An agenda for personalized medicine

Incidence of Adverse Drug Reactions in Hospitalized Patients: A Meta-analysis of Prospective Studies

Lazarou, J., Pomeranz, B. H., & Corey, P. N. (1998) · JAMA · doi:10.1001/jama.279.15.1200 · Cited by 4,807 · see citing works

Adverse drug reactions as cause of admission to hospital: prospective analysis of 18 820 patients

Pirmohamed, M., James, S., Meakin, S., Green, C. A., SCOTT, A. K., Walley, T. J., Farrar, K., Park, B. K., & Breckenridge, A. M. (2004) · BMJ · doi:10.1136/bmj.329.7456.15 · Cited by 3,236 · see citing works

Coeliac Disease

Holmes, G. K. T., & Cooke, W. T. (1984) · Cited by 2,638 · see citing works

Systematic meta-analyses of Alzheimer disease genetic association studies: the AlzGene database

Bertram, L., McQueen, M. B., Mullin, K., Blacker, D., & Tanzi, R. E. (2007) · Nature Genetics · doi:10.1038/ng1934 · Cited by 1,857 · see citing works

The NCBI dbGaP database of genotypes and phenotypes

Mailman, M., Feolo, M., Jin, Y., Kimura, M., Tryka, K., Bagoutdinov, R., Hao, L., Kiang, A., Paschall, J., Phan, L., et al. (2007) · Nature Genetics · doi:10.1038/ng1007-1181 · Cited by 1,122 · see citing works

Human genetic variation and its contribution to complex traits

Frazer, K. A., Murray, S. S., Schork, N. J., & Topol, E. J. (2009) · Nature Reviews Genetics · doi:10.1038/nrg2554 · Cited by 1,073 · see citing works

Clinical risk factors, DNA variants, and the development of type 2 diabetes

Lyssenko, V., Jonsson, A., Almgren, P., Pulizzi, N., Isomaa, B., Tuomi, T., Berglund, G., Altshuler, D., Nilsson, P., & Groop, L. (2008) · New England Journal of Medicine · doi:10.1056/nejmoa0801869 · Cited by 938 · see citing works

Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts

Aulchenko, Y. S., Janssens, A. C. J. W., Albert Hofman, D., Isaacs, A. J., Sijbrands, E. J. G., Witteman, J. C. M., van Duijn, C. M., Ripatti, S., Lindqvist, I., Perola, M., et al. (2008) · Nature Genetics · doi:10.1038/ng.269 · Cited by 846 · see citing works

Genotype score in addition to common risk factors for prediction of type 2 diabetes

Meigs, J. B., Shrader, P., Sullivan, L. M., McAteer, J. B., Fox, C. S., Dupuis, J., Manning, A. K., Florez, J. C., Wilson, P. W. F., D'Agostino, R. B., et al. (2008) · New England Journal of Medicine · doi:10.1056/nejmoa0804742 · Cited by 759 · see citing works

Coeliac disease

Green, P. H., & Jabrì, B. (2003) · The Lancet · doi:10.1016/s0140-6736(03)14027-5 · Cited by 730 · see citing works

Newly identified genetic risk variants for celiac disease related to the immune response

Hunt, K. A., Zhernakova, A., Turner, G., Heap, G., Franke, L., Bruinenberg, M., Romanos, J., Dinesen, L. C., Ryan, A. W., Panesar, D., et al. (2008) · Nature Genetics · doi:10.1038/ng.102 · Cited by 675 · see citing works

A Genome-Wide Association Study of Psoriasis and Psoriatic Arthritis Identifies New Disease Loci

Liu, Y., Helms, C. A., Liao, W. J., Zaba, L. C., Duan, S., Gardner, J. M., Wise, C. A., Miner, A. G., Malloy, M. J., Pullinger, C. R., et al. (2008) · PLoS Genetics · doi:10.1371/journal.pgen.1000041 · Cited by 660 · see citing works

A Systematic Genetic Assessment of 1,433 Sequence Variants of Unknown Clinical Significance in the BRCA1 and BRCA2 Breast Cancer–Predisposition Genes

Easton, D. F., Deffenbaugh, A. M., Pruss, D., Frye, C., Wenstrup, R. J., Allen-Brady, K., Tavtigian, S. V., Monteiro, A. N. A., Iversen, E. S., Couch, F. J., et al. (2007) · The American Journal of Human Genetics · doi:10.1086/521032 · Cited by 455 · see citing works

A systematic review of perceived risks, psychological and behavioral impacts of genetic testing

Heshka, J., Palleschi, C., Howley, H. E. A., Wilson, B. J., & Wells, P. S. (2008) · Genetics in Medicine · doi:10.1097/gim.0b013e31815f524f · Cited by 327 · see citing works

The Current Landscape for Direct-to-Consumer Genetic Testing: Legal, Ethical, and Policy Issues

Hogarth, S., Javitt, G. H., & Melzer, D. R. (2008) · Annual Review of Genomics and Human Genetics · doi:10.1146/annurev.genom.9.081307.164319 · Cited by 268 · see citing works

Genetic Variants Associated with Complex Human Diseases Show Wide Variation across Multiple Populations

Adeyemo, A., & Rotimi, C. N. (2009) · Public Health Genomics · doi:10.1159/000218711 · Cited by 171 · see citing works

PharmGKB: Understanding the Effects of Individual Genetic Variants

Sangkuhl, K., Berlin, D. S., Altman, R. B., & Klein, T. E. (2008) · Drug Metabolism Reviews · doi:10.1080/03602530802413338 · Cited by 97 · see citing works

Misdirected precaution

Prainsack, B., Reardon, J., Hindmarsh, R., Gottweis, H., Naue, U., & Lunshof, J. E. (2008) · Nature · doi:10.1038/456034a · Cited by 97 · see citing works

The Genomics Gold Rush

Topol, E. J., Murray, S. S., & Frazer, K. A. (2007) · JAMA · doi:10.1001/jama.298.2.218 · Cited by 75 · see citing works

Experimental Man: What One Man's Body Reveals about His Future, Your Health, and Our Toxic World

Duncan, D. E. (2009) · Medical Entomology and Zoology · Cited by 33 · see citing works

American Society of Clinical Oncology Policy Statement Update: Genetic and Genomic Testing for Cancer Susceptibility

Robson, M. E., Bradbury, A. R., Arun, B., Domchek, S. M., Ford, J. M., Hampel, H. L., Lipkin, S. M., Syngal, S., Wollins, D. S., & Lindor, N. M. (2015) · Journal of Clinical Oncology · doi:10.1200/jco.2015.63.0996 · Cited by 939 · see citing works

The impact of next-generation sequencing on genomics

Zhang, J., Chiodini, R., Badr, A., & Zhang, G. (2011) · Journal of Genetics and Genomics · doi:10.1016/j.jgg.2011.02.003 · Cited by 577 · see citing works

Effect of Direct-to-Consumer Genomewide Profiling to Assess Disease Risk

Bloss, C. S., Schork, N. J., & Topol, E. J. (2011) · New England Journal of Medicine · doi:10.1056/nejmoa1011893 · Cited by 565 · see citing works

Intellectual Property Rights and Innovation: Evidence from the Human Genome

Williams, H. (2013) · Journal of Political Economy · doi:10.1086/669706 · Cited by 496 · see citing works

Deploying whole genome sequencing in clinical practice and public health: Meeting the challenge one bin at a time

Berg, J. S., Khoury, M. J., & Evans, J. P. (2011) · Genetics in Medicine · doi:10.1097/gim.0b013e318220aaba · Cited by 489 · see citing works

Genetics of Inflammatory Bowel Diseases

McGovern, D. P. B., Kugathasan, S., & Cho, J. H. (2015) · Gastroenterology · doi:10.1053/j.gastro.2015.08.001 · Cited by 428 · see citing works

American Society of Clinical Oncology Policy Statement Update: Genetic and Genomic Testing for Cancer Susceptibility

Robson, M. E., Storm, C. D., Weitzel, J. N., Wollins, D. S., & Offit, K. (2010) · Journal of Clinical Oncology · doi:10.1200/jco.2009.27.0660 · Cited by 421 · see citing works

Towards a comprehensive structural variation map of an individual human genome

Pang, A. W., MacDonald, J. R., Pinto, D., Wei, J., Rafiq, M. A., Conrad, D. F., Park, H., Hurles, M. E., Lee, C., Venter, J. C., et al. (2010) · Genome Biology · doi:10.1186/gb-2010-11-5-r52 · Cited by 335 · see citing works

Nutrigenetics and Nutrigenomics: Viewpoints on the Current Status and Applications in Nutrition Research and Practice

Fenech, M. F., El‐Sohemy, A., Cahill, L. E., Ferguson, L. R., French, T.-A. C., Tai, E. S., Milner, J. A., Koh, W., Xie, L. Y., Zucker, M., et al. (2011) · Lifestyle Genomics · doi:10.1159/000327772 · Cited by 359 · see citing works

Graphene-Based Sensors for Human Health Monitoring

Huang, H., Su, S., Wu, N., Wan, H., Wan, S., Bi, H., & Sun, L. (2019) · Frontiers in Chemistry · doi:10.3389/fchem.2019.00399 · Cited by 336 · see citing works

The molecular pathology of cancer

Harris, T., & McCormick, F. P. (2010) · Nature Reviews Clinical Oncology · doi:10.1038/nrclinonc.2010.41 · Cited by 278 · see citing works

Personality and Longevity: Knowns, Unknowns, and Implications for Public Health and Personalized Medicine

Chapman, B. P., Roberts, B., & Duberstein, P. (2011) · Journal of Aging Research · doi:10.4061/2011/759170 · Cited by 283 · see citing works

Genetics, genomics, and cancer risk assessment

Weitzel, J. N., Blazer, K. R., MacDonald, D. J., Culver, J. O., & Offit, K. (2011) · CA A Cancer Journal for Clinicians · doi:10.3322/caac.20128 · Cited by 250 · see citing works

CRISPR Mediated Biosensing Toward Understanding Cellular Biology and Point‐of‐Care Diagnosis

Dai, Y., Wu, Y., Liu, G., & Gooding, J. J. (2020) · Angewandte Chemie International Edition · doi:10.1002/anie.202005398 · Cited by 243 · see citing works

The Emergence of Translational Epidemiology: From Scientific Discovery to Population Health Impact

Khoury, M. J., GWINN, M. L., & Ioannidis, J. P. A. (2010) · American Journal of Epidemiology · doi:10.1093/aje/kwq211 · Cited by 240 · see citing works

The Brain-to-Brain Loop Concept for Laboratory Testing 40 Years After Its Introduction

Plebani, M., Laposata, M., & Lundberg, G. D. (2011) · American Journal of Clinical Pathology · doi:10.1309/ajcpr28hwhssdnon · Cited by 217 · see citing works

Personalizing medicine with clinical pharmacogenetics

Scott, S. A. (2011) · Genetics in Medicine · doi:10.1097/gim.0b013e318238b38c · Cited by 211 · see citing works

Use of HLA-B*58:01 genotyping to prevent allopurinol induced severe cutaneous adverse reactions in Taiwan: national prospective cohort study

Ko, T.-M., Tsai, C., Chen, S.-Y., Chen, K.-S., Yu, K., Chu, C., Huang, C.-M., Wang, C., Weng, C., Yu, C.-L., et al. (2015) · BMJ · doi:10.1136/bmj.h4848 · Cited by 209 · see citing works

Personalized medicine: new genomics, old lessons

Offit, K. (2011) · Human Genetics · doi:10.1007/s00439-011-1028-3 · Cited by 204 · see citing works

A review of flexible force sensors for human health monitoring

Cheng, M., Zhu, G., Zhang, F., Tang, W., Jianping, S., Yang, J., & Zhu, L. (2020) · Journal of Advanced Research · doi:10.1016/j.jare.2020.07.001 · Cited by 203 · see citing works

Surpassing the detection limit and accuracy of the electrochemical DNA sensor through the application of CRISPR Cas systems

Xu, W., Jin, T., Dai, Y., & Liu, C.-C. (2020) · Biosensors and Bioelectronics · doi:10.1016/j.bios.2020.112100 · Cited by 191 · see citing works

Risky Business: Risk Perception and the Use of Medical Services among Customers of DTC Personal Genetic Testing

Kaufman, D., Bollinger, J. M., Dvoskin, R. L., & Scott, J. A. (2012) · Journal of Genetic Counseling · doi:10.1007/s10897-012-9483-0 · Cited by 180 · see citing works

Motivations and Perceptions of Early Adopters of Personalized Genomics: Perspectives from Research Participants

Gollust, S. E., Gordon, E. S., Zayac, C., Griffin, G., Christman, M. F., Pyeritz, R. E., Wawak, L., & Bernhardt, B. A. (2011) · Public Health Genomics · doi:10.1159/000327296 · Cited by 174 · see citing works

Cardiovascular disease: The rise of the genetic risk score

Knowles, J. W., & Ashley, E. A. (2018) · PLOS Medicine · doi:10.1371/journal.pmed.1002546 · Cited by 182 · see citing works

An informatics approach to analyzing the incidentalome

Berg, J., Adams, M. C., Nassar, N., Bizon, C., Lee, K., Schmitt, C., Wilhelmsen, K., & Evans, J. P. (2012) · Genetics in Medicine · doi:10.1038/gim.2012.112 · Cited by 175 · see citing works

Direct-to-consumer genetic testing

Horton, R., Crawford, G., Freeman, L., Fenwick, A., Wright, C. F., & Lucassen, A. (2019) · BMJ · doi:10.1136/bmj.l5688 · Cited by 151 · see citing works

Theranostic barcoded nanoparticles for personalized cancer medicine

Yaari, Z. A., da Silva, D., Zinger, A., Goldman, E., Kajal, A., Tshuva, R., Barak, E., Dahan, N., Hershkovitz, D., Goldfeder, M., et al. (2016) · Nature Communications · doi:10.1038/ncomms13325 · Cited by 147 · see citing works

New Approaches to Molecular Diagnosis

Korf, B. R., & Rehm, H. L. (2013) · JAMA · doi:10.1001/jama.2013.3239 · Cited by 143 · see citing works

Integrative phenomics reveals insight into the structure of phenotypic diversity in budding yeastPreprint

Skelly, D. A., Merrihew, G. E., Riffle, M. E., Connelly, C. F., Kerr, E. O., Johansson, M., Jaschob, D., Graczyk, B., Shulman, N., Wakefield, J., et al. (2013) · Genome Research · doi:10.1101/gr.155762.113 · Cited by 140 · see citing works

Impact of direct-to-consumer genomic testing at long term follow-up

Bloss, C. S., Wineinger, N. E., Darst, B. F., Schork, N. J., & Topol, E. J. (2013) · Journal of Medical Genetics · doi:10.1136/jmedgenet-2012-101207 · Cited by 137 · see citing works

Internet-Based Direct-to-Consumer Genetic Testing: A Systematic Review

Covolo, L., Rubinelli, S., Ceretti, E., & Gelatti, U. (2015) · Journal of Medical Internet Research · doi:10.2196/jmir.4378 · Cited by 132 · see citing works

Primary care providers’ cancer genetic testing-related knowledge, attitudes, and communication behaviors: A systematic review and research agenda

Hamilton, J. G., Abdiwahab, E., Edwards, H. M., Fang, M.-L. E., Jdayani, A., & Breslau, E. S. (2016) · Journal of General Internal Medicine · doi:10.1007/s11606-016-3943-4 · Cited by 130 · see citing works

Examining moderation analyses in propensity score methods: Application to depression and substance use.

Green, K. M., & Stuart, E. A. (2014) · Journal of Consulting and Clinical Psychology · doi:10.1037/a0036515 · Cited by 127 · see citing works

Consumer perceptions of direct-to-consumer personalized genomic risk assessments

Bloss, C. S., Ornowski, L., Silver, E., Cargill, M., Vanier, V., Schork, N. J., & Topol, E. J. (2010) · Genetics in Medicine · doi:10.1097/gim.0b013e3181eb51c6 · Cited by 122 · see citing works

Future perspectives of personalized medicine in traditional Chinese medicine: A systems biology approach

Zhang, A., Sun, H. J., Wang, P., Han, Y., & Wang, X. (2011) · Complementary Therapies in Medicine · doi:10.1016/j.ctim.2011.10.007 · Cited by 121 · see citing works

Hot melt extrusion paired fused deposition modeling 3D printing to develop hydroxypropyl cellulose based floating tablets of cinnarizine

Vo, A. Q., Zhang, J., Nyavanandi, D., Bandari, S., & Repka, M. A. (2020) · Carbohydrate Polymers · doi:10.1016/j.carbpol.2020.116519 · Cited by 118 · see citing works

Informational content, literacy demands, and usability of websites offering health-related genetic tests directly to consumers

Lachance, C. R., Erby, L. H., Ford, B. M., Allen, V. C., & Kaphingst, K. A. (2010) · Genetics in Medicine · doi:10.1097/gim.0b013e3181dbd8b2 · Cited by 112 · see citing works

Taxonomizing, sizing, and overcoming the incidentalome

Kohane, I. S., Hsing, M., & Kong, S. W. (2012) · Genetics in Medicine · doi:10.1038/gim.2011.68 · Cited by 112 · see citing works

A Survey of UK Public Interest in Internet-Based Personal Genome Testing

Cherkas, L. F., Harris, J. M., Levinson, E., Spector, T. D., & Prainsack, B. (2010) · PLoS ONE · doi:10.1371/journal.pone.0013473 · Cited by 109 · see citing works

Genetic testing and common disorders in a public health framework: how to assess relevance and possibilities

Becker, F., van El, C. G., Ibarreta, D., Zika, E., Hogarth, S., Borry, P., Cambon‐Thomsen, A., Cassiman, J. J., Evers‐Kiebooms, G., Hodgson, S. V., et al. (2011) · European Journal of Human Genetics · doi:10.1038/ejhg.2010.249 · Cited by 110 · see citing works

Using Bayesian networks to discover relations between genes, environment, and disease

Su, C., Andrew, A. S., Karagas, M. R., & Borsuk, M. E. (2013) · BioData Mining · doi:10.1186/1756-0381-6-6 · Cited by 105 · see citing works

Implementation and utilization of genetic testing in personalized medicine

Scott, S., Abul-Husn, N., Owusu Obeng, A., Sanderson, S., & Gottesman, O. (2014) · Pharmacogenomics and Personalized Medicine · doi:10.2147/pgpm.s48887 · Cited by 106 · see citing works

Direct-to-consumer genomic testing: systematic review of the literature on user perspectives

Goldsmith, L., Jackson, L. M., O’Connor, A., & Skirton, H. (2012) · European Journal of Human Genetics · doi:10.1038/ejhg.2012.18 · Cited by 95 · see citing works

Enterprising or altruistic selves? Making up research subjects in genetics research

Tutton, R., & Prainsack, B. (2011) · Sociology of Health & Illness · doi:10.1111/j.1467-9566.2011.01348.x · Cited by 90 · see citing works

Genetic variation in IBD: progress, clues to pathogenesis and possible clinical utility

Ye, B. D., & McGovern, D. P. B. (2016) · Expert Review of Clinical Immunology · doi:10.1080/1744666x.2016.1184972 · Cited by 89 · see citing works

Direct-to-consumer personalized genomic testing

Bloss, C. S., Darst, B. F., Topol, E. J., & Schork, N. J. (2011) · Human Molecular Genetics · doi:10.1093/hmg/ddr349 · Cited by 87 · see citing works

Identifiability in biobanks: models, measures, and mitigation strategies

Malin, B., Loukides, G., Benitez, K., & Clayton, E. W. (2011) · Human Genetics · doi:10.1007/s00439-011-1042-5 · Cited by 84 · see citing works

Emerging technologies for hybridization based single nucleotide polymorphism detection

Knez, K., Spasić, D., Janssen, K. P. F., & Lammertyn, J. (2013) · The Analyst · doi:10.1039/c3an01436c · Cited by 76 · see citing works

Uplift Random Forests

Guelman, L., Guillén, M., & Marín, A. M. P. (2015) · Cybernetics & Systems · doi:10.1080/01969722.2015.1012892 · Cited by 75 · see citing works

Predicting phenotypic variation in yeast from individual genome sequences

Jelier, R., Semple, J. I., García-Verdugo, R., & Lehner, B. (2011) · Nature Genetics · doi:10.1038/ng.1007 · Cited by 73 · see citing works

Genetics of muscle strength and power: Polygenic profile similarity limits skeletal muscle performance

Hughes, D. C., Day, S. H., Ahmetov, I. I., & Williams, A. G. (2011) · Journal of Sports Sciences · doi:10.1080/02640414.2011.597773 · Cited by 70 · see citing works

Bioinformatics for personal genome interpretation

Capriotti, E., Nehrt, N. L., Kann, M. G., & Bromberg, Y. (2012) · Briefings in Bioinformatics · doi:10.1093/bib/bbr070 · Cited by 68 · see citing works

Systems Biology Technologies Enable Personalized Traditional Chinese Medicine: A Systematic Review

Wang, X., Zhang, A., Sun, H. J., & Wang, P. (2012) · The American Journal of Chinese Medicine · doi:10.1142/s0192415x12500826 · Cited by 66 · see citing works

Genomic Medicine: New Frontiers and New Challenges

Pasic, M. D., Samaan, S. F., & Yousef, G. M. (2013) · Clinical Chemistry · doi:10.1373/clinchem.2012.184622 · Cited by 66 · see citing works

Personal genomics: information can be harmful

Ransohoff, D. F., & Khoury, M. J. (2009) · European Journal of Clinical Investigation · doi:10.1111/j.1365-2362.2009.02232.x · Cited by 65 · see citing works

Graphene and Its Derivatives: Synthesis and Application in the Electrochemical Detection of Analytes in Sweat

Singh, A., Ahmed, A., Sharma, A., & Arya, S. K. (2022) · Biosensors · doi:10.3390/bios12100910 · Cited by 62 · see citing works

Towards personalized care in IBD

Gerich, M. E., & McGovern, D. P. B. (2013) · Nature Reviews Gastroenterology & Hepatology · doi:10.1038/nrgastro.2013.242 · Cited by 62 · see citing works

Personalized cancer genetics training for personalized medicine: Improving community-based healthcare through a genetically literate workforce

Blazer, K. R., MacDonald, D. J., Culver, J. O., Huizenga, C. R., Morgan, R. J., Uman, G. C., & Weitzel, J. N. (2011) · Genetics in Medicine · doi:10.1097/gim.0b013e31821882b7 · Cited by 62 · see citing works

Concordance Study of 3 Direct-to-Consumer Genetic-Testing Services

Imai, K., Kricka, L. J., & Fortina, P. M. (2010) · Clinical Chemistry · doi:10.1373/clinchem.2010.158220 · Cited by 62 · see citing works

Coriell Personalized Medicine Collaborative ® : A Prospective Study of the Utility Of Personalized Medicine

Keller, M., Gordon, E. S., Stack, C. B., Gharani, N., Sill, C. J., Schmidlen, T., Mintzer, J. L., Pallies, J., Gerry, N. P., & Christman, M. F. (2010) · Personalized Medicine · doi:10.2217/pme.10.13 · Cited by 61 · see citing works

Variations in predicted risks in personal genome testing for common complex diseases

Kalf, R. R. J., Mihăescu, R., Kundu, S., de Knijff, P., Green, R. C., & Janssens, A. C. J. W. (2013) · Genetics in Medicine · doi:10.1038/gim.2013.80 · Cited by 61 · see citing works

Health-Care Referrals from Direct-to-Consumer Genetic Testing

Giovanni, M. A., Fickie, M. R., Lehmann, L. S., Green, R. C., Meckley, L. M., Veenstra, D. L., & Murray, M. F. (2010) · Genetic Testing and Molecular Biomarkers · doi:10.1089/gtmb.2010.0051 · Cited by 59 · see citing works

Genetic susceptibility testing for neurodegenerative diseases: Ethical and practice issues

Roberts, J. S., & Uhlmann, W. R. (2013) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2013.02.005 · Cited by 60 · see citing works

Genetic testing and common disorders in a public health framework

van El, C. G., & Cornel, M. C. (2011) · European Journal of Human Genetics · doi:10.1038/ejhg.2010.176 · Cited by 57 · see citing works

How do SNP ascertainment schemes and population demographics affect inferences about population history?

McTavish, E. J., & Hillis, D. M. (2015) · BMC Genomics · doi:10.1186/s12864-015-1469-5 · Cited by 54 · see citing works

The Prospect of Genome‐guided Preventive Medicine: A Need and Opportunity for Genetic Counselors

O’Daniel, J. M. (2010) · Journal of Genetic Counseling · doi:10.1007/s10897-010-9302-4 · Cited by 54 · see citing works

the Utility of Genome-Wide Association Studies in Hepatology

Karlsen, T. H., Melum, E., & Franke, A. (2010) · Hepatology · doi:10.1002/hep.23564 · Cited by 54 · see citing works

Personalised Medicine, Individual Choice and the Common Good

van Beers, B. C., Dickenson, D., & Sterckx, S. (2018) · Cambridge University Press eBooks · doi:10.1017/9781108590600 · Cited by 52 · see citing works

Bench-to-bedside: Translational development landscape of biotechnology in healthcare

Liao, C., Xiao, S., & Wang, X. (2023) · Health Sciences Review · doi:10.1016/j.hsr.2023.100097 · Cited by 52 · see citing works

Extending Comprehensive Cancer Center Expertise in Clinical Cancer Genetics and Genomics to Diverse Communities: The Power of Partnership

MacDonald, D. J., Blazer, K. R., & Weitzel, J. N. (2010) · Journal of the National Comprehensive Cancer Network · doi:10.6004/jnccn.2010.0046 · Cited by 52 · see citing works

Assessing Risk Factors as Potential Screening Tests

Wald, N., & Morris, J. K. (2010) · Archives of Internal Medicine · doi:10.1001/archinternmed.2010.378 · Cited by 50 · see citing works

Translational Bioinformatics: Linking the Molecular World to the Clinical World

Altman, R. B. (2012) · Clinical Pharmacology & Therapeutics · doi:10.1038/clpt.2012.49 · Cited by 48 · see citing works

Biological function through network topology: a survey of the human diseasome

Janjić, V., & Pržulj, N. (2012) · Briefings in Functional Genomics · doi:10.1093/bfgp/els037 · Cited by 49 · see citing works

Recent Developments of Electrochemical and Optical Biosensors for Antibody Detection

Xu, W., Wang, D., Li, D., & Liu, C.-C. (2019) · International Journal of Molecular Sciences · doi:10.3390/ijms21010134 · Cited by 47 · see citing works

Direct-to-Consumer Personal Genome Testing and Cancer Risk Prediction

Bellcross, C. A., Page, P. Z., & Meaney‐Delman, D. M. (2012) · The Cancer Journal · doi:10.1097/ppo.0b013e3182610e38 · Cited by 45 · see citing works

Public reaction to direct-to-consumer online genetic tests: Comparing attitudes, trust and intentions across commercial and conventional providers

Critchley, C. R., Nicol, D., Otlowski, M. F. A., & Chalmers, D. (2014) · Public Understanding of Science · doi:10.1177/0963662513519937 · Cited by 45 · see citing works

Cancer Risk Assessment Using Genetic Panel Testing: Considerations for Clinical Application

Hiraki, S. C., Rinella, E. S., Schnabel, F. R., Oratz, R., & D, H. O. M. (2014) · Journal of Genetic Counseling · doi:10.1007/s10897-014-9695-6 · Cited by 45 · see citing works

Translational Epidemiology in Psychiatry

Weissman, M. M., Brown, A. S., & Talati, A. (2011) · Archives of General Psychiatry · doi:10.1001/archgenpsychiatry.2011.47 · Cited by 44 · see citing works

Selective and sensitive detection and quantification of arylamine N-acetyltransferase 2 by a ratiometric fluorescence probe

Cui, L., Zhong, Y., Zhu, W. P., Xu, Y. F., & Qian, X. H. (2010) · Chemical Communications · doi:10.1039/c0cc01000f · Cited by 44 · see citing works

Advancements and applications of micro and nanostructured capacitive sensors: A review

Sakthivelpathi, V., Li, T., Qian, Z., Lee, C., Taylor, Z., & Chung, J. (2024) · Sensors and Actuators A Physical · doi:10.1016/j.sna.2024.115701 · Cited by 43 · see citing works

Family History and Personal Genomics As Tools for Improving Health in an Era of Evidence-Based Medicine

Khoury, M. J., Feero, W. G., & Valdez, R. A. (2010) · American Journal of Preventive Medicine · doi:10.1016/j.amepre.2010.03.019 · Cited by 42 · see citing works

Beyond clinical utility: The multiple values of DTC genetics

Turrini, M., & Prainsack, B. (2016) · Applied & Translational Genomics · doi:10.1016/j.atg.2016.01.008 · Cited by 42 · see citing works

Multigenic condition risk assessment in direct-to-consumer genomic services

Swan, M. (2010) · Genetics in Medicine · doi:10.1097/gim.0b013e3181d5f73b · Cited by 41 · see citing works

Genetic risk estimation in the Coriell Personalized Medicine Collaborative

Stack, C. B., Gharani, N., Gordon, E. S., Schmidlen, T., Christman, M. F., & Keller, M. (2011) · Genetics in Medicine · doi:10.1097/gim.0b013e318201164c · Cited by 41 · see citing works

Personalizing Medicine: Disease Prevention in silico and in socio

Green, S., & Vogt, H. (2016) · BIBSYS Brage (BIBSYS (Norway)) · Cited by 40 · see citing works

Functional Variants in DPYSL2 Sequence Increase Risk of Schizophrenia and Suggest a Link to mTOR Signaling

Liu, Y., Pham, X., Zhang, L., Chen, P.-L., Burzynski, G. M., McGaughey, D. M., He, S., McGrath, J. A., Wolyniec, P. S., Fallin, M. D., et al. (2014) · G3 Genes Genomes Genetics · doi:10.1534/g3.114.015636 · Cited by 40 · see citing works

Summarizing polygenic risks for complex diseases in a clinical whole-genome report

Kong, S. W., Lee, I., Leshchiner, I., Krier, J. B., Kraft, P., Rehm, H. L., Green, R. C., Kohane, I. S., & MacRae, C. A. (2014) · Genetics in Medicine · doi:10.1038/gim.2014.143 · Cited by 40 · see citing works

Bioethical and Clinical Dilemmas of Direct-to-Consumer Personal Genomic Testing: The Problem of Misattributed Equivalence

Eng, C., & Sharp, R. R. (2010) · Science Translational Medicine · doi:10.1126/scitranslmed.3000214 · Cited by 39 · see citing works

23andMe, the Food and Drug Administration, and the Future of Genetic Testing

Zettler, P. J., Sherkow, J. S., & Greely, H. T. (2014) · JAMA Internal Medicine · doi:10.1001/jamainternmed.2013.14706 · Cited by 38 · see citing works

Evaluating the accuracy of AIM panels at quantifying genome ancestry

Pardo‐Seco, J., Martinón‐Torres, F., & Salas, A. (2014) · BMC Genomics · doi:10.1186/1471-2164-15-543 · Cited by 36 · see citing works

Current State and Future Prospects of Direct-to-Consumer Pharmacogenetics

Chua, E. W., & Kennedy, M. A. (2012) · Frontiers in Pharmacology · doi:10.3389/fphar.2012.00152 · Cited by 37 · see citing works

Three-Dimensional Electrohydrodynamic Printing and Spinning of Flexible Composite Structures for Oral Multidrug Forms

Wu, S., Li, J., Mai, J., & Chang, M. (2018) · ACS Applied Materials & Interfaces · doi:10.1021/acsami.8b08880 · Cited by 37 · see citing works

Words Matter: Distinguishing "Personalized Medicine" and "Biologically Personalized Therapeutics"

Cherny, N. I., de Vries, E. G. E., Emanuel, L., Fallowfield, L. J., Francis, P. A., Gabizon, A., Piccart, M. J., Sidransky, D., Soussan‐Gutman, L., & Tziraki, C. (2014) · JNCI Journal of the National Cancer Institute · doi:10.1093/jnci/dju321 · Cited by 36 · see citing works

Genomics for Disease Treatment and Prevention

Bloss, C. S., Jeste, D. V., & Schork, N. J. (2010) · Psychiatric Clinics of North America · doi:10.1016/j.psc.2010.11.005 · Cited by 36 · see citing works

Future Challenges and Present Ethical Considerations in the Use of Personalized Nutrition Based on Genetic Advice

San-Cristóbal, R., Milagro, F. I., & Martínez, J. A. (2013) · Journal of the Academy of Nutrition and Dietetics · doi:10.1016/j.jand.2013.05.028 · Cited by 36 · see citing works

Integration of omics sciences to advance biology and medicine

Boja, E. S., Kinsinger, C. R., Rodriguez, H., & Srinivas, P. R. (2014) · Clinical Proteomics · doi:10.1186/1559-0275-11-45 · Cited by 35 · see citing works

Pharmacogenomics: The Importance of Accurate Phenotypes

Gurwitz, D., & Pirmohamed, M. (2010) · Pharmacogenomics · doi:10.2217/pgs.10.41 · Cited by 34 · see citing works

Recent omics technologies and their emerging applications for personalised medicine

Kim, D., Kim, Y., Son, N., Kang, C., & Kim, A. (2017) · IET Systems Biology · doi:10.1049/iet-syb.2016.0016 · Cited by 35 · see citing works

Genetic risk information for common diseases may indeed be already useful for prevention and early detection

Gulcher, J. R., & Stefánsson, K. (2009) · European Journal of Clinical Investigation · doi:10.1111/j.1365-2362.2009.02233.x · Cited by 33 · see citing works

Consuming genomes: scientific and social innovation in direct-to-consumer genetic testing

Curnutte, M., & Testa, G. (2012) · New Genetics and Society · doi:10.1080/14636778.2012.662032 · Cited by 33 · see citing works

Direct-to-Consum er Genetic Testing: Personalized Medicine in Evolution

Leachman, S. A., MacArthur, D. G., Angrist, M. H., Gray, S. W., Bradbury, A. R., & Vorhaus, D. B. (2011) · Cited by 4 · see citing works

Direct-to-Consumer Testing

Ferguson, L. R., & Parslow, V. R. (2019) · Elsevier eBooks · doi:10.1016/b978-0-12-804572-5.00070-7 · Cited by 4 · see citing works

Direct-to-consumer genetic testing: a revised position statement of the American College of Medical Genetics and Genomics

ACMG Board of Directors (2015) · Genetics in Medicine · doi:10.1038/gim.2015.190 · Cited by 74 · see citing works

From Personalized Medicine to Consumer-Driven Testing: An Update on Direct-To-Consumer Genetic Tests

Kirtley, M. (2013) · Dignitas Slovenian journal for human rights

Direct-to-consumer advertisement of predictive genetic tests

Ramakrishnan, S. (2010)