Development of a single-frequency bioimpedance prediction equation for fat-free mass in an adult Indigenous Australian population
Abstract
Background/objectives To describe the development of a single-frequency bioimpedance prediction equation for fat-free mass (FFM) suitable for adult Aboriginal and Torres Strait Islander peoples with and without diabetes or indicators of chronic kidney disease (CKD).Subjects/methods FFM was measured by whole-body dual-energy X-ray absorptiometry in 147 adult Indigenous Australians. Height, weight, body circumference and resistance were also measured. Adults with and without diabetes and indicators of CKD were examined. A random split sample with internal cross-validation approach was used to predict and subsequently validate FFM using resistance, height, weight, age and gender against measured FFM.Results Among 147 adults with a median body mass index of 31 kg/m(2), the final model of FFM was FFM (kg)=0.432 (height, cm(2)/resistance, ohm)-0.086 (age, years)+0.269 (weight, kg)-6.422 (if female)+16.429. Adjusted R(2) was 0.94 and the root mean square error was 3.33 kg. The concordance was high (rc=0.97) between measured and predicted FFM across a wide range of FFM (31-85 kg).Conclusions In the context of the high burden of diabetes and CKD among adult Indigenous Australians, this new equation for FFM was both accurate and precise and based on easily acquired variables (height, weight, age, gender and resistance) among a heterogeneous adult cohort.
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Concerns with applicability were unclear in 12 studies.
“Concerns with applicability were high in 19 studies [37, 42–59] and unclear [41, 50, 60–69] in 12 studies due to the restricted sample size.”
From High-standard predictive equations for estimating body composition using bioelectrical impedance analysis: a systematic review (2024) · cites this paper as [66]
All adult equations were developed at a single frequency of 50 kHz, with the exception of four equations developed with multifrequency devices.
“All these equations were developed at a single frequency of 50 kHz, with the exception of four equations [66, 81] developed with a multifrequency devices that used bioelectrical parameters measured only at 50 kHz [66], as well as mixing frequencies sampled at 50 and 250 kHz [81].”
From High-standard predictive equations for estimating body composition using bioelectrical impedance analysis: a systematic review (2024) · cites this paper as [66]
Four adult equations were developed with multifrequency devices that used bioelectrical parameters measured only at 50 kHz.
“All these equations were developed at a single frequency of 50 kHz, with the exception of four equations [66, 81] developed with a multifrequency devices that used bioelectrical parameters measured only at 50 kHz [66], as well as mixing frequencies sampled at 50 and 250 kHz [81].”
From High-standard predictive equations for estimating body composition using bioelectrical impedance analysis: a systematic review (2024) · cites this paper as [66]
Regarding foot-to-hand technology for adults, five equations are suitable for estimating FFM in males.
“Regarding foot-to-hand technology, five equations are suitable for estimating FFM in males [47, 52, 66, 71, 78] and six in females [34, 47, 50, 52, 66, 71].”
From High-standard predictive equations for estimating body composition using bioelectrical impedance analysis: a systematic review (2024) · cites this paper as [66]
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- Authors
- Hughes, J. T., Maple-Brown, L. J., Piers, L. S., Meerkin, J., O'Dea, K., & Ward, L. C.
- Affiliations
- Charles Darwin University (AU)
- The University of Melbourne (AU)
- The University of Queensland (AU)
- Corresponding author
- Ward, L C
- Venue
- European Journal of Clinical Nutrition
- Published
- 2014-04-23
- Volume
- 69
- Issue
- 1
- Pages
- 28-33
- ISSN
- 0954-3007 (ISSN-L)
- 1476-5640
- OpenAlex
- W2083872786
- Cited by
- 12
- References
- 34
- Citations by year
- 2026: 1 · 2024: 2 · 2021: 2 · 2019: 1 · 2018: 2 · 2016: 1 · 2015: 3
- FWCI
- 0.89
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- European Journal of Clinical Nutrition (publishedVersion)
- PubMed (publishedVersion)
- Adelaide Research & Scholarship (AR&S) (University of Adelaide) (submittedVersion)
- Topics
- Health Sciences › Medicine › Physiology › Body Composition Measurement Techniques
- Health Sciences › Medicine › Physiology › Nutrition and Health in Aging
- Health Sciences › Health Professions › General Health Professions › Indigenous Health and Education
- Keywords
- fat-free mass, prediction equations, Indigenous Australians, Aboriginal and Torres Strait Islander peoples, diabetes mellitus, chronic kidney disease, body composition, body resistance
- MeSH terms
- Adult, Australia, Body Composition, Body Height, Body Weight, Diabetes Mellitus, Female, Glomerular Filtration Rate, Humans, Male, Middle Aged, Absorptiometry, Photon, Body Mass Index, Electric Impedance, Native Hawaiian or Other Pacific Islander, Renal Insufficiency, Chronic
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