Essential role of mouse telomerase in highly proliferative organs

Lee, Han-Woong, Blasco, Maria A., Gottlieb, Geoffrey J., Horner, James W., Greider, Carol W., DePinho, Ronald A.·1998·Nature

Cited by (999)

Items 101–200 of 999

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    Davoli, Teresa, Denchi, Eros Lazzerini, de Lange, Titia · 2010 · Cell
  4. Early growth determines longevity in male rats and may be related to telomere shortening in the kidney
    Bridget J. Jennings, Susan Elizabeth Ozanne, M. W. Dorling, Charles Nicholas Hales · 1999 · FEBS Letters
  5. Manifestations and mechanisms of stem cell aging
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  6. MRT-2 checkpoint protein is required for germline immortality and telomere replication in C. elegans
    Shawn Cameron Ahmed, Jonathan Hodgkin · 2000 · Nature
  7. Side Population Cells Isolated from Porcine Dental Pulp Tissue with Self‐Renewal and Multipotency for Dentinogenesis, Chondrogenesis, Adipogenesis, and Neurogenesis
    Koichiro Iohara, Li Wu Zheng, Masataka Ito, Atsushi Tomokiyo, Kenji Matsushita, Misako Nakashima · 2006 · Stem Cells
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    Bryan, Tracy M, Cech, Thomas R · 1999 · Current Opinion in Cell Biology
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  11. DNA damage-induced type I interferon promotes senescence and inhibits stem cell function
    Yu, Qiujing, Katlinskaya, Yuliya V., Carbone, Christopher J., Zhao, Bin, Katlinski, Kanstantsin V., Zheng, Hui, Guha, Manti, Li, Ning, Chen, Qijun, Yang, Ting et al. · 2015 · Cell Reports
  12. The Saccharomyces cerevisiae WRN homolog Sgs1p participates in telomere maintenance in cells lacking telomerase
    Johnson, F. Brad, Marciniak, Robert A., McVey, Mitch, Stewart, Sheila A., Hahn, William C., Guarente, Leonard · 2001 · The EMBO Journal
  13. Diagnostic utility of telomere length testing in a hospital-based setting
    Jonathan K. Alder, Vidya Sagar Hanumanthu, Margaret A. Strong, Amy Elizabeth Dezern, Susan E. Stanley, Clifford M. Takemoto, Ludmila Danilova, Carolyn D. Applegate, Stephen G. Bolton, David W. Mohr et al. · 2018 · Proceedings of the National Academy of Sciences
  14. Virulence-related surface glycoproteins in the yeast pathogen <i>Candida glabrata</i> are encoded in subtelomeric clusters and subject to <i>RAP1</i> - and <i>SIR</i> -dependent transcriptional silencing
    De Las Peñas, Alejandro, Pan, Shih-Jung, Castaño, Irene, Alder, Jonathan, Cregg, Robert, Cormack, Brendan P. · 2003 · Genes &amp; Development
  15. Telomere Length Is a Determinant of Emphysema Susceptibility
    Alder, Jonathan K., Guo, Nini, Kembou, Frant, Parry, Erin M., Anderson, Collin J., Gorgy, Amany I., Walsh, Michael F., Sussan, Thomas, Biswal, Shyam, Mitzner, Wayne et al. · 2011 · American Journal of Respiratory and Critical Care Medicine
  16. From cells to organisms: can we learn about aging from cells in culture?
    Judith Campisi · 2001 · Experimental Gerontology
  17. Restoration of telomerase activity rescues chromosomal instability and premature aging in Terc−/− mice with short telomeres
    Samper, Enrique, Flores, Juana M, Blasco, María A · 2001 · The EMBO Reports
  18. Short Telomeres are Sufficient to Cause the Degenerative Defects Associated with Aging
    Armanios, Mary, Alder, Jonathan K., Parry, Erin M., Karim, Baktiar, Strong, Margaret A., Greider, Carol W. · 2009 · The American Journal of Human Genetics
  19. Ceramide function in the brain: when a slight tilt is enough
    Chiara Mencarelli, Pilar Martínez‐Martínez · 2012 · Cellular and Molecular Life Sciences
  20. A critical role for telomeres in suppressing and facilitating carcinogenesis
    Artandi, Steven E, DePinho, Ronald A · 2000 · Current Opinion in Genetics &amp; Development
  21. Disruption of telomerase trafficking by TCAB1 mutation causes dyskeratosis congenita
    Zhong, Franklin, Savage, Sharon A., Shkreli, Marina, Giri, Neelam, Jessop, Lea, Myers, Timothy, Chen, Renee, Alter, Blanche P., Artandi, Steven E. · 2011 · Genes &amp; Development
  22. Telomere shortening and loss of self-renewal in dyskeratosis congenita induced pluripotent stem cells
    Luís F.Z. Batista, Matthew F. Pech, Franklin L. Zhong, Ha Nam Nguyen, Kathleen T. Xie, Arthur J. Zaug, Sharon M. Crary, Jinkuk Choi, Vittorio Sebastiano, Athena M. Cherry et al. · 2011 · Nature
  23. Telomere-driven diseases and telomere-targeting therapies
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  24. Generation and in Vitro Differentiation of a Spermatogonial Cell Line
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  25. Functions of poly(ADP-ribose) polymerase in controlling telomere length and chromosomal stability
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  26. Cytotoxic T cell immunity against telomerase reverse transcriptase in humans
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  27. Studies of the molecular mechanisms in the regulation of telomerase activity
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  28. Cellular senescence in vivo: Its relevance in ageing and cardiovascular disease
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  29. Overcoming the immortality of tumour cells by telomere and telomerase based cancer therapeutics – current status and future prospects
    Lloyd R. Kèlland · 2005 · European Journal of Cancer
  30. A Platform for Rapid Exploration of Aging and Diseases in a Naturally Short-Lived Vertebrate
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  31. Genetic and epigenetic properties of mouse male germline stem cells during long-term culture
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  35. Regulation of Reactive Oxygen Species and Genomic Stability in Hematopoietic Stem Cells
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  36. No Association Between Telomere Length and Survival Among the Elderly and Oldest Old
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  39. Distinct spectra of somatic mutations accumulated with age in mouse heart and small intestine
    Martijn E.T. Dollé, Wendy K. Snyder, Jan A. Gossen, Paul H.M. Lohman, Jan Vijg · 2000 · Proceedings of the National Academy of Sciences
  40. STEM CELL FEATURES OF BENIGN AND MALIGNANT PROSTATE EPITHELIAL CELLS
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  42. Telomere Biology and Cardiovascular Disease
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  43. Molecular Pathogenesis of Pancreatic Cancer
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  44. Mitochondrial dysfunction leads to telomere attrition and genomic instability
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  45. Mice with Pulmonary Fibrosis Driven by Telomere Dysfunction
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  46. Emerging models and paradigms for stem cell ageing
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  47. Telomerase regulation and stem cell behaviour
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  48. Potent Inhibition of Telomerase by Small-Molecule Pentacyclic Acridines Capable of Interacting with G-Quadruplexes
    Sharon M. Gowan, Robert A. Heald, Malcolm F. G. Stevens, Lloyd R. Kèlland · 2001 · Molecular Pharmacology
  49. Wild-derived inbred mouse strains have short telomeres
    Michael T. Hemann · 2000 · Nucleic Acids Research
  50. Genomic Instability and Cancer
    Yixin Yao Wei Dai · 2014 · Journal of Carcinogenesis & Mutagenesis
  51. Telomeres, aging and cancer: In search of a happy ending
    Sahn-ho Kim, Patrick G. Kaminker, Judith Campisi · 2002 · Oncogene
  52. Living with Genome Instability: Plant Responses to Telomere Dysfunction
    Karel Říha, Thomas D. McKnight, Lawrence R. Griffing, Dorothy E. Shippen · 2001 · Science
  53. Telomerase Reactivation following Telomere Dysfunction Yields Murine Prostate Tumors with Bone Metastases
    Ding, Zhihu, Wu, Chang-Jiun, Jaskelioff, Mariela, Ivanova, Elena, Kost-Alimova, Maria, Protopopov, Alexei, Chu, Gerald C., Wang, Guocan, Lu, Xin, Labrot, Emma S. et al. · 2012 · Cell
  54. Short Telomeres Result in Organismal Hypersensitivity to Ionizing Radiation in Mammals
    Fermı́n A. Goytisolo, Enrique Samper, Juan Martín‐Caballero, Paul Finnon, Eloı́sa Herrera, Juana María Flores, Simon D Bouffler, Marı́a A. Blasco · 2000 · The Journal of Experimental Medicine
  55. Changes in Regenerative Capacity through Lifespan
    Yun, Maximina · 2015 · International Journal of Molecular Sciences
  56. Chromosome Break-Induced DNA Replication Leads to Nonreciprocal Translocations and Telomere Capture
    Giovanni Bosco, James E. Haber · 1998 · Genetics
  57. Role of DNA–PK in the cellular response to DNA double-strand breaks
    Sandeep Burma, David J. Chen · 2004 · DNA repair
  58. Lgr5 intestinal stem cells have high telomerase activity and randomly segregate their chromosomes
    Schepers, Arnout G, Vries, Robert, van den Born, Maaike, van de Wetering, Marc, Clevers, Hans · 2011 · The EMBO Journal
  59. Expression of mouse telomerase catalytic subunit in embryos and adult tissues
    Luis Martı́n-Rivera, Eloı́sa Herrera, Juan Pablo Albar, Marı́a A. Blasco · 1998 · Proceedings of the National Academy of Sciences
  60. Telomere length is reset during early mammalian embryogenesis
    Sonja Schaetzlein, Andrea Lucas‐Hahn, Erika Lemme, Wilfried A. Kues, Martina Maria Dorsch, Michael Peter Manns, Heiner Niemann, K. Lenhard Rudolph · 2004 · Proceedings of the National Academy of Sciences
  61. Expression of the hTERT gene is regulated at the level of transcriptional initiation and repressed by Mad1.
    Çagatay Güneş, Serge Lichtsteiner, Alain P. Vasserot, Christoph Englert · 2000 · PubMed
  62. Mammalian Ku86 mediates chromosomal fusions and apoptosis caused by critically short telomeres
    Silvia Espejel, Sonia Franco, Sandra Rodríguez, Simon D. Bouffler, Juan C. Cigudosa, María A. Blasco · 2002 · The EMBO Journal
  63. Oxidative Stress Contributes to Arsenic-induced Telomere Attrition, Chromosome Instability, and Apoptosis
    Lin Liu, James R. Trimarchi, Paula Andrea Navarro, Marı́a A. Blasco, David Lawrence Keefe · 2003 · Journal of Biological Chemistry
  64. Targeting telomeres: advances in telomere maintenance mechanism-specific cancer therapies
    Jixuan Gao, Hilda A. Pickett · 2022 · Nature reviews. Cancer
  65. TERT regulates cell survival independent of telomerase enzymatic activity
    Ying Cao, Li He, Siddhartha Deb, Junping Liu · 2002 · Oncogene
  66. Telomere Shortening Exposes Functions for the Mouse Werner and Bloom Syndrome Genes
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  68. Disruption of the telomerase catalytic subunit gene from Arabidopsis inactivates telomerase and leads to a slow loss of telomeric DNA
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  69. The role of senescence and immortalization in carcinogenesis
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  71. An evolutionary review of human telomere biology: The thrifty telomere hypothesis and notes on potential adaptive paternal effects
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  72. Genetically Engineered Mouse Models in Cancer Research
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  75. DNA damage checkpoint kinase Chk2 triggers replicative senescence
    Gire, Véronique, Roux, Pierre, Wynford‐Thomas, David, Brondello, Jean‐Marc, Dulic, Vjekoslav · 2004 · The EMBO Journal
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