The Polycomb complex PRC2 and its mark in life

Cited by (1,009)

Items 301–400 of 1,009

1. UTX Mutations in Human Cancer
   Lu Wang, Ali Shilatifard · 2019 · Cancer Cell
2. The histone H3 Lys 27 demethylase JMJD3 regulates gene expression by impacting transcriptional elongation
   Shuzhen Chen, Jian Ma, Feizhen Wu, Li-jun Xiong, Honghui Ma, Wenqi Xu, Ruitu Lyu, Xiaodong Li, Judit Villén, Steven P. Gygi et al. · 2012 · Genes & Development
3. MLL3/MLL4/COMPASS Family on Epigenetic Regulation of Enhancer Function and Cancer
   Sze, Christie C., Shilatifard, Ali · 2016 · Cold Spring Harbor Perspectives in Medicine
4. Polycomb repressive complex 2 structure with inhibitor reveals a mechanism of activation and drug resistance
   Alexei Brooun, K.S. Gajiwala, Ya‐Li Deng, Wei Liu, Ben Bolaños, Patrick Bingham, You-Ai He, Wade C. Diehl, Nicole Grable, Pei‐Pei Kung et al. · 2016 · Nature Communications
5. The cancer COMPASS: navigating the functions of MLL complexes in cancer
   David J. Ford, Andrew K. Dingwall · 2015 · Cancer Genetics
6. RNA-dependent stabilization of SUV39H1 at constitutive heterochromatin
   Whitney L. Johnson, William T. Yewdell, Jason C. Bell, Shannon M. McNulty, Zachary Duda, Rachel J. Waugh O'Neill, Beth A. Sullivan, Aaron F. Straight · 2017 · eLife
7. Global H3K27 trimethylation and EZH2 abundance in breast tumor subtypes
   Karolina Holm, Dorthe Aamand Grabau, Kristina Lövgren, S. Aradottir, Sofia K. Gruvberger-Saal, Jillian Howlin, Lao H. Saal, Stephen P. Ethier, Pär‐Ola Bendahl, Olle Stål et al. · 2012 · Molecular Oncology
8. Mammalian SWI/SNF complexes in cancer: emerging therapeutic opportunities
   Roodolph St. Pierre, Cigall Kadoch · 2017 · Current Opinion in Genetics & Development
9. Histone Methylation by SET Domain Proteins in Fungi
   Michael Freitag · 2017 · Annual Review of Microbiology
10. Epigenetic Drug Discovery: Targeting DNA Methyltransferases
    Jason M. Foulks, K. Mark Parnell, Rebecca N. Nix, Suzanna Chau, Krzysztof Świerczek, Michael John Saunders, Kevin Wright, Thomas F. Hendrickson, Koc-Kan Ho, Michael V. McCullar et al. · 2011 · SLAS DISCOVERY
11. Regulation of Skeletal Muscle Stem Cell Quiescence by Suv4-20h1-Dependent Facultative Heterochromatin Formation
    Verawan Boonsanay, Ting Zhang, Angelina M. Georgieva, Sawa Kostin D, Hui Qi, Xuejun Yuan, Yonggang Zhou, Thomas W Braun · 2015 · Cell stem cell
12. c-Myc-Mediated Epigenetic Silencing of MicroRNA-101 Contributes to Dysregulation of Multiple Pathways in Hepatocellular Carcinoma
    Lei Wang, Xiang Zhang, Lintao Jia, Si-Jun Hu, Jing Zhao, Jiandong Yang, Weihong Wen, Zhe Wang, Tao Wang, Jun Zhao et al. · 2013 · Hepatology
13. Epigenetic regulation of autophagy by the methyltransferase EZH2 through an MTOR-dependent pathway
    Fu-Zheng Wei, Ziyang Cao, Xi Wang, Hui Wang, Mu-Yan Cai, Tingting Li, Naoko Hattori, Donglai Wang, Yipeng Du, Boyan Song et al. · 2015 · Autophagy
14. Stress, novel sex genes, and epigenetic reprogramming orchestrate socially controlled sex change
    Erica V. Todd, Oscar Ortega‐Recalde, Hui Liu, Melissa S. Lamm, Kim Rutherford, Hugh Cross, Michael A. Black, Olga Kardailsky, Jennifer A. Marshall Graves, Timothy A. Hore et al. · 2019 · Science Advances
15. Mechanisms by which SMARCB1 loss drives rhabdoid tumor growth
    Kimberly Hyunjung Kim, Charles W.M. Roberts · 2014 · Cancer Genetics
16. Genome-wide high resolution parental-specific DNA and histone methylation maps uncover patterns of imprinting regulation in maize
    Mei Zhang, Shaojun Xie, Xiaomei Dong, Xin Zhao, Biao Zeng, Jian Chen, Hui Li, Weilong Yang, Hainan Zhao, Gaokui Wang et al. · 2013 · Genome Research
17. Critical role of histone demethylase Jmjd3 in the regulation of CD4+ T-cell differentiation
    Qingtian Li, Jia Zou, Mingjun Wang, Xilai Ding, Iouri Chepelev, Xikun Zhou, Wei Zhao, Gang Wei, Jun Cui, Keji Zhao et al. · 2014 · Nature Communications
18. Characterization of the EZH2-MMSET Histone Methyltransferase Regulatory Axis in Cancer
    Irfan Ahmed Asangani, Bushra Ateeq, Qi Cao, Lois M. Dodson, Mithil B. Pandhi, Lakshmi Priya Kunju, Rohit Mehra, Robert J. Lonigro, Javed Siddiqui, Nallasivam Palanisamy et al. · 2012 · Molecular Cell
19. Potential energy landscapes identify the information-theoretic nature of the epigenome
    Garrett Jenkinson, Elisabet Pujadas, John I. Goutsias, Andrew P. Feinberg · 2017 · Nature Genetics
20. LncRNA MALAT1 facilitates inflammasome activation via epigenetic suppression of Nrf2 in Parkinson’s disease
    Li-Jun Cai, Li Tu, Xiao-Mo Huang, Jia Huang, Nan Qiu, Guanghong Xie, Jian-Xiong Liao, Wei Du, Yingyue Zhang, Jinyong Tian · 2020 · Molecular Brain
21. Antagonism between MES-4 and Polycomb Repressive Complex 2 Promotes Appropriate Gene Expression in C. elegans Germ Cells
    Laura J. Gaydos, Andreas Rechtsteiner, Thea A. Egelhofer, Coleen R. Carroll, Susan Strome · 2012 · Cell Reports
22. Identification of EZH2 and EZH1 Small Molecule Inhibitors with Selective Impact on Diffuse Large B Cell Lymphoma Cell Growth
    Shivani Garapaty, Christopher G. Nasveschuk, Alexandre Gagnon, Eric Y. Chan, Péter Sandy, Jennifer Busby, Srividya Balasubramanian, Robert Campbell, Feng Zhao, Louise Bergeron et al. · 2013 · Chemistry & Biology
23. Fusion of the ZC3H7B and BCOR genes in endometrial stromal sarcomas carrying an X;22‐translocation
    Ioannis Panagopoulos, Jim Thorsen, Ludmila Gorunova, Lisbeth Haugom, Bodil Bjerkehagen, Ben Davidson, Sverre Heim, Francesca Micci · 2013 · Genes Chromosomes and Cancer
24. Histone Variants Enriched in Oocytes Enhance Reprogramming to Induced Pluripotent Stem Cells
    Toshie Shinagawa, Tsuyoshi Takagi, Daisuke Tsukamoto, Chinatsu Tomaru, Linh Huynh, Sivaraman Padavattan, Thirumananseri Kumarevel, Kimiko Inoue, Ryuichiro Nakato, Yuki Katou et al. · 2014 · Cell stem cell
25. Epigenetics in liver disease
    Mann, Derek A. · 2014 · Hepatology
26. Jmjd3 Inhibits Reprogramming by Upregulating Expression of INK4a/Arf and Targeting PHF20 for Ubiquitination
    Wei Zhao, Qingtian Li, Stephen D. Ayers, Yifeng Gu, Zhong Q. Shi, Qingyuan Zhu, Yidong Chen, Helen Y. Wang, Rong‐Fu Wang · 2013 · Cell
27. Developments of CRBN-based PROTACs as potential therapeutic agents
    Chao Wang, Yujing Zhang, Yudong Wu, Dongming Xing · 2021 · European Journal of Medicinal Chemistry
28. EZH2 Protein Expression Associates with the Early Pathogenesis, Tumor Progression, and Prognosis of Non–Small Cell Lung Carcinoma
    Carmen Behrens, Luisa Maren Solis, Heather Yan Lin, Ping Yuan, Ximing Tang, Humam N. Kadara, Erick Marcelo Riquelme, Héctor Galindo, César A. Moran, Neda Kalhor et al. · 2013 · Clinical Cancer Research
29. Recurrent Rearrangement of the PHF1 Gene in Ossifying Fibromyxoid Tumors
    Samuel Gebré‐Medhin, Karolin H. Nord, Emely Möller, Nils Mandahl, Linda Magnusson, Jenny Nilsson, Vickie Y. Jo, Fredrik Vult von Steyern, Otte Brosjö, Olle Larsson et al. · 2012 · American Journal Of Pathology
30. The Polycomb-Dependent Epigenome Controls β Cell Dysfunction, Dedifferentiation, and Diabetes
    Lu, Tess Tsai-Hsiu, Heyne, Steffen, Dror, Erez, Casas, Eduard, Leonhardt, Laura, Boenke, Thorina, Yang, Chih-Hsiang, Sagar, Arrigoni, Laura, Dalgaard, Kevin et al. · 2018 · Cell Metabolism
31. Methylome analysis and integrative profiling of human HCCs identify novel protumorigenic factors
    Olaf Neumann, Miriam Kesselmeier, Robert Geffers, Rossella Pellegrino, Bernhard Radlwimmer, Katrin Hoffmann, Volker Ehemann, Peter Schemmer, Peter Schirmacher, Justo Lorenzo Bermejo et al. · 2012 · Hepatology
32. The Chromatin Remodelers PKL and PIE1 Act in an Epigenetic Pathway That Determines H3K27me3 Homeostasis in Arabidopsis
    Benjamin C. Carter, Brett Bishop, Kwok Ki Ho, Ru Nan Huang, Wei Qiang Jia, Heng Zhang, Pete E. Pascuzzi, Roger B. Deal, Joe Ogas · 2018 · The Plant Cell
33. Developmental Control of Polycomb Subunit Composition by GATA Factors Mediates a Switch to Non-Canonical Functions
    Jian Xu, Zhen Shao, Dan Li, Huafeng Xie, Woojin Kim, Jialiang Huang, Jordan E. Taylor, Luca Pinello, Kimberly Glass, Jacob D. Jaffe et al. · 2015 · Molecular Cell
34. BAP1 complex promotes transcription by opposing PRC1-mediated H2A ubiquitylation
    Antoine Campagne, Ming-Kang Lee, Dina Zielinski, Audrey Michaud, Stéphanie Le Corre, Florent Dingli, Hong Chen, Lara Zorro Shahidian, Ivaylo Vassilev, Nicolas Servant et al. · 2019 · Nature Communications
35. Development of secondary mutations in wild-type and mutant EZH2 alleles cooperates to confer resistance to EZH2 inhibitors
    Gibaja, V, Shen, F, Harari, J, Korn, J, Ruddy, D, Saenz-Vash, V, Zhai, H, Rejtar, T, Paris, C G, Yu, Z et al. · 2016 · Oncogene
36. The H3K27me3 demethylase UTX in normal development and disease
    Joni Van der Meulen, Frank Speleman, Pieter Van Vlierberghe · 2014 · Epigenetics
37. T-cell receptor-based therapy: an innovative therapeutic approach for solid tumors
    Apostolia Maria Tsimberidou, Karlyle Van Morris, Henry Hiep Vo, Stephen Eck, Yu‐Feng Lin, Jorge Mauricio Rivas, Börje S. Andersson · 2021 · Journal of Hematology & Oncology
38. EZH2 depletion potentiates MYC degradation inhibiting neuroblastoma and small cell carcinoma tumor formation
    Liyuan Wang, Chan Chen, Zemin Song, Honghong Wang, Minghui Ye, Donghai Wang, Wenqian Kang, Hudan Liu, Guoliang Qing · 2022 · Nature Communications
39. GANT-61 inhibits pancreatic cancer stem cell growth in vitro and in NOD/SCID/IL2R gamma null mice xenograft
    Junsheng Fu, Mariana Rodova, Sanjit Kumer Roy, Jay P. Sharma, Karan P. Singh, Rakesh K. Srivastava, Sharmila Shankar · 2012 · Cancer Letters
40. A Family of Vertebrate-Specific Polycombs Encoded by the LCOR/LCORL Genes Balance PRC2 Subtype Activities
    Eric Conway, Emilia Jerman, Evan Healy, Shinsuke Ito, Daniel Holoch, Giorgio Oliviero, Orla Deevy, Eleanor Glancy, Darren J. Fitzpatrick, Marlena Mucha et al. · 2018 · Molecular Cell
41. EZH2 Inhibitor Efficacy in Non-Hodgkin’s Lymphoma Does Not Require Suppression of H3K27 Monomethylation
    William D. Bradley, Shilpi Arora, Jennifer Busby, Srividya Balasubramanian, Victor S. Gehling, Christopher G. Nasveschuk, Rishi G. Vaswani, Chih-Chi Yuan, Charlie Hatton, Feng Zhao et al. · 2014 · Chemistry & Biology
42. Clinicopathologic characteristics of poorly differentiated chordoma
    Angela R. Shih, Gregory Michael Cote, Ivan A. Chebib, Edwin Choy, Thomas F. DeLaney, Vikram Deshpande, Francis John Hornicek, Ruoyu Miao, Joseph Hasbrouck Schwab, G. Petur Nielsen et al. · 2018 · Modern Pathology
43. Non-core Subunits of the PRC2 Complex Are Collectively Required for Its Target-Site Specificity
    Jonas Westergaard Højfeldt, Lin Hedehus, Anne Laugesen, Tülin Tatar, Laura Wiehle, Kristian Helin · 2019 · Molecular Cell
44. RNA is essential for PRC2 chromatin occupancy and function in human pluripotent stem cells
    Yicheng Long, Taeyoung Hwang, Anne R. Gooding, Karen J. Goodrich, John L. Rinn, Thomas R. Cech · 2020 · Nature Genetics
45. Dynamics of genome architecture and chromatin function during human B cell differentiation and neoplastic transformation
    Roser Vilarrasa‐Blasi, Paula Soler-Vila, Núria Verdaguer-Dot, Núria Russiñol, Marco Di Stefano, Vicente Chapaprieta, Guillem Clot, Irene Farabella, Pol Cuscó, Marta Kulis et al. · 2021 · Nature Communications
46. Exploiting the Epigenome to Control Cancer-Promoting Gene-Expression Programs
    Gerard L. Brien, Daria G. Valerio, Scott A. Armstrong · 2016 · Cancer Cell
47. Epigenetic regulation of epithelial–mesenchymal transition
    Lidong Sun, Jia Fang · 2016 · Cellular and Molecular Life Sciences
48. Epigenetic Reprogramming Sensitizes CML Stem Cells to Combined EZH2 and Tyrosine Kinase Inhibition
    Mary T. Scott, Koorosh Korfi, Peter Saffrey, Lisa E. M. Hopcroft, Ross Kinstrie, Francesca Pellicano, Carla Guenther, Paolo Gallipoli, Michelle Maria Araujo Cruz, Karen M. Dunn et al. · 2016 · Cancer Discovery
49. Mechanisms of resistance to EZH2 inhibitors in diffuse large B-cell lymphomas
    Malik Bisserier, Narendra Wajapeyee · 2018 · Blood
50. Hepatitis B protein HBx binds the DLEU2 lncRNA to sustain cccDNA and host cancer-related gene transcription
    Debora Salerno, Letizia Chiodo, Vincenzo Alfano, Océane Floriot, Grazia Cottone, Alexia Paturel, Matteo Pallocca, Marie‐Laure Plissonnier, S. Jeddari, Laura Belloni et al. · 2020 · Gut
51. PLK1 and HOTAIR Accelerate Proteasomal Degradation of SUZ12 and ZNF198 during Hepatitis B Virus–Induced Liver Carcinogenesis
    Hao Zhang, Ahmed Diab, Huitao Fan, Saravana Kumar Kailasam Mani, Ronald Loral Hullinger, Philippe Merle, OURANIA M. ANDRISANI · 2015 · Cancer Research
52. RYBP stimulates PRC1 to shape chromatin-based communication between Polycomb repressive complexes
    Nathan R. Rose, Hamish W. King, Neil P. Blackledge, Nadezda A. Fursova, Katherine JI Ember, Román Fischer, Benedikt Mathias Kessler, Robert J. Klose · 2016 · eLife
53. Wapl repression by Pax5 promotes V gene recombination by Igh loop extrusion
    Louisa Hill, Anja Ebert, Markus Jaritz, Gordana Wutz, Kota Nagasaka, Hiromi Tagoh, Daniela Kostanova‐Poliakova, Karina Schindler, Qiong Sun, Peter Bönelt et al. · 2020 · Nature
54. Structure of the Catalytic Domain of EZH2 Reveals Conformational Plasticity in Cofactor and Substrate Binding Sites and Explains Oncogenic Mutations
    Hong Wu, Hong Zeng, Aiping Dong, Fengling Li, Hao He, Guillermo A. Senisterra, Alma Seitova, Shili Duan, Peter J. Brown, Masoud Vedadi et al. · 2013 · PLoS ONE
55. Distinct Stimulatory Mechanisms Regulate the Catalytic Activity of Polycomb Repressive Complex 2
    Chul‐Hwan Lee, Marlene Holder, Daniel Grau, Ricardo Saldaña-Meyer, Jia-Ray Yu, Rais A. Ganai, Jenny Zhang, Miao Wang, Gary LeRoy, Marc‐Werner Dobenecker et al. · 2018 · Molecular Cell
56. PRC2 and SWI/SNF Chromatin Remodeling Complexes in Health and Disease
    Cigall Kadoch, Robert A. Copeland, Heike Keilhack · 2016 · Biochemistry
57. Deletion of the Polycomb-Group Protein EZH2 Leads to Compromised Self-Renewal and Differentiation Defects in Human Embryonic Stem Cells
    Adam Collinson, Amanda J. Collier, Natasha P. Morgan, Arnold R. Sienerth, Tamir Chandra, Simon Andrews, Peter J. Rugg‐Gunn · 2016 · Cell Reports
58. MATCHER: manifold alignment reveals correspondence between single cell transcriptome and epigenome dynamics
    Welch, Joshua D., Hartemink, Alexander J., Prins, Jan F. · 2017 · Genome Biology
59. Single-cell multi-omics of human clonal hematopoiesis reveals that DNMT3A R882 mutations perturb early progenitor states through selective hypomethylation
    Nam, Anna S., Dusaj, Neville, Izzo, Franco, Murali, Rekha, Myers, Robert M., Mouhieddine, Tarek H., Sotelo, Jesus, Benbarche, Salima, Waarts, Michael, Gaiti, Federico et al. · 2022 · Nature Genetics
60. Decrypting noncoding RNA interactions, structures, and functional networks
    Muller Fabbri, Leonard Girnita, Gabriele Varani, George Adrian Calin · 2019 · Genome Research
61. Acquired Tissue-Specific Promoter Bivalency Is a Basis for PRC2 Necessity in Adult Cells
    Jadhav, Unmesh, Nalapareddy, Kodandaramireddy, Saxena, Madhurima, O’Neill, Nicholas K., Pinello, Luca, Yuan, Guo-Cheng, Orkin, Stuart H., Shivdasani, Ramesh A. · 2016 · Cell
62. Epigenome-wide meta-analysis of DNA methylation differences in prefrontal cortex implicates the immune processes in Alzheimer’s disease
    Zhang, Lanyu, Silva, Tiago C., Young, Juan I., Gomez, Lissette, Schmidt, Michael A., Hamilton-Nelson, Kara L., Kunkle, Brian W., Chen, Xi, Martin, Eden R., Wang, Lily · 2020 · Nature Communications
63. Emerging roles for Polycomb proteins in cancer
    Pasini, Diego, Di Croce, Luciano · 2016 · Current Opinion in Genetics & Development
64. LncRNA H19 inhibits autophagy by epigenetically silencing of DIRAS3 in diabetic cardiomyopathy
    Chuanjun Zhuo, Ronghuan Jiang, Xiaodong Lin, Mingjing Shao · 2016 · Oncotarget
65. Polycomb function during oogenesis is required for mouse embryonic development
    Eszter Pósfai, Rico Kunzmann, Vincent Brochard, Juliette Salvaing, Erik Cabuy, Tim C. Roloff, Zichuan Liu, Mathieu Tardat, Maarten van Lohuizen, Miguel Vidal et al. · 2012 · Genes & Development
66. Universal DNA methylation age across mammalian tissues
    A.T. Lu, Zhe Fei, Amin Haghani, Todd R. Robeck, Joseph Alan Zoller, Chengzhang Li, Robert Lowe, Qi Jiang Yan, Joshua Zhang, H. Vu et al. · 2021 · bioRxiv (Cold Spring Harbor Laboratory)
67. Decoding the function of bivalent chromatin in development and cancer
    Dhirendra Kumar, Senthilkumar Cinghu, Andrew Oldfield, Pengyi Yang, Raja Jothi · 2021 · Genome Research
68. Epigenetic treatment of pancreatic cancer: is there a therapeutic perspective on the horizon?
    Elisabeth Heßmann, Steven A. Johnsen, Jens Thomas Siveke, Volker Ellenrieder · 2016 · Gut
69. Optimization of Orally Bioavailable Enhancer of Zeste Homolog 2 (EZH2) Inhibitors Using Ligand and Property-Based Design Strategies: Identification of Development Candidate ( R )-5,8-Dichloro-7-(methoxy(oxetan-3-yl)methyl)-2-((4-methoxy-6-methyl-2-oxo-1,2-dihydropyridin-3-yl)methyl)-3,4-dihydroisoquinolin-1(2 H )-one (PF-06821497)
    Pei‐Pei Kung, Patrick Bingham, Alexei Brooun, Michael Raymond Collins, Ya‐Li Deng, Dac M. Dinh, Connie Fan, K.S. Gajiwala, Rita Grantner, Hovhannes J. Gukasyan et al. · 2017 · Journal of Medicinal Chemistry
70. Oxygen-dependent proteolysis regulates the stability of angiosperm polycomb repressive complex 2 subunit VERNALIZATION 2
    Daniel J. Gibbs, Hannah M. Tedds, Anne‐Marie Labandera, Mark Bailey, Mark D. White, Sjon Hartman, Colleen Sprigg, Sophie Louise Mogg, Rory Osborne, Charlene Dambire et al. · 2018 · Nature Communications
71. Global Changes in the Mammary Epigenome Are Induced by Hormonal Cues and Coordinated by Ezh2
    Bhupinder Pal, Toula Bouras, Wei Shi, François Vaillant, Julie M. Sheridan, Nai Yang Fu, Kelsey A. Breslin, Kun Jiang, Matthew E. Ritchie, Matthew D. Young et al. · 2013 · Cell Reports
72. The Antisense Transcript SMN-AS1 Regulates SMN Expression and Is a Novel Therapeutic Target for Spinal Muscular Atrophy
    Constantin van Outryve d’Ydewalle, Daniel M. Ramos, Noah J. Pyles, Shi‐Yan Ng, Mariusz Gorz, Celeste M. Pilato, Karen Ling, Lingling Kong, Amanda J. Ward, Lee L. Rubin et al. · 2016 · Neuron
73. Activation of Neuronal Gene Expression by the JMJD3 Demethylase Is Required for Postnatal and Adult Brain Neurogenesis
    Dae Hwi Park, Sung Jun Hong, Ryan D. Salinas, Siyuan John Liu, Shawn W. Sun, Jacopo Sgualdino, Giuseppe Testa, Martin Matthew Matzuk, Naoki Iwamori, Daniel A. Lim · 2014 · Cell Reports
74. Polycomb Repressive Complex 2 and H3K27me3 Cooperate with H3K9 Methylation To Maintain Heterochromatin Protein 1α at Chromatin
    Joanna Boros, Nausica Arnoult, Vincent Stroobant, Jean‐François Collet, Anabelle Decottignies · 2014 · Molecular and Cellular Biology
75. Transcriptional Regulation of Arabidopsis LEAFY COTYLEDON2 Involves RLE, a cis-Element That Regulates Trimethylation of Histone H3 at Lysine-27
    Nathalie Berger, Bertrand Dubreucq, François Roudier, Christian Dubos, Loı̈c Lepiniec · 2011 · The Plant Cell
76. MALAT1 long ncRNA promotes gastric cancer metastasis by suppressing PCDH10
    Ying Qi, Hong Ooi, Jun Fa Wu, Jian Chen, Xiaoli Zhang, Sheng Hui Tan, Qing Yu, Yuanyuan Li, Yani Kang, Hua Li et al. · 2016 · Oncotarget
77. Allosteric Activation Dictates PRC2 Activity Independent of Its Recruitment to Chromatin
    Chul‐Hwan Lee, Jia-Ray Yu, Sunil Kumar, Ying Jin, Gary LeRoy, Natarajan V. Bhanu, Syuzo Kaneko, Benjamin A. Garcia, Andrew D. Hamilton, Danny Reinberg · 2018 · Molecular Cell
78. EZH2 couples pancreatic regeneration to neoplastic progression.
    Jon Mallen-St Clair, Rengin G. Soydaner-Azeloglu, K. Lee, Laura J. Taylor, A. Livanos, Y. Pylayeva-Gupta, G. Miller, R. Margueron, D. Reinberg, D. Bar-Sagi · 2012 · Genes & Development
79. Genetic and epigenetic loss of microRNA-31 leads to feed-forward expression of EZH2 in melanoma
    Irfan Ahmed Asangani, Paul W. Harms, Lois M. Dodson, Mithil B. Pandhi, Lakshmi Priya Kunju, Christopher A. Maher, Douglas Randall Fullen, Timothy M. Johnson, Thomas J. Giordano, Nallasivam Palanisamy et al. · 2012 · Oncotarget
80. Selective Inhibitors of Protein Methyltransferases
    H. Ümit Kanıskan, Kyle D. Konze, Jian Jun Jin · 2014 · Journal of Medicinal Chemistry
81. The Molecular Regulation of Ethylene in Fruit Ripening
    Yudong Liu, Mingfeng Tang, Mingchun Liu, Deding Su, Jing Chen, Yushuo Gao, Mondher Bouzayen, Zhengguo Li · 2020 · Small Methods
82. Identification of a novel, recurrent MBTD1‐CXorf67 fusion in low‐grade endometrial stromal sarcoma
    Barbara Dewaele, Joanna Przybył, Anna Quattrone, Julio Finalet Ferreiro, Vanessa Vanspauwen, Ellen Geerdens, Valentina Gianfelici, Zeynep Kalender, Agnieszka Woźniak, Philippe Moerman et al. · 2013 · International Journal of Cancer
83. An integrative analysis of post-translational histone modifications in the marine diatom Phaeodactylum tricornutum
    Alaguraj Veluchamy, Achal Rastogi, Xin Lin, Bérangère Lombard, Omer Murik, Yann Thomas, Florent Dingli, Máximo Rivarola, Sandra H. Ott, Xinyue Liu et al. · 2015 · Genome biology
84. Mutations in SETD2 cause a novel overgrowth condition
    Armelle Luscan, Ingrid Laurendeau, Valérie Malan, Christine Francannet, Sylvie Odent, Fabienne Giuliano, Didier Lacombe, Renaud L. Touraine, Michel Vidaud, Éric Pasmant et al. · 2014 · Journal of Medical Genetics
85. Long noncoding RNAs: lincs between human health and disease
    Zhi Hao Kwok, Yvonne Tay · 2017 · Biochemical Society Transactions
86. Molecular Pathogenesis and Progression of Prostate Cancer
    Randy S. Schrecengost, Karen E. Knudsen · 2013 · Seminars in Oncology
87. The three-dimensional genome: regulating gene expression during pluripotency and development
    Guillaume Andrey, Stefan Mundlos · 2017 · Development
88. Long noncoding RNA SYISL regulates myogenesis by interacting with polycomb repressive complex 2
    Jianjun Jin, Wei Lv, Pan Xia, Zai Yan Xu, An Dai Zheng, Xiao‐Jing Wang, Shan Shan Wang, Rui Zeng, Hong Mei Luo, Guoliang Li et al. · 2018 · Proceedings of the National Academy of Sciences
89. PBRM1 and BAP1 as Novel Targets for Renal Cell Carcinoma
    James Brugarolas · 2013 · The Cancer Journal
90. Epigenetic control of gene regulation during development and disease: A view from the retina
    Ximena Corso‐Díaz, Catherine Jaeger, Vijender Chaitankar, Anand Swaroop · 2018 · Progress in Retinal and Eye Research
91. Advances in epigenetic therapeutics with focus on solid tumors
    Ning Yi Jin, Tiffany L. George, Gregory A. Otterson, Claire F. Verschraegen, Haitao Wen, David Paul Carbone, James Gordon Herman, Erin Marie Bertino, Kai He · 2021 · Clinical Epigenetics
92. The Arabidopsis SWI2/SNF2 Chromatin Remodeler BRAHMA Regulates Polycomb Function during Vegetative Development and Directly Activates the Flowering Repressor Gene SVP
    Chenlong Li, Chen Chen, Lei Gao, Songguang Yang, Vi Nguyen, Xuejiang Shi, Katherine A. Siminovitch, Susanne E. Kohalmi, Shangzhi Huang, Keqiang Wu et al. · 2015 · PLoS Genetics
93. Mechanisms and Disease Associations of Haplotype-Dependent Allele-Specific DNA Methylation
    Catherine Do, Charles F. Lang, J. P. Lin, Huferesh K. Darbary, Izabela Krupska, Aulona Gaba, Lynn Petukhova, Jean‐Paul Vonsattel, MARY PAT GALLAGHER, Robin Goland et al. · 2016 · The American Journal of Human Genetics
94. Oncogenic Deregulation of EZH2 as an Opportunity for Targeted Therapy in Lung Cancer
    Haikuo Zhang, Jun Qi, Jaime M. Reyes, Lewyn Li, Prakash K. Rao, Fugen Li, Charles Y. Lin, Jennifer A. Perry, Matthew A. Lawlor, Alexander Joel Federation et al. · 2016 · Cancer Discovery
95. Multiple Histone Lysine Methyltransferases Are Required for the Establishment and Maintenance of HIV-1 Latency
    Kien Nguyen, Biswajit Das, Curtis N. Dobrowolski, Jonathan Karn · 2017 · mBio
96. Ezh2 phosphorylation state determines its capacity to maintain CD8+ T memory precursors for antitumor immunity
    Shan He, Yongnian Liu, Lijun Meng, Hongxing Sun, Ying Wang, Yun Ji, Janaki Purushe, Pan Chen, Changhong Li, Jozef Madžo et al. · 2017 · Nature Communications
97. Epigenomic analysis of gastrulation identifies a unique chromatin state for primed pluripotency
    Yunlong Xiang, Yu Zhang, Qianhua Xu, Chen Zhou, Bofeng Liu, Zhenhai Du, Ke Zhang, Bingjie Zhang, Xiaoxiao Wang, Srimonta Gayen et al. · 2019 · Nature Genetics
98. The Histone Demethylase Jarid1b Ensures Faithful Mouse Development by Protecting Developmental Genes from Aberrant H3K4me3
    Mareike Albert, Sandra U. Schmitz, Susanne M. Kooistra, Martina Malatesta, Cristina Morales, Jens C. Rekling, Jens Vilstrup Johansen, Iratxe Abarrategui, Kristian Helin · 2013 · PLoS Genetics
99. Paternal heterochromatin formation in human embryos is H3K9/HP1 directed and primed by sperm-derived histone modifications
    Christine van de Werken, Godfried W. van der Heijden, Cindy Eleveld, Miriam Teeuwssen, Mareike Albert, Willy M. Baarends, Joop S.E. Laven, Antoine H.F.M. Peters, Esther B. Baart · 2014 · Nature Communications
100. SET domain proteins in plant development
     Tage Thorstensen, Paul E. Grini, Reidunn B. Aalen · 2011 · Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms