Cited by 332Genetics, Aging, and Longevity in Model OrganismsHeat shock proteins researchNeurobiology and Insect Physiology Research

The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.

Chaperoning extended life

Tatar, Marc, Khazaeli, Aziz A., Curtsinger, James W.·1997·Nature

DOI 10.1038/36237

Open this paper in CoChat — free account

Integrity signals

Registry

Crossref · 10.1038/36237

Cites

1 of 1 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

We couldn’t retrieve this paper’s full text, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Heat-Induced Longevity Extension in Drosophila. I. Heat Treatment, Mortality, and Thermotolerance
Khazaeli, A. A., Tatar, M., Pletcher, S. D., & Curtsinger, J. W. (1997) · The Journals of Gerontology Series A · doi:10.1093/gerona/52a.1.b48 · Cited by 181
Self-citation

Flagged first, then by citations

Show all 1 references

Research works printed but not linked: 9

Jazwinski, S. M. Science 273, 54–59 (1996).
Lithgow, G. J. BioEssays 18, 809–815 (1996).
Murakami, S. & Johnson, T. E. Genetics 143, 1207–1218 (1996).
Heydari, A. R., Takahashi, T., Gutsmann, A., You, S. & Richardson, A. Experientia 50, 1092–1098 (1994).
Wheeler, J. C., Bieschke, E. T. & Tower, J. Proc. Natl Acad. Sci. USA 92, 10408–10412 (1995).
Lithgow, G. J., White, T. M., Melov, S. & Johnson, T. E. Proc. Natl Acad. Sci. USA 92, 7540–7544 (1995).
Welte, M. A., Tetrault, J. M., Dellavalle, R. P. & Lindquist, S. L. Curr. Biol. 13, 842–853 (1993).
Feder, M. E., Cartano, N. V., Milos, L., Krebs, R. A. & Lindquist, S. L. J. Exp. Biol. 119, 1837–1844 (1997).
Parsell, D. A. & Lindquist, S. Annu. Rev. Genet. 27, 437–496 (1993).

Sorted by citations

Oxidants, oxidative stress and the biology of ageing
Finkel, T., & Holbrook, N. J. (2000) · Nature · doi:10.1038/35041687 · Cited by 9,413
HEAT-SHOCK PROTEINS, MOLECULAR CHAPERONES, AND THE STRESS RESPONSE: Evolutionary and Ecological Physiology
Feder, M. E., & Hofmann, G. E. (1999) · Annual Review of Physiology · doi:10.1146/annurev.physiol.61.1.243 · Cited by 4,299
The physiology of life history trade-offs in animals
Zera, A. J., & Harshman, L. G. (2001) · Annual Review of Ecology and Systematics · doi:10.1146/annurev.ecolsys.32.081501.114006 · Cited by 1,577
Regulation of aging and age-related disease by DAF-16 and heat-shock factor
Hsu, A.-L., Murphy, C. T., & Kenyon, C. (2003) · Science · doi:10.1126/science.1083701 · Cited by 1,513
The evolutionary and ecological role of heat shock proteins
Sørensen, J. G., Kristensen, T. N., & Loeschcke, V. (2003) · Ecology Letters · doi:10.1046/j.1461-0248.2003.00528.x · Cited by 1,398
The Endocrine Regulation of Aging by Insulin-like Signals
Tatar, M., Bartke, A., & Antebi, A. (2003) · Science · doi:10.1126/science.1081447 · Cited by 1,327
Self-citation
Adaptation of Drosophila to temperature extremes: bringing together quantitative and molecular approaches
Hoffmann, A. A., Sørensen, J. G., & Loeschcke, V. (2003) · Journal of Thermal Biology · doi:10.1016/s0306-4565(02)00057-8 · Cited by 1,045
Biodemographic Trajectories of Longevity
Vaupel, J. W., Carey, J. R., Christensen, K., Johnson, T. E., Yashin, A. I., Holm, N. V., Iachine, I. A., Kannisto, V., Khazaeli, A. A., Liedo, P., et al. (1998) · Science · doi:10.1126/science.280.5365.855 · Cited by 803
Self-citation
Heat shock proteins in cancer: chaperones of tumorigenesis
Calderwood, S. K., Khaleque, A., Sawyer, D. B., & Ciocca, D. R. (2006) · Trends in Biochemical Sciences · doi:10.1016/j.tibs.2006.01.006 · Cited by 972
Extended Life-Span and Stress Resistance in the Drosophila Mutant methuselah
Lin, Y.-J., Seroude, L., & Benzer, S. (1998) · Science · doi:10.1126/science.282.5390.943 · Cited by 804
Genetic Analysis of Tissue Aging in Caenorhabditis elegans : A Role for Heat-Shock Factor and Bacterial Proliferation
Garigan, D., Hsu, A.-L., Fraser, A. G., Kamath, R. S., Ahringer, J., & Kenyon, C. (2002) · Genetics · doi:10.1093/genetics/161.3.1101 · Cited by 803
Stem cell aging: mechanisms, regulators and therapeutic opportunities
Oh, J., Lee, Y. D., & Wagers, A. J. (2014) · Nature Medicine · doi:10.1038/nm.3651 · Cited by 796
Regulation of Longevity in Caenorhabditis elegans by Heat Shock Factor and Molecular Chaperones
Morley, J. F., & Morimoto, R. I. (2003) · Molecular Biology of the Cell · doi:10.1091/mbc.e03-07-0532 · Cited by 741
Promoting basal levels of autophagy in the nervous system enhances longevity and oxidant resistance in adult Drosophila
Simonsen, A., Cumming, R. C., Brech, A., Isakson, P., Schubert, D. R., & Finley, K. D. (2008) · Autophagy · doi:10.4161/auto.5269 · Cited by 716
Superoxide dismutase evolution and life span regulation
Landis, G. N., & Tower, J. (2004) · Mechanisms of Ageing and Development · doi:10.1016/j.mad.2004.08.012 · Cited by 485
Protein Homeostasis and Aging: the importance of exquisite quality control
Koga, H., Kaushik, S., & Cuervo, A. M. (2011) · Ageing research reviews · doi:10.1016/j.arr.2010.02.001 · Cited by 476
FLP Recombinase-Mediated Induction of Cu/Zn-Superoxide Dismutase Transgene Expression Can Extend the Life Span of Adult Drosophila melanogaster Flies
Sun, J., & Tower, J. (1999) · Molecular and Cellular Biology · doi:10.1128/mcb.19.1.216 · Cited by 467
JNK Signaling Confers Tolerance to Oxidative Stress and Extends Lifespan in Drosophila
Wang, M. C., Bohmann, D., & Jasper, H. (2003) · Developmental Cell · doi:10.1016/s1534-5807(03)00323-x · Cited by 422
A Role for SIR-2.1 Regulation of ER Stress Response Genes in Determining C. elegans Life Span
Viswanathan, M., Kim, S. K., Berdichevsky, A., & Guarente, L. (2005) · Developmental Cell · doi:10.1016/j.devcel.2005.09.017 · Cited by 420
Slow aging during insect reproductive diapause: why butterflies, grasshoppers and flies are like worms
Tatar, M., & Yin, C. ‐. (2001) · Experimental Gerontology · doi:10.1016/s0531-5565(00)00238-2 · Cited by 340
Self-citation
EVOLUTIONARY AND MECHANISTIC THEORIES OF AGING
Hughes, K. A., & Reynolds, R. M. (2004) · Annual Review of Entomology · doi:10.1146/annurev.ento.50.071803.130409 · Cited by 345
Positive correlation between mammalian life span and cellular resistance to stress
Kapahi, P., Boulton, M. E., & Kirkwood, T. B. L. (1999) · Free Radical Biology and Medicine · doi:10.1016/s0891-5849(98)00323-2 · Cited by 326
Mechanisms that Regulate Stem Cell Aging and Life Span
Signer, R. A. J., & Morrison, S. J. (2013) · Cell Stem Cell · doi:10.1016/j.stem.2013.01.001 · Cited by 320
Lifespan extension in C. elegans by a molecular chaperone dependent upon insulin‐like signals
Walker, G. A., & Lithgow, G. J. (2003) · Aging Cell · doi:10.1046/j.1474-9728.2003.00045.x · Cited by 273
Delayed Occurrence of Fatal Neoplastic Diseases in Ames Dwarf Mice: Correlation to Extended Longevity
Ikeno, Y., Bronson, R. T., Hubbard, G. B., Lee, S., & Bartke, A. (2003) · The Journals of Gerontology Series A · doi:10.1093/gerona/58.4.b291 · Cited by 298
Life extension in Drosophila by feeding a drug
Kang, H.-L., Benzer, S., & Min, K. (2002) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.022631999 · Cited by 294
Lifespan extension of Drosophila melanogaster through hormesis by repeated mild heat stress
Hercus, M. J., Loeschcke, V., & Rattan, S. I. S. (2003) · Biogerontology · doi:10.1023/a:1024197806855 · Cited by 290
CHIP deficiency decreases longevity, with accelerated aging phenotypes accompanied by altered protein quality control
Min, J.-N., Whaley, R. A., Sharpless, N. E., Lockyer, P., Portbury, A. L., & Patterson, C. (2008) · Molecular and Cellular Biology · doi:10.1128/mcb.00296-08 · Cited by 256
Full genome gene expression analysis of the heat stress response in Drosophila melanogaster
Sørensen, J. G., Nielsen, M. M., Kruhøffer, M., Justesen, J., & Loeschcke, V. (2005) · Cell Stress and Chaperones · doi:10.1379/csc-128r1.1 · Cited by 245
Heat-shock transcription factor (HSF)-1 pathway required for Caenorhabditis elegans immunity
Singh, V., & Aballay, A. (2006) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0604050103 · Cited by 238
An accelerated assay for the identification of lifespan-extending interventions in Drosophila melanogaster
Bauer, J. H., Goupil, S., Garber, G. B., & Helfand, S. L. (2004) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0403493101 · Cited by 234
Extended longevity of Caenorhabditis elegans by knocking in extra copies of hsp70F, a homolog of mot‐2 (mortalin)/mthsp70/Grp75
Yokoyama, K., Fukumoto, K., Murakami, T., Harada, S.-I., Hosono, R., Wadhwa, R., Mitsui, Y., & Ohkuma, S. (2002) · FEBS Letters · doi:10.1016/s0014-5793(02)02470-5 · Cited by 229
HEAT SHOCK RESPONSE AND AGEING: MECHANISMS AND APPLICATIONS
Verbeke, P., Fonager, J., Clark, B. F. C., & Rattan, S. I. S. (2001) · Cell Biology International · doi:10.1006/cbir.2001.0789 · Cited by 220
Quantitative Trait Loci for Life Span in Drosophila melanogaster: Interactions With Genetic Background and Larval Density
Leips, J., & Mackay, T. F. C. (2000) · Genetics · doi:10.1093/genetics/155.4.1773 · Cited by 221
Curcumin Extends Life Span, Improves Health Span, and Modulates the Expression of Age-Associated Aging Genes in Drosophila melanogaster
Lee, K., Lee, B.-S., Semnani, S., Avanesian, A., Um, C.-Y., Jeon, H., Seong, K.-M., Yu, K., Min, K., & Jafari, M. (2010) · Rejuvenation Research · doi:10.1089/rej.2010.1031 · Cited by 217
Stress resistance as a determinate of C. elegans lifespan
Lithgow, G. J., & Walker, G. A. (2002) · Mechanisms of Ageing and Development · doi:10.1016/s0047-6374(01)00422-5 · Cited by 212
Longevity and aging: beneficial effects ofexposure to mild stress
Minois, N. (2000) · Biogerontology · doi:10.1023/a:1010085823990 · Cited by 202
Protein Repair l -Isoaspartyl Methyltransferase1 Is Involved in Both Seed Longevity and Germination Vigor in Arabidopsis
Ogé, L., Bourdais, G., Bove, J., Collet, B., Godin, B., Granier, F., Boutin, J., Job, D., Jullien, M., & Grappin, P. (2008) · The Plant Cell · doi:10.1105/tpc.108.058479 · Cited by 201
Multiple-stress analysis for isolation of Drosophila longevity genes
Wang, H., Kazemi‐Esfarjani, P., & Benzer, S. (2004) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0404648101 · Cited by 198
Bacterial Nitric Oxide Extends the Lifespan of C. elegans
Gusarov, I., Gautier, L., Смоленцева, О. А., Shamovsky, I., Eremina, S. Y., Mironov, A. S., & Nudler, E. (2013) · Cell · doi:10.1016/j.cell.2012.12.043 · Cited by 204
Larval crowding in Drosophila melanogaster induces Hsp70 expression, and leads to increased adult longevity and adult thermal stress resistance
Sørensen, J. G., & Loeschcke, V. (2001) · Journal of Insect Physiology · doi:10.1016/s0022-1910(01)00119-6 · Cited by 181
Genes That Prolong Life: Relationships of Growth Hormone and Growth to Aging and Life Span
Bartke, A., Coschigano, K. T., Kopchick, J. J., Chandrashekar, V., Mattison, J. A., Kinney, B. A., & Hauck, S. (2001) · The Journals of Gerontology Series A · doi:10.1093/gerona/56.8.b340 · Cited by 180
REPRODUCTIVE COSTS OF HEAT SHOCK PROTEIN IN TRANSGENIC DROSOPHILA MELANOGASTER
Silbermann, R. W., & Tatar, M. (2000) · Evolution · doi:10.1111/j.0014-3820.2000.tb01247.x · Cited by 180
Self-citation
Molecular chaperone function of mammalian Hsp70 and Hsp40-a review
Ohtsuka, K., & Hata, M. (2000) · International Journal of Hyperthermia · doi:10.1080/026567300285259 · Cited by 177
REPRODUCTIVE DIAPAUSE AND LIFE-HISTORY CLINES IN NORTH AMERICAN POPULATIONS OF DROSOPHILA MELANOGASTER
SCHMIDT, P. S., & Paaby, A. B. (2008) · Evolution · doi:10.1111/j.1558-5646.2008.00351.x · Cited by 171
Heat shock proteins and Drosophila aging
Tower, J. (2010) · Experimental Gerontology · doi:10.1016/j.exger.2010.09.002 · Cited by 170
Aging and molecular chaperones
Sőti, C. (2003) · Experimental Gerontology · doi:10.1016/s0531-5565(03)00185-2 · Cited by 167
Negligible Senescence during Reproductive Dormancy inDrosophila melanogaster
Tatar, M., Chien, S. A., & Priest, N. K. (2001) · The American Naturalist · doi:10.1086/321320 · Cited by 166
Self-citation
Chaperone networks: Tipping the balance in protein folding diseases
Voisine, C., Pedersen, J. S., & Morimoto, R. I. (2010) · Neurobiology of Disease · doi:10.1016/j.nbd.2010.05.007 · Cited by 166
H UMAN N EURODEGENERATIVE D ISEASE M ODELING U SING D ROSOPHILA
Bonini, N. M., & Fortini, M. (2003) · Annual Review of Neuroscience · doi:10.1146/annurev.neuro.26.041002.131425 · Cited by 169
The role of insulin and IGF-1 signaling in longevity
Katić, M., & Kahn, C. R. (2005) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-004-4297-y · Cited by 163
A COST OF REPRODUCTION IN DROSOPHILA MELANOGASTER: STRESS SUSCEPTIBILITY
Salmon, A. B., Marx, D. B., & Harshman, L. G. (2001) · Evolution · doi:10.1111/j.0014-3820.2001.tb00679.x · Cited by 156
Decreased Lifespan in the Absence of Expression of the Mitochondrial Small Heat Shock Protein Hsp22 in Drosophila
Morrow, G., Battistini, S., Zhang, P., & Tanguay, R. M. (2004) · Journal of Biological Chemistry · doi:10.1074/jbc.c400357200 · Cited by 157
Roles of molecular chaperones in the nervous system
Ohtsuka, K., & Suzuki, T. (2000) · Brain Research Bulletin · doi:10.1016/s0361-9230(00)00325-7 · Cited by 153
Genetics of Aging in the Fruit Fly,Drosophila melanogaster
Helfand, S. L., & Rogina, B. (2003) · Annual Review of Genetics · doi:10.1146/annurev.genet.37.040103.095211 · Cited by 152
DAMPs, ageing, and cancer: The ‘DAMP Hypothesis’
Huang, J., Xie, Y., Sun, X., Zeh, H. J., Kang, R., Lotze, M. T., & Tang, D. (2015) · Ageing Research Reviews · doi:10.1016/j.arr.2014.10.004 · Cited by 144
Extension of the Drosophila lifespan by overexpression of a protein repair methyltransferase
Chavous, D. A., Jackson, F. R., & O’Connor, C. M. (2001) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.251446498 · Cited by 143
Longevity and the stress response in Drosophila
Vermeulen, C. J., & Loeschcke, V. (2006) · Experimental Gerontology · doi:10.1016/j.exger.2006.09.014 · Cited by 138
Beyond the evolutionary theory of ageing, from functional genomics to evo-gero
Partridge, L., & Gems, D. (2006) · Trends in Ecology & Evolution · doi:10.1016/j.tree.2006.02.008 · Cited by 139
Heat Shock Protein Accumulation Is Upregulated in a Long-Lived Mutant of Caenorhabditis elegans
Walker, G. A., White, T. M., McColl, G., Jenkins, N. L., Babich, S. L., Candido, E. P. M., Johnson, T. E., & Lithgow, G. J. (2001) · The Journals of Gerontology Series A · doi:10.1093/gerona/56.7.b281 · Cited by 135
Heat stress-induced life span extension in yeast
Shama, S., Lai, C.-Y., Antoniazzi, J. M., Jiang, J. C., & Jazwinski, S. M. (1998) · Experimental Cell Research · doi:10.1006/excr.1998.4279 · Cited by 135
Molecular chaperones and the aging process
Sőti, C., & Csermely, P. (2000) · Biogerontology · doi:10.1023/a:1010082129022 · Cited by 131
Hormesis/preconditioning mechanisms, the nervous system and aging
Arumugam, T. V., Gleichmann, M., Tang, S., & Mattson, M. P. (2006) · Ageing Research Reviews · doi:10.1016/j.arr.2006.03.003 · Cited by 131
Sex-specific regulation of aging and apoptosis
Tower, J. (2006) · Mechanisms of Ageing and Development · doi:10.1016/j.mad.2006.05.001 · Cited by 125
Lifespan extension and elevatedhspgene expression inDrosophilacaused by histone deacetylase inhibitors
Zhao, Y., Sun, H., Lü, J., Li, X., Chen, X., Tao, D., Huang, W., & Huang, B. (2005) · Journal of Experimental Biology · doi:10.1242/jeb.01439 · Cited by 125
Heat stroke and cytokines
Leon, L. R. (2007) · Progress in brain research · doi:10.1016/s0079-6123(06)62024-4 · Cited by 127
An automated high-throughput assay for survival of the nematode Caenorhabditis elegans
Gill, M. S., Olsen, A., Sampayo, J. N., & Lithgow, G. J. (2003) · Free Radical Biology and Medicine · doi:10.1016/s0891-5849(03)00328-9 · Cited by 123
Aging-Specific Expression ofDrosophila hsp22
King, V., & Tower, J. (1999) · Developmental Biology · doi:10.1006/dbio.1998.9147 · Cited by 118
Heat shock reduces developmental competence and alters spindle configuration of bovine oocytes
Ju, J.-C., Jiang, S., Tseng, J., Parks, J. E., & Yang, X. (2005) · Theriogenology · doi:10.1016/j.theriogenology.2005.03.025 · Cited by 117
Multiple Hsp70 Isoforms in the Eukaryotic Cytosol: Mere Redundancy or Functional Specificity?
Kabani, M., & Martineau, C. N. (2008) · Current Genomics · doi:10.2174/138920208785133280 · Cited by 113
Mutation and senescence: where genetics and demography meet
Promislow, D., & Tatar, M. (1998) · Genetica · doi:10.1023/a:1017047212008 · Cited by 113
Self-citation
In Vivo toxicity assessment of gold nanoparticles in Drosophila melanogaster
Pompa, P. P., Vecchio, G., Galeone, A., Brunetti, V., Sabella, S., Maiorano, G., Falqui, A., Bertoni, G., & Cingolani, R. (2011) · Nano Research · doi:10.1007/s12274-011-0095-z · Cited by 111
Protein aggregation as a paradigm of aging
Lindner, A. B., & Démarez, A. (2009) · Biochimica et Biophysica Acta (BBA) - General Subjects · doi:10.1016/j.bbagen.2009.06.005 · Cited by 111
Protein Homeostasis, Aging and Alzheimer’s Disease
Morawe, T., Hiebel, C., Kern, A., & Behl, C. (2012) · Molecular Neurobiology · doi:10.1007/s12035-012-8246-0 · Cited by 105
Transgenic methods for increasing Drosophila life span.
Tower, J. (2000) · Mechanisms of Ageing and Development · doi:10.1016/s0047-6374(00)00152-4 · Cited by 103
Increased hsp22 RNA Levels in Drosophila Lines Genetically Selected for Increased Longevity
Kurapati, R., Passananti, H. B., Rose, M. R., & Tower, J. (2000) · The Journals of Gerontology Series A · doi:10.1093/gerona/55.11.b552 · Cited by 106
Biodiversity and ecosystem functioning in aquatic microbial systems: a new analysis of temporal variation and species richness‐predictability relations
Morin, P. J., & McGrady‐Steed, J. (2004) · Oikos · doi:10.1111/j.0030-1299.2004.13256.x · Cited by 107
Paeoniflorin, a novel heat shock protein–inducing compound
Yan, D., Saito, K., Ohmi, Y., Fujie, N., & Ohtsuka, K. (2004) · Cell Stress and Chaperones · doi:10.1379/csc-51r.1 · Cited by 105
Understanding aging: revealing order out of chaos
Dufour, É., & Larsson, N. (2004) · Biochimica et Biophysica Acta (BBA) - Bioenergetics · doi:10.1016/j.bbabio.2004.04.020 · Cited by 103
Regulation of lifespan by histone deacetylase
Chang, K. T., & Min, K. (2002) · Ageing Research Reviews · doi:10.1016/s1568-1637(02)00003-x · Cited by 99
Dissecting the genetics of longevity inDrosophila melanogaster
Paaby, A. B., & SCHMIDT, P. S. (2009) · Fly · doi:10.4161/fly.3.1.7771 · Cited by 100
Sex specific effects of heat induced hormesis in Hsf-deficient Drosophila melanogaster
Sørensen, J. G., Kristensen, T. N., KRISTENSEN, K., & Loeschcke, V. (2007) · Experimental Gerontology · doi:10.1016/j.exger.2007.09.001 · Cited by 100
Heat shock proteins and aging in Drosophila melanogaster
Morrow, G., & Tanguay, R. M. (2003) · Seminars in Cell and Developmental Biology · doi:10.1016/j.semcdb.2003.09.023 · Cited by 101
Tyrosol, a main phenol present in extra virgin olive oil, increases lifespan and stress resistance in Caenorhabditis elegans
Cañuelo, A., Gilbert‐López, B., Pacheco-Liñán, P. J., Martínez‐Lara, E., Siles, E., & Miranda‐Vizuete, A. (2012) · Mechanisms of Ageing and Development · doi:10.1016/j.mad.2012.07.004 · Cited by 95
Resveratrol Induces the Heat-Shock Response and Protects Human Cells from Severe Heat Stress
Putics, Á., Végh, É., Csermely, P., & Sőti, C. (2007) · Antioxidants and Redox Signaling · doi:10.1089/ars.2007.1866 · Cited by 95
Locomotor activity as a function of age and life span in Drosophila melanogaster overexpressing hsp70
Minois, N. (2001) · Experimental Gerontology · doi:10.1016/s0531-5565(00)00263-1 · Cited by 92
Review of molecular and biochemical responses during stress induced stimulation and hormesis in insects
Rix, R. R., & Cutler, G. C. (2022) · The Science of The Total Environment · doi:10.1016/j.scitotenv.2022.154085 · Cited by 90
Reduced levels of oxidized and glycoxidized proteins in human fibroblasts exposed to repeated mild heat shock during serial passaging in vitro
Verbeke, P. (2001) · Free Radical Biology and Medicine · doi:10.1016/s0891-5849(01)00752-3 · Cited by 90
Stress resistance and longevity in selected lines of Drosophila melanogaster☆
Harshman, L. G., Moore, K. M., Sty, M. A., & Magwire, M. M. (1999) · Neurobiology of Aging · doi:10.1016/s0197-4580(99)00091-3 · Cited by 87
Ageing and metabolism: drug discovery opportunities
Curtis, R., Geesaman, B. J., & DiStefano, P. S. (2005) · Nature Reviews Drug Discovery · doi:10.1038/nrd1777 · Cited by 86
The OLD-1 positive regulator of longevity and stress resistance is under DAF-16 regulation in Caenorhabditis elegans
Murakami, S., & Johnson, T. E. (2001) · Current Biology · doi:10.1016/s0960-9822(01)00453-5 · Cited by 82
A widespread family of heat-resistant obscure (Hero) proteins protect against protein instability and aggregation
Tsuboyama, K., Osaki, T., Suzuki, E., Kozuka‐Hata, H., Okada, Y., Oyama, M., Ikeuchi, Y., Iwasaki, S., & Tomari, Y. (2020) · PLoS Biology · doi:10.1371/journal.pbio.3000632 · Cited by 74
Context-dependent genetic architecture of Drosophila life span
Huang, W., Campbell, T., Carbone, M. A., Jones, W. E., Unselt, D., Anholt, R., & Mackay, T. (2020) · PLoS Biology · doi:10.1371/journal.pbio.3000645 · Cited by 72
Fucoxanthin increases lifespan of Drosophila melanogaster and Caenorhabditis elegans
Lashmanova, E., Proshkina, E., Zhikrivetskaya, S. O., Шевченко, О. Г., Marusich, E., Leonov, S. V., Melerzanov, A., Zhavoronkov, A. A., & Moskalev, A. (2015) · Pharmacological Research · doi:10.1016/j.phrs.2015.08.009 · Cited by 79
Modulating cellular aging in vitro: Hormetic effects of repeated mild heat stress on protein oxidation and glycation
Verbeke, P., Clark, B. F. C., & Rattan, S. I. S. (2000) · Experimental Gerontology · doi:10.1016/s0531-5565(00)00143-1 · Cited by 76
Understanding the Role of Heat Shock Protein Isoforms in Male Fertility, Aging and Apoptosis
Purandhar, K., Jena, P. K., Prajapati, B., Rajput, P., & Seshadri, S. (2014) · The World Journal of Men s Health · doi:10.5534/wjmh.2014.32.3.123 · Cited by 73
Longevity determination genes in Drosophila melanogaster
Aigaki, T., Seong, K., & Matsuo, T. (2002) · Mechanisms of Ageing and Development · doi:10.1016/s0047-6374(02)00089-1 · Cited by 71
A search for doxycycline-dependent mutations that increase Drosophila melanogaster life span identifies the VhaSFD, Sugar baby, filamin, fwd and Cctlgenes
Landis, G. N., Bhole, D., & Tower, J. (2003) · Genome biology · doi:10.1186/gb-2003-4-2-r8 · Cited by 71
Could a deficiency in growth hormone signaling be beneficial to the aging brain?
Kinney-Forshee, B. A., Kinney, N. E., Steger, R. W., & Bartke, A. (2004) · Physiology & Behavior · doi:10.1016/j.physbeh.2003.10.018 · Cited by 71
Flies and their Golden Apples: The effect of dietary restriction on Drosophila aging and age-dependent gene expression
Pletcher, S. D., Libert, S., & Skorupa, D. (2005) · Ageing Research Reviews · doi:10.1016/j.arr.2005.06.007 · Cited by 71

Authors: Tatar, M., Khazaeli, A. A., & Curtsinger, J. W.
Affiliations: University of Minnesota (US)
ORCID: Tatar, Marc
Curtsinger, James W.
Venue: Nature
Publisher: Springer Science and Business Media LLC
Published: 1997-11-06
Volume: 390
Issue: 6655
Pages: 30-30
ISSN: 0028-0836 (ISSN-L)
1476-4687
DOI: 10.1038/36237
OpenAlex: W1621906674
Cited by: 332
References: 1
Citations by year: 2026: 2 · 2025: 2 · 2024: 3 · 2023: 4 · 2022: 8 · 2021: 2 · 2020: 5 · 2019: 6 · 2018: 6 · 2017: 4 · 2016: 5 · 2015: 10 · 2014: 14 · 2013: 12 · 2012: 11
FWCI: 6.61
Type: journal article
Language: en
Open access: closed
Licence: www.springernature.com/gp/researchers/text-and-data-mining (tdm)
www.springernature.com/gp/researchers/text-and-data-mining (vor)
Locations: Nature (publishedVersion)
PubMed (publishedVersion)
RePEc: Research Papers in Economics (submittedVersion)
Topics: Life Sciences › Biochemistry, Genetics and Molecular Biology › Aging › Genetics, Aging, and Longevity in Model Organisms
Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Heat shock proteins research
Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neurobiology and Insect Physiology Research
Keywords: HSP70, heat shock proteins, lifespan extension, aging, stress response, Drosophila melanogaster, transgenic overexpression, survival
MeSH terms: Aging, Animals, Drosophila melanogaster, Longevity, Male, Temperature, HSP70 Heat-Shock Proteins, Animals, Genetically Modified

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Chaperoning extended life

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Citations

Cites

Cited by

Related

Metadata

Record

About these checks