The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Test of synergistic interactions among deleterious mutations in bacteria
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Analyzing Tables of Statistical Tests
Rice, W. R. (1989) · Evolution · doi:10.2307/2409177 · Cited by 14,571
Cited by
Dixit, A., Parnas, O., Li, B., Chen, J., Fulco, C. P., Jerby-Arnon, L., Marjanovic, N. D., Dionne, D., Burks, T., Raychowdhury, R., et al. (2016) · Cell · doi:10.1016/j.cell.2016.11.038 · Cited by 1,863
Schuldiner, M., Collins, S. R., Thompson, N. J., Denic, V., Bhamidipati, A., Punna, T., Ihmels, J., Andrews, B., Boone, C., Greenblatt, J. F., et al. (2005) · Cell · doi:10.1016/j.cell.2005.08.031 · Cited by 870
Modular epistasis in yeast metabolism
Segrè, D., DeLuna, A., Church, G. M., & Kishony, R. (2005) · Nature Genetics · doi:10.1038/ng1489 · Cited by 575
An isochromosome confers drug resistance in vivo by amplification of two genes, ERG11 and TAC1
Selmecki, A., Gerami‐Nejad, M., Paulson, C., Forche, A., & Berman, J. (2008) · Molecular Microbiology · doi:10.1111/j.1365-2958.2008.06176.x · Cited by 325
Chemical combination effects predict connectivity in biological systems
Lehár, J., Zimmermann, G. R., Krueger, A. S., Molnar, R. A., Ledell, J. T., Heilbut, A. M., Short, G. F., Giusti, L. C., Nolan, G. P., Magid, O. A., et al. (2007) · Molecular Systems Biology · doi:10.1038/msb4100116 · Cited by 275
Somatic mutations and aging: a re-evaluation
Vijg, J. (2000) · Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis · doi:10.1016/s0027-5107(99)00202-x · Cited by 243
Pathogenic mechanisms of somatic mutation and genome mosaicism in aging
Vijg, J., & Dong, X. (2020) · Cell · doi:10.1016/j.cell.2020.06.024 · Cited by 240
The contribution of epistasis to the architecture of fitness in an RNA virus
Sanjuán, R., Moya, A., & Elena, S. F. (2004) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0404125101 · Cited by 233
Self-citationThe population genetics of mutations: good, bad and indifferent
Loewe, L., & Hill, W. G. (2010) · Philosophical Transactions of the Royal Society B: Biological Sciences · doi:10.1098/rstb.2009.0317 · Cited by 226
Shadows of complexity: what biological networks reveal about epistasis and pleiotropy
Tyler, A. L., Asselbergs, F. W., Williams, S. M., & Moore, J. H. (2009) · BioEssays · doi:10.1002/bies.200800022 · Cited by 185
Lehár, J., Stockwell, B. R., Giaever, G., & Nislow, C. (2008) · Nature Chemical Biology · doi:10.1038/nchembio.120 · Cited by 172
Adaptation of Saccharomyces cerevisiae to saline stress through laboratory evolution
DHAR, R., SÄGESSER, R., WEIKERT, C., YUAN, J., & WAGNER, A. (2011) · Journal of Evolutionary Biology · doi:10.1111/j.1420-9101.2011.02249.x · Cited by 165
Holland, J. B. (2001) · Plant Breeding Reviews · doi:10.1002/9780470650196.ch2 · Cited by 147
Robustness as an evolutionary principle
Bornholdt, S., & Sneppen, K. (2000) · Proceedings of the Royal Society of London. Series B: Biological Sciences · doi:10.1098/rspb.2000.1280 · Cited by 132
Pervasive joint influence of epistasis and plasticity on mutational effects in Escherichia coli
Remold, S. K., & Lenski, R. E. (2004) · Nature Genetics · doi:10.1038/ng1324 · Cited by 116
Self-citationThe biology of digital organisms
Wilke, C. O., & Adami, C. (2002) · Trends in Ecology & Evolution · doi:10.1016/s0169-5347(02)02612-5 · Cited by 103
Manrubia, S., Cuesta, J. A., Aguirre, J., Ahnert, S. E., Altenberg, L., Cano, A. V., Catalán, P., Diaz-Uriarte, R., Elena, S. F., García-Martín, J. A., et al. (2021) · Physics of Life Reviews · doi:10.1016/j.plrev.2021.03.004 · Cited by 88
Self-citationHigh Deleterious Genomic Mutation Rate in Stationary Phase of Escherichia coli
Loewe, L., Textor, V., & Scherer, S. (2003) · Science · doi:10.1126/science.1087911 · Cited by 85
EFFECTS OF POPULATION SIZE AND MUTATION RATE ON THE EVOLUTION OF MUTATIONAL ROBUSTNESS
Elena, S. F., Wilke, C. O., Ofria, C., & Lenski, R. E. (2007) · Evolution · doi:10.1111/j.1558-5646.2007.00064.x · Cited by 73
Self-citationBarton, N. H. (2009) · Cold Spring Harbor Symposia on Quantitative Biology · doi:10.1101/sqb.2009.74.030 · Cited by 68
Age- and Temperature-Dependent Somatic Mutation Accumulation in Drosophila melanogaster
Garcia, A. M., Calder, R. B., Dollé, M. E. T., Lundell, M., Kapahi, P., & Vijg, J. (2010) · PLoS Genetics · doi:10.1371/journal.pgen.1000950 · Cited by 62
Lodato, M. A., & Walsh, C. A. (2019) · Human Molecular Genetics · doi:10.1093/hmg/ddz191 · Cited by 56
Metadata
- Authors
- Elena, S. F., & Lenski, R. E.
- Venue
- Nature
- Published
- 1997-11
- Volume
- 390
- Issue
- 6658
- Pages
- 395-398
- ISSN
- 0028-0836 (ISSN-L)
- 1476-4687
- OpenAlex
- W1565578508
- Cited by
- 404
- References
- 1
- FWCI
- 8.21
- Type
- journal article
- Language
- en
- Open access
- closed
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
