Mdm2 promotes the rapid degradation of p53

Cited by (1,057)

Items 701–800 of 1,057

  1. Regulation of MDMX nuclear import and degradation by Chk2 and 14-3-3
    LeBron, Cynthia, Chen, Lihong, Gilkes, Daniele M, Chen, Jiandong · 2006 · The EMBO Journal
  2. Proteolysis of MOB1 by the ubiquitin ligase praja2 attenuates Hippo signalling and supports glioblastoma growth
    Luca Lignitto, Antonietta Arcella, Maria Sepe, Laura Rinaldi, Rossella Delle Donne, Adriana Gallo, Eduard Stefan, Verena A. Bachmann, Maria Antonietta Oliva, Clelia Tiziana Storlazzi et al. · 2013 · Nature Communications
  3. MEG3: a novel long noncoding potentially tumour-suppressing RNA in meningiomas
    Vladimír Balik, Josef Srovnal, Igor J. Sulla, Ondřej Kalita, Tatiana Foltánová, Miroslav Vaverka, Lumír Hrabálek, Marián Hajdúch · 2013 · Journal of Neuro-Oncology
  4. Fluorescent probes for proteolysis: Tools for drug discovery
    Jacques Neefjes, Nico P. Dantuma · 2004 · Nature Reviews Drug Discovery
  5. Osmotic Shock Induces G1 Arrest through p53 Phosphorylation at Ser33 by Activated p38MAPK without Phosphorylation at Ser15 and Ser20
    Hiroto Kishi, Kazumi Nakagawa, Mitsuhiro Matsumoto, Moritaka Suga, Masayuki Ando, Yoichi Taya, Masaru Yamaizumi · 2001 · Journal of Biological Chemistry
  6. Cytokine control of developmental programs in normal hematopoiesis and leukemia
    Joseph Lotem, Leo Sachs · 2002 · Oncogene
  7. Activation of the Cell Death Program by Nitric Oxide Involves Inhibition of the Proteasome
    Sandra Glockzin, Andreas von Knethen, Martin Scheffner, Bernhard Brüne · 1999 · Journal of Biological Chemistry
  8. Tetramer formation of tumor suppressor protein p53: Structure, function, and applications
    Rui Kamada, 侑 戸口, Takao Nomura, Toshiaki Imagawa, Kazuyasu Sakaguchi · 2015 · Biopolymers
  9. Biological determinants of radioresistance and their remediation in pancreatic cancer
    Parthasarathy Seshacharyulu, Michael J. Baine, Joshua J. Souchek, Melanie Menning, Sukhwinder Kaur, Ying Yan, Michel M. Ouellette, Maneesh Jain, Chi H. Lin, Surinder K. Batra · 2017 · Biochimica et Biophysica Acta (BBA) - Reviews on Cancer
  10. Changes in body mass index and prevalence of overweight in survivors of childhood acute lymphoblastic leukemia: Role of cranial irradiation
    Charles A. Sklar, Ann C. Mertens, Andrew W. Walter, Deanna S. Mitchell, Mark E. Nesbit, Maura O’Leary, Raymond J. Hutchinson, Anna T. Meadows, Leslie L. Robison · 2000 · Medical and Pediatric Oncology
  11. p53 tetramerization: at the center of the dominant-negative effect of mutant p53
    Jovanka Gencel‐Augusto, Guillermina Lozano · 2020 · Genes & Development
  12. Molecular targets of apigenin in colorectal cancer cells: Involvement of p21, NAG-1 and p53
    Yi Zhong, Chutwadee Krisanapun, Seong‐Ho Lee, Thararat Nualsanit, Carl E. Sams, Penchom Peungvicha, Seung Joon Baek · 2010 · European Journal of Cancer
  13. Apoptosis Associated with Deregulated E2F Activity Is Dependent on E2F1 and Atm/Nbs1/Chk2
    Harry A. Rogoff, Mary Pickering, Fiona M. Frame, Michelle E. Debatis, Yolanda Sánchez, Stephen N. Jones, Timothy F. Kowalik · 2004 · Molecular and Cellular Biology
  14. Groups of p53 target genes involved in specific p53 downstream effects cluster into different classes of DNA binding sites
    Qian Hua, Ting Wang, Louie Naumovski, Charles D. Lopez, Rainer Karl Brachmann · 2002 · Oncogene
  15. Down-regulation of the stathmin/Op18 and FKBP25 genes following p53 induction
    Jaimo Ahn, Maureen E. Murphy, Stephen A. Kratowicz, Alan Wang, Arnold J. Levine, Donna L. George · 1999 · Oncogene
  16. Keeping an old friend under control: regulation of p53 stability
    Michael H.G. Kubbutat, Karen H. Vousden · 1998 · Molecular Medicine Today
  17. Cadmium Renal Toxicity via Apoptotic Pathways
    Yasuyuki Fujiwara, Jin‐Yong Lee, Maki Tokumoto, Masahiko Satoh · 2012 · Biological and Pharmaceutical Bulletin
  18. DNA replication stress and cancer chemotherapy
    Hiroyuki Kitao, Makoto Iimori, Yuki Kataoka, Takeshi Wakasa, Eriko Tokunaga, Hiroshi Saeki, Eiji Oki, Yoshihiko Maehara · 2017 · Cancer Science
  19. A Chromatin-associated and Transcriptionally Inactive p53-Mdm2 Complex Occurs in mdm2 SNP309 Homozygous Cells
    Nicoleta C. Arva, Tamara Gopen, Kathryn E. Talbott, Latoya E. Campbell, Agustin Chicas, David E. White, Gareth L. Bond, Arnold J. Levine, Jill Bargonetti · 2005 · Journal of Biological Chemistry
  20. PTEN and phosphatidylinositol 3'-kinase inhibitors up-regulate p53 and block tumor-induced angiogenesis: evidence for an effect on the tumor and endothelial compartment.
    Jing Dong Su, Lindsey D. Mayo, David B. Donner, Donald L. Durden · 2003 · PubMed
  21. Roles of the functional loss of p53 and other genes in astrocytoma tumorigenesis and progression
    Michimasa Nozaki, Mitsuhiro Tada, Hiroyuki Kobayashi, C L Zhang, Yutaka Sawamura, Hiroshi Abe, Nobuaki Ishii, Erwin G. Van Meir · 1999 · Neuro-Oncology
  22. Activation of p53 transcriptional activity requires ATM's kinase domain and multiple N-terminal serine residues of p53
    Turenne, Gaetan A, Paul, Proma, Laflair, Lareina, Price, Brendan D · 2001 · Oncogene
  23. Increased Sensitivity to UV Radiation in Mice with a p53 Point Mutation at Ser389
    Bruins, Wendy, Zwart, Edwin, Attardi, Laura D., Iwakuma, Tomoo, Hoogervorst, Esther M., Beems, Rudolf B., Miranda, Barbara, van Oostrom, Conny T. M., van den Berg, Jolanda, van den Aardweg, Gerard J. et al. · 2004 · Molecular and Cellular Biology
  24. The ribosomal protein S26 regulates p53 activity in response to DNA damage
    Dan Cui, L Li, Huiqiang Lou, Hong‐Wei Sun, S.H.O. Ngai, Genze Shao, Jun Tang · 2013 · Oncogene
  25. Regulation of the MDM2-p53 Pathway by Ribosomal Protein L11 Involves a Post-ubiquitination Mechanism
    Mu‐Shui Dai, Dingding Shi, Yetao Jin, Xiao‐Xin Sun, Yanping Zhang, Steven R. Grossman, Hua Lu · 2006 · Journal of Biological Chemistry
  26. Critical Contribution of the MDM2 Acidic Domain to p53 Ubiquitination
    Hidehiko Kawai, Dmitri Wiederschain, Zhi-Min Yuan · 2003 · Molecular and Cellular Biology
  27. Regulation of hepatocyte fate by interferon-γ
    Christopher J. Horras, Cheri L. Lamb, Kristen A. Mitchell · 2011 · Cytokine & Growth Factor Reviews
  28. Mdm2-mediated NEDD8 Modification of TAp73 Regulates Its Transactivation Function
    Ian R. Watson, Alvaro Blanch, Dan C.C. Lin, Michael Ohh, Meredith S. Irwin · 2006 · Journal of Biological Chemistry
  29. SUMO-Specific Protease 2 Is Essential for Modulating p53-Mdm2 in Development of Trophoblast Stem Cell Niches and Lineages
    Shang-Yi Chiu, Naoya Asai, Frank D. Costantini, Wei Hsu · 2008 · PLoS Biology
  30. Regulation of cellular senescence via the FOXO 4‐p53 axis
    Benjamin M. R. Bourgeois, Tobias Madl · 2018 · FEBS Letters
  31. The Roles of the Ubiquitin–Proteasome System in the Endoplasmic Reticulum Stress Pathway
    Junyan Qu, Tingting Zou, Zhenghong Lin · 2021 · International Journal of Molecular Sciences
  32. Protein quality control and degradation in cardiomyocytes
    Xuejun Wang, Huabo Su, Mark John Ranek · 2008 · Journal of Molecular and Cellular Cardiology
  33. Increased apoptosis induction by 121F mutant p53
    Elisabeth Saller, Ed Tom, Michèle Brunori, Michèle Otter, Anne Estreicher, David H. Mack, Richard D Iggo · 1999 · The EMBO Journal
  34. Notch1 Is Required for Kras-Induced Lung Adenocarcinoma and Controls Tumor Cell Survival via p53
    Silvia Licciulli, Jacqueline L. Avila, Linda Hanlon, Scott A. Troutman, Matteo Cesaroni, Smitha Kota, Brian Keith, Marie Celeste Simon, Ellen Puré, Freddy Radtke et al. · 2013 · Cancer Research
  35. Multiple Stress Signals Activate Mutant p53 In Vivo
    Young‐Ah Suh, Sean M. Post, Ana C. Elizondo-Fraire, Daniela R. Macció, James G. Jackson, Adel K. El‐Naggar, Carolyn Van Pelt, Tamara Terzian, Guillermina Lozano · 2011 · Cancer Research
  36. Ribosome biogenesis and cancer
    Massimo Derenzini, Lorenzo Montanaro, Davide Treré · 2017 · Acta Histochemica
  37. The Involvement of Ubiquitination Machinery in Cell Cycle Regulation and Cancer Progression
    Tingting Zou, Zhenghong Lin · 2021 · International Journal of Molecular Sciences
  38. dapk1, encoding an activator of a p19ARF-p53-mediated apoptotic checkpoint, is a transcription target of p53
    Alain Martoriati, Gilles Doumont, Myriam Alcalay, Eric Bellefroid, Pier Giuseppe Pelicci, Jean‐Christophe Marine · 2004 · Oncogene
  39. Degradation of Myogenic Transcription Factor MyoD by the Ubiquitin Pathway In Vivo and In Vitro: Regulation by Specific DNA Binding
    Ossama A. Hatoum, Shlomit Gross-Mesilaty, Kristin Breitschopf, Aviad Hoffman, Hedva Gonen, Aaron J. Ciechanover, Eyal Bengal · 1998 · Molecular and Cellular Biology
  40. USP7 Is a Master Regulator of Genome Stability
    Valles, Gabrielle J., Bezsonova, Irina, Woodgate, Roger, Ashton, Nicholas W. · 2020 · Frontiers in Cell and Developmental Biology
  41. Novel targeted therapeutics: inhibitors of MDM2, ALK and PARP
    Yuan Yuan, Yu-Min Liao, Chung-Tsen Hsueh, Hamid Mirshahidi · 2011 · Journal of Hematology & Oncology
  42. PSMD2 regulates breast cancer cell proliferation and cell cycle progression by modulating p21 and p27 proteasomal degradation
    Yunhai Li, Jing Huang, Beilei Zeng, Dejuan Yang, Jiazheng Sun, Xuedong Yin, Mengqi Lu, Zhu Qiu, Weiyan Peng, Tingxiu Xiang et al. · 2018 · Cancer Letters
  43. The functions and regulation of Smurfs in cancers
    Lin Fu, Chun‐Ping Cui, Xueli Zhang, Lingqiang Zhang · 2019 · Seminars in Cancer Biology
  44. Ubiquitin becomes ubiquitous in cancer
    Dingding Shi, Steven R. Grossman · 2010 · Cancer Biology & Therapy
  45. The Arf tumor suppressor gene promotes hyaloid vascular regression during mouse eye development
    Robyn N. McKeller, Jennifer L. Fowler, Justine J. Cunningham, Nikita Warner, Richard Jay Smeyne, Frédérique Zindy, Stephen X. Skapek · 2002 · Proceedings of the National Academy of Sciences
  46. SIAH-1 promotes apoptosis and tumor suppression through a network involving the regulation of protein folding, unfolding, and trafficking: Identification of common effectors with p53 and p21 Waf1
    Jean-Pierre Roperch, Florence Lethrone, Sylvie Prieur, Laurence Piouffre, David Israeli, Marcel Tuynder, Mona Nemani, Patricia Pasturaud, Marie‐Claude Gendron, Jean B. Dausset et al. · 1999 · Proceedings of the National Academy of Sciences
  47. Ablation of Key Oncogenic Pathways by RITA-Reactivated p53 Is Required for Efficient Apoptosis
    Vera V. Grinkevich, Fedor Nikulenkov, Yao Shi, Martin Enge, Wenjie Bao, Alena Malyukova, Angela Gluch, Alexander E Kel, Olle Sangfelt, Galina Selivanova · 2009 · Cancer Cell
  48. The Ubiquitin-conjugating Enzymes UbcH7 and UbcH8 Interact with RING Finger/IBR Motif-containing Domains of HHARI and H7-AP1
    T.P. Moynihan, H.C. Ardley, Ulrike A. Nuber, Stephen A. Rose, Pamela F. Jones, Alexander F. Markham, Martin Scheffner, Philip Alan Robinson · 1999 · Journal of Biological Chemistry
  49. UBE4B promotes Hdm2-mediated degradation of the tumor suppressor p53
    Hong Wu, Scott L. Pomeroy, Manuel Ferreira, Natalia Teider, Juliana Mariani, Keiichi I. Nakayama, Shigetsugu Hatakeyama, Victor A. Tron, Linda F. Saltibus, Leo Spyracopoulos et al. · 2011 · Nature Medicine
  50. The antiangiogenic agent TNP-470 requires p53 and p21 CIP/WAF for endothelial cell growth arrest
    Jing-Ruey Joanna Yeh, Royce Mohan, Craig M. Crews · 2000 · Proceedings of the National Academy of Sciences
  51. A Small-Molecule Inhibitor of MDMX Activates p53 and Induces Apoptosis
    Wang, Hongbo, Ma, Xujun, Ren, Shumei, Buolamwini, John K., Yan, Chunhong · 2011 · Molecular Cancer Therapeutics
  52. The nucleolus as a fundamental regulator of the p53 response and a new target for cancer therapy
    Simone J. Woods, Katherine M. Hannan, Richard B. Pearson, Ross D. Hannan · 2014 · Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms
  53. Potential applications of MEG3 in cancer diagnosis and prognosis
    Yuqing He, Yanhong Luo, Biyu Liang, Lei Ye, Guangxing Lu, Weiming He · 2017 · Oncotarget
  54. Anastasis: recovery from the brink of cell death
    Ho Man Tang, Ho Lam Tang · 2018 · Royal Society Open Science
  55. Loss of the ARF tumor suppressor reverses premature replicative arrest but not radiation hypersensitivity arising from disabled atm function.
    Takehiko Kamijo, Esther H. van de Kamp, Miriam J. Chong, Frédérique Zindy, John Alan Diehl, Charles J. Sherr, Peter J. McKinnon · 1999 · PubMed
  56. Adenovirus and cell cycle control
    Haggit Ben-Israel · 2002 · Frontiers in bioscience
  57. Body language: the function of PML nuclear bodies in apoptosis regulation
    Thomas G. Hofmann, Hans Will · 2003 · Cell Death and Differentiation
  58. p53 associates with and targets ΔNp63 into a protein degradation pathway
    Edward A. Ratovitski, Meera Patturajan, Kenji Hibi, Barry Trink, Kengo Yamaguchi, David Sidransky · 2001 · Proceedings of the National Academy of Sciences
  59. The Sequence Alteration Associated with a Mutational Hotspot in p53 Protects Cells From Lysis by Cytotoxic T Lymphocytes Specific for a Flanking Peptide Epitope
    Matthias Theobald, Thomas Ruppert, Ulrike Kuckelkorn, Javier Hernández, Annett Häußler, Edite Antunes Ferreira, Ulrike Liewer, J Biggs, Arnold J. Levine, Christoph Huber et al. · 1998 · The Journal of Experimental Medicine
  60. Oscillations and temporal signalling in cells
    Guido Tiana, S Krishna, Simone Pigolotti A, M H Jensen, Kim Sneppen · 2007 · Physical Biology
  61. The Conformationally Flexible S9–S10 Linker Region in the Core Domain of p53 Contains a Novel MDM2 Binding Site Whose Mutation Increases Ubiquitination of p53 in Vivo
    Harumi Shimizu, Lindsay R. Burch, Amanda J Smith, David Dornan, Maura Wallace, Kathryn L. Ball, Ted R. Hupp · 2002 · Journal of Biological Chemistry
  62. The structure and dynamics of ring chromosomes in human neoplastic and non-neoplastic cells
    David Gisselsson, Mattias Höglund, Fredrik Mertens, Bertil Johansson, Paola Dal Cin, Herman VAN DEN BERGHE, William C. Earnshaw, Felix Mitelman, Nils Mandahl · 1999 · Human Genetics
  63. Comprehensive Mapping of p53 Pathway Alterations Reveals an Apparent Role for Both SNP309 and MDM2 Amplification in Sarcomagenesis
    Ito, Moriko, Barys, Louise, O'Reilly, Terence, Young, Sophie, Gorbatcheva, Bella, Monahan, John, Zumstein-Mecker, Sabine, Choong, Peter F., Dickinson, Ian, Crowe, Philip et al. · 2011 · Clinical Cancer Research
  64. Inhibition of Casein kinase-2 induces p53-dependent cell cycle arrest and sensitizes glioblastoma cells to tumor necrosis factor (TNFα)-induced apoptosis through SIRT1 inhibition
    Deobrat Dixit, Vivek Sharma, Sourish Ghosh, V. S. Mehta, Ellora Sen · 2012 · Cell Death and Disease
  65. WDR5 Supports an N-Myc Transcriptional Complex That Drives a Protumorigenic Gene Expression Signature in Neuroblastoma
    Yuting Sun, Jessica Lilian Bell, Daniel R. Carter, Samuele Gherardi, Rebecca C. Poulos, Giorgio Milazzo, Jason W.H. Wong, Rima Al‐awar, Andrew E. Tee, Pei Yan Liu et al. · 2015 · Cancer Research
  66. The proteasome as a druggable target with multiple therapeutic potentialities: Cutting and non-cutting edges
    Grazia Raffaella Tundo, Diego Sbardella, Anna Maria Santoro, Andrea Coletta, Francesco Oddone, Giuseppe Grasso, Danilo Milardi, Pedro Miguel Lacal, Stefano Marini, Roberto Purrello et al. · 2020 · Pharmacology & Therapeutics
  67. MdmX Protein Is Essential for Mdm2 Protein-mediated p53 Polyubiquitination
    Xinjiang Wang, Junru Wang, Xuejun Jiang · 2011 · Journal of Biological Chemistry
  68. Recruitment of ATM Protein to Double Strand DNA Irradiated with Ionizing Radiation
    Keiji Suzuki, Seiji Kodama, Masami Watanabe · 1999 · Journal of Biological Chemistry
  69. Human papillomavirus type 16 E6 and E7 oncogenes abrogate radiation-induced DNA damage responses in vivo through p53-dependent and p53-independent pathways
    Shiyu Song, Gene A. Gulliver, Paul F. Lambert · 1998 · Proceedings of the National Academy of Sciences
  70. Explaining oscillations and variability in the p53-Mdm2 system
    Carole J. Proctor, Douglas A. Gray · 2008 · BMC Systems Biology
  71. The genetics of transitional cell carcinoma: progress and potential clinical application
    Margaret A. Knowles · 1999 · British Journal of Urology
  72. Cells Degrade a Novel Inhibitor of Differentiation with E1A-Like Properties upon Exiting the Cell Cycle
    Miyake, Satoshi, Sellers, William R., Safran, Michal, Li, Xiaotong, Zhao, Wenqing, Grossman, Steven R., Gan, Jianmin, DeCaprio, James A., Adams, Peter D., Kaelin, William G. · 2000 · Molecular and Cellular Biology
  73. Antiproliferative Effects of CDK4/6 Inhibition in CDK4 -Amplified Human Liposarcoma In Vitro and In Vivo
    Zhang, Yi-Xiang, Sicinska, Ewa, Czaplinski, Jeffrey T., Remillard, Stephen P., Moss, Samuel, Wang, Yuchuan, Brain, Christopher, Loo, Alice, Snyder, Eric L., Demetri, George D. et al. · 2014 · Molecular Cancer Therapeutics
  74. Germline SDHx variants modify breast and thyroid cancer risks in Cowden and Cowden-like syndrome via FAD/NAD-dependant destabilization of p53
    Ying Ni, Xin He, Jinlian Chen, Jessica Moline, Jessica L. Mester, Mohammed S. Orloff, Matthew David Ringel, Charis Eng · 2011 · Human Molecular Genetics
  75. Proteasome‐mediated turnover of the transcriptional activator FIT is required for plant iron‐deficiency responses
    Alicia B. Sivitz, Claudia Grinvalds, Marie Barberon, Catherine Curie, Grégory Vert · 2011 · The Plant Journal
  76. Recognition of Client Proteins by the Proteasome
    Houqing Yu, Andreas T. Matouschek · 2017 · Annual Review of Biophysics
  77. A Novel MDMX Transcript Expressed in a Variety of Transformed Cell Lines Encodes a Truncated Protein with Potent p53 Repressive Activity
    Ravikumar Rallapalli, Gordon D. Strachan, Brian Cho, W. Edward Mercer, David J. Hall · 1999 · Journal of Biological Chemistry
  78. 14‐3‐3γ binds to MDMX that is phosphorylated by UV‐activated Chk1, resulting in p53 activation
    Yetao Jin, Mu‐Shui Dai, Steven Z. Lu, Yingda Xu, Zhijun Luo, Yingming Zhao, Hua Lu · 2006 · The EMBO Journal
  79. HIV-1 viral infectivity factor interacts with TP53 to induce G2 cell cycle arrest and positively regulate viral replication
    Taisuke Izumi, Katsuhiro Io, Masashi Matsui, Kotaro Shirakawa, Masanobu Shinohara, Yuya Nagai, Masahiro Kawahara, Masayuki Kobayashi, Hiroshi Kondoh, Naoko Misawa et al. · 2010 · Proceedings of the National Academy of Sciences
  80. Regulation of p53 Nuclear Export through Sequential Changes in Conformation and Ubiquitination
    Linghu Nie, Mark M. Sasaki, Carl G. Maki · 2007 · Journal of Biological Chemistry
  81. Tissue-specific alternative splicing in the human INK4a/ARF cell cycle regulatory locus
    Keith D. Robertson, Peter A. Jones · 1999 · Oncogene
  82. A peptide fragment of azurin induces a p53-mediated cell cycle arrest in human breast cancer cells
    Tohru Yamada, Rajeshwari R. Mehta, Fatima Lekmine, Konstantin T. Christov, Marissa L. King, Dibyen Majumdar, Anne L. Shilkaitis, Albert Green, Laura Bratescu, Craig W. Beattie et al. · 2009 · Molecular Cancer Therapeutics
  83. Epstein-Barr Virus Nuclear Antigen 3C Augments Mdm2-Mediated p53 Ubiquitination and Degradation by Deubiquitinating Mdm2
    Abhik Saha, Masanao Murakami, Pankaj Kumar, Bharat G. Bajaj, Karen Sims, Erle S. Robertson · 2009 · Journal of Virology
  84. Regulation of the p53 protein by the MDM2 oncoprotein--thirty-eighth G.H.A. Clowes Memorial Award Lecture.
    Deborah A. Freedman, Arnold J. Levine · 1999 · PubMed
  85. Oscillations and bistability in the stochastic model of p53 regulation
    Krzysztof Puszyński, Beata Hat, Tomasz Lipniacki B · 2008 · Journal of Theoretical Biology
  86. The Fbw7 and BetaTRCP E3 ubiquitin ligases and their roles in tumorigenesis
    Alan, W Lau · 2012 · Frontiers in bioscience
  87. The Nedd4-binding partner 1 (N4BP1) protein is an inhibitor of the E3 ligase Itch
    Andrew Oberst, Martina Malatesta, Rami I. Aqeilan, Mario Rossi, Paolo Salomoni, Rodolfo Murillas, Prashant Sharma, Michael R. Kuehn, Moshe Oren, Carlo Maria Croce et al. · 2007 · Proceedings of the National Academy of Sciences
  88. Expression of p53 and p53/47 are controlled by alternative mechanisms of messenger RNA translation initiation
    Marco M. Candeias, Darren J. Powell, Eva Roubalová, Sébastien Apcher, Karima Bourougaa, Bořivoj Vojtěšek, Heriberto Bruzzoni‐Giovanelli, Robin Fåhræus · 2006 · Oncogene
  89. Critical Role for a Central Part of Mdm2 in the Ubiquitylation of p53
    Erik Meulmeester, Ruth Frenk, Robert Kees Stad, Petra de Graaf, Jean‐Christophe Marine, Karen H. Vousden, Aart G. Jochemsen · 2003 · Molecular and Cellular Biology
  90. p53 mediated death of cells overexpressing MDM2 by an inhibitor of MDM2 interaction with p53
    Christine Wasylyk, Roberto Salvi, Manuela Argentini, Christine Dureuil, Isabelle Delumeau, Joseph Abecassis, Laurent Debüssche, Bohdan Wasylyk · 1999 · Oncogene
  91. The E-cadherin/epidermal growth factor receptor interaction: a hypothesis of reciprocal and reversible control of intercellular adhesion and cell proliferation
    Aida U. Jawhari, Michael J.G. Farthing, Massimo Pignatelli · 1999 · The Journal of Pathology
  92. Insulin-Like Growth Factor-1 Induces Mdm2 and Down-Regulates p53, Attenuating the Myocyte Renin-Angiotensin System and Stretch-Mediated Apoptosis
    Annarosa Leri, Yu Liu, Pier Paolo Claudio, Jan Kajstura, Xiaowei Wang, Shenglun Wang, Parminder Kang, Ashwani Malhotra, Piero Anversa · 1999 · American Journal Of Pathology
  93. Mdm2 and MdmX partner to regulate p53
    Xinjiang Wang, Xuejun Jiang · 2012 · FEBS Letters
  94. p53 and autophagy in cancer: Guardian of the genome meets guardian of the proteome
    Kevin M. Ryan · 2010 · European Journal of Cancer
  95. p53 stability is regulated by diverse deubiquitinating enzymes
    Seul‐Ki Kwon, Madhuri Saindane, Kwang‐Hyun Baek · 2017 · Biochimica et Biophysica Acta (BBA) - Reviews on Cancer
  96. Crosstalk between p53 and TGF- β Signalling
    Rebecca Elston, Gareth J. Inman · 2012 · Journal of Signal Transduction
  97. Regulation of p53 Stability and Function in HCT116 Colon Cancer Cells
    Matthias D. Kaeser, Stephanie Kaeser-Pebernard, Richard D Iggo · 2004 · Journal of Biological Chemistry
  98. Myc-ARF (Alternate Reading Frame) Interaction Inhibits the Functions of Myc
    Abhishek Datta, Alo Nag, Wei Pan, Nissim Hay, Andrei L. Gartel, Oscar R. Colamonici, Yasuji Mori, Pradip Raychaudhuri · 2004 · Journal of Biological Chemistry
  99. E2F1 Induces Phosphorylation of p53 That Is Coincident with p53 Accumulation and Apoptosis
    Harry A. Rogoff, Mary Pickering, Michelle E. Debatis, Stephen N. Jones, Timothy F. Kowalik · 2002 · Molecular and Cellular Biology
  100. Natural products targeting the p53-MDM2 pathway and mutant p53: Recent advances and implications in cancer medicine
    Jiang‐Jiang Qin, Xin Li, Courtney Hunt, Wei Wang, Hui Wang, Ruiwen Zhang · 2018 · Genes & Diseases