TET1 and hydroxymethylcytosine in transcription and DNA methylation fidelity

Conversion of 5-Methylcytosine to 5-Hydroxymethylcytosine in Mammalian DNA by MLL Partner TET1

Tahiliani, M., Koh, K. P., Shen, Y., Pastor, W. A., Bandukwala, H., Brudno, Y., Agarwal, S., Iyer, L. M., Liu, D. R., Aravind, L., et al. (2009) · Science · doi:10.1126/science.1170116 · Cited by 5,836

Genome-wide maps of chromatin state in pluripotent and lineage-committed cells

Mikkelsen, T. S., Ku, M., Jaffe, D. B., Issac, B., Lieberman, E., Giannoukos, G., Alvarez, P., Brockman, W., Kim, T.-K., Koche, R. P., et al. (2007) · Nature · doi:10.1038/nature06008 · Cited by 4,129

DNA methylation landscapes: Provocative insights from epigenomics

Suzuki, M. M., & Bird, A. (2008) · Nature Reviews Genetics · doi:10.1038/nrg2341 · Cited by 3,039

The Nuclear DNA Base 5-Hydroxymethylcytosine Is Present in Purkinje Neurons and the Brain

Kriaucionis, S., & Heintz, N. (2009) · Science · doi:10.1126/science.1169786 · Cited by 2,700

Role of Tet proteins in 5mC to 5hmC conversion, ES-cell self-renewal and inner cell mass specification

Ito, S., D’Alessio, A. C., Taranova, O., Hong, K., Sowers, L. C., & Zhang, Y. (2010) · Nature · doi:10.1038/nature09303 · Cited by 2,628

Genome-scale DNA methylation maps of pluripotent and differentiated cells

Meissner, A., Mikkelsen, T. S., Gu, H., Wernig, M., Hanna, J., Sivachenko, A., Zhang, X., Bernstein, B. E., Nusbaum, C., Jaffe, D. B., et al. (2008) · Nature · doi:10.1038/nature07107 · Cited by 2,536

Linking DNA methylation and histone modification: patterns and paradigms

Cedar, H., & Bergman, Y. (2009) · Nature Reviews Genetics · doi:10.1038/nrg2540 · Cited by 2,267

Chromosome-wide and promoter-specific analyses identify sites of differential DNA methylation in normal and transformed human cells

Weber, M., Davies, J. J., Wittig, D., Oakeley, E. J., Haase, M., Lam, W. L., & Schübeler, D. (2005) · Nature Genetics · doi:10.1038/ng1598 · Cited by 1,785

Mutation in TET2 in Myeloid Cancers

Delhommeau, F., Dupont, S., Valle, V. D., James, C., Trannoy, S., Massé, A., Kosmider, O., Le Couedic, J.-P., Robert, F., Alberdi, A., et al. (2009) · New England Journal of Medicine · doi:10.1056/nejmoa0810069 · Cited by 1,776

Conserved role of intragenic DNA methylation in regulating alternative promoters

Maunakea, A. K., Nagarajan, R. P., Bilenky, M., Ballinger, T. J., D’Souza, C., Fouse, S. D., Johnson, B. E., Hong, C., Nielsen, C., Zhao, Y., et al. (2010) · Nature · doi:10.1038/nature09165 · Cited by 1,743

Dynamic CpG methylation delineates subregions within super-enhancers selectively decommissioned at the exit from naive pluripotency

Bell, E., Curry, E. W., Megchelenbrink, W., Jouneau, L., Brochard, V., Tomaz, R. A., Mau, K. H. T., Atlasi, Y., de Souza, R. A., Marks, H., et al. (2020) · Nature Communications · doi:10.1038/s41467-020-14916-7 · Cited by 50

TET enzymatic oxidation of 5-methylcytosine, 5-hydroxymethylcytosine and 5-formylcytosine

Cadet, J., & Wagner, J. R. (2013) · Mutation Research/Genetic Toxicology and Environmental Mutagenesis · doi:10.1016/j.mrgentox.2013.09.001 · Cited by 53

MYC deregulates TET1 and TET2 expression to control global DNA (hydroxy)methylation and gene expression to maintain a neoplastic phenotype in T-ALL

Poole, C. J., Lodh, A., Choi, J.-H., & van Riggelen, J. (2019) · Epigenetics & Chromatin · doi:10.1186/s13072-019-0278-5 · Cited by 52

TET2 is a component of the estrogen receptor complex and controls 5mC to 5hmC conversion at estrogen receptor cis-regulatory regions

Broome, R., Chernukhin, I. V., Jamieson, S., Kishore, K., Papachristou, E. K., Mao, S.-Q., Tejedo, C. G., Mahtey, A., Theodorou, V., Groen, A. J., et al. (2021) · Cell Reports · doi:10.1016/j.celrep.2021.108776 · Cited by 50

The Impact of Nutrition on Differential Methylated Regions of the Genome

Parle‐McDermott, A., & Ozaki, M. (2011) · Advances in Nutrition · doi:10.3945/an.111.001008 · Cited by 50

An epigenetic switch repressing Tet1 in gonadotropes activates the reproductive axis

Yosefzon, Y., David, C., Tsukerman, A., Pnueli, L., Qiao, S., Boehm, U., & Melamed, P. (2017) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1704393114 · Cited by 51

Association of Bisphenol A Exposure with LINE-1 Hydroxymethylation in Human Semen

Tian, Y., Zhou, X., Miao, M., Li, D., Wang, Z., Li, R., Liang, H., & Yuan, W. (2018) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph15081770 · Cited by 48

Tet2 Inactivation Enhances the Antitumor Activity of Tumor-Infiltrating Lymphocytes

Lee, M., Li, J., Li, J., Fang, S., Zhang, J., Vo, A. T. T., Han, W., Zeng, H., Isgandarova, S., Martinez-Moczygemba, M., et al. (2021) · Cancer Research · doi:10.1158/0008-5472.can-20-3213 · Cited by 47

5-Hydroxymethylcytosine: the many faces of the sixth base of mammalian DNA

Kriukienė, E., Tomkuvienė, M., & Klimašauskas, S. (2024) · Chemical Society Reviews · doi:10.1039/d3cs00858d · Cited by 50

The Combination of Tet1 with Oct4 Generates High-Quality Mouse-Induced Pluripotent Stem Cells

Chen, J., Gao, Y., Huang, H., Xu, K., Chen, X., Jiang, Y., Li, H., Gao, S., Tao, Y., Wang, H., et al. (2014) · Stem Cells · doi:10.1002/stem.1879 · Cited by 48

TET1 is controlled by pluripotency-associated factors in ESCs and downmodulated by PRC2 in differentiated cells and tissues

Neri, F., Incarnato, D., Křepelová, A., Dettori, D., Rapelli, S., Maldotti, M., Parlato, C., Anselmi, F., Galvagni, F., & Oliviero, S. (2015) · Nucleic Acids Research · doi:10.1093/nar/gkv392 · Cited by 51

The emerging role of tumor-suppressive microRNA-218 in targeting glioblastoma stemness

Gao, X., & Jin, W. (2014) · Cancer Letters · doi:10.1016/j.canlet.2014.07.011 · Cited by 49

Polycomb- and REST-associated histone deacetylases are independent pathways toward a mature neuronal phenotype

McGann, J. C., Oyer, J. A., Garg†, S. K., Yao, H., Liu, J., Feng, X., Liao, L., Yates, J. R., & Mandel, G. (2014) · eLife · doi:10.7554/elife.04235 · Cited by 47

Same agent, different messages: insight into transcriptional regulation by SIN3 isoforms

Chaubal, A., & Pile, L. A. (2018) · Epigenetics & Chromatin · doi:10.1186/s13072-018-0188-y · Cited by 48

Glioblastoma Recurrence and the Role of O6-Methylguanine–DNA Methyltransferase Promoter Methylation

Storey, K. M., Leder, K., Hawkins-Daarud, A. J., Swanson, K. R., Ahmed, A. U., Rockne, R. C., & Foo, J. (2019) · JCO Clinical Cancer Informatics · doi:10.1200/cci.18.00062 · Cited by 50

The failure of DAC to induce OCT2 expression and its remission by hemoglobin-based nanocarriers under hypoxia in renal cell carcinoma

Lü, C., Wang, Z., Xu, Q., Liu, Y., Chen, L., Guo, S., Wang, H., Zeng, S., Liu, J., Zeng, S., et al. (2020) · Theranostics · doi:10.7150/thno.39944 · Cited by 48

The placenta: epigenetic insights into trophoblast developmental models of a generation-bridging organ with long-lasting impact on lifelong health

Hemberger, M., & Dean, W. (2023) · Physiological Reviews · doi:10.1152/physrev.00001.2023 · Cited by 48

Epigenetic reprogramming: is deamination key to active DNA demethylation?

Teperek, M., Pasque, V., Gentsch, G. E., & Ferguson‐Smith, A. C. (2011) · Reproduction · doi:10.1530/rep-11-0148 · Cited by 47

Chromosome-wide regulation of euchromatin-specific 5mC to 5hmC conversion in mouse ES cells and female human somatic cells

Kubiura‐Ichimaru, M., Okano, M., Kimurâ, H., Kawamura, F., & Tada, M. (2012) · Chromosome Research · doi:10.1007/s10577-012-9317-9 · Cited by 47

TET proteins: on the frenetic hunt for new cytosine modifications

Delatte, B., & Fuks, F. (2013) · Briefings in Functional Genomics · doi:10.1093/bfgp/elt010 · Cited by 51

Structure and Function of TET Enzymes

Yin, X., & Xu, Y. (2016) · Advances in experimental medicine and biology · doi:10.1007/978-3-319-43624-1_12 · Cited by 48

Protein Interactions at Oxidized 5-Methylcytosine Bases

Pfeifer, G. P., Szabó, P. E., & Song, J. (2019) · Journal of Molecular Biology · doi:10.1016/j.jmb.2019.07.039 · Cited by 49

Tet1 Deficiency Leads to Premature Reproductive Aging by Reducing Spermatogonia Stem Cells and Germ Cell Differentiation

Huang, G., Liu, L., Wang, H., Gou, M., Gong, P., Tian, C., Deng, W., Yang, J., Zhou, T.-T., Xu, G.-L., et al. (2020) · iScience · doi:10.1016/j.isci.2020.100908 · Cited by 48

Prognostic Value of Neoantigen Load in Immune Checkpoint Inhibitor Therapy for Cancer

Zou, X.-L., Li, X., Ke, H., Zhang, G., Tang, Q., Yuan, J., Zhou, C.-J., Zhang, J., Zhang, R., & Chen, W.-Y. (2021) · Frontiers in Immunology · doi:10.3389/fimmu.2021.689076 · Cited by 48

Epigenetic Factors in Eutopic Endometrium in Women with Endometriosis and Infertility

Adamczyk, M., Wender-Ożegowska, E., & Kędzia, M. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms23073804 · Cited by 51

Hydroxymethylation and its potential implication in DNA repair system: A review and future perspectives

Shukla, A., Sehgal, M., & Singh, T. R. (2015) · Gene · doi:10.1016/j.gene.2015.03.075 · Cited by 46

Epigenetic regulation of hematopoiesis

Sashida, G., & Iwama, A. (2012) · International Journal of Hematology · doi:10.1007/s12185-012-1183-x · Cited by 47

Spectroscopic quantification of 5-hydroxymethylcytosine in genomic DNA using boric acid-functionalized nano-microsphere fluorescent probes

Chen, H., Wei, J., Pan, J.-X., Zhang, W. E., Dang, F., Zhang, Z., & Zhang, J. (2016) · Biosensors and Bioelectronics · doi:10.1016/j.bios.2016.12.039 · Cited by 46

Diesel exhaust and house dust mite allergen lead to common changes in the airway methylome and hydroxymethylome

Zhang, X., Chen, X., Weirauch, M. T., Zhang, X., Burleson, J., Brandt, E. B., & Ji, H. (2018) · Current Zoology · doi:10.1093/eep/dvy020 · Cited by 47

Alpha-ketoglutarate affects murine embryo development through metabolic and epigenetic modulations

Zhang, Z., He, C., Zhang, L., Zhu, T., Lv, D., Li, G., Song, Y., Wang, J., Wu, H., Ji, P., et al. (2019) · Reproduction · doi:10.1530/rep-19-0018 · Cited by 47

DNA methylation reprogramming in cancer: Does it act by re‐configuring the binding landscape of Polycomb repressive complexes?

Reddington, J. P., Sproul, D., & Meehan, R. R. (2013) · BioEssays · doi:10.1002/bies.201300130 · Cited by 45

Manipulation of prostate cancer metastasis by locus-specific modification of the CRMP4 promoter region using chimeric TALE DNA methyltransferase and demethylase

Li, K., Pang, J., Cheng, H., Liu, W., Di, J., Xiao, H.-J., Luo, Y., Zhang, H., Huang, W., Chen, M., et al. (2015) · Oncotarget · doi:10.18632/oncotarget.3192 · Cited by 46

A modular open platform for systematic functional studies under physiological conditions

Mulholland, C. B., Smets, M., Schmidtmann, E., Leidescher, S., Markaki, Y., Hofweber, M., Qin, W., Manzo, M., Kremmer, E., Thanisch, K., et al. (2015) · Nucleic Acids Research · doi:10.1093/nar/gkv550 · Cited by 47

Integrating DNA methylation dynamics into a framework for understanding epigenetic codes

Szulwach, K. E., & Jin, P. (2013) · BioEssays · doi:10.1002/bies.201300090 · Cited by 50

Role of epigenetic mechanisms in epithelial-to-mesenchymal transition of breast cancer cells

Nickel, A., & Stadler, S. C. (2014) · Translational research · doi:10.1016/j.trsl.2014.04.001 · Cited by 44

Tet1 Deficiency Leads to Premature Ovarian Failure

Liu, L., Wang, H., Xu, G. L., & Liu, L. (2021) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2021.644135 · Cited by 49

Epigenetic Alterations in Acute Kidney Injury

Bomsztyk, K., & Denisenko, O. N. (2013) · Seminars in Nephrology · doi:10.1016/j.semnephrol.2013.05.005 · Cited by 44

Emerging roles of mitochondrial functions and epigenetic changes in the modulation of stem cell fate

Zhang, C., Meng, Y., & Han, J. (2024) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-023-05070-6 · Cited by 51

C/EBPβ (CEBPB) protein binding to the C/EBP|CRE DNA 8-mer TTGC|GTCA is inhibited by 5hmC and enhanced by 5mC, 5fC, and 5caC in the CG dinucleotide

Khund-Sayeed, S., Zhao, J., Sathyanarayana, B. K., Golla, J. P., & Vinson, C. (2015) · Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms · doi:10.1016/j.bbagrm.2015.03.002 · Cited by 42

Polycomb Binding Precedes Early-Life Stress Responsive DNA Methylation at the Avp Enhancer

Murgatroyd, C., & Spengler, D. (2014) · PLoS ONE · doi:10.1371/journal.pone.0090277 · Cited by 45

The emerging insights into catalytic or non-catalytic roles of TET proteins in tumors and neural development

Lian, H., Li, W., & Jin, W. (2016) · Oncotarget · doi:10.18632/oncotarget.11412 · Cited by 45

Naphthalimide derivatives as multifunctional molecules for detecting 5-formylpyrimidine by both PAGE analysis and dot-blot assays

Wang, Y., Liu, C., Yang, W., Zou, G., Zhang, X., Wu, F., Yu, S., Luo, X., & Zhou, X. (2018) · Chemical Communications · doi:10.1039/c7cc08715b · Cited by 45

Assessment of DNA Epigenetic Modifications

Yuan, B. (2019) · Chemical Research in Toxicology · doi:10.1021/acs.chemrestox.9b00372 · Cited by 46

TET1 regulates gene expression and repression of endogenous retroviruses independent of DNA demethylation

Stolz, P., Mantero, A. S., Tvardovskiy, A., Ugur, E., Wange, L. E., Mulholland, C. B., Cheng, Y., Wierer, M., Enard, W., Schneider, R., et al. (2022) · Nucleic Acids Research · doi:10.1093/nar/gkac642 · Cited by 43

The Intrinsic and Extrinsic Effects of Tet Proteins During Gastrulation

Cheng, S., Mittnenzweig, M., Mayshar, Y., Lifshitz, A., Dunjić, M., Rais, Y., Ben-Yair, R., Gehrs, S., Chomsky, E., Mukamel, Z., et al. (2021) · Cell · doi:10.1016/j.cell.2022.06.049 · Cited by 43

Impaired DNA demethylation of C/EBP sites causes premature agingPreprint

Schäfer, A., Mekker, B., Mallick, M., Vastolo, V., Karaulanov, E., Sebastian, D., von der Lippen, C., Epe, B., Downes, D. J., Scholz, C., et al. (2018) · Genes & Development · doi:10.1101/gad.311969.118 · Cited by 42

Decoding the role of TET family dioxygenases in lineage specification

Wu, X., Li, G., & Xie, R. (2018) · Epigenetics & Chromatin · doi:10.1186/s13072-018-0228-7 · Cited by 43

The Genome- and System-Wide Response of DNA Methylation to Early Life Adversity and its Implication on Mental Health

Moshe Szyf, A. (2013) · The Canadian Journal of Psychiatry · doi:10.1177/070674371305801208 · Cited by 43

DNA–Methylome Analysis of Mouse Intestinal Adenoma Identifies a Tumour-Specific Signature That Is Partly Conserved in Human Colon Cancer

Grimm, C., Chávez, L., Vilardell, M., Farrall, A. L., Tierling, S., Böhm, J. W., Grote, P., Lienhard, M., Dietrich, J., Timmermann, B., et al. (2013) · PLoS Genetics · doi:10.1371/journal.pgen.1003250 · Cited by 43

Establishment of epigenetic patterns in development

Leeb, M., & Wutz, A. (2012) · Chromosoma · doi:10.1007/s00412-012-0365-x · Cited by 46

Intrinsic and Extrinsic Connections of Tet3 Dioxygenase with CXXC Zinc Finger Modules

Liu, N., Wang, M., Deng, W., Schmidt, C. S., Qin, W., Leonhardt, H., & Spada, F. (2013) · PLoS ONE · doi:10.1371/journal.pone.0062755 · Cited by 45

O-GlcNAcylation and chromatin remodeling in mammals: an up-to-date overview

Leturcq, M., Lefebvre, T., & Vercoutter‐Edouart, A. (2017) · Biochemical Society Transactions · doi:10.1042/bst20160388 · Cited by 43

Individual retrotransposon integrants are differentially controlled by KZFP/KAP1-dependent histone methylation, DNA methylation and TET-mediated hydroxymethylation in naïve embryonic stem cells

Coluccio, A., Ecco, G., Duc, J., Offner, S., Turelli, P., & Trono, D. (2018) · Epigenetics & Chromatin · doi:10.1186/s13072-018-0177-1 · Cited by 42

Evolutionary expansion of DNA hypomethylation in the mammalian germline genomePreprint

Qu, J., Hodges, E. C., Molaro, A., Gagneux, P., Dean, M. D., Hannon, G. J., & Smith, A. D. (2017) · Genome Research · doi:10.1101/gr.225896.117 · Cited by 46

TET2 Deficiency Inhibits Mesoderm and Hematopoietic Differentiation in Human Embryonic Stem Cells

Langlois, T., Monte-Mór, B. D. C. R., Lenglet, G., Droin, N. M., Marty, C., Couedic, J. P. L., Almire, C., Auger, N., Mercher, T., Delhommeau, F., et al. (2014) · Stem Cells · doi:10.1002/stem.1718 · Cited by 46

Intracellular Detection of Cytosine Incorporation in Genomic DNA by Using 5‐Ethynyl‐2′‐Deoxycytidine

Guan, L., van der Heijden, G. W., Bortvin, A. L., & Greenberg, M. M. (2011) · ChemBioChem · doi:10.1002/cbic.201100353 · Cited by 43

The Methylcytosine Dioxygenase Ten-Eleven Translocase-2 (tet2) Enables Elevated GnRH Gene Expression and Maintenance of Male Reproductive Function

Kurian, J. R., Louis, S., Keen, K. L., Wolfe, A., Terasawa, E., & Levine, J. E. (2016) · Endocrinology · doi:10.1210/en.2016-1087 · Cited by 42

Hypoxia-induced TET1 facilitates trophoblast cell migration and invasion through HIF1α signaling pathway

Zhu, J., Wang, K., Li, T., Chen, J., Xie, D., Chang, X., Yao, J., Wu, J., Zhou, Q., Jia, Y., et al. (2017) · Scientific Reports · doi:10.1038/s41598-017-07560-7 · Cited by 42

Tet-Mediated DNA Demethylation Is Required for SWI/SNF-Dependent Chromatin Remodeling and Histone-Modifying Activities That Trigger Expression of the Sp7 Osteoblast Master Gene during Mesenchymal Lineage Commitment

Sepúlveda, H., Villagra, A., & Montecino, M. A. (2017) · Molecular and Cellular Biology · doi:10.1128/mcb.00177-17 · Cited by 44

Gene specific-loci quantitative and single-base resolution analysis of 5-formylcytosine by compound-mediated polymerase chain reaction

Wang, Y., Liu, C., Zhang, X., Yang, W., Wu, F., Zou, G., Weng, X., & Zhou, X. (2018) · Chemical Science · doi:10.1039/c8sc00493e · Cited by 42

Single-cell bisulfite-free 5mC and 5hmC sequencing with high sensitivity and scalability

Cao, Y., Bai, Y., Yuan, T., Song, L., Fan, Y., Ren, L., Song, W., Peng, J., An, R., Gu, Q., et al. (2023) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2310367120 · Cited by 45

Environmental Alterations of Epigenetics Prior to the Birth

Lo, C., & Zhou, F. (2014) · International review of neurobiology · doi:10.1016/b978-0-12-801311-3.00001-9 · Cited by 44

Epigenomic Co-localization and Co-evolution Reveal a Key Role for 5hmC as a Communication Hub in the Chromatin Network of ESCs

Juan, D., Perner, J., Pau, E. C. D. S., Marsili, S., Ochoa, D., Chung, H., Vingron, M., Rico, D., & Valencia, A. (2016) · Cell Reports · doi:10.1016/j.celrep.2016.01.008 · Cited by 41

Transcriptional and epigenetic mechanisms of cellular reprogramming to induced pluripotency

van den Hurk, M., Kenis, G., Bardy, C., van den Hove, D., Gage, F. H., Steinbusch, H. W. M., & Rutten, B. P. F. (2016) · Epigenomics · doi:10.2217/epi-2016-0032 · Cited by 44

TET1 contributes to allergic airway inflammation and regulates interferon and aryl hydrocarbon receptor signaling pathways in bronchial epithelial cells

Burleson, J., Siniard, D. J., Yadagiri, V. K., Chen, X., Weirauch, M. T., Ruff, B. P., Brandt, E. B., Hershey, G. K. K., & Ji, H. (2019) · Scientific Reports · doi:10.1038/s41598-019-43767-6 · Cited by 43

Pioneer transcription factors are associated with the modulation of DNA methylation patterns across cancers

Lemma, R. B., Fleischer, T., Martinsen, E., Ledsaak, M., Kristensen, V. N., Eskeland, R., Gabrielsen, O. S., & Mathelier, A. (2022) · Epigenetics & Chromatin · doi:10.1186/s13072-022-00444-9 · Cited by 47

Enzymatic Analysis of Tet Proteins: Key Enzymes in the Metabolism of DNA Methylation

Shen, L., & Zhang, Y. (2012) · Methods in enzymology on CD-ROM/Methods in enzymology · doi:10.1016/b978-0-12-391940-3.00005-6 · Cited by 40

On the potential role of active DNA demethylation in establishing epigenetic states associated with neural plasticity and memory

Li, X., Wei, W., Ratnu, V. S., & Bredy, T. W. (2013) · Neurobiology of Learning and Memory · doi:10.1016/j.nlm.2013.06.009 · Cited by 39

Ischemia-Induced DNA Hypermethylation during Kidney Transplant Predicts Chronic Allograft Injury

Heylen, L., Thienpont, B., Naesens, M., Busschaert, P., Depreeuw, J., Smeets, D., Jochmans, I., Monbaliu, D. R. L., Pirenne, J., Lerut, E., et al. (2018) · Journal of the American Society of Nephrology · doi:10.1681/asn.2017091027 · Cited by 40

Mammalian Germ Cell Development: From Mechanism to In Vitro Reconstitution

Saitou, M. (2021) · Stem Cell Reports · doi:10.1016/j.stemcr.2021.01.008 · Cited by 42

DNMT3L interacts with transcription factors to target DNMT3L/DNMT3B to specific DNA sequences: Role of the DNMT3L/DNMT3B/p65-NFκB complex in the (de-)methylation of TRAF1

Pacaud, R., Séry, Q., Oliver, L., Vallette, F. M., Tost, J., & Cartron, P. (2014) · Biochimie · doi:10.1016/j.biochi.2014.05.005 · Cited by 39

Epigenetic Upregulation of Large-Conductance Ca 2+ -Activated K + Channel Expression in Uterine Vascular Adaptation to Pregnancy

Chen, M., Dasgupta, C., Xiong, F., & Zhang, L. (2014) · Hypertension · doi:10.1161/hypertensionaha.114.03407 · Cited by 39

Regulation and function of mammalian DNA methylation patterns: a genomic perspective

Wu, H., Tao, J., & Sun, Y. E. (2012) · Briefings in Functional Genomics · doi:10.1093/bfgp/els011 · Cited by 40

TET proteins in cancer: Current ‘state of the art’

Rawłuszko-Wieczorek, A. A., Siera, A., & Jagodziński, P. P. (2015) · Critical Reviews in Oncology/Hematology · doi:10.1016/j.critrevonc.2015.07.008 · Cited by 40

Epigenetic Regulation

Minárovits, J., Bánáti, F., Szenthe, K., & Niller, H. H. (2015) · Advances in experimental medicine and biology · doi:10.1007/978-3-319-24738-0_1 · Cited by 42

Genome-wide mapping of 5-hydroxymethylcytosine in three rice cultivars reveals its preferential localization in transcriptionally silent transposable element genes

Wang, X., Song, S., Yong-sheng, W., Li, Y., Chen, T., Huang, Z., Liu, S., Dunwell, T. L., Pfeifer, G. P., Dunwell, J. M., et al. (2015) · Journal of Experimental Botany · doi:10.1093/jxb/erv372 · Cited by 39

Excision of 5-hydroxymethylcytosine by DEMETER family DNA glycosylases

Jang, H., Shin, H., Eichman, B. F., & Huh, J. H. (2014) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2014.03.060 · Cited by 39

Dnmt3a Regulates Global Gene Expression in Olfactory Sensory Neurons and Enables Odorant-Induced Transcription

Colquitt, B. M., Markenscoff-Papadimitriou, E., Duffié, R., & Lomvardas, S. (2014) · Neuron · doi:10.1016/j.neuron.2014.07.013 · Cited by 38

5-Hydroxymethylcytosine (5hmC), or How to Identify Your Favorite Cell

Ecsedi, S., Rodríguez‐Aguilera, J. R., & Hernández‐Vargas, H. (2018) · Epigenomes · doi:10.3390/epigenomes2010003 · Cited by 40

Establishment of methylation patterns in ES cells

Sabag, O., Zamir, A., Keshet, I., Hecht, M., Ludwig, G., Tabib, A., Moss, J., & Cedar, H. (2013) · Nature Structural & Molecular Biology · doi:10.1038/nsmb.2734 · Cited by 37

Linking metabolism and epigenetic regulation in development of hepatocellular carcinoma

Puszyk, W. M., Trinh, T. L., Chapple, S. J., & Liu, C. (2013) · Laboratory Investigation · doi:10.1038/labinvest.2013.94 · Cited by 38

5-hydroxymethylcytosine represses the activity of enhancers in embryonic stem cells: a new epigenetic signature for gene regulation

Choi, I., Kim, R., Lim, H., Kaestner, K. H., & Won, K. (2014) · BMC Genomics · doi:10.1186/1471-2164-15-670 · Cited by 39

Epigenetic profiling joins personalized cancer medicine

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