The role of hypoxia-inducible factors in tumorigenesis

Rankin, E B, Giaccia, A J·2008·Cell Death & Differentiation

Cited by (808)

Items 101–200 of 808

  1. Hypoxia, angiogenesis and liver fibrogenesis in the progression of chronic liver diseases
    Claudia Paternostro · 2010 · World Journal of Gastroenterology
  2. N 6 -methyladenosine is required for the hypoxic stabilization of specific mRNAs
    Nate J. Fry, Brittany A. Law, Olga Ilkayeva, Christopher L. Holley, Kyle D. Mansfield · 2017 · RNA
  3. Role of hypoxia-inducible factors (HIF) in the maintenance of stemness and malignancy of colorectal cancer
    Ramakrishna Vadde, Vemula Sarojamma, Rajeswari Jinka, Neha Merchant, Pallaval Veera Bramhachari, Ganji Purnachandra Nagaraju · 2017 · Critical Reviews in Oncology/Hematology
  4. Inflammatory interferon activates HIF-1α-mediated epithelial-to-mesenchymal transition via PI3K/AKT/mTOR pathway
    Yen-Hsiu Yeh, Ho-Fu Hsiao, Yen-Cheng Yeh, Tien-Wen Chen, Tsai‐Kun Li · 2018 · Journal of Experimental & Clinical Cancer Research
  5. The m 6 A RNA demethylase FTO is a HIF-independent synthetic lethal partner with the VHL tumor suppressor
    Yiren Xiao, Kaushik N. Thakkar, Hongjuan Zhao, James P. Broughton, Yang Li, José Antonio Seoane, Anh N. Diep, Thomas J. Metzner, Rie von Eyben, David L. Dill et al. · 2020 · Proceedings of the National Academy of Sciences
  6. Angiogenesis and Multiple Myeloma
    Nicola Giuliani, Paola Storti, Marina Bolzoni, Benedetta Dalla Palma, Sabrina Bonomini · 2011 · Cancer Microenvironment
  7. Therapeutic Delivery of siRNA Silencing HIF-1 Alpha with Micellar Nanoparticles Inhibits Hypoxic Tumor Growth
    Xi‐Qiu Liu, Menghua Xiong, Xiaoting Shu, Rui-Zhi Tang, Jun Wang · 2012 · Molecular Pharmaceutics
  8. The Role of Vitamin D in Cancer Prevention and Treatment
    Aruna V. Krishnan, Donald L. Trump, Candace S. Johnson, David Feldman · 2012 · Rheumatic Disease Clinics of North America
  9. Targeting hypoxic tumour cells to overcome metastasis
    Bennewith, Kevin L, Dedhar, Shoukat · 2011 · BMC Cancer
  10. Post-Transcriptional Control of the Hypoxic Response by RNA-Binding Proteins and MicroRNAs
    Myriam Gorospe, Kumiko Tominaga, Xue Wu, Michael Fähling, Mircea Ivan · 2011 · Frontiers in Molecular Neuroscience
  11. Hypoxia-Inducible Aryl Hydrocarbon Receptor Nuclear Translocator (ARNT) (HIF-1β): Is It a Rare Exception?
    Markus Mandl, Reinhard Depping · 2014 · Molecular Medicine
  12. Oxidative stress in carcinogenesis
    James E. Klaunig, Zemin Wang · 2017 · Current Opinion in Toxicology
  13. CDK1 stabilizes HIF-1α via direct phosphorylation of Ser668 to promote tumor growth
    Noel A. Warfel, Nathan G. Dolloff, David T. Dicker, Jozef Malysz, Wafik S. El‐Deiry · 2013 · Cell Cycle
  14. Hypoxia-inducible factor (HIF)-1α suppression in myeloma cells blocks tumoral growth in vivo inhibiting angiogenesis and bone destruction
    Paola Storti, Marina Bolzoni, Gaetano Donofrío, Irma Airoldi, Daniela Guasco, Denise Toscani, E Martella, Mirca Lazzaretti, C Mancini, Luca Agnelli et al. · 2013 · Leukemia
  15. Elimination of head and neck cancer initiating cells through targeting glucose regulated protein78 signaling
    Meng‐Ju Wu, Chia-Ing Jan, Yeou‐Guang Tsay, Yau‐Hua Yu, Chih‐Yang Huang, Shu‐Chun Lin, Chung‐Ji Liu, Yu−Syuan Chen, Jeng‐Fan Lo, Cheng-Chia Yu · 2010 · Molecular Cancer
  16. Angiogenesis and expression of PDGF ‐ C , VEGF , CD 105 and HIF ‐1α in human glioblastoma
    Carlos Clara, Suely Kazue Nagahashi Marie, J.R.W. Almeida, Alda Wakamatsu, Sueli Mieko Oba‐Shinjo, Miyuki Uno, Munro A. Neville, Sérgio Rosemberg · 2014 · Neuropathology
  17. Hypoxia Enhances Sphingosine Kinase 2 Activity and Provokes Sphingosine-1-Phosphate-Mediated Chemoresistance in A549 Lung Cancer Cells
    Steffen E. Schnitzer, Andreas Weigert, Jie Zhou, Bernhard Brüne · 2009 · Molecular Cancer Research
  18. The controversial place of vitamin C in cancer treatment
    Julien Verrax, Pedro Buc Calderón · 2008 · Biochemical Pharmacology
  19. Aminoflavone, a Ligand of the Aryl Hydrocarbon Receptor, Inhibits HIF-1α Expression in an AhR-Independent Fashion
    Terzuoli, Erika, Puppo, Maura, Rapisarda, Annamaria, Uranchimeg, Badarch, Cao, Liang, Burger, Angelika M., Ziche, Marina, Melillo, Giovanni · 2010 · Cancer Research
  20. Development of mitochondria-targeted derivatives of resveratrol
    Lucia Biasutto, Andrea Mattarei, Ester Marotta, Alice Bradaschia, Nicola Sassi A, Spiridione Garbisa, Mario Zoratti, Cristina Paradisi · 2008 · Bioorganic & Medicinal Chemistry Letters
  21. Advances in targeted therapy mainly based on signal pathways for nasopharyngeal carcinoma
    Yuanbo Kang, Weihan He, Caiping Ren, Jincheng Qiao, Qiuyong Guo, Jingyu Hu, Hongjuan Xu, Xingjun Jiang, Lei Wang · 2020 · Signal Transduction and Targeted Therapy
  22. The Role of Hypoxia in Glioblastoma Radiotherapy Resistance
    Agathe L. Chédeville, Patrícia A. Madureira · 2021 · Cancers
  23. Lipoxin A4 and Its Analogue Suppress the Tumor Growth of Transplanted H22 in Mice: The Role of Antiangiogenesis
    Ying Chen, Hua Hao, Songqing He, Lei Cai, Yongsheng Li, Shunze Hu, Duyun Ye, John R. Hoidal, Ping Wu, Xiaoping Chen · 2010 · Molecular Cancer Therapeutics
  24. Hypoxia signaling and resistance in C. elegans
    Jo Anne Powell‐Coffman · 2010 · Trends in Endocrinology and Metabolism
  25. A biology-driven approach identifies the hypoxia gene signature as a predictor of the outcome of neuroblastoma patients
    Paolo Fardin, Annalisa Barla, Sofia Mosci, Lorenzo Rosasco, Alessandro Verri, Rogier Versteeg, Huib N. Caron, Jan J. Molenaar, Ingrid Øra, Alessandra Eva et al. · 2010 · Molecular Cancer
  26. <scp>HIF</scp> 3α: the little we know
    Ravenna, Linda, Salvatori, Luisa, Russo, Matteo A. · 2016 · The FEBS Journal
  27. From signalling pathways to targeted therapies: unravelling glioblastoma’s secrets and harnessing two decades of progress
    Brittany Dewdney, Misty Rayna Jenkins, Sarah A. Best, Saskia Freytag, Krishneel Prasad, Jeff Holst, Raelene Endersby, Terrance G. Johns · 2023 · Signal Transduction and Targeted Therapy
  28. The LIMD1 protein bridges an association between the prolyl hydroxylases and VHL to repress HIF-1 activity
    Daniel E. Foxler, Katherine S. Bridge, Victoria H. James, Thomas M. Webb, Maureen Mee, Sybil C.K. Wong, Yunfeng Feng, Dumitru Constantin‐Teodosiu, Thorgunnur Eyfjord Petursdottir, Jóhannes Björnsson et al. · 2012 · Nature Cell Biology
  29. Hypoxia-mediated regulation of macrophage functions in pathophysiology
    Elena Riboldi, Chiara Porta, Sara Morlacchi, Antonella Viola, Alberto Mantovani, Antonio Sica · 2012 · International Immunology
  30. Proliferation of Immature Tumor Vessels Is a Novel Marker of Clinical Progression in Prostate Cancer
    Karsten Gravdal, OLE JOHAN HALVORSEN, Svein Andreas Haukaas, Lars A. Akslen · 2009 · Cancer Research
  31. The Akt1-eNOS Axis Illustrates the Specificity of Kinase-Substrate Relationships in Vivo
    Michael Schleicher, Jun Yu, Takahisa Murata, Berhad Derakhshan, Dmitriy N. Atochin, Li Qian, Satoshi Kashiwagi, Annarita Di Lorenzo, Kenneth D. Harrison, Paul Lee Huang et al. · 2009 · Science Signaling
  32. Nanomedicine Strategies in Conquering and Utilizing the Cancer Hypoxia Environment
    Yi Pan, Longcai Liu, Xiaozhou Mou, Yu Cai · 2023 · ACS Nano
  33. Targeting VEGF-A/VEGFR2 Y949 Signaling-Mediated Vascular Permeability Alleviates Hypoxic Pulmonary Hypertension
    Weibin Zhou, Keli Liu, Lei Zeng, Jiaqi He, Xinbo Gao, Xinyu Gu, Xun Chen, Jing Jing Li, Minghui Wang, Duoguang Wu et al. · 2022 · Circulation
  34. Emerging evidence of epithelial‐to‐mesenchymal transition in lung carcinogenesis
    Mitsuo Sato, David S. Shames, Yoshinori Hasegawa · 2012 · Respirology
  35. Sleep apnea increased incidence of primary central nervous system cancers: a nationwide cohort study
    Chen, Jin-Cherng, Hwang, Juen-Haur · 2014 · Sleep Medicine
  36. A Central Role for Hypoxic Signaling in Cartilage, Bone, and Hematopoiesis
    Rankin, Erinn B., Giaccia, Amato J., Schipani, Ernestina · 2011 · Current Osteoporosis Reports
  37. Targeting the Angiopoietin-2/Tie-2 axis in conjunction with VEGF signal interference
    Nikolett M. Biel, Dietmar W. Siemann · 2014 · Cancer Letters
  38. Up‐regulation of survivin by AKT and hypoxia‐inducible factor 1α contributes to cisplatin resistance in gastric cancer
    Xuepu Sun, Xuesong Dong, Lele Lin, Xian Li Jiang, Zheng Wei, Bo Zhai, Bo Sun, Qiang Zhang, Xiaolong Wang, Hongchi Jiang et al. · 2013 · FEBS Journal
  39. Intermittent hypoxia is an angiogenic inducer for endothelial cells: role of HIF-1
    Sébastien Toffoli, Audrey Roegiers, Olivier Féron, Martine Van Steenbrugge, Noëlle Ninane, Martine J. Raes, Carine Michiels · 2009 · Angiogenesis
  40. Hyperbaric Oxygen Potentiates Doxil Antitumor Efficacy by Promoting Tumor Penetration and Sensitizing Cancer Cells
    Xian Guo Wu, Yanhong Zhu, Wei Huang, Jingqiu Li, Bixiang Zhang, Zifu Li, Xiangliang Yang · 2018 · Advanced Science
  41. Tumor suppressor WWOX regulates glucose metabolism via HIF1α modulation
    Muhannad Abu‐Remaileh, Rami I. Aqeilan · 2014 · Cell Death and Differentiation
  42. 2-Methoxyestradiol synergizes with sorafenib to suppress hepatocellular carcinoma by simultaneously dysregulating hypoxia-inducible factor-1 and -2
    Li Ma, Guangxin Li, Huaqiang Zhu, Xuesong Dong, Dali Zhao, Xian Li Jiang, Jie Li, Haiquan Qiao, Shaobin Ni, Xueying Sun · 2014 · Cancer Letters
  43. Novel Drugs with High Efficacy against Tumor Angiogenesis
    Shiyu Qi, Shoulong Deng, Zhengxing Lian, Kun Yu · 2022 · International Journal of Molecular Sciences
  44. Hypoxia activates Wnt/β-catenin signaling by regulating the expression of BCL9 in human hepatocellular carcinoma
    Xu, Wei, Zhou, Wang, Cheng, Mo, Wang, Jing, Liu, Zhian, He, Shaohui, Luo, Xiangji, Huang, Wending, Chen, Tianrui, Yan, Wangjun et al. · 2017 · Scientific Reports
  45. Stanniocalcin-2 promotes epithelial–mesenchymal transition and invasiveness in hypoxic human ovarian cancer cells
    Alice Yu Sheung Law, Chris K.C. Wong · 2010 · Experimental Cell Research
  46. In vivo Dynamics and Distinct Functions of Hypoxia in Primary Tumor Growth and Organotropic Metastasis of Breast Cancer
    Xin Lü, Carol H. Yan, Min Yuan, Yong Wei, Guohong Hu, Yibin Kang · 2010 · Cancer Research
  47. Sevoflurane promotes the expansion of glioma stem cells through activation of hypoxia-inducible factors in vitro
    Q.Y. Shi, S.J. Zhang, L. Liu, Q.S. Chen, Lina Yu, F.J. Zhang, Min Yan · 2014 · British Journal of Anaesthesia
  48. Sequential pathogenesis of metastatic VHL mutant clear cell renal cell carcinoma: putting it together with a translational perspective
    Niraj Konchady Shenoy, Lance C. Pagliaro · 2016 · Annals of Oncology
  49. Metformin increases PDH and suppresses HIF-1α under hypoxic conditions and induces cell death in oral squamous cell carcinoma
    Talita Antunes Guimarães, Lucyana Conceição Farias, Eliane Sobrinho Santos, Carlos Alberto de Carvalho Fraga, Lissur Azevedo Orsine, Leandro de Freitas Teles, John David Feltenberger, Sabrina Ferreira de Jesus, Marcela Gonçalves de Souza, Sérgio Henrique Sousa Santos et al. · 2016 · Oncotarget
  50. MicroRNA‐155 targets theSKIgene in human melanoma cell lines
    Lauretta Levati, Elena Pagani, Sveva Romani, Daniele Castiglia, Eugenia Piccinni, Claudia Covaciu, Patrizia Caporaso, Sergio Bondanza, Francesca Romana Antonetti, Enzo Bonmassar et al. · 2011 · Pigment Cell & Melanoma Research
  51. Conditional HIF-1 induction produces multistage neovascularization with stage-specific sensitivity to VEGFR inhibitors and myeloid cell independence
    Sunday S. Oladipupo, Song Hu, Andrea C. Santeford, Junjie Yao, Joanna R. Kovalski, Ralph V. Shohet, Konstantin Maslov, Lihong V. Wang, Jeffrey M. Arbeit · 2011 · Blood
  52. Contribution of the Type II Chaperonin, TRiC/CCT, to Oncogenesis
    Soung‐Hun Roh, Moses M. Kasembeli, Deenadayalan Bakthavatsalam, Wah Chiu, David John Tweardy · 2015 · International Journal of Molecular Sciences
  53. Heme oxygenase 1 (HO-1) challenges the angiogenic switch in prostate cancer
    Mercedes Ferrando, Geraldine Gueron, Belén Elguero, Jimena Giudice, Angeles Salles, Federico Coluccio Leskow, Elizabeth Andrea Jares-Erijman, Lucas Luis Colombo, Roberto Pablo Meiss, Nora Maria Navone et al. · 2011 · Angiogenesis
  54. Adverse reactions to targeted and non-targeted chemotherapeutic drugs with emphasis on hypersensitivity responses and the invasive metastatic switch
    Brian A. Baldo, Nghia H. Pham · 2013 · Cancer and Metastasis Reviews
  55. Follow the ATP: Tumor Energy Production: A Perspective
    Bryan T. Oronsky, Neil C. Oronsky, Gary R. Fanger, Christopher T. Parker, Scott Z. Caroen, Michelle Lybeck, Jan J. Scicinski · 2014 · Anti-Cancer Agents in Medicinal Chemistry
  56. The twisted survivin connection to angiogenesis
    Cristobal T. Sanhueza, Sergio Wehinger, J. Bennett, Manuel Valenzuela, Gareth I. Owen, Andrew F. G. Quest · 2015 · Molecular Cancer
  57. A Group of Novel HIF‐1α Inhibitors, Glyceollins, Blocks HIF‐1α Synthesis and Decreases Its Stability via Inhibition of the PI3K/AKT/mTOR Pathway and Hsp90 Binding
    Lee, Sun‐Hee, Jee, Jun‐Goo, Bae, Jong‐Sup, Liu, Kwang‐Hyoen, Lee, You Mie · 2015 · Journal of Cellular Physiology
  58. Magnolol suppresses hypoxia-induced angiogenesis via inhibition of HIF-1α/VEGF signaling pathway in human bladder cancer cells
    Meng‐Chuan Chen, Chi-Feng Lee, Wen‐Hsin Huang, Tz‐Chong Chou · 2013 · Biochemical Pharmacology
  59. The Ape‐1/Ref‐1 redox antagonist E3330 inhibits the growth of tumor endothelium and endothelial progenitor cells: Therapeutic implications in tumor angiogenesis
    Gang-Ming Zou, Collins A. Karikari, Yasuaki Kabe, Hiroshi Handa, Robert A. Anders, Anirban Maitra · 2008 · Journal of Cellular Physiology
  60. RNA‐binding proteins implicated in the hypoxic response
    Kiyoshi Masuda, Kotb Abdelmohsen, Myriam Gorospe · 2009 · Journal of Cellular and Molecular Medicine
  61. Mice with Inactivation of Aryl Hydrocarbon Receptor-Interacting Protein (Aip) Display Complete Penetrance of Pituitary Adenomas with Aberrant ARNT Expression
    Anniina Raitila, Heli J. Lehtonen, Johanna T. Arola, Elina Heliövaara, Manuel Ahlsten, Marianthi Georgitsi, Anu Jalanko, Anders E. Paetau, Lauri A. Aaltonen, Auli Karhu · 2010 · American Journal Of Pathology
  62. RETRACTED ARTICLE: hERG1 channels modulate integrin signaling to trigger angiogenesis and tumor progression in colorectal cancer
    Olivia Crociani, Francesca Zanieri, Serena Pillozzi, Elena Lastraioli, Matteo Stefanini, Antonella Fiore, Angelo Fortunato, Massimo D’Amico, Marika Masselli, Emanuele De Lorenzo et al. · 2013 · Scientific Reports · Retracted
  63. CXCR7 is up-regulated in human and murine hepatocellular carcinoma and is specifically expressed by endothelial cells
    Justin Monnier, Mathieu Boissan, Annie L’Helgoualc’h, Marie‐Lise Lacombe, Bruno Turlin, Jessica Zucman‐Rossi, Nathalie Théret, Claire Piquet‐Pellorce, Michel Samson · 2011 · European Journal of Cancer
  64. Hypoxia inducible factor 2 alpha inhibits hepatocellular carcinoma growth through the transcription factor dimerization partner 3/ E2F transcription factor 1–dependent apoptotic pathway
    Hai-Xiang Sun, Yang Xu, Xin‐Rong Yang, Weimin Wang, Haibo Bai, Ruo-Yu Shi, Suresh K. Nayar, Ranjan Prasad Devbhandari, Yi-zhou He, Qin-Feng Zhu et al. · 2012 · Hepatology
  65. CTGF is a therapeutic target for metastatic melanoma
    Elizabeth C. Finger, C-F Cheng, Thomas Robert Williams, Erinn B. Rankin, Barbara Bedogni, Lisa May Ling Tachiki, Suzanne M. Spong, Amato J. Giaccia, Marianne Broome Powell · 2013 · Oncogene
  66. Impact of Heat-Shock Protein 90 on Cancer Metastasis
    Shinji Tsutsumi, Kristin E. Beebe, Len Neckers · 2009 · Future Oncology
  67. Activation of Peroxisome Proliferator-activated Receptor α (PPARα) Suppresses Hypoxia-inducible Factor-1α (HIF-1α) Signaling in Cancer Cells
    Jundong Zhou, Shuyu Zhang, Jing Xue, Jori E. Avery, Jinchang Wu, Stuart E. Lind, Wei‐Qun Ding · 2012 · Journal of Biological Chemistry
  68. Coexpression of hypoxia-inducible factor-1α and glucose transporter-1 is associated with poor prognosis in oral squamous cell carcinoma patients
    Alexander W. Eckert, M.H.W. Lautner, Andreas Schütze, Helge W. Taubert, Johannes Schubert, Udo Bilkenroth · 2011 · Histopathology
  69. HIF prolyl hydroxylase inhibitors for anemia
    Eugene Muchnik, Joshua Kaplan · 2011 · Expert Opinion on Investigational Drugs
  70. The role of mucosal barriers in human gut health
    Kangseok Seo, Jeong-Mi Seo, Jiyoun Yeun, Haebin Choi, Young‐In Kim, Sun-Young Chang · 2021 · Archives of Pharmacal Research
  71. PHD3 regulates differentiation, tumour growth and angiogenesis in pancreatic cancer
    Yun Yan Su, Martin Loos, Nathalia A. Giese, Oscar Joe Hines, Isabel Diebold, Agnes Görlach, Eric Metzen, Silvia Pastoreková, Helmut Frieß, Peter Büchler · 2010 · British Journal of Cancer
  72. Correlation of biological aggressiveness assessed by 11C-methionine PET and hypoxic burden assessed by 18F-fluoromisonidazole PET in newly diagnosed glioblastoma
    Nobuyuki Kawai, Yukito Maeda, Nobuyuki Kudomi, Keisuke Miyake, Masaki Okada, Yuka Yamamoto, Yoshihiro Nishiyama, Takashi Tamiya · 2010 · European Journal of Nuclear Medicine and Molecular Imaging
  73. Hypoxia Modulates EWS-FLI1 Transcriptional Signature and Enhances the Malignant Properties of Ewing's Sarcoma Cells In vitro
    Dave N.T. Aryee, Stephan Niedan, Maximilian O. Kauer, Raphaela Schwentner, Idriss M. Bennani-Baı̈ti, Jozef Ban, Karin Muehlbacher, Michael Kreppel, Robert L. Walker, Paul S. Meltzer et al. · 2010 · Cancer Research
  74. Hypoxia-Induced Phenotypes that Mediate Tumor Heterogeneity
    Jin Qian, Erinn B. Rankin · 2019 · Advances in experimental medicine and biology
  75. Advances in the targeting of HIF-1α and future therapeutic strategies for glioblastoma multiforme
    Gang Wang, Junjie Wang, Xingli Fu, Rui Guang, Shing-shun Tony To · 2016 · Oncology Reports
  76. A redox-activated theranostic nanoagent: toward multi-mode imaging guided chemo-photothermal therapy
    Tingting Zhang, Cong-Hui Xu, Wei Zhao, Yu Gu, Xiang‐Ling Li, Jing‐Juan Xu, Hong‐Yuan Chen · 2018 · Chemical Science
  77. BODIPY-based probes for hypoxic environments
    Lizhi Gai, Yanfei Liu, Zhikuan Zhou, Hua Lü, Zijian Guo · 2023 · Coordination Chemistry Reviews
  78. Hypoxia upregulates ovarian cancer invasiveness via the binding of HIF‐1α to a hypoxia‐induced, methylation‐free hypoxia response element of S100A4 gene
    Akiko Horiuchi, Takuma Hayashi, Norihiko Kikuchi, Akiko Hayashi, Chiho Fuseya, Tanri Shiozawa, Ikuo Konishi · 2012 · International Journal of Cancer
  79. Redox Circuitries Driving Src Regulation
    Elisa Giannoni, Paola Chiarugi · 2013 · Antioxidants and Redox Signaling
  80. Recent Progress in the Design of Hypoxia‐Specific Nano Drug Delivery Systems for Cancer Therapy
    Abhishek Sahu, Won Il Choi, Giyoong Tae · 2018 · Advanced Therapeutics
  81. The Expression of AIP-Related Molecules in Elucidation of Cellular Pathways in Pituitary Adenomas
    Elina Heliövaara, Anniina Raitila, Virpi Launonen, Anders E. Paetau, Johanna T. Arola, Heli J. Lehtonen, Timo Sane, Robert John Weil, Outi Kuismin, Pasi I. Salmela et al. · 2009 · American Journal Of Pathology
  82. IGF binding protein‐6 expression in vascular endothelial cells is induced by hypoxia and plays a negative role in tumor angiogenesis
    Zhang, Chunyang, Lu, Ling, Li, Yun, Wang, Xianlei, Zhou, Jianfeng, Liu, Yunzhang, Fu, Ping, Gallicchio, Marisa A., Bach, Leon A., Duan, Cunming · 2012 · International Journal of Cancer
  83. Hypoxia-inducible factor in cancer: from pathway regulation to therapeutic opportunity
    Ortmann, Brian M · 2024 · BMJ Oncology
  84. Potent and sustained inhibition of HIF-1α and downstream genes by a polyethyleneglycol-SN38 conjugate, EZN-2208, results in anti-angiogenic effects
    Sapra, Puja, Kraft, Patricia, Pastorino, Fabio, Ribatti, Domenico, Dumble, Melissa, Mehlig, Mary, Wang, Maoliang, Ponzoni, Mirco, Greenberger, Lee M., Horak, Ivan D. · 2011 · Angiogenesis
  85. ZO Proteins and Redox-Dependent Processes
    Lorenza González‐Mariscal, Miguel Quirós, Mónica Díaz-Coránguez · 2011 · Antioxidants and Redox Signaling
  86. Delayed initiation of radiotherapy for glioblastoma: how important is it to push to the front (or the back) of the line?
    Yaacov Richard Lawrence, Deborah T. Blumenthal, Diana Matceyevsky, Andrew A. Kanner, Felix Bokstein, Benjamin William Corn · 2011 · Journal of Neuro-Oncology
  87. Clinicopathologic Significance of HIF‐1 α , CXCR4, and VEGF Expression in Colon Cancer
    Yugang Wu, Min Jin, Huanbai Xu, Zhang Shimin, Songbing He, Liang Wang, Yanyun Zhang · 2010 · Journal of Immunology Research
  88. Correlation of expression of hypoxia-related proteins with prognosis in oral squamous cell carcinoma patients
    Alexander W. Eckert, Matthias Kappler, Johannes Schubert, Helge W. Taubert · 2012 · Oral and Maxillofacial Surgery
  89. Hypoxia Inducible Factor 1α and Hypoxia Inducible Factor 2α Play Distinct and Functionally Overlapping Roles in Oral Squamous Cell Carcinoma
    Guiquan Zhu, Ya‐ling Tang, Ling Li, Min Hua Zheng, Jian Dong Jiang, Xiaoyu Li, Si-xiu Chen, Xin‐hua Liang · 2010 · Clinical Cancer Research
  90. Cancer as a Proinflammatory Environment: Metastasis and Cachexia
    Nelson Inácio Pinto Neto, June Carnier, Lila Missae Oyama, José Pinhata Otoch, Paulo Sérgio Martins de Alcântara, Flávio Tokeshi, Cláudia Maria Oller do Nascimento · 2015 · Mediators of Inflammation
  91. Nanoparticle‐Stabilized Oxygen Microcapsules Prepared by Interfacial Polymerization for Enhanced Oxygen Delivery
    Baiheng Wu, Zhu Sun, Jiangchao Wu, Jian Ruan, Peng Zhao, Kai Liu, Chun‐Xia Zhao, Jianpeng Sheng, Tingbo Liang, Dong Chen · 2021 · Angewandte Chemie International Edition
  92. Dual Hypoxia-Targeting RNAi Nanomedicine for Precision Cancer Therapy
    Yujing Li, Jianxun Ding, Xiaoding Xu, Run Shi, Phei Er Saw, Junqing Wang, Shirley Chung, Wenliang Li, Bader Mubarak Aljaeid, Robert J. Lee et al. · 2020 · Nano Letters
  93. Downregulating hypoxia‐inducible factor‐2α improves the efficacy of doxorubicin in the treatment of hepatocellular carcinoma
    Changjun He, Xuepu Sun, Haiquan Qiao, Xian Jiang, Dongdong Wang, Xiangguo Jin, Xuesong Dong, Jizhou Wang, Hongchi Jiang, Xueying Sun · 2011 · Cancer Science
  94. Hsp90 as a Gatekeeper of Tumor Angiogenesis: Clinical Promise and Potential Pitfalls
    Jessica E. S. Bohonowych, Udhayakumar Gopal, Jennifer S. Isaacs · 2010 · Journal of Oncology
  95. Andrographolide down-regulates hypoxia-inducible factor-1α in human non-small cell lung cancer A549 cells
    Hui‐Hsuan Lin, Chia-Wen Tsai, Fen‐Pi Chou, Chau‐Jong Wang, Shu‐Wen Hsuan, Cheng-Kun Wang, Jing‐Hsien Chen · 2010 · Toxicology and Applied Pharmacology
  96. Two Distinct Roles for EGL-9 in the Regulation of HIF-1-Mediated Gene Expression in Caenorhabditis elegans
    Zhiyong Shao, Yi Zhang, Jo Anne Powell‐Coffman · 2009 · Genetics
  97. The inhibition of hypoxia‐induced angiogenesis and metastasis by cinnamaldehyde is mediated by decreasing HIF‐1α protein synthesis via PI3K/Akt pathway
    Kartick Patra, Samarjit Jana, Arnab Sarkar, Deba Prasad Mandal, Shamee Bhattacharjee · 2019 · BioFactors
  98. Hypoxia-inducible factor-prolyl hydroxylase inhibitors for renal anemia in chronic kidney disease: Advantages and disadvantages
    Akira Mima · 2021 · European Journal of Pharmacology
  99. HILPDA promotes NASH-driven HCC development by restraining intracellular fatty acid flux in hypoxia
    Davide Povero, Yongbin Chen, Scott M. Johnson, Cailin E. McMahon, Meixia Pan, Hanmei Bao, Xuan-Mai T. Petterson, Emily Blake, Kimberly P. Lauer, Daniel R. O’Brien et al. · 2023 · Journal of Hepatology
  100. Hypoxia-Mediated Metastasis
    Joan Chang, Janine Terra Erler · 2013 · Advances in experimental medicine and biology