Amyloid β-peptide is produced by cultured cells during normal metabolism

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3. The role of Aβ42 in Alzheimer's disease
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4. Enhanced Production and Oligomerization of the 42-residue Amyloid β-Protein by Chinese Hamster Ovary Cells Stably Expressing Mutant Presenilins
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5. Generation of Alzheimer β-amyloid protein in the trans-Golgi network in the apparent absence of vesicle formation
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6. Structural and kinetic features of amyloid β-protein fibrillogenesis
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7. The canine as an animal model of human aging and dementia
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8. Amyloid-β peptide induces oligodendrocyte death by activating the neutral sphingomyelinase–ceramide pathway
   Lee, Jiunn-Tay, Xu, Jan, Lee, Jin-Moo, Ku, Grace, Han, Xianlin, Yang, Ding-I, Chen, Shawei, Hsu, Chung Y. · 2004 · The Journal of Cell Biology
9. TNFα plus IFNγ induce the production of Alzheimer β‐amyloid peptides and decrease the secretion of APPs
   Imrich Blasko, Florentine Marx, Eberhard Steiner, Tobias Hartmann, Beatrix Grubeck-Loebenstein · 1999 · The FASEB Journal
10. Lessons from a failed γ-secretase Alzheimer trial
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11. Molecular genetics of Alzheimer’s disease
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12. β‐Amyloid neurotoxicity is mediated by a glutamate‐triggered excitotoxic cascade in rat nucleus basalis
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14. Protein phosphorylation inhibits production of Alzheimer amyloid beta/A4 peptide.
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15. Exploring the Etiology of Alzheimer Disease Using Molecular Genetics
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16. Homocysteine potentiates β‐amyloid neurotoxicity: role of oxidative stress
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17. A Furin-like Convertase Mediates Propeptide Cleavage of BACE, the Alzheimer's β-Secretase
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18. Aβ42 is More Rigid than Aβ40 at the C Terminus: Implications for Aβ Aggregation and Toxicity
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19. γ-Secretase inhibitors and modulators
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20. Highly conserved and disease‐specific patterns of carboxyterminally truncated Aβ peptides 1–37/38/39 in addition to 1–40/42 in Alzheimer's disease and in patients with chronic neuroinflammation
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21. Fibrillogenesis in Alzheimer's disease of amyloid <i>β</i> peptides and apolipoprotein E
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22. Inositol Stereoisomers Stabilize an Oligomeric Aggregate of Alzheimer Amyloid β Peptide and Inhibit Aβ-induced Toxicity
    JoAnne McLaurin, Rivka Golomb, Anna Jurewicz, Jack Perry Antel, Paul E. Fraser · 2000 · Journal of Biological Chemistry
23. Generation of amyloid β protein from its precursor is sequence specific
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24. The Role of Amyloid Precursor Protein Processing by BACE1, the β-Secretase, in Alzheimer Disease Pathophysiology*
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25. Nasal administration of amyloid-? peptide decreases cerebral amyloid burden in a mouse model of Alzheimer's disease
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26. Gender, sex steroid hormones, and Alzheimer’s disease
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27. Costimulatory Effects of Interferon-γ and Interleukin-1β or Tumor Necrosis Factor α on the Synthesis of Aβ1-40 and Aβ1-42 by Human Astrocytes
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28. Preparation and characterization of toxic Aβ aggregates for structural and functional studies in Alzheimer's disease research
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29. Calcium‐Activated Neutral Proteinase (Calpain) System in Aging and Alzheimer's Diseasea
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30. APP Processing and Synaptic Plasticity in Presenilin-1 Conditional Knockout Mice
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31. The cause of neuronal degeneration in Alzheimer’s disease
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32. Modulation of Secreted β-Amyloid Precursor Protein and Amyloid β-Peptide in Brain by Cholesterol
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33. Inhibition of γ‐secretase causes increased secretion of amyloid precursor protein C‐terminal fragments in association with exosomes
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34. Amyloid-β as a Modulator of Synaptic Plasticity
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35. Cellular Functions of the Amyloid Precursor Protein from Development to Dementia
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36. The Role of APP Processing and Trafficking Pathways in the Formation of Amyloid β‐Proteina
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37. Identification of monocyte chemoattractant protein‐1 in senile plaques and reactive microglia of Alzheimer's disease
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38. Release of amyloid beta-protein precursor derivatives by electrical depolarization of rat hippocampal slices
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39. Calcium Ionophore Increases Amyloid .beta. Peptide Production by Cultured Cells
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40. Senile plaques stimulate microglia to release a neurotoxin found in Alzheimer brain
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41. An assessment of the antioxidant and the antiamyloidogenic properties of melatonin: implications for Alzheimer's disease
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42. Non-A.beta. Component of Alzheimer's Disease Amyloid (NAC) is Amyloidogenic
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43. The role of exosomes in the processing of proteins associated with neurodegenerative diseases
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44. Reduced levels of amyloid β-peptide antibody in Alzheimer disease
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45. β-Amyloid-Induced Neuronal Apoptosis Involves c-Jun N-Terminal Kinase-Dependent Downregulation of Bcl-w
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46. Amyloid β-Protein Inhibits Ubiquitin-dependent Protein Degradation in Vitro
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47. Amyloid-β Peptide Assembly: A Critical Step in Fibrillogenesis and Membrane Disruption
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48. Human neurons derived from a teratocarcinoma cell line express solely the 695-amino acid amyloid precursor protein and produce intracellular beta-amyloid or A4 peptides.
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49. Mechanism of the cleavage specificity of Alzheimer’s disease γ-secretase identified by phenylalanine-scanning mutagenesis of the transmembrane domain of the amyloid precursor protein
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50. Serpinopathies and the conformational dementias
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51. The PI3K/Akt signaling axis in Alzheimer’s disease: a valuable target to stimulate or suppress?
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52. Characterization of Alzheimer's β-Secretase Protein BACE
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53. Reactive oxygen species and Alzheimer's disease
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54. Amyloid precursor protein (APP) and the biology of proteolytic processing: relevance to Alzheimer’s disease
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55. Constitutive secretion of tau protein by an unconventional mechanism
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56. Fresh and globular amyloid β protein (1–42) induces rapid cellular degeneration: evidence for AβP channel‐mediated cellular toxicity
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57. Chemical characterization of A beta 17-42 peptide, a component of diffuse amyloid deposits of Alzheimer disease
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58. Docosahexaenoic Acid Reduces Amyloid β Production via Multiple Pleiotropic Mechanisms
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59. apl-1, a Caenorhabditis elegans gene encoding a protein related to the human beta-amyloid protein precursor.
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60. Regulation of Amyloid Precursor Protein Cleavage
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61. The role of cell-derived oligomers of Aβ in Alzheimer's disease and avenues for therapeutic intervention
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62. Serotonin 5-HT2a and 5-HT2c Receptors Stimulate Amyloid Precursor Protein Ectodomain Secretion
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63. Lipid Rafts: Linking Alzheimer′s Amyloid‐βProduction, Aggregation, and Toxicity at Neuronal Membranes
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64. A Cell Biological Perspective on Alzheimer's Disease
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65. Review: Modulating Factors in Amyloid-β Fibril Formation
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66. The role of APP and BACE1 trafficking in APP processing and amyloid-β generation
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67. Cell cycle‐dependent regulation of the phosphorylation and metabolism of the Alzheimer amyloid precursor protein.
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69. Oxidative Stress and Neurodegenerative Disorders
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76. β-Secretase (BACE) as a drug target for alzheimer’s disease
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79. Intramembrane Proteolysis by γ-Secretase
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80. Trafficking of cell surface beta-amyloid precursor protein: retrograde and transcytotic transport in cultured neurons.
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81. The Toxicity of the Alzheimer's β-Amyloid Peptide Correlates with a Distinct Fiber Morphology
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82. High tissue content of soluble beta 1-40 is linked to cerebral amyloid angiopathy.
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83. Neutral endopeptidase can hydrolyze β-amyloid(1–40) but shows no effect on β-amyloid precursor protein metabolism
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85. NACP, the precursor protein of the non-amyloid beta/A4 protein (A beta) component of Alzheimer disease amyloid, binds A beta and stimulates A beta aggregation.
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87. Alzheimer Disease
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93. Characterization of the Interactions of Alzheimer β‐Amyloid Peptides with Phospholipid Membranes
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