Essential role of mouse telomerase in highly proliferative organs

Cited by (999)

Items 601–700 of 999

1. Comparative methylation profiles and telomerase biology of mouse multipotent adult germline stem cells and embryonic stem cells
   Ulrich Zechner, Jessica Nolte, Marieke Wolf, Katayoon Shirneshan, Nady El Hajj, Daniela Weise, Britta Kaltwasser, Athanasios Zovoilis, Thomas Haaf, Wolfgang Engel · 2009 · Molecular Human Reproduction
2. Telomeres, Aging and Exercise: Guilty by Association?
   Warrick Chilton, Brendan J. O’Brien, Fadi Joseph Charchar · 2017 · International Journal of Molecular Sciences
3. Short dysfunctional telomeres impair the repair of arsenite‐induced oxidative damage in mouse cells
   Jennifer P.A. Newman, Birendranath Banerjee, Wanru Fang, Anuradha Poonepalli, Lakshmidevi Balakrishnan, Grace Kah Mun Low, Rabindra N. Bhattacharjee, Shizuo Akira, Manikandan Jayapal, Alirio Jose Melendez et al. · 2007 · Journal of Cellular Physiology
4. Telomerase immunity from bench to bedside: round one
   Xochtil Cortez-Gonzalez, Maurizio Zanetti · 2007 · Journal of Translational Medicine
5. HnRNP A1 phosphorylated by VRK1 stimulates telomerase and its binding to telomeric DNA sequence
   Yoon Ha Choi, Jong-Kwan Lim, Min-Woo Jeong, Kyong‐Tai Kim · 2012 · Nucleic Acids Research
6. Alterations of DNA and Chromatin Structures at Telomeres and Genetic Instability in Mouse Cells Defective in DNA Polymerase α
   Mirai Nakamura, Akira Nabetani, Takeshi Mizuno, Fumio Hanaoka, Fuyuki Ishikawa · 2005 · Molecular and Cellular Biology
7. Telomeric sequences, radiation sensitivity and genomic instability
   Simon D Bouffler, Marı́a A. Blasco, R. Cox, P. J. Smith · 2001 · International Journal of Radiation Biology
8. Persistent NF-κB activation in muscle stem cells induces proliferation-independent telomere shortening
   Elisia D. Tichy, Nuoying Ma, David Kader Sidibe, Emanuele Loro, Jacob Kocan, Delia Chen, Tejvir S. Khurana, Paul Hasty, Foteini Mourkioti · 2021 · Cell Reports
9. TopoIIα prevents telomere fragility and formation of ultra thin DNA bridges during mitosis through TRF1-dependent binding to telomeres
   Martina Stagno d ́Alcontres, Alejandro Palacios, Diego Mejias, Marı́a A. Blasco · 2014 · Cell Cycle
10. Telomeres And Telomerase in Adult Stem Cells and Pluripotent Embryonic Stem Cells
    Rosa María Marión, Marı́a A. Blasco · 2010 · Advances in experimental medicine and biology
11. Recent advances in the development of telomerase inhibitors for the treatment of cancer
    Philip J Perry, Terence C. Jenkins · 1999 · Expert Opinion on Investigational Drugs
12. Potential of Naturally Derived Compounds in Telomerase and Telomere Modulation in Skin Senescence and Aging
    Barbara Jacczak, Błażej Rubiś, Ewa Totoń · 2021 · International Journal of Molecular Sciences
13. Comparing effects of mTR and mTERT deletion on gene expression and DNA damage response: a critical examination of telomere length maintenance-independent roles of telomerase
    Sofia Luz Vidal-Cardenas, Carol W. Greider · 2009 · Nucleic Acids Research
14. Telomerase deficiency promotes oxidative stress by reducing catalase activity
    Gema Pérez‐Rivero, María Piedad Ruiz‐Torres, M. L. Díez-Marqués, Andrés Canela, José Miguel López-Novoa, Manuel Rodrı́guez-Puyol, Marı́a A. Blasco, Diego Rodrı́guez-Puyol · 2008 · Free Radical Biology and Medicine
15. Consequences of telomere shortening during lifespan
    Catarina Martins Henriques, Miguel Godinho Ferreira · 2012 · Current Opinion in Cell Biology
16. The Emerging Role of Telomerase in Cardiac Muscle Cell Growth and Survival
    Hidemasa Oh, Michael D. Schneider · 2002 · Journal of Molecular and Cellular Cardiology
17. TGF-β and cancer: Is Smad3 a repressor of hTERT gene?
    He Li, Dakang Xu, Ban‐Hock Toh, Junping Liu · 2006 · Cell Research
18. Telomeres, Telomerase, and Telomerase Inhibition: Clinical Implications for Cancer
    Ali Ahmed, Trygve O. Tollefsbol · 2003 · Journal of the American Geriatrics Society
19. Development of a Cancer-Targeted Tissue-Specific Promoter System
    Takuya Fukazawa, Yutaka Maeda, Frances M. Sladek, Laurie B. Owen‐Schaub · 2004 · Cancer Research
20. Mutant and genetically modified mice as models for studying the relationship between aging and carcinogenesis
    Vladimir Nikolaevich Anisimov · 2001 · Mechanisms of Ageing and Development
21. Telomere-dependent senescence
    David Kipling, David Wynford‐Thomas, Chris J. Jones, Arne N. Akbar, Richard Aspinall, Silvia Bacchetti, Marı́a A. Blasco, Dominique Broccoli, Ronald Anthony DePinho, Dylan R. Edwards et al. · 1999 · Nature Biotechnology
22. Epigenetic Control of Hematopoietic Stem Cell Aging The Case of Ezh2
    Gerald de Haan, ALICE GERRITS · 2007 · Annals of the New York Academy of Sciences
23. Wnt/β-Catenin Signaling Exacerbates Keloid Cell Proliferation by Regulating Telomerase
    Dongmei Yu, Yong Shang, Jian Yuan, Shuang Ding, Sai Luo, Lijun Hao · 2016 · Cellular Physiology and Biochemistry
24. Gene therapy with the TRF 1 telomere gene rescues decreased TRF 1 levels with aging and prolongs mouse health span
    Aksinya Derevyanko, Kurt Whittemore, Ralph P. Schneider, Verónica Jiménez, Fátima Bosch, Marı́a A. Blasco · 2017 · Aging Cell
25. AAV9-mediated telomerase activation does not accelerate tumorigenesis in the context of oncogenic K-Ras-induced lung cancer
    Muñoz-Lorente, Miguel A., Martínez, Paula, Tejera, Águeda, Whittemore, Kurt, Moisés-Silva, Ana Carolina, Bosch, Fàtima, Blasco, Maria A. · 2018 · PLOS Genetics
26. Role of telomeres in vascular senescence
    Tohru Minamino · 2007 · Frontiers in bioscience
27. MSH2 deficiency abolishes the anticancer and pro‐aging activity of short telomeres
    Paula Martínez, Irene Siegl‐Cachedenier, Juana María Flores, Marı́a A. Blasco · 2008 · Aging Cell
28. Telomere shortening and cell fates in mouse models of neoplasia
    Artandi, Steven E · 2002 · Trends in Molecular Medicine
29. Telomere dysfunction and stem cell ageing
    Zhenyu Ju, K. Lenhard Rudolph · 2007 · Biochimie
30. Telomerase inhibitors: targeting the vulnerable end of cancer?
    Lloyd R. Kèlland · 2000 · Anti-Cancer Drugs
31. The telomerase tale in vascular aging: regulation by estrogens and nitric oxide signaling
    Antonella Farsetti, Annalisa Grasselli, Silvia Bacchetti, Carlo Gaetano, Maurizio Colognesi Capogrossi · 2008 · Journal of Applied Physiology
32. Hematopoiesis under telomere attrition at the single-cell resolution
    Natthakan Thongon, Feiyang Ma, Andrea Santoni, Matteo Marchesini, Elena Fiorini, Ashley M. Rose, Vera Ademà, Irene Gañán‐Gómez, Emma M. Groarke, Fernanda Gutierrez‐Rodrigues et al. · 2021 · Nature Communications
33. Telomeres and telomerase in chronic myeloid leukaemia: impact for pathogenesis, disease progression and targeted therapy
    Gunhild Keller, Ute Brassat, Melanie Braig, Denise Heim, Henning Wege, Tim H. Brümmendorf · 2009 · Hematological Oncology
34. Telomerase, Telomerase Inhibition, and Cancer
    Ali Ahmed, Trygve O. Tollefsbol · 2003 · Rejuvenation Research
35. Telomerase inhibition and the future management of head-and-neck cancer
    James Anthony McCaul, Katrina Gordon, Louise Clark, Eric Kenneth Parkinson · 2002 · The Lancet Oncology
36. Up-regulation of telomerase activity in human pancreatic cancer cells after exposure to etoposide
    Norihiro Sato, Kazuhiro Mizumoto, M Kusumoto, Shoko Nishio, Naoki Maehara, Taro Urashima, Takahiro Ogawa, Masao Tanaka · 2000 · British Journal of Cancer
37. Telomerase enzyme activation and human cell immortalization
    Matthew M. Meyerson · 1998 · Toxicology Letters
38. Attenuation of telomerase activity by hammerhead ribozyme targeting human telomerase RNA induces growth retardation and apoptosis in human breast tumor cells
    Marie Yeo, Sun Young Rha, Hei‐Cheul Jeung, Shen Xiong Hu, Sanghwa Yang, Yang Seok Kim, Sung Whan An, Hyun Cheol Chung · 2004 · International Journal of Cancer
39. Lack of Detectable Transmissible Chromosomal Instability after In Vivo or In Vitro Exposure of Mouse Bone Marrow Cells to 224 Ra Alpha Particles
    Simon D Bouffler, Jackie W. Haines, Alan A. Edwards, John D. Harrison, Roger Cox · 2001 · Radiation Research
40. Possible interventions to modify aging
    Giacinto Libertini, Nicola Ferrara · 2016 · Biochemistry (Moscow)
41. Telomerase deficiency reflects age-associated changes in CD4+ T cells
    Diana M. Matthe, Oana‐Maria Thoma, Tobias Sperka, Markus Friedrich Neurath, Maximilian J. Waldner · 2022 · Immunity & Ageing
42. p53‐Dependent Mitochondrial Compensation in Heart Failure With Preserved Ejection Fraction
    Xiaonan Chen, Hao Lin, Weiyao Xiong, Jianan Pan, Shuying Huang, Shan Xu, Shufang He, Ming Lei, Alex Chia Yu Chang, Huili Zhang · 2022 · Journal of the American Heart Association
43. Telomeres as hotspots for innate immunity and inflammation
    Joe Nassour, Sara Przetocka, Jan Karlseder · 2023 · DNA repair
44. Telomeres and Telomerase in Stem Cells during Aging and Disease
    Zhenyu Ju, K. Lenhard Rudolph · 2006 · KARGER eBooks
45. Novel, chimeric, cancer‐specific, and radiation‐inducible gene promoters for suicide gene therapy of cancer
    Jie Xiong, Wen‐jie Sun, Wei‐feng Wang, Zhengkai Liao, Fuxiang Zhou, Hai‐yan Kong, Yu Xu, Conghua Xie, Yunfeng Zhou · 2011 · Cancer
46. DNA, the central molecule of aging
    Peter Lenárt, Lumír Krejčí · 2016 · Mutation research. Fundamental and molecular mechanisms of mutagenesis
47. Werner syndrome: molecular insights into the relationships between defective DNA metabolism, genomic instability, cancer and aging
    David, K. Orren · 2006 · Frontiers in bioscience
48. Promise and problems in relating cellular senescence in vitro to aging in vivo
    Harry Rubin · 2002 · Archives of Gerontology and Geriatrics
49. Telomere shortening in diaphragm and tibialis anterior muscles of aged mdx mice
    Troy C. Lund, Robert W. Grange, Dawn A. Lowe · 2007 · Muscle & Nerve
50. The Relationships of Animal Age and Caloric Intake to Cellular Replication In Vivo and In Vitro: A Review
    Norman S. Wolf, W. Pendergrass · 1999 · The Journals of Gerontology Series A
51. Advances in gene therapy of liver cirrhosis: a review.
    W. Dai, Hong-Jun Jiang · 2001 · World Journal of Gastroenterology
52. T cell senescence: a new perspective on immunotherapy in lung cancer
    Mengge Huang, Yuetong Wang, Liguang Fang, Cun Liu, Fubin Feng, Lijuan Liu, Changgang Sun · 2024 · Frontiers in Immunology
53. ATF7 mediates TNF-α–induced telomere shortening
    Toshio Maekawa, Binbin Liu, Daisuke Nakai, Keisuke Yoshida, Kenichi Nakamura, Mami Yasukawa, Manabu Koike, Kaiyo Takubo, Bruno Chatton, Fuyuki Ishikawa et al. · 2018 · Nucleic Acids Research
54. Pistachio consumption modulates DNA oxidation and genes related to telomere maintenance: a crossover randomized clinical trial
    Sı́lvia Canudas, Pablo Hernández‐Alonso, Serena Galié, Jananee Muralidharan, Lydia Morell‐Azanza, Guillermo Zalba, Jesús Francisco García-Gavilán, Amelia Martí, Jordi Salas‐Salvadó, Mònica Bulló · 2019 · American Journal of Clinical Nutrition
55. Telomere Maintenance in Laser Capture Microdissection–Purified Barrett's Adenocarcinoma Cells and Effect of Telomerase Inhibition In vivo
    Masood A. Shammas, Aamer Mahmood Qazi, Ramesh Babu Batchu, Robert C. Bertheau, Jason Y. Y. Wong, Manjula Y. Rao, Madhu Prasad, Diptiman Chanda, Selvarangan Ponnazhagan, Kenneth Carl Anderson et al. · 2008 · Clinical Cancer Research
56. The Pleiotropy of Telomerase against Cell Death
    Young Hoon Sung, Yoon Sik Choi, Cheolho Cheong, Han‐Woong Lee · 2005 · Molecules and Cells
57. Transcriptional Repression of Telomerase RNA Gene Expression by c-Jun-NH2-Kinase and Sp1/Sp3
    Alan E Bilsland, Katrina H. Stevenson, Stuart P. Atkinson, Walter Kölch, W. Nicol Keith · 2006 · Cancer Research
58. Tpp1/Acd maintains genomic stability through a complex role in telomere protection
    Tobias Else, Brian K. Theisen, Yipin Wu, Janna Hutz, Catherine E. Keegan, Gary Douglas Hammer, David O. Ferguson · 2007 · Chromosome Research
59. Limited proliferation and telomere dysfunction following telomerase inhibition in immortal murine fibroblasts.
    Jessica Boklan, Gouri J. Nanjangud, Karen L. MacKenzie, Chad May, Michel Sadelain, Malcolm A.S. Moore · 2002 · PubMed
60. Chronic In Vitro Exposure to 3′-Azido-2′, 3′-Dideoxythymidine Induces Senescence and Apoptosis and Reduces Tumorigenicity of Metastatic Mouse Mammary Tumor Cells
    Águeda M. Tejera, Daniel F. Alonso, Daniel Eduardo Gomez, Ofelia A. Olivero · 2001 · Breast Cancer Research and Treatment
61. Role of Telomerase in the Cardiovascular System
    Mark Zurek, Joachim Altschmied, Stefanie Kohlgrüber, Niloofar Ale‐Agha, Judith Haendeler · 2016 · Genes
62. Decreased expression of TERT and telomeric proteins as human ovaries age may cause telomere shortening
    Fatma Uysal, Esra Gozde Kosebent, Havva Serap Toru, Saffet Öztürk · 2020 · Journal of Assisted Reproduction and Genetics
63. Molecular Mechanisms of Alveolar Epithelial Stem Cell Senescence and Senescence-Associated Differentiation Disorders in Pulmonary Fibrosis
    Xiaojing Hong, Lihui Wang, Kexiong Zhang, Jun Liu, Junping Liu · 2022 · Cells
64. Cellular senescence and neurodegeneration
    Kristopher Holloway, Kashfia Neherin, Kha Uyen Dam, Hong Zhang · 2023 · Human Genetics
65. Telomere dysfunctional environment induces loss of quiescence and inherent impairments of hematopoietic stem cell function
    Zhangfa Song, Junling Zhang, Zhenyu Ju, K. Lenhard Rudolph · 2012 · Aging Cell
66. Telomere length analysis in goat clones and their offspring
    Dean Harvey Betts, Steven D. Perrault, Jim Petrik, Lucy Q. Lin, Laura A. Favetta, Carol L. Keefer, William Allan King · 2005 · Molecular Reproduction and Development
67. Telomeres in cancer and aging: lessons from the mouse
    Marı́a A. Blasco · 2003 · Cancer Letters
68. Strain-specific telomere length revealed by single telomere length analysis in Caenorhabditis elegans
    I. Cheung · 2004 · Nucleic Acids Research
69. Cell proliferation, carcinogenesis and diverse mechanisms of telomerase regulation
    Guido Krupp, Wolfram Klapper, Reza M. Parwaresch · 2000 · Cellular and Molecular Life Sciences
70. Cdk1 Regulates the Temporal Recruitment of Telomerase and Cdc13-Stn1-Ten1 Complex for Telomere Replication
    Chang-Ching Liu, Veena Gopalakrishnan, Lai-Fong Poon, Tingdong Yan, Shang Li · 2013 · Molecular and Cellular Biology
71. Telomeres and Cancer: From Crisis to Stability to Crisis to Stability
    Peter J. Campbell · 2012 · Cell
72. A mouse model of Werner Syndrome: what can it tell us about aging and cancer?
    Sandy S. Chang · 2004 · The International Journal of Biochemistry & Cell Biology
73. Telomere length maintenance in stem cell populations
    Nicholas D. Allen, Duncan M. Baird · 2009 · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease
74. c-Myc-mediated Regulation of Telomerase Activity Is Disabled in Immortalized Cells
    Rachid Drissi, Frédérique Zindy, Martine F. Roussel, John L. Cleveland · 2001 · Journal of Biological Chemistry
75. Growth-Related Signaling Regulates Activation of Telomerase in Regenerating Hepatocytes
    Takuo Inui, Nariyoshi Shinomiya, Masashi Fukasawa, Megumi Sugahara Kobayashi, Noritsugu Kuranaga, Shuri Ohkura, Shuhji Seki · 2002 · Experimental Cell Research
76. Knockout mice provide novel insights into meiotic chromosome and telomere dynamics
    H. Scherthan · 2003 · Cytogenetic and Genome Research
77. Telomouse—a mouse model with human-length telomeres generated by a single amino acid change in RTEL1
    Riham Smoom, Catherine Lee May, Vivian Ortiz, Mark Tigue, Hannah M. Kolev, Melissa M. Rowe, Yitzhak Reizel, Ashleigh R. Morgan, Nachshon Egyes, Dan Lichtental et al. · 2023 · Nature Communications
78. Telomere Length in Peripheral Blood Leukocytes Is Associated with Risk of Colorectal Cancer in Chinese Population
    Qin Qin, Jingwen Sun, Jieyun Yin, Li Liu, Jigui Chen, Yuxing Zhang, Tingting Li, Yun Shi, Sheng Wei, Shaofa Nie · 2014 · PLoS ONE
79. Telomerase inhibition is an effective therapeutic strategy in TERT promoter-mutant glioblastoma models with low tumor volume
    Elisa Aquilanti, Lauren Kageler, Jacqueline Watson, Duncan M. Baird, Rhiannon E. Jones, Marie Hodges, Zsofia M Szegletes, John G. Doench, Craig A. Strathdee, Jose Ricardo McFaline-Figueroa et al. · 2023 · Neuro-Oncology
80. Notch Signaling Regulates the Lifespan of Vascular Endothelial Cells via a p16-Dependent Pathway
    Yohko Yoshida, Yuka Hayashi, Masayoshi Suda, Kaoru Tateno, Sho Okada, Junji Moriya, Masataka Yokoyama, Aika Nojima, Masakatsu Yamashita, Yoshio Kobayashi et al. · 2014 · PLoS ONE
81. The Telomerase Activity of Adult Mouse Testis Resides in the Spermatogonial α6-Integrin-Positive Side Population Enriched in Germinal Stem Cells
    Lydia Riou, Henri Bastos, Bruno Lassalle, Mathieu Coureuil, J Testart, François Dominique Boussin, Isabelle Allemand, Pierre Fouchet · 2005 · Endocrinology
82. Transcriptional Silencing of a Novel hTERT Reporter Locus during In Vitro Differentiation of Mouse Embryonic Stem Cells
    Shuwen Wang, Chunguang Hu, Jiyue Zhu · 2006 · Molecular Biology of the Cell
83. Ulcerative Typhlocolitis Associated With Helicobacter mastomyrinus in Telomerase-Deficient Mice
    Kathryn A. Eaton, Judith S. Opp, Brian M. Gray, Ingrid L. Bergin, Vincent Bensan Young · 2010 · Veterinary Pathology
84. Role of Pin2/TRF1 in telomere maintenance and cell cycle control
    Xiao Zhen Zhou, Kilian Perrem, Kun Ping Lu · 2003 · Journal of Cellular Biochemistry
85. Integration of apoptosis and telomere erosion in virus-specific CD8+ T cells from blood and tonsils during primary infection
    Maria V. D. Soares · 2003 · Blood
86. Understanding telomere diseases through analysis of patient-derived iPS cells
    Luís F.Z. Batista, Steven E. Artandi · 2013 · Current Opinion in Genetics & Development
87. Microenvironmental Regulation of Telomerase Isoforms in Human Embryonic Stem Cells
    Lida Radan, Chris S. Hughes, Jonathan H. Teichroeb, F Zamora, Michael Jewer, Lynne-Marie M Postovit, Dean Harvey Betts · 2014 · Stem Cells and Development
88. Δ133p53α, a natural p53 isoform, contributes to conditional reprogramming and long-term proliferation of primary epithelial cells
    Abdul Matin Mondal, Hua Zhou, Izumi Horikawa, Frank A. Suprynowicz, Guangzhao Li, Aleksandra Dakic, Bernard Rosenthal, Lin Ye, Curtis C. Harris, Richard Schlegel et al. · 2018 · Cell Death and Disease
89. Stabilization of Dicentric Translocations through Secondary Rearrangements Mediated by Multiple Mechanisms in S. cerevisiae
    Vincent Pennaneach, Richard David Kolodner · 2009 · PLoS ONE
90. Different outcomes of telomere-dependent anaphase bridges
    Laura Tusell, Judit Pampalona, David Soler, Cristina Frías-López, Anna Genescà · 2010 · Biochemical Society Transactions
91. A Novel Transgenic Mouse Model Reveals Humanlike Regulation of an 8-kbp Human TERT Gene Promoter Fragment in Normal and Tumor Tissues
    Julia M. Ritz, Olaf Kühle, Sabine Riethdorf, Bence Sipos, Wolfgang Deppert, Christoph Englert, Çagatay Güneş · 2005 · Cancer Research
92. Telomerase, immortality and cancer
    Guido Krupp, Gabriele Bonatz, Reza M. Parwaresch · 2000 · Biotechnology annual review
93. Telomerase: not just for the elongation of telomeres
    Rodrigo T. Calado, Jichun Chen · 2006 · BioEssays
94. Cell intrinsic and extrinsic mechanisms of stem cell aging depend on telomere status
    Zhangfa Song, Zhenyu Ju, K. Lenhard Rudolph · 2008 · Experimental Gerontology
95. Ageing hard or hardly ageing?
    David Kipling, Richard Faragher · 1999 · Nature
96. Dynamics of telomere erosion in transformed and non-transformed avian cells in vitro
    Susan E. Swanberg, Mary E. Delany · 2003 · Cytogenetic and Genome Research
97. Effect of Antisense Human Telomerase RNA Transfection on the Growth of Human Gastric Cancer Cell Lines
    Kazuhito Naka, Hiroshi Yokozaki, Wataru Yasui, Hidetoshi Tahara, Eiji Tahara, Eiichi Tahara · 1999 · Biochemical and Biophysical Research Communications
98. Caudal regression in adrenocortical dysplasia (acd) mice is caused by telomere dysfunction with subsequent p53-dependent apoptosis
    Vlangos, Christopher N., O'Connor, Bridget C., Morley, Madeleine J., Krause, Andrea S., Osawa, Gail A., Keegan, Catherine E. · 2009 · Developmental Biology
99. Eroded human telomeres are more prone to remain uncapped and to trigger a G2 checkpoint response
    Jullien, Laurent, Mestre, Marie, Roux, Pierre, Gire, Véronique · 2013 · Nucleic Acids Research
100. Removing all obstacles: A critical role for p53 in promoting tissue renewal
     Schoppy, David W., Ruzankina, Yaroslava, Brown, Eric J. · 2010 · Cell Cycle