The DOI matches its Crossref record; 28 of the 29 references it cites were found in a registry or an index.
A multimodal language region in the ventral visual pathway
Abstract
Reading words and naming pictures involves the association of visual stimuli with phonological and semantic knowledge. Damage to a region of the brain in the left basal posterior temporal lobe (BA37), which is strategically situated between the visual cortex and the more anterior temporal cortex, leads to reading and naming deficits. Additional evidence implicating this region in linguistic processing comes from functional neuroimaging studies of reading in normal subjects and subjects with developmental dyslexia. Here we test whether the visual component of reading is essential for activation of BA37 by comparing cortical activations elicited by word processing in congenitally blind, late-blind and sighted subjects using functional neuroimaging. Despite the different modalities used (visual and tactile), all groups of subjects showed a common activation of BA37 by words relative to non-word letter-strings. These findings agree with the proposal that BA37 is an association area that integrates converging inputs from many regions. Our study confirms a prediction of theories of brain function that depend on convergence zones; the absence of one input (that is, visual) does not alter the response properties of such a convergence region.
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“Although nearby regions are active in word tasks that involve nonvisual modalities [17], such regions are typically significantly more anterior than the VWFA [8].”
From The visual word form area: expertise for reading in the fusiform gyrus (2003) · cites this paper as [17]
In the citing paper
“As already noted by Bu ¨chel et al. (1998), words in modalities other than the visual yielded activations more anterior (average y = 43) than those typical of the visual word form (average y = 60).”
From Specialization within the ventral stream: the case for the visual word form area (2004) · cites this paper as Büchel et al. (1998)
In the citing paper
“Second, the VWFA responds more to words or to pseudo-words than to random consonant strings that violate orthographic constraints (Beauregard et al., 1997; Bu ¨chel et al., 1998; Cohen et al., 2002; Price et al., 1996; Rees et al., 1999; Xu et al., 2001).”
From Specialization within the ventral stream: the case for the visual word form area (2004) · cites this paper as Büchel et al., 1998
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Statistical parametric maps in functional imaging: A general linear approach
Friston, K. J., Holmes, A. P., Worsley, K. J., Poline, J. ‐., Frith, C. D., & Frackowiak, R. S. J. (1994) · Human Brain Mapping · doi:10.1002/hbm.460020402 · Cited by 9,688
Self-citationThe fusiform face area: a module in human extrastriate cortex specialized for face perception
Kanwisher, N., McDermott, J., & Chun, M. M. (1997) · The Journal of Neuroscience · doi:10.1523/jneurosci.17-11-04302.1997 · Cited by 7,738
‘What’ and ‘where’ in the human brain
Ungerleider, L. G., & Haxby, J. V. (1994) · Current Opinion in Neurobiology · doi:10.1016/0959-4388(94)90066-3 · Cited by 1,913 · cited 1×
“Visual object processing, including processing of letters and word”
MethodActivation of the primary visual cortex by Braille reading in blind subjects
Sadato, N., Pascual-Leone, A., Grafman, J., Ibañez, V., Deiber, M.-P., Dold, G., & Hallett, M. (1996) · Nature · doi:10.1038/380526a0 · Cited by 1,253
Discrete Cortical Regions Associated with Knowledge of Color and Knowledge of Action
Martin, A. D., Haxby, J. V., Lalonde, F. M., Wiggs, C. L., & Ungerleider, L. G. (1995) · Science · doi:10.1126/science.270.5233.102 · Cited by 1,079
Dissociation of object and spatial visual processing pathways in human extrastriate cortex.
Haxby, J. V., Grady, C. L., Horwitz, B., Ungerleider, L. G., Mishkin, M., Carson, R. E., Herscovitch, P., Schapiro, M. B., & Rapoport, S. I. (1991) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.88.5.1621 · Cited by 1,041
Puce, A., Allison, T., Asgari, M., Gore, J. C., & McCarthy, G. (1996) · The Journal of Neuroscience · doi:10.1523/jneurosci.16-16-05205.1996 · Cited by 987
Cognitive Conjunction: A New Approach to Brain Activation Experiments
Price, C. J., & Friston, K. J. (1997) · NeuroImage · doi:10.1006/nimg.1997.0269 · Cited by 837
Self-citationActivation of Extrastriate and Frontal Cortical Areas by Visual Words and Word-Like Stimuli
Petersen, S. E., Fox, P. T., Snyder, A. Z., & Raichle, M. E. (1990) · Science · doi:10.1126/science.2396097 · Cited by 821
Word recognition in the human inferior temporal lobe
Nobre, A. C., Allison, T., & McCarthy, G. (1994) · Nature · doi:10.1038/372260a0 · Cited by 789
Large-scale neuronal theories of the brain
(1995) · Choice Reviews Online · doi:10.5860/choice.32-4182 · Cited by 628
(1993) · doi:10.1093/oso/9780195081237.001.0001 · Cited by 603
Explicit and implicit processing of words and pseudowords by adult developmental dyslexics
Brunswick, N., McCrory, E., Price, C. J., Frith, C. D., & Frith, U. (1999) · Brain · doi:10.1093/brain/122.10.1901 · Cited by 553
Self-citationDemonstrating the implicit processing of visually presented words and pseudowords
Price, C. J., Wise, R. J. S., & Frackowiak, R. S. J. (1996) · Cerebral Cortex · doi:10.1093/cercor/6.1.62 · Cited by 544
Self-citationSuzuki, W., Zola-Morgan, S. M., Squire, L., & Amaral, D. (1993) · Journal of Neuroscience · doi:10.1523/jneurosci.13-06-02430.1993 · Cited by 543
Human extrastriate visual cortex and the perception of faces words numbers and colors
Allison, T., McCarthy, G., Nobre, A., Puce, A., & Belger, A. (1994) · Cerebral Cortex · doi:10.1093/cercor/4.5.544 · Cited by 517
The anatomic basis of pure alexia
Damasio, A. R., & Damasio, H. (1983) · Neurology · doi:10.1212/wnl.33.12.1573 · Cited by 492
Farah, M. J. (1990) · Cited by 482
A functional MRI study of mental image generation
D’Esposito, M., Detre, J. A., Aguirre, G. K., Stallcup, M., Alsop, D. C., Tippet, L. J., & Farah, M. J. (1997) · Neuropsychologia · doi:10.1016/s0028-3932(96)00121-2 · Cited by 449
Different activation patterns in the visual cortex of late and congenitally blind subjects
Buchel, C. (1998) · Brain · doi:10.1093/brain/121.3.409 · Cited by 426
Self-citationRegional cerebral blood flow during object naming and word reading
Bookheimer, S. Y., Zeffiro, T. A., Blaxton, T., Gaillard, W., & Theodore, W. (1995) · Human Brain Mapping · doi:10.1002/hbm.460030206 · Cited by 410
Fiez, J. A., Raichle, M. E., Miezin, F. M., Petersen, S. E., Tallal, P. A., & Katz, W. F. (1995) · Journal of Cognitive Neuroscience · doi:10.1162/jocn.1995.7.3.357 · Cited by 311
Rumsey, J. M., Nace, K., Donohue, B., Wise, D., Maisog, J. M., & Andreason, P. (1997) · Archives of Neurology · doi:10.1001/archneur.1997.00550170042013 · Cited by 294
Basal temporal language area demonstrated by electricalstimulation
Lüders, H. O., Lesser, R. P., Hahn, J. F., Dinner, D. S., Morris, H. H., Resor, S. R., & Harrison, M. A. (1986) · Neurology · doi:10.1212/wnl.36.4.505 · Cited by 226
THE PATTERN OF NEUROPSYCHOLOGICAL IMPAIRMENT ASSOCIATED WITH LEFT POSTERIOR CEREBRAL ARTERY INFARCTS
Renzi, E. D., Zambolin, A. P., & Crisi, G. (1987) · Brain · doi:10.1093/brain/110.5.1099 · Cited by 161
Characterization of the basal temporal language area in patients with left temporal lobe epilepsy
Burnstine, T. H., Lesser, R. P., Hart, J., Uematsu, S., Zinreich, S. J., Krauss, G., Fisher, R. S., Vining, E. P. G., & Gordon, B. (1990) · Neurology · doi:10.1212/wnl.40.6.966 · Cited by 144
Anomia: Case studies with lesion localization
Foundas, A. L., Daniels, S. K., & Vasterling, J. J. (1998) · Neurocase · doi:10.1080/13554799808410605 · Cited by 89
Phonological alexia with optic and tactile anomia: A neuropsychological and anatomical study
Rapcsak, S. Z., Rothi, L. J. G., & Heilman, K. M. (1987) · Brain and Language · doi:10.1016/0093-934x(87)90063-0 · Cited by 24
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Imaging Cognition II: An Empirical Review of 275 PET and fMRI Studies
Cabeza, R., & Nyberg, L. (2000) · Journal of Cognitive Neuroscience · doi:10.1162/08989290051137585 · Cited by 3,598
Price, C. J. (2012) · NeuroImage · doi:10.1016/j.neuroimage.2012.04.062 · Cited by 2,159
Self-citationMeta-analyzing left hemisphere language areas: phonology, semantics, and sentence processing.
Vigneau, M., Beaucousin, V., Hervé, P. Y., Duffau, H., Crivello, F., Houdé, O., Mazoyer, B., & Tzourio-Mazoyer, N. (2006) · NeuroImage · doi:10.1016/j.neuroimage.2005.11.002 · Cited by 1,851
The visual word form area: expertise for reading in the fusiform gyrus
McCandliss, B. D., Cohen, L., & Dehaene, S. (2003) · Trends in Cognitive Sciences · doi:10.1016/s1364-6613(03)00134-7 · Cited by 1,489
The anatomy of language: contributions from functional neuroimaging
Price, C. J. (2000) · Journal of Anatomy · doi:10.1046/j.1469-7580.2000.19730335.x · Cited by 1,352
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Metadata
- Authors
- Büchel, C., Price, C., & Friston, K.
- Affiliations
- UCL Queen Square Institute of Neurology (GB)
- National Hospital for Neurology and Neurosurgery (GB)
- Corresponding author
- Büchel, Christian
- Venue
- Nature
- Published
- 1998-07
- Volume
- 394
- Issue
- 6690
- Pages
- 274-277
- ISSN
- 0028-0836 (ISSN-L)
- 1476-4687
- OpenAlex
- W1679149859
- Cited by
- 378
- References
- 29
- Citations by year
- 2026: 1 · 2025: 7 · 2024: 14 · 2023: 4 · 2022: 9 · 2021: 8 · 2020: 5 · 2019: 12 · 2018: 6 · 2017: 11 · 2016: 7 · 2015: 9 · 2014: 16 · 2013: 14 · 2012: 15
- FWCI
- 36.40
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- www.springer.com/tdm (tdm)
- Locations
- Nature (publishedVersion)
- PubMed (publishedVersion)
- RePEc: Research Papers in Economics (submittedVersion)
- UCL Discovery (University College London) (submittedVersion)
- Funders
- Wellcome Trust (051067)
- Topics
- Social Sciences › Psychology › Developmental and Educational Psychology › Reading and Literacy Development
- Life Sciences › Neuroscience › Cognitive Neuroscience › Neurobiology of Language and Bilingualism
- Life Sciences › Neuroscience › Cognitive Neuroscience › Tactile and Sensory Interactions
- Keywords
- ventral stream, reading, word processing, congenital blindness, late blindness, convergence region, multimodal language processing, visual word recognition
- MeSH terms
- Adult, Blindness, Humans, Language, Middle Aged, Models, Neurological, Parietal Lobe, Reading, Sensory Aids, Temporal Lobe, Tomography, Emission-Computed, Touch, Visual Pathways, Visual Perception
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