The Polycomb complex PRC2 and its mark in life
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Items 501–600 of 1,009
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- Role of Histone Post-Translational Modifications in Inflammatory DiseasesYingying Lin, Ting Qiu, Guifeng Wei, Yueyue Que, Wenxin Wang, Yichao Kong, Tian Xie, Xiabin Chen · 2022 · Frontiers in Immunology
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- Driver mutations in acute myeloid leukemiaAshwin Kishtagari, Ross L. Levine, Aaron D. Viny · 2020 · Current Opinion in Hematology
- BAHCC1 binds H3K27me3 via a conserved BAH module to mediate gene silencing and oncogenesisHuitao Fan, Jiuwei Lu, Yiran Guo, Dongxu Li, Zhimin Zhang, Yi‐Hsuan Tsai, Wen‐Chieh Pi, Jeong Hyun Ahn, Weida Gong, Yu Xiang et al. · 2020 · Nature Genetics
- Functions and underlying mechanisms of lncRNA HOTAIR in cancer chemotherapy resistanceChunming Zhu, Xia Wang, Yuan Wang, Kefeng Wang · 2022 · Cell Death Discovery
- Comparative methylome analysis in solid tumors reveals aberrant methylation at chromosome 6p in nasopharyngeal carcinomaWei Dai, Arthur Kwok Leung Cheung, Josephine Mun Yee Ko, Yue Cheng, Hong Zheng, Roger Kai‐Cheong Ngan, Wai Tong Ng, Anne W.M. Lee, Chun Chung Yau, Victor Ho-Fun Lee et al. · 2015 · Cancer Medicine
- EZH2 suppression in glioblastoma shifts microglia toward M1 phenotype in tumor microenvironmentYatao Yin, Shuwei Qiu, Xiangpen Li, Bo Huang, Yun Xu, Ying Peng · 2017 · Journal of Neuroinflammation
- Effector gene silencing mediated by histone methylation underpins host adaptation in an oomycete plant pathogenLiyuan Wang, Han Chen, JiangJiang Li, Haidong Shu, Xiangxue Zhang, Yuanchao Wang, Brett M. Tyler, Suomeng Dong · 2019 · Nucleic Acids Research
- A New lncRNA, APTR, Associates with and Represses the CDKN1A/p21 Promoter by Recruiting Polycomb ProteinsMasamitsu Negishi, Somsakul Pop Wongpalee, Sukumar Sarkar, Jong-Hoon Park, Kyung Yong Lee, Yoshiyuki Shibata, Brian J. Reon, Roger Abounader, Yutaka Suzuki, Sumio Sugano et al. · 2014 · PLoS ONE
- Binding of PHF1 Tudor to H3K36me3 enhances nucleosome accessibilityCatherine A. Musselman, Matthew D. Gibson, Erik W. Hartwick, Justin A. North, Jovylyn Gatchalian, Michael Guy Poirier, Tatiana G. Kutateladze · 2013 · Nature Communications
- BCOR regulates myeloid cell proliferation and differentiationQi Cao, Micah D. Gearhart, Sigal Gery, Seyedmehdi Shojaee, Henry He Yang, Haibo Sun, D-c Lin, J-w Bai, Monica Diane Mead, Z Zhao et al. · 2016 · Leukemia
- Hypoxia-Inducible Histone Lysine Demethylases: Impact on the Aging Process and Age-Related DiseasesAntero Salminen, Kaarniranta Kai, Anu Kauppinen · 2016 · Aging and Disease