mesodermXiang Sheng Yang, Moniek van Beest, Hans C. Clevers, Tamara L. Jones, Deborah A. Hursh, Mark A. Mortin · 2000 · Development
- Nemo-like kinase (NLK) acts downstream of Notch/Delta signalling to downregulate TCF during mesoderm induction in the sea urchin embryoRöttinger, Eric, Croce, Jenifer, Lhomond, Guy, Besnardeau, Lydia, Gache, Christian, Lepage, Thierry · 2006 · Development
- Bone morphogenetic proteins in tumour associated angiogenesis and implication in cancer therapiesLin Ye, Wen G. Jiang · 2015 · Cancer Letters
- Wnt-ligand-dependent interaction of TAK1 (TGF-β-activated kinase-1) with the receptor tyrosine kinase Ror2 modulates canonical Wnt-signallingAndreas Winkel, Sigmar Stricker, Przemko Tylżanowski, Virginia Seiffart, Stefan Mundlos, Gerhard Groß, Andrea Hoffmann · 2008 · Cellular Signalling
- EGF receptor/Rolled MAP kinase signalling protects cells against activated Armadillo in the Drosophila eyeMatthew Freeman, Mariann Bienz · 2001 · EMBO Reports
- A Wnt kinase network alters nuclear localization of TCF-1 in colon cancerRani Najdi, Aliba Omar Syed, Laura Arce, Heidi Theisen, J-Ht Ting, Fawzia A. Atcha, A V Nguyen, Micaela E. Martinez, Randall F. Holcombe, Robert A. Edwards et al. · 2009 · Oncogene
- Targeting the Wingless Signaling Pathway with Natural Compounds as Chemopreventive or Chemotherapeutic AgentsMarie-Hélène Teiten, François Gaascht, Mario A. Dicato, Marc F. Diederich · 2011 · Current Pharmaceutical Biotechnology
- Regulation of FOXO1 by TAK1-Nemo-like Kinase PathwaySunhong Kim, Yongsung Kim, Jiwoon Lee, Jongkyeong Chung · 2010 · Journal of Biological Chemistry
- Cell adhesion molecules and adhesion abnormalities in prostate cancerMalcolm David Mason, Gaynor Davies, Wen G. Jiang · 2002 · Critical Reviews in Oncology/Hematology
- Control over Wnt target gene expressionAndreas Hecht, Rolf Kemler · 2000
- Drosophila nemo is an essential gene involved in the regulation of programmed cell deathMirkovic, Ivana, Charish, Kristi, Gorski, Sharon M, McKnight, Kristen, Verheyen, Esther M · 2002 · Mechanisms of Development
- Nemo-like Kinase Drives Foxp3 Stability and Is Critical for Maintenance of Immune Tolerance by Regulatory T CellsFleskens, Veerle, Minutti, Carlos M., Wu, Xingmei, Wei, Ping, Pals, Cornelieke E.G.M., McCrae, James, Hemmers, Saskia, Groenewold, Vincent, Vos, Harm-Jan, Rudensky, Alexander et al. · 2019 · Cell Reports
- MicroRNA signature associated with osteogenic lineage commitmentBehnaz Bakhshandeh, Masoud Soleimani, Maryam Hafizi, Seyed Hassan Paylakhi, Nasser Ghaemi · 2012 · Molecular Biology Reports
- Emergence of TNIK inhibitors in cancer therapeuticsTesshi Yamada, Mari Masuda · 2017 · Cancer Science
- Wnt/TLR Dialog in Neuroinflammation, Relevance in Alzheimer’s DiseaseJuan Manuel Zolezzi, Nibaldo C. Inestrosa · 2017 · Frontiers in Immunology
- Identification of genes regulated by Wnt/β-catenin pathway and involved in apoptosis via microarray analysisMoli Huang, Yihua Wang, Daochun Sun, Hongxia Zhu, Yanbin Yin, Wei Zhang, Shangbin Yang, Lanping Quan, Jinfeng Bai, Shengqi Wang et al. · 2006 · BMC Cancer
- NLK functions to maintain proliferation and stemness of NSCLC and is a target of metforminDong Suwei, Liang Zeng, Zhimin Liu, Li Ruilei, Zou Yingying, Zhen Li, Chunlei Ge, Zhangchao Lai, Xue Yuanbo, Jinyan Yang et al. · 2015 · Journal of Hematology & Oncology
- Comprehending the complex connection between PKCβ, TAK1, and IKK in BCR signalingHisaaki Shinohara, Tomohiro Kurosaki · 2009 · Immunological Reviews
- Hypoxia triggers a Nur77–β-catenin feed-forward loop to promote the invasive growth of colon cancer cellsSally K. Y. To, W-J Zeng, J-Z Zeng, Alice S.T. Wong · 2014 · British Journal of Cancer
- Fezf2 promotes neuronal differentiation through localised activation of Wnt/β-catenin signalling during forebrain developmentSiwei Zhang, Jingjing Li, Robert Lea, Kris Vleminckx, Enrique Amaya · 2014 · Development
- Capillary morphogenesis gene 2 maintains gastric cancer stem-like cell phenotype by activating a Wnt/β-catenin pathwayChengdong Ji, Lang Yang, Weijing Yi, Dongfang Xiang, Yanxia Wang, Zhi-Hua Zhou, Feng Qian, Yong Ren, Wei Cui, Xia Zhang et al. · 2018 · Oncogene
- Dysregulation of Wnt/β‐catenin signaling by protein kinases in hepatocellular carcinoma and its therapeutic applicationQian Li, Mengqing Sun, Menglan Wang, Mengqing Feng, Fan Yang, Lina Li, Jianbo Zhao, Cunjie Chang, Heng Dong, Tian Xie et al. · 2021 · Cancer Science
- Opposing Activities of LIT-1/NLK and DAF-6/Patched-Related Direct Sensory Compartment Morphogenesis in C. elegansGrigorios Oikonomou, Elliot A. Perens, Yun Lu, Shigeki Watanabe, Erik M. Jørgensen, Shai Shaham · 2011 · PLoS Biology
- The effect of EBV on WIF1, NLK, and APC gene methylation and expression in gastric carcinoma and nasopharyngeal cancerZhenzhen Zhao, Wen Liu, Jincheng Liu, Jiayi Wang, Bing Luo · 2017 · Journal of Medical Virology
- Regulation of MAP Kinase by the BMP-4/TAK1 Pathway in Xenopus EctodermMousumi Goswami, Aarti R. Uzgare, Amy K. Sater · 2001 · Developmental Biology
- Nemo‐like kinase suppresses a wide range of transcription factors, including nuclear factor‐kBJun Yasuda, Hideki Yokoo, Tesshi Yamada, Issay Kitabayashi, Takao Sekiya, Hitoshi Ichikawa · 2004 · Cancer Science
- The tissue polarity gene nemo carries out multiple roles in patterning during Drosophila developmentEsther M. Verheyen, Ivana Mirkovic, Sheila J. MacLean, Caillin Langmann, Bryan C. Andrews, Christina MacKinnon · 2001 · Mechanisms of Development
- Notch signaling targets the Wingless responsiveness of a Ubx visceral mesoderm enhancer in DrosophilaNicola J. Lawrence, Tim Langdon, Keith R. Brennan, Alfonso Martínez Arias · 2001 · Current Biology
- Nemo‐like kinase is involved in NGF‐induced neurite outgrowth via phosphorylating MAP1B and paxillinIshitani, Tohru, Ishitani, Shizuka, Matsumoto, Kunihiro, Itoh, Motoyuki · 2009 · Journal of Neurochemistry
- TAK1: A Molecular Link Between Liver Inflammation, Fibrosis, Steatosis, and CarcinogenesisWeijun Wang, Wenkang Gao, Qingjing Zhu, Afnan Ahmed Mohamed Al-Asbahi, Ekihiro Seki, Ling Yang · 2021 · Frontiers in Cell and Developmental Biology