The role of hypoxia-inducible factors in tumorigenesis
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- Osteopontin Upregulates the Expression of Glucose Transporters in Osteosarcoma CellsI‐Shan Hsieh, Rong‐Sen Yang, Wen Fu · 2014 · PLoS ONE
- Physiological Targeting to Improve Anticancer Drug SelectivityTrevor W. Hambley · 2008 · Australian Journal of Chemistry
- Hypoxia-inducible factor: roles in development, physiology, and diseaseChandel, N S, Simon, M C · 2008 · Cell Death & Differentiation
- 2ME2 inhibits the activated hypoxia-inducible pathways by cabozantinib and enhances its efficacy against medullary thyroid carcinomaHan Lin, Xian Li Jiang, Huaqiang Zhu, Wenjing Jiang, Xuesong Dong, Haiquan Qiao, Xueying Sun, Hongchi Jiang · 2015 · Tumor Biology
- On the relationship between VDR, RORα and RORγ receptors expression and HIF1‐α levels in human melanomasAnna A. Brożyna, Wojciech Jóźwicki, Anton M. Jetten, Andrzej T. Slominski · 2019 · Experimental Dermatology
- Tumor suppressor WWOX moderates the mitochondrial respiratory complexAmanda Choo, Louise V. O’Keefe, Cheng Shoou Lee, Stephen L. Gregory, Zeeshan Shaukat, Alexander D. Colella, Kristie Lee, Donna Denton, Robert I. Richards · 2015 · Genes Chromosomes and Cancer
- Hypoxia-inducible factors in mantle cell lymphoma: implication for an activated mTORC1→HIF-1α pathwayPinelopi Argyriou, Sotirios G. Papageorgiou, Varvara Panteleon, Amanda K. Psyrri, Vassiliki Bakou, Vasiliki Pappa, Aris Spathis, Panagiota Economopoulou, E. S. Papageorgiou, Theofanis Economopoulos et al. · 2010 · Annals of Hematology
- Prognostic Role of Hypoxic Inducible Factor Expression in Non-small Cell Lung Cancer: A Meta-analysisCong Li, Hua-Jun Lu, Feifei Na, Lei Deng, Jianxin Xue, Jingwen Wang, Yuqing Wang, Qiaoling Li, You Lü · 2013 · Asian Pacific Journal of Cancer Prevention
- Distribution of Hypoxia-Inducible Factor-1α and Glucose Transporter-1 in Human Tongue CancersMarcelo Gadelha Vasconcelos, Rodrigo Gadelha VASCONCELOS, Denise Hélen Imaculada Pereira de Oliveira, Edilmar de Moura Santos, Leão Pereira Pinto, Éricka Janine Dantas da Silveira, Lélia María Guedes Queiroz · 2015 · Journal of Oral and Maxillofacial Surgery
- Polyphyllin D Exerts Potent Anti-tumour Effects on Lewis Cancer Cells under Hypoxic ConditionsD-D Ma, H-X Lu, L-S Xu, Wei Lie Xiao · 2009 · Journal of International Medical Research
- Association between FBP1 and hypoxia-related gene expression in clear cell renal cell carcinomaXianghui Ning, Li Teng, Yanqing Gong, Qun He, QI SHEN, Shuanghe Peng, Jiangyi Wang, JIN-CHAO CHEN, Yinglu Guo, Kan Gong · 2016 · Oncology Letters
- Inhibition of histone/lysine acetyltransferase activity kills CoCl2-treated and hypoxia-exposed gastric cancer cells and reduces their invasivenessSuvasmita Rath, Lopamudra Das, Shrikant Babanrao Kokate, Nilabh Ghosh, Pragyesh Dixit, Niranjan Rout, Shivaram Prasad Singh, Subhasis Chattopadhyay, Hassan Ashktorab, Duane T. Smoot et al. · 2016 · The International Journal of Biochemistry & Cell Biology
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- The anti-ovarian cancer activity by WYE-132, a mTORC1/2 dual inhibitorDan Zhang, Hexia Xia, Wei Zhang, Bo Fang · 2015 · Tumor Biology
- Prolyl Hydroxylase Inhibition Enhances Liver Regeneration Without Induction of Tumor GrowthJonathan M. Harnoss, Lisa Katharina Platzer, Jürgen Burhenne, Praveen Radhakrishnan, Jun Cai, Moritz J. Strowitzki, Johanna Weiß, Alina S. Ritter, Martin Mollenhauer, Thomas Schmidt et al. · 2016 · Annals of Surgery
- Association Between Hypoxia-Inducible Factor-2α (HIF-2α) Expression and Colorectal Cancer and Its Prognostic Role: a Systematic AnalysisSusu Han, Tao Huang, Wen Li, Shanshan Liu, Wei Yang, Qi Shi, Hongjia Li, Jianlin Ren, Fenggang Hou · 2018 · Cellular Physiology and Biochemistry
- The Role of Tumor Microenvironment in Regulating the Plasticity of Osteosarcoma CellsBoren Tian, Xiaoyun Du, Shiyu Zheng, Yan Zhang · 2022 · International Journal of Molecular Sciences
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- Biological characteristics and clinical treatment of pulmonary sarcomatoid carcinoma: a narrative reviewYuxuan Wei, Lei Wang, Jin Zheng, Qingzhu Jia, Luka Brčić, Tomohiro Akaba, Qian Chu · 2024 · Translational Lung Cancer Research
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- The Effect of GLUT1 and HIF-1α Expressions on Glucose Uptake and Patient Survival in Non-Small-Cell Lung CarcinomaJosipa Kokeza, Ante Strikić, Marin Ogorevc, Nela Kelam, Martina Vukoja, Ivo Dilber, Sandra Zekić Tomaš · 2023 · International Journal of Molecular Sciences
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- Microarray analyses of hypoxia‐regulated genes in an aryl hydrocarbon receptor nuclear translocator (Arnt)‐dependent mannerSu‐Mi Choi, Hookeun Oh, Hyunsung Park · 2008 · FEBS Journal
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- Bifurcated BACH2 control coordinates mantle cell lymphoma survival and dispersal during hypoxiaHan Zhang, Zheng Chen, Roberto N. Miranda, Leonard Jeffrey Medeiros, Nami McCarty · 2017 · Blood
- Paradoxical Regulation of Hypoxia Inducible Factor-1α (HIF-1α) by Histone Deacetylase Inhibitor in Diffuse Large B-Cell LymphomaSavita Bhalla, Andrew M. Evens, Sheila Prachand, Paul T. Schumacker, Leo I. Gordon · 2013 · PLoS ONE
- The relationship between the preoperative plasma level of HIF-1α and clinic pathological features, prognosis in non-small cell lung cancerJiabei He, Ying Hu, Ming‐Ming Hu, Siyi Zhang, Baolan Li · 2016 · Scientific Reports
- Ischemia Is Related to Tumour Genetics in Uveal MelanomaNiels J. Brouwer, Annemijn P. A. Wierenga, Gülçin Gezgin, Marina Marinkovic, Gregorius P. M. Luyten, Wilma G. M. Kroes, Mieke Versluis, Pieter A. van der Velden, Robert M. Verdijk, Martine Johanna Jager · 2019 · Cancers
- Metabolic Potential of Cancer Cells in Context of the Metastatic CascadeMohaned Benzarti, Catherine Delbrouck, Laura Neises, Nicole Kiweler, Johannes Meiser · 2020 · Cells
- Combinatorial Control of Transgene Expression by Hypoxia-Responsive Promoter and MicroRNA Regulation for Neural Stem Cell-Based Cancer TherapyYumei Luo, Detu Zhu · 2014 · BioMed Research International
- Integration and Visualization of Regulatory Elements and Variations of the EPAS1 Gene in HumanAleša Kristan, Nataša Debeljak, Tanja Kunej · 2021 · Genes
- Programming DNA Nanoassembly for Enhanced Photodynamic TherapyMin Pan, Qunying Jiang, Junlin Sun, Zhen Xu, Yizhuo Zhou, Li Zhang, Xiaoqing Liu · 2019 · Angewandte Chemie
- Complex role of HIF in cancer: the known, the unknown, and the unexpectedEric L. Huang, Patricia D.B. Tiburcio, Hyunsung Choi · 2014 · Hypoxia
- Hypoxia-inducible factor-1α regulates the expression of L-type voltage-dependent Ca2+ channels in PC12 cells under hypoxiaRan Li, Yong Wang, Zhaofei Yang, Yun‐Ling He, Tong Zhao, Ming Fan, Xuan Wang, L C Zhu, Xiaomin Wang · 2015 · Cell Stress and Chaperones
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- Mutational analysis of hypoxia‐related genes HIF1α and CUL2 in common human cancersSang Wook Park, Nak Gyun Chung, Soo Young Hur, Ho Shik Kim, Nam Jin Yoo, Sug Hyung Lee · 2009 · Apmis
- Hypoxia-induced decoy receptor 2 gene expression is regulated via a hypoxia-inducible factor 1α-mediated mechanismGuo-Ting Pei, Chi-Wei Wu, Wan‐Wan Lin · 2009 · Biochemical and Biophysical Research Communications
- Quantification of hypoxia-related gene expression as a potential approach for clinical outcome prediction in breast cancerAbderrahim El Guerrab, Anne Cayre, Fabrice Kwiatkowski, Maud Privat, Jean-Marc Rossignol, Fabrice Rossignol, Frederique Madeleine Penault-Llorca, Yves‐Jean Bignon · 2017 · PLoS ONE
- TRIB3 Promotes Lung Adenocarcinoma Progression via an Enhanced Warburg EffectYutong Xing, Peng Luo, Rui Hu, Duanduan Wang, Gang Zhou, Jie Jiang · 2020 · Cancer Management and Research
- GLUT3/SLC2A3 Is an Endogenous Marker of Hypoxia in Prostate Cancer Cell Lines and Patient-Derived Xenograft TumorsJohn M. Ryniawec, Matthew R. Coope, Emily Loertscher, Vignesh Bageerathan, Diogo de Oliveira Pessôa, Noel A. Warfel, Anne E. Cress, Megha Padi, Gregory C. Rogers · 2022 · Diagnostics
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- Forces at play: exploring factors affecting the cancer metastasisFarooq Riaz, Jing Zhang, Fan Pan · 2024 · Frontiers in Immunology
- Targeting acute hypoxic cancer cells by doxorubicin-immunoliposomes directed by monoclonal antibodies specific to RON receptor tyrosine kinaseSunny Guin, Qi Ma, Snehal Padhye, Yong-Qing Zhou, Hangping Yao, Ming‐Hai Wang · 2010 · Cancer Chemotherapy and Pharmacology
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- Role, Targets and Regulation of (de)nitrosylation in MalignancySalvatore Rizza, Giuseppe Filomeni · 2018 · Frontiers in Oncology
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- Boosting Nanomedicine Efficacy with Hyperbaric Oxygen TherapyXiaoxian Wang, Si Li, Xin Liu, Xian Guo Wu, Ningbing Ye, Xiangliang Yang, Zifu Li · 2021 · Advances in experimental medicine and biology
- Betacellulin inhibits osteogenic differentiation and stimulates proliferation through HIF-1αDamian C. Genetos, Rameshwar R. Rao, Martin A. Vidal · 2010 · Cell and Tissue Research
- HIF1-positive and HIF1-negative glioblastoma cells compete in vitro but cooperate in tumor growth in vivoSonia Levi · 2010 · International Journal of Oncology
- Expression of nerve growth factor and hypoxia inducible factor-1α and its correlation with angiogenesis in non-small cell lung cancerQingli Lu, Jian Liu, Xiaoli Zhu, Wenjia Xu · 2014 · Journal of Huazhong University of Science and Technology [Medical Sciences]
- FMISO-Based Adaptive Radiotherapy in Head and Neck CancerMartin Doležel, M Slavík, Tomáš Blažek, Tomáš Kazda, Pavel Koranda, Lucia Veverková, Petr Burkoň, Jakub Cvek · 2022 · Journal of Personalized Medicine
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- Prognostic Value of Molecular Markers and Implication for Molecular Targeted Therapies in Nasopharyngeal Carcinoma: An Update in an Era of New Targeted Molecules DevelopmentMu-Tai Liu, Mu-Kuan Chen, Chia-Chun Huang, Chao‐Yuan Huang · 2015 · World Journal of Oncology
- Hypoxia-related gene expression profile in childhood acute lymphoblastic leukemia: prognostic implicationsVanessa S. Silveira, Bruno Marcelo Rocha Freire, Kleiton Silva Borges, Augusto Faria Andrade, Gustavo Alencastro Veiga Cruzeiro, João Paulo J. Sabino, Mogens Lesner Glass, José Andrés Yunes, Sílvia Regina Brandalise, Luíz Gonzaga Tone et al. · 2013 · Leukemia & lymphoma/Leukemia and lymphoma
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- Perioperative Treatment with a Prolyl Hydroxylase Inhibitor Reduces Necrosis in a Rat Ischemic Skin Flap ModelAmanda R. Sergesketter, Roger W. Cason, Mohamed M. Ibrahim, Whitney O. Lane, David T. Lubkin, Scott Thomas Hollenbeck, David A. Brown · 2019 · Plastic & Reconstructive Surgery
- Caveolin-1-Mediated Tumor Suppression Is Linked to Reduced HIF1α S-Nitrosylation and Transcriptional Activity in HypoxiaCarlos Sanhueza, Jimena Castillo Bennett, Manuel Valenzuela, Pamela Contreras, Lorena Lobos‐González, America V. Campos, Sergio Wehinger, Álvaro Lladser, Rolf W. Kiessling, Lisette Leyton et al. · 2020 · Cancers