Cited by 2,786Neural dynamics and brain functionVisual perception and processing mechanismsNeuroscience and Neuropharmacology Research

Modulation of Oscillatory Neuronal Synchronization by Selective Visual Attention

Fries, Pascal, Reynolds, John H., Rorie, Alan E., Desimone, Robert·2001·Science

Abstract

In crowded visual scenes, attention is needed to select relevant stimuli. To study the underlying mechanisms, we recorded neurons in cortical area V4 while macaque monkeys attended to behaviorally relevant stimuli and ignored distracters. Neurons activated by the attended stimulus showed increased gamma-frequency (35 to 90 hertz) synchronization but reduced low-frequency (<17 hertz) synchronization compared with neurons at nearby V4 sites activated by distracters. Because postsynaptic integration times are short, these localized changes in synchronization may serve to amplify behaviorally relevant signals in the cortex.

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Crossref · 10.1126/science.1055465

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Authors
Fries, P., Reynolds, J. H., Rorie, A. E., & Desimone, R.
Affiliations
National Institutes of Health (US)
Corresponding author
Fries, Pascal
Venue
Science
Published
2001-02-23
Volume
291
Issue
5508
Pages
1560-1563
ISSN
  • 0036-8075 (ISSN-L)
  • 1095-9203
OpenAlex
W2170814877
Cited by
2,786
References
35
Citations by year
2026: 41 · 2025: 63 · 2024: 78 · 2023: 75 · 2022: 102 · 2021: 123 · 2020: 118 · 2019: 155 · 2018: 116 · 2017: 118 · 2016: 121 · 2015: 159 · 2014: 128 · 2013: 145 · 2012: 144
FWCI
41.11
Type
journal article
Language
en
Open access
closed
Locations
  • Science (publishedVersion)
  • PubMed (publishedVersion)
  • MPG.PuRe (Max Planck Society) (submittedVersion)
  • Radboud Repository (Radboud University) (submittedVersion)
Topics
  • Life Sciences › Neuroscience › Cognitive Neuroscience › Neural dynamics and brain function
  • Life Sciences › Neuroscience › Cognitive Neuroscience › Visual perception and processing mechanisms
  • Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neuroscience and Neuropharmacology Research
Keywords
visual attention, neuronal synchronization, gamma oscillations, low-frequency oscillations, area V4, macaque cortex, distractor suppression, signal amplification
MeSH terms
Action Potentials, Animals, Attention, Cues, Electrophysiology, Fixation, Ocular, Macaca, Neurons, Photic Stimulation, Visual Cortex, Visual Perception

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