The DOI matches its Crossref record; 31 of the 31 references it cites were found in a registry or an index.
Parvalbumin neurons and gamma rhythms enhance cortical circuit performance
Open accessAbstract
Synchronized oscillations and inhibitory interneurons have important and interconnected roles within cortical microcircuits. In particular, interneurons defined by the fast-spiking phenotype and expression of the calcium-binding protein parvalbumin have been suggested to be involved in gamma (30-80 Hz) oscillations, which are hypothesized to enhance information processing. However, because parvalbumin interneurons cannot be selectively controlled, definitive tests of their functional significance in gamma oscillations, and quantitative assessment of the impact of parvalbumin interneurons and gamma oscillations on cortical circuits, have been lacking despite potentially enormous significance (for example, abnormalities in parvalbumin interneurons may underlie altered gamma-frequency synchronization and cognition in schizophrenia and autism). Here we use a panel of optogenetic technologies in mice to selectively modulate multiple distinct circuit elements in neocortex, alone or in combination. We find that inhibiting parvalbumin interneurons suppresses gamma oscillations in vivo, whereas driving these interneurons (even by means of non-rhythmic principal cell activity) is sufficient to generate emergent gamma-frequency rhythmicity. Moreover, gamma-frequency modulation of excitatory input in turn was found to enhance signal transmission in neocortex by reducing circuit noise and amplifying circuit signals, including inputs to parvalbumin interneurons. As demonstrated here, optogenetics opens the door to a new kind of informational analysis of brain function, permitting quantitative delineation of the functional significance of individual elements in the emergent operation and function of intact neural circuitry.
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In the citing paper
“strong evidence supporting the view that PV-expressing basket cells have critical roles in the generation and maintenance of gamma, theta and ripple oscillations”
From GABAergic Interneurons in the Neocortex: From Cellular Properties to Circuits (2016) · cites this paper as Sohal et al., 2009
Experimental — accuracy not yet measuredThe source backs part of the claim, not all of it — or backs it for a different population, condition or comparison.
In the citing paper
“We used a sensory paradigm to induce a synchronous activated state in the prefrontal neuronal circuitry and, thus, elicit u oscillations with a nested g activity (Sohal et al., 2009)”
From Perineuronal Nets Regulate the Inhibitory Perisomatic Input onto Parvalbumin Interneurons and γ Activity in the Prefrontal Cortex (2020) · cites this paper as Sohal et al., 2009
Experimental — accuracy not yet measuredThe check wasn’t confident either way, so it gives no verdict — never disputed.
In the citing paper
“Fast-spiking properties consequently impose high metabolic demand and increased mitochondrial density, which renders PV cells, but not other interneurons such as calretinin and calbindin cells, particularly sensitive to oxidative stress (3).”
From Perineuronal nets protect fast-spiking interneurons against oxidative stress (2013) · cites this paper as [3]
Experimental — accuracy not yet measuredThe check wasn’t confident either way, so it gives no verdict — never disputed.
In the citing paper
“Furthermore, the antioxidant N-acetylcysteine prevents the GBRinduced PV-cell defect in Gclm KO mice (3).”
From Perineuronal nets protect fast-spiking interneurons against oxidative stress (2013) · cites this paper as [3]
Experimental — accuracy not yet measuredIn the citing paper
“Cortical PV cells contribute to synchronous oscillatory activity (Cardin et al., 2009; Sohal et al., 2009; Uhlhaas et al., 2009), particularly in the gamma range (∼30–100 Hz).”
From The Perineuronal ‘Safety’ Net? Perineuronal Net Abnormalities in Neurological Disorders (2018) · cites this paper as Sohal et al., 2009
In the citing paper
“Cortical gamma band oscillations have been attributed to GABAergic cell activity, in particular PV interneurons (Sohal et al., 2009).”
From The Perineuronal ‘Safety’ Net? Perineuronal Net Abnormalities in Neurological Disorders (2018) · cites this paper as Sohal et al., 2009
In the citing paper
“FS-PV interneurons are at the origin of gamma oscillation in the cortex and contribute to cognitive functions.29, 30”
From Cortical fast-spiking parvalbumin interneurons enwrapped in the perineuronal net express the metallopeptidases Adamts8, Adamts15 and Neprilysin (2015) · cites this paper as [30]
In the citing paper
“Two foundational optogenetic studies demonstrated that optogenetically driving inhibitory interneurons specifically enhances slow gamma frequency oscillations throughout cortex, reducing circuit noise while amplifying circuit signal [201, 202].”
From Apolipoprotein E4, inhibitory network dysfunction, and Alzheimer’s disease (2019) · cites this paper as [202]
In the citing paper
“there is evidence that gamma oscillations may facilitate cortical circuit performance and enhance information transmission by increasing signal-to-noise ratio within neocortical circuits (Sohal et al, 2009).”
From Neural Correlates of Three Promising Endophenotypes of Depression: Evidence from the EMBARC Study (2016) · cites this paper as Sohal et al, 2009
In the citing paper
“Stimulation of PV-INs leads to an increase in gamma oscillation patterns, while inhibition of PV-INs or downregulation of PV at cortical synapses reduces gamma oscillations [76][77][78].”
From Parvalbumin interneuron vulnerability and brain disorders (2021) · cites this paper as [77]
In the citing paper
“Inhibition of PV interneurons led to an immediate suppression of 30–80 Hz oscillations while 10–30 Hz oscillations increased in power.”
From Neuronal Dynamics and Neuropsychiatric Disorders: Toward a Translational Paradigm for Dysfunctional Large-Scale Networks (2012) · cites this paper as Sohal et al., 2009
In the citing paper
“Increasingly, evidence is emerging that decreased inhibition is a critical contributor to E/I imbalance in ASD40.”
From Regulation of autism-relevant behaviors by cerebellar-prefrontal cortical circuits (2020) · cites this paper as [40]
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Citations
Cites
Millisecond-timescale, genetically targeted optical control of neural activity
Boyden, E. S., Zhang, F., Bamberg, E., Nagel, G., & Deisseroth, K. A. (2005) · Nature Neuroscience · doi:10.1038/nn1525 · Cited by 5,015
Self-citationModulation of Oscillatory Neuronal Synchronization by Selective Visual Attention
Fries, P., Reynolds, J. H., Rorie, A. E., & Desimone, R. (2001) · Science · doi:10.1126/science.1055465 · Cited by 2,786
Cortical inhibitory neurons and schizophrenia
Lewis, D. A., Hashimoto, T., & Volk, D. W. (2005) · Nature Reviews Neuroscience · doi:10.1038/nrn1648 · Cited by 2,297
Perception's shadow: long-distance synchronization of human brain activity
Rodriguez, E., George, N., Lachaux, J.-P., Martinerie, J., Renault, B., & Varela, F. J. (1999) · Nature · doi:10.1038/17120 · Cited by 1,915
Transgenic strategies for combinatorial expression of fluorescent proteins in the nervous system
Livet, J., Weissman, T. A., Kang, H., Draft, R. W., Lu, J., Bennis, R. A., Sanes, J. R., & Lichtman, J. W. (2007) · Nature · doi:10.1038/nature06293 · Cited by 1,876
Multimodal fast optical interrogation of neural circuitry
Zhang, F., Wang, L., Brauner, M., Liewald, J. F., Kay, K., Watzke, N., Wood, P. G., Bamberg, E., Nagel, G., GOTTSCHALK, A. R., et al. (2007) · Nature · doi:10.1038/nature05744 · Cited by 1,766
Self-citationWhittington, M. A., Traub, R. D., & Jefferys, J. G. R. (1995) · Nature · doi:10.1038/373612a0 · Cited by 1,613
Cellular and network mechanisms of rhythmic recurrent activity in neocortex
Sanchez-Vives, M. V., & McCormick, D. A. (2000) · Nature Neuroscience · doi:10.1038/79848 · Cited by 1,539
Modulation of Neuronal Interactions Through Neuronal Synchronization
Womelsdorf, T., Schoffelen, J.-M., Oostenveld, R., Singer, W., Desimone, R., Engel, A. K., & Fries, P. (2007) · Science · doi:10.1126/science.1139597 · Cited by 1,367
Aravanis, A. M., Wang, L., Zhang, F., Meltzer, L. A., Mogri, M., Schneider, M. B., & Deisseroth, K. A. (2007) · Journal of Neural Engineering · doi:10.1088/1741-2560/4/3/s02 · Cited by 960
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Items 801–900 of 1,013
Lee, S.-H., Dudok, B., Parihar, V. K., Jung, K., Zöldi, M., Kang, Y., Maroso, M., Alexander, A., Nelson, G. A., Piomelli, D., et al. (2016) · Brain Structure and Function · doi:10.1007/s00429-016-1345-3 · Cited by 54
Lee, S., Lee, E., Kim, R., Kim, J., Lee, S., Park, H., Yang, E., Kim, H., & Kim, E. (2018) · Frontiers in Molecular Neuroscience · doi:10.3389/fnmol.2018.00209 · Cited by 54
Embracing Complexity in Defensive Networks
Headley, D. B., Kanta, V., Kyriazi, P., & Paré, D. (2019) · Neuron · doi:10.1016/j.neuron.2019.05.024 · Cited by 61
Camp, C. R., & Yuan, H. (2019) · European Journal of Paediatric Neurology · doi:10.1016/j.ejpn.2019.12.007 · Cited by 54
Rodriguez, S., Şahin, A., Schrank, B. R., Lawati, H. J. A., Costantino, I. M., Benz, E. G., Fard, D., Albers, A. D., Cao, L., Gomez, A. C., et al. (2021) · Science Translational Medicine · doi:10.1126/scitranslmed.aaz4699 · Cited by 58
On the neurobiology of hallucinations
Boksa, P. (2009) · Journal of Psychiatry and Neuroscience · doi:10.1139/jpn.0934 · Cited by 54
GABAergic System Dysfunction and Challenges in Schizophrenia Research
Jahangir, M., Zhou, J., Lang, B., & Wang, X. (2021) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2021.663854 · Cited by 55
Inhibition in the auditory cortex
Studer, F., & Barkat, T. R. (2021) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2021.11.021 · Cited by 56
Becoming a mother — circuit plasticity underlying maternal behavior
Elyada, Y. M., & Mizrahi, A. (2015) · Current Opinion in Neurobiology · doi:10.1016/j.conb.2015.06.007 · Cited by 55
Gaucher, Q., Huetz, C., Gourévitch, B., & Edeline, J. (2013) · Journal of Neuroscience · doi:10.1523/jneurosci.0079-13.2013 · Cited by 54
Tanaka, D. H., Toriumi, K., Kubo, K., Nabeshima, T., & Nakajima, K. (2011) · Journal of Neuroscience · doi:10.1523/jneurosci.2786-11.2011 · Cited by 56
High-frequency neural oscillations and visual processing deficits in schizophrenia
Tan, H. M., Lana, L., & Uhlhaas, P. J. (2013) · Frontiers in Psychology · doi:10.3389/fpsyg.2013.00621 · Cited by 53
Snakes elicit earlier, and monkey faces, later, gamma oscillations in macaque pulvinar neurons
Le, Q. V., Isbell, L. A., Matsumoto, J., Le, Q. V., Nishimaru, H., Hori, E., Maior, R. S., Tomaz, C. A. B., Ono, T., & Nishijo, H. (2016) · Scientific Reports · doi:10.1038/srep20595 · Cited by 52
Neural synchronization in Alzheimer's disease
Aron, L., & Yankner, B. A. (2016) · Nature · doi:10.1038/540207a · Cited by 52
Mapping pathologic circuitry in schizophrenia
Glausier, J. R., & Lewis, D. A. (2018) · Handbook of clinical neurology · doi:10.1016/b978-0-444-63639-3.00025-6 · Cited by 53
Activation of Meiotic Genes Mediates Ploidy Reduction during Cryptococcal Infection
Zhao, Y., Wang, Y., Upadhyay, S., Xue, C., & Lin, X. (2020) · Current Biology · doi:10.1016/j.cub.2020.01.081 · Cited by 52
Joffe, M. E., Winder, D. G., & Conn, P. J. (2020) · Neuropharmacology · doi:10.1016/j.neuropharm.2020.108126 · Cited by 53
Sugiyama, S., Ohi, K., Kuramitsu, A., Takai, K., Muto, Y., Taniguchi, T., Kinukawa, T. A., Takeuchi, N., Motomura, E., Nishihara, M., et al. (2021) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2021.644541 · Cited by 55
Global and Parallel Cortical Processing Based on Auditory Gamma Oscillatory Responses in Humans
Tada, M., Kirihara, K., Ishishita, Y., Takasago, M., Kunii, N., Uka, T., Shimada, S., Ibayashi, K., Kawai, K., Saito, N., et al. (2021) · Cerebral Cortex · doi:10.1093/cercor/bhab103 · Cited by 52
Amegandjin, C. A., Choudhury, M., Jadhav, V., Carriço, J. N., Quintal, A., Berryer, M. H., Snapyan, M., Chattopadhyaya, B., Saghatelyan, A., & Cristo, G. D. (2021) · Nature Communications · doi:10.1038/s41467-021-23939-7 · Cited by 53
The elusive engram: what can infantile amnesia tell us about memory?
Callaghan, B. L., Li, S., & Richardson, R. (2014) · Trends in Neurosciences · doi:10.1016/j.tins.2013.10.007 · Cited by 51
Koh, M. T., Shao, Y., Sherwood, A., & Smith, D. R. (2016) · Schizophrenia Research · doi:10.1016/j.schres.2016.01.023 · Cited by 51
Fincham, G. W., Kartar, A. A., Uthaug, M. V., Anderson, B., Hall, L., Nagai, Y., Critchley, H., & Colasanti, A. (2023) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2023.105453 · Cited by 52
Altered Markers of Cortical γ-Aminobutyric Acid Neuronal Activity in Schizophrenia
Kimoto, S., Zaki, M. M., Bazmi, H. H., & Lewis, D. A. (2015) · JAMA Psychiatry · doi:10.1001/jamapsychiatry.2015.0533 · Cited by 53
Hay, Y. A., Lambolez, B., & Tricoire, L. (2015) · Cerebral Cortex · doi:10.1093/cercor/bhv085 · Cited by 51
Witt, A., Palmigiano, A., Neef, A., Hady, A. E., Wolf, F., & Battaglia, D. A. (2013) · Frontiers in Neural Circuits · doi:10.3389/fncir.2013.00049 · Cited by 52
An optogenetic approach in epilepsy
Kokaia, M., Andersson, M., & Ledri, M. (2012) · Neuropharmacology · doi:10.1016/j.neuropharm.2012.05.049 · Cited by 53
Bitzenhofer, S. H., Sieben, K., Siebert, K. D., Spehr, M., & Hanganu‐Opatz, I. L. (2015) · Cell Reports · doi:10.1016/j.celrep.2015.03.031 · Cited by 52
The Energy Demand of Fast Neuronal Network Oscillations: Insights from Brain Slice Preparations
Kann, O. (2012) · Frontiers in Pharmacology · doi:10.3389/fphar.2011.00090 · Cited by 52
Cortical Opioid Markers in Schizophrenia and across Postnatal Development
Volk, D. W., Radchenkova, P., Er, W., Sengupta, E. J., & Lewis, D. A. (2011) · Cerebral Cortex · doi:10.1093/cercor/bhr202 · Cited by 51
Demars, M. P., & Morishita, H. (2014) · Molecular Brain · doi:10.1186/s13041-014-0075-9 · Cited by 54
Sherwood, C. C., Raghanti, M. A., Stimpson, C. D., Spocter, M. A., Uddin, M., Boddy, A. M., Wildman, D. E., Bonar, C. J., Lewandowski, A. H., Phillips, K. A., et al. (2009) · Proceedings of the Royal Society B Biological Sciences · doi:10.1098/rspb.2009.1831 · Cited by 52
Yeung, R. K., Xiang, Z., Tsang, S., Li, R., Ho, T. Y. C., Li, Q., Hui, C.-K., Sham, P. C., Qiao, M.-Q., & Xue, H. (2018) · Translational Psychiatry · doi:10.1038/s41398-018-0176-9 · Cited by 51
Impairment of Dendrodendritic Inhibition in the Olfactory Bulb of APP/PS1 Mice
Li, W., Li, S., Shen, L., Wang, J., Wu, X., Li, J., Tu, C., Ye, X., & Ling, S. (2019) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2019.00002 · Cited by 51
Jones, A. F., & Sheets, P. L. (2020) · Cell Reports · doi:10.1016/j.celrep.2020.107729 · Cited by 51
Xia, Y., Zhang, Z.-Q., Lin, W.-P., Yan, J., Zhu, C., Yin, D., He, S., Su, Y., Xu, N., Caldwell, R. W., et al. (2020) · Neuropsychopharmacology · doi:10.1038/s41386-020-0743-7 · Cited by 52
Diurnal changes in perineuronal nets and parvalbumin neurons in the rat medial prefrontal cortex
Harkness, J. H., Gonzalez, A. E., Bushana, P. N., Jorgensen, E. T., Hegarty, D. M., Nardo, A. A. D., Prochiantz, A., Wisor, J. P., Aicher, S. A., Brown, T. E., et al. (2021) · Brain Structure and Function · doi:10.1007/s00429-021-02229-4 · Cited by 55
Chan, D., Suk, H., Jackson, B., Milman, N., Stark, D., Beach, S. D., & Tsai, L. (2021) · Journal of Internal Medicine · doi:10.1111/joim.13329 · Cited by 54
Neural Correlates of Auditory Hypersensitivity in Fragile X Syndrome
Razak, K. A., Binder, D. K., & Ethell, I. M. (2021) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2021.720752 · Cited by 55
Headley, D. B., & Weinberger, N. M. (2013) · Journal of Neuroscience · doi:10.1523/jneurosci.4915-12.2013 · Cited by 51
Alterations of perineuronal nets in the dorsolateral prefrontal cortex of neuropsychiatric patients
Alcaide, J., Guirado, R., Crespo, C., Blasco-Ibáñez, J. M., Varea, E., Sanjuan, J., & Nacher, J. (2019) · International Journal of Bipolar Disorders · doi:10.1186/s40345-019-0161-0 · Cited by 51
On Parallel Streams through the Mouse Dorsal Lateral Geniculate Nucleus
Denman, D. J., & Contreras, D. (2016) · Frontiers in Neural Circuits · doi:10.3389/fncir.2016.00020 · Cited by 52
Li, Y., Zhu, K., Li, N., Wang, X., Xiao, X., Li, L., Li, L., He, Y., Zhang, J., Wo, J., et al. (2021) · Alzheimer s Research & Therapy · doi:10.1186/s13195-021-00859-8 · Cited by 51
Nests of dividing neuroblasts sustain interneuron production for the developing human brain
Paredes, M. F., Mora, C., Flores-Ramirez, Q., Cebrián‐Silla, A., Dosso, A. D., Larimer, P., Chen, J., Kang, G., González-Granero, S., Garcia, E., et al. (2022) · Science · doi:10.1126/science.abk2346 · Cited by 50
Ting, J. T., & Feng, G. (2013) · Behavioural Brain Research · doi:10.1016/j.bbr.2013.02.037 · Cited by 50
Reduced Cortical BDNF Expression and Aberrant Memory inCarfKnock-Out Mice
McDowell, K. A., Hutchinson, A. N., Wong‐Goodrich, S. J. E., Presby, M. M., Su, D., Rodriguiz, R. M., Law, K., Williams, C. L., Wetsel, W. C., & West, A. E. (2010) · Journal of Neuroscience · doi:10.1523/jneurosci.3997-09.2010 · Cited by 52
Caught in the Net: Perineuronal Nets and Addiction
Slaker, M. L., Blacktop, J. M., & Sorg, B. A. (2016) · Neural Plasticity · doi:10.1155/2016/7538208 · Cited by 52
Grent-‘t-Jong, T., Rivolta, D., Sauer, A., Grube, M., Singer, W., Wibral, M., & Uhlhaas, P. J. (2016) · Schizophrenia Research · doi:10.1016/j.schres.2016.06.003 · Cited by 52
Zhen, J., Qian, Y., Weng, X., Su, W., Zhang, J., Cai, L., Dong, L., An, H., Su, R., Wang, J., et al. (2017) · Alzheimer s & Dementia Translational Research & Clinical Interventions · doi:10.1016/j.trci.2017.07.002 · Cited by 52
Yang, J., Prouvot, P.-H., Reyes‐Puerta, V., Stüttgen, M. C., Stroh, A., & Luhmann, H. J. (2017) · Cerebral Cortex · doi:10.1093/cercor/bhx261 · Cited by 50
Hippocampal Hyperactivity as a Druggable Circuit-Level Origin of Aberrant Salience in Schizophrenia
Kätzel, D., Wolff, A. R., Bygrave, A. M., & Bannerman, D. M. (2020) · Frontiers in Pharmacology · doi:10.3389/fphar.2020.486811 · Cited by 51
Ferando, I., & Mody, I. (2015) · Neuropharmacology · doi:10.1016/j.neuropharm.2014.09.010 · Cited by 49
Athilingam, J. C., Ben-Shalom, R., Keeshen, C. M., Sohal, V. S., & Bender, K. J. (2017) · eLife · doi:10.7554/elife.31991 · Cited by 49
Self-citationAbnormal interneuron development in disrupted-in-schizophrenia-1 L100P mutant mice
Lee, F. H., Zai, C. C., Cordes, S. P., Roder, J. C., & Wong, A. H. (2013) · Molecular Brain · doi:10.1186/1756-6606-6-20 · Cited by 49
Mechanisms Underlying Circuit Dysfunction in Neurodevelopmental Disorders
Exposito-Alonso, D., & Rico, B. (2022) · Annual Review of Genetics · doi:10.1146/annurev-genet-072820-023642 · Cited by 49
Steullet, P., Cabungcal, J.-H., Cuénod, M., & Do, K. Q. (2014) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2014.00244 · Cited by 49
Sohal, V. S. (2022) · American Journal of Psychiatry · doi:10.1176/appi.ajp.20220147 · Cited by 51
Self-citationThe optogenetic revolution in memory research
Goshen, I. (2014) · Trends in Neurosciences · doi:10.1016/j.tins.2014.06.002 · Cited by 51
Kotani, K., Yamaguchi, I., Yoshida, L., Jimbo, Y., & Ermentrout, B. (2014) · Journal of The Royal Society Interface · doi:10.1098/rsif.2014.0058 · Cited by 49
Brain oscillations reflecting pain-related behavior in freely moving rats
Peng, W., Xia, X., Yi, M., Huang, G., Zhang, Z., Iannetti, G. D., & Hu, L. (2017) · Pain · doi:10.1097/j.pain.0000000000001069 · Cited by 49
Gamma oscillations in the entorhinal-hippocampal circuit underlying memory and dementia
Nakazono, T., Jun, H., Blurton-Jones, M. M., Green, K. N., & Igarashi, K. M. (2018) · Neuroscience Research · doi:10.1016/j.neures.2018.02.002 · Cited by 52
Assogna, M., Casula, E. P., Borghi, I., Bonnì, S., Samà, D., Motta, C., Lorenzo, F. D., D’Acunto, A., Porrazzini, F., Minei, M., et al. (2020) · Journal of Alzheimer s Disease · doi:10.3233/jad-200426 · Cited by 51
Martín, J. Z. D. S., Donato, C., Peixoto, J., Aguirre, A., Choudhary, V., Stasi, A. M. D., Lourenço, J., Potier, M., & Bacci, A. (2020) · eLife · doi:10.7554/elife.58731 · Cited by 52
Step by step: cells with multiple functions in cortical circuit assembly
Cossart, R., & Garel, S. (2022) · Nature reviews. Neuroscience · doi:10.1038/s41583-022-00585-6 · Cited by 54
Investigating striatal function through cell-type-specific manipulations
Kreitzer, A. C., & Berke, J. D. (2011) · Neuroscience · doi:10.1016/j.neuroscience.2011.08.018 · Cited by 48
Holley, S. M., Joshi, P. R., Parievsky, A., Galvan, L., Chen, J., Fisher, Y. E., Huynh, M. N., Cepeda, C., & Levine, M. S. (2015) · eNeuro · doi:10.1523/eneuro.0008-14.2015 · Cited by 48
Craig, M. T., & McBain, C. J. (2015) · Journal of Neuroscience · doi:10.1523/jneurosci.4166-14.2015 · Cited by 50
Johnston, A. D., McBain, C. J., & Fisahn, A. (2014) · The Journal of Physiology · doi:10.1113/jphysiol.2014.279083 · Cited by 48
Survival of corticostriatal neurons by Rho/Rho-kinase signaling pathway
Kobayashi, K., Sano, H., Kato, S., Kuroda, K., Nakamuta, S., Isa, T., Nambu, A., Kaibuchi, K., & Kobayashi, K. (2016) · Neuroscience Letters · doi:10.1016/j.neulet.2016.07.020 · Cited by 48
Converging evidence for gamma synchrony deficits in schizophrenia
Roach, B. J., Ford, J. M., Hoffman, R. E., & Mathalon, D. H. (2013) · Supplements to Clinical neurophysiology · doi:10.1016/b978-0-7020-5307-8.00011-9 · Cited by 48
Hameed, M. Q., Hsieh, T.-H., Morales-Quezada, L., Lee, H. H. C., Damar, U., MacMullin, P., Hensch, T. K., & Rotenberg, A. (2018) · Cerebral Cortex · doi:10.1093/cercor/bhy328 · Cited by 48
Huang, M., Huang, C. W., Harrington, D. L., Nichols, S., Robb, A., Angeles‐Quinto, A., Le, L., Rimmele, C. T., Drake, A., Song, T., et al. (2019) · Cerebral Cortex · doi:10.1093/cercor/bhz087 · Cited by 50
Roach, B. J., D’Souza, D. C., Ford, J. M., & Mathalon, D. H. (2019) · NeuroImage Clinical · doi:10.1016/j.nicl.2019.101878 · Cited by 48
Hyperexcitable Parvalbumin Interneurons Render Hippocampal Circuitry Vulnerable to Amyloid Beta
Hijazi, S., Heistek, T. S., van der Loo, R. J., Mansvelder, H. D., Smit, A. B., & van Kesteren, R. E. (2020) · iScience · doi:10.1016/j.isci.2020.101271 · Cited by 50
Wang, H., Xu, X., Xu, X., Gao, J., & Zhang, T. (2020) · Neurochemical Research · doi:10.1007/s11064-020-03102-2 · Cited by 50
McNally, J. M., McCarley, R. W., & Brown, R. E. (2013) · Current Psychiatry Reports · doi:10.1007/s11920-012-0346-z · Cited by 47
Spontaneous variability in gamma dynamics described by a damped harmonic oscillator driven by noise
Spyropoulos, G., Saponati, M., Dowdall, J. R., Schölvinck, M. L., Bosman, C. A., Lima, B., Peter, A., Onorato, I., Klon-Lipok, J., Roese, R., et al. (2022) · Nature Communications · doi:10.1038/s41467-022-29674-x · Cited by 52
Exploring intermediate phenotypes with EEG: Working memory dysfunction in schizophrenia
Haenschel, C., & Linden, D. E. J. (2010) · Behavioural Brain Research · doi:10.1016/j.bbr.2010.08.045 · Cited by 54
Hartung, H., Cichon, N., Feo, V. D., Riemann, S., Schildt, S., Lindemann, C., Mulert, C., Gogos, J. A., & Hanganu‐Opatz, I. L. (2016) · Cerebral Cortex · doi:10.1093/cercor/bhw274 · Cited by 47
Burke, K. J., Keeshen, C. M., & Bender, K. J. (2018) · Neuron · doi:10.1016/j.neuron.2018.07.030 · Cited by 49
Wang, X., Pinto-Duarte, A., Sejnowski, T. J., & Behrens, M. M. (2013) · Antioxidants & Redox Signaling · doi:10.1089/ars.2012.4907 · Cited by 46
Durá-Bernal, S., Neymotin, S. A., Suter, B. A., Dacre, J., Moreira, J. V. S., Urdapilleta, E., Schiemann, J. M., Duguid, I., Shepherd, G. M., & Lytton, W. W. (2022) · Cell Reports · doi:10.1016/j.celrep.2023.112574 · Cited by 48
Bringing Imaging Biomarkers Into Clinical Reality in Psychiatry
Etkin, A., & Mathalon, D. H. (2024) · JAMA Psychiatry · doi:10.1001/jamapsychiatry.2024.2553 · Cited by 46
Kaliukhovich, D. A., & Vogels, R. (2012) · Journal of Neurophysiology · doi:10.1152/jn.00059.2012 · Cited by 47
Bovetti, S., & Fellin, T. (2014) · Journal of Neuroscience Methods · doi:10.1016/j.jneumeth.2014.12.002 · Cited by 48
Altered brain connectivity in 3-to 7-year-old children with autism spectrum disorder
Kikuchi, M., Shitamichi, K., Yoshimura, Y., Ueno, S., Hiraishi, H., Hirosawa, T., Munesue, T., Nakatani, H., Tsubokawa, T., Haruta, Y., et al. (2013) · NeuroImage Clinical · doi:10.1016/j.nicl.2013.03.003 · Cited by 50
Vascak, M., Jin, X., Jacobs, K. M., & Povlishock, J. T. (2017) · Cerebral Cortex · doi:10.1093/cercor/bhx058 · Cited by 50
Grent-‘t-Jong, T., Gajwani, R., Groß, J., Gumley, A. I., Krishnadas, R., Lawrie, S. M., Schwannauer, M., Schultze‐Lutter, F., & Uhlhaas, P. J. (2020) · JAMA Psychiatry · doi:10.1001/jamapsychiatry.2020.0284 · Cited by 46
Prefrontal-amygdalar oscillations related to social behavior in mice
Kuga, N., Abe, R., Takano, K., Ikegaya, Y., & Sasaki, T. (2022) · eLife · doi:10.7554/elife.78428 · Cited by 47
Leicht, G., Andreou, C., Polomac, N., Lanig, C. R., Schöttle, D., Lambert, M., & Mulert, C. (2015) · The World Journal of Biological Psychiatry · doi:10.3109/15622975.2015.1017605 · Cited by 46
Ueno, H., Suemitsu, S., Okamoto, M., Matsumoto, Y., & Ishihara, T. (2017) · Neuroscience · doi:10.1016/j.neuroscience.2017.04.041 · Cited by 49
Xenos, D., Kamceva, M., Tomasi, S., Cardin, J. A., Schwartz, M. L., & Vaccarino, F. M. (2017) · Cerebral Cortex · doi:10.1093/cercor/bhx173 · Cited by 48
A neural circuit for gamma-band coherence across the retinotopic map in mouse visual cortex
Hakim, R., Shamardani, K., & Adesnik, H. (2018) · eLife · doi:10.7554/elife.28569 · Cited by 47
Cabungcal, J.-H., Steullet, P., Kraftsik, R., Cuénod, M., & Kim, Q. (2019) · Schizophrenia Research · doi:10.1016/j.schres.2019.02.017 · Cited by 46
Firing rate models for gamma oscillations
Keeley, S., Byrne, Á., Fenton, A. A., & Rinzel, J. (2019) · Journal of Neurophysiology · doi:10.1152/jn.00741.2018 · Cited by 47
Zhang, B., Yang, X., Ye, L., Liu, R., Ye, B., Du, W., Shen, F., Li, Q., Guo, F., Liu, J., et al. (2020) · Neuropharmacology · doi:10.1016/j.neuropharm.2020.108382 · Cited by 47
Berto, S., Treacher, A., Caglayan, E., Luo, D., Haney, J. R., Gandal, M. J., Geschwind, D. H., Montillo, A., & Konopka, G. (2022) · Nature Communications · doi:10.1038/s41467-022-31053-5 · Cited by 48
Electrophysiological Endophenotypes for Schizophrenia
Owens, E. M., Bachman, P., Glahn, D. C., & Bearden, C. E. (2016) · Harvard Review of Psychiatry · doi:10.1097/hrp.0000000000000110 · Cited by 50
Cellular Anatomy of the Mouse Primary Motor Cortex
Muñoz-Castañeda, R., Zingg, B., Matho, K. S., Wang, Q., Chen, X., Foster, N. N., Narasimhan, A., Li, A., Hirokawa, K. E., Huo, B., et al. (2020) · doi:10.1101/2020.10.02.323154 · Cited by 270
Wang, Y., Zan, G., Xu, C., Li, X., Shu, X., Yao, S.-Y., Xu, X.-S., Qiu, X., Chen, Y., Jin, K., et al. (2023) · Nature Communications · doi:10.1038/s41467-023-43636-x · Cited by 46
Metadata
- Authors
- Sohal, V. S., Zhang, F., Yizhar, O., & Deisseroth, K.
- Affiliations
- Stanford University (US)
- Corresponding author
- Deisseroth, Karl
- Venue
- Nature
- Published
- 2009-04-26
- Volume
- 459
- Issue
- 7247
- Pages
- 698-702
- ISSN
- 0028-0836 (ISSN-L)
- 1476-4687
- PMC
- PMC3969859
- OpenAlex
- W2047347093
- Cited by
- 2,606
- References
- 31
- Citations by year
- 2026: 118 · 2025: 143 · 2024: 155 · 2023: 138 · 2022: 169 · 2021: 183 · 2020: 190 · 2019: 143 · 2018: 154 · 2017: 172 · 2016: 171 · 2015: 158 · 2014: 143 · 2013: 151 · 2012: 136
- FWCI
- 67.26
- Type
- journal article
- Language
- en
- Open access
- green
- europepmc.org
- Licence
- www.springer.com/tdm (tdm)
- Locations
- Nature (publishedVersion)
- PubMed (publishedVersion)
- Europe PMC (PubMed Central) (acceptedVersion)
- PubMed Central (acceptedVersion)
- RePEc: Research Papers in Economics (submittedVersion)
- Funders
- National Institute of Neurological Disorders and Stroke (F31NS059160)
- Topics
- Life Sciences › Neuroscience › Cognitive Neuroscience › Neural dynamics and brain function
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neuroscience and Neuropharmacology Research
- Life Sciences › Neuroscience › Cognitive Neuroscience › Memory and Neural Mechanisms
- Keywords
- parvalbumin interneurons, gamma oscillations, fast-spiking interneurons, cortical circuits, optogenetics, signal-to-noise ratio, sensory input, cortical inhibition, schizophrenia, autism spectrum disorder, neocortex, neuronal synchronization, information processing, attention, signal decoding
- MeSH terms
- Animals, Cell Line, Cerebral Cortex, Cortical Synchronization, Electrophysiology, Evoked Potentials, Interneurons, Parvalbumins, Periodicity, Photic Stimulation, Signal Transduction, Prefrontal Cortex, Neocortex, Mice
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