Chromosomal instability drives metastasis through a cytosolic DNA response

Bakhoum, Samuel F., Ngo, Bryan, Laughney, Ashley M., Cavallo, Julie-Ann, Murphy, Charles J., Ly, Peter, Shah, Pragya, Sriram, Roshan K., Watkins, Thomas B. K., Taunk, Neil K., Duran, Mercedes, Pauli, Chantal, Shaw, Christine, Chadalavada, Kalyani, Rajasekhar, Vinagolu K., Genovese, Giulio, Venkatesan, Subramanian, Birkbak, Nicolai J., McGranahan, Nicholas, Lundquist, Mark, LaPlant, Quincey, Healey, John H., Elemento, Olivier, Chung, Christine H., Lee, Nancy Y., Imielenski, Marcin, Nanjangud, Gouri, Pe’er, Dana, Cleveland, Don W., Powell, Simon N., Lammerding, Jan, Swanton, Charles, Cantley, Lewis C.·2018·Nature
DOI 10.1038/nature25432

Cited by (1,551)

Items 201–300 of 1,551

  1. Mitotic clustering of pulverized chromosomes from micronuclei
    Yu-Fen Lin, Qing Hu, Alice Mazzagatti, Jose Espejo Valle-Inclán, Elizabeth G. Maurais, Rashmi Dahiya, Alison Guyer, Jacob T. Sanders, Justin L. Engel, Giaochau Nguyen et al. · 2023 · Nature
  2. Premature mitotic entry induced by ATR inhibition potentiates olaparib inhibition-mediated genomic instability, inflammatory signaling, and cytotoxicity in BRCA2-deficient cancer cells
    Schoonen, Pepijn M., Kok, Yannick P., Wierenga, Elles, Bakker, Bjorn, Foijer, Floris, Spierings, Diana C. J., van Vugt, Marcel A. T. M. · 2019 · Molecular Oncology
  3. Obesity and Cancer Metastasis: Molecular and Translational Perspectives
    Stephanie Annett, Gillian Moore, Tracy Robson · 2020 · Cancers
  4. Aneuploid senescent cells activate NF-κB to promote their immune clearance by NK cells
    Ruoxi W. Wang, Sonia Viganò, Uri Ben‐David, Angelika Amon, Stefano Santaguida · 2021 · EMBO Reports
  5. Homing in on genomic instability as a therapeutic target in cancer
    Craig M. Bielski, Barry S. Taylor · 2021 · Nature Communications
  6. Paclitaxel Induces Micronucleation and Activates Pro-Inflammatory cGAS–STING Signaling in Triple-Negative Breast Cancer
    Yang Hu, Baraa K. Manasrah, Stephanie M. McGregor, Robert F. Lera, Roshan X. Norman, John B. Tucker, Christina M. Scribano, Rachel E. Yan, Mouhita Humayun, Kari Braun Wisinski et al. · 2021 · Molecular Cancer Therapeutics
  7. A non-canonical, interferon-independent signaling activity of cGAMP triggers DNA damage response signaling
    Daipayan Banerjee, Kurt A. Langberg, Salar Abbas, Eric Odermatt, Praveen Yerramothu, Martin P. Volaric, Matthew A. Reidenbach, Kathleen J. Krentz, Clifford Dustin Rubinstein, David L. Brautigan et al. · 2021 · Nature Communications
  8. ESCRT-III is necessary for the integrity of the nuclear envelope in micronuclei but is aberrant at ruptured micronuclear envelopes generating damage
    Jessica Willan, Alexa J. Cleasby, Neftali Flores Rodriguez, Flavia Stefani, Cinzia Rinaldo, Alessandra Pisciottani, Emma K. Grant, Philip G. Woodman, Helen E. Bryant, Barbara Ciani · 2019 · Oncogenesis
  9. The Tubulin Code in Mitosis and Cancer
    Danilo Lopes, Hélder Maiato · 2020 · Cells
  10. Tissue fluidification promotes a cGAS–STING cytosolic DNA response in invasive breast cancer
    Emanuela Frittoli, Andrea Palamidessi, Fabio Iannelli, Federica Zanardi, Stefano Villa, Leonardo Barzaghi, Hind Abdo, Valeria Cancila, Galina V. Beznoussenko, Giulia Della Chiara et al. · 2022 · Nature Materials
  11. ENPP1 is an innate immune checkpoint of the anticancer cGAMP–STING pathway in breast cancer
    Songnan Wang, Volker Böhnert, Alby J. Joseph, Valentino Sudaryo, Gemini M. Skariah, Jason T. Swinderman, Feiqiao Brian Yu, Vishvak Subramanyam, Denise M. Wolf, Xuchao Lyu et al. · 2023 · Proceedings of the National Academy of Sciences
  12. Molecular Characteristics of Uveal Melanoma: Insights from the Cancer Genome Atlas (TCGA) Project
    Mathieu F. Bakhoum, Bita Esmaeli · 2019 · Cancers
  13. Genomic signature of Fanconi anaemia DNA repair pathway deficiency in cancer
    Andrew Webster, Mathijs Arnoud Sanders, Krupa Patel, Ralf Dietrich, Raymond J. Noonan, Francis P. Lach, Ryan R. White, Audrey M. Goldfarb, Kevin Hadi, Matthew M. Edwards et al. · 2022 · Nature
  14. cGAS-STING signaling in the tumor microenvironment
    Ziqi Liu, Dan Wang, Jiarong Zhang, Pingjuan Xiang, Zhaoyang Zeng, Wei Xiong, Lei Shi · 2023 · Cancer Letters
  15. Chromosomal instability and aneuploidy as causes of cancer drug resistance
    Devon A. Lukow, Jason M. Sheltzer · 2021 · Trends in cancer
  16. The cGAS-STING Pathway: Novel Perspectives in Liver Diseases
    Dongwei Xu, Yizhu Tian, Qiang Xia, Bibo Ke · 2021 · Frontiers in Immunology
  17. cGAS restricts colon cancer development by protecting intestinal barrier integrity
    Shuiqing Hu, Yan Fang, Xiang Chen, Tianlei Cheng, Miaoqing Zhao, Mingjian Du, Tuo Li, Minghao Li, Zhiqun Zeng, Yonglong Wei et al. · 2021 · Proceedings of the National Academy of Sciences
  18. Extensive protein dosage compensation in aneuploid human cancers
    Klaske M. Schukken, Jason M. Sheltzer · 2022 · Genome Research
  19. Risks associated with enterococci as probiotics
    Xingmin Wang, Yonghong Yang, Mark M. Huycke · 2019 · Food Research International
  20. Irradiation induces cancer lung metastasis through activation of the cGAS–STING–CCL5 pathway in mesenchymal stromal cells
    Zhiyuan Zheng, Shanfen Jia, Changshun Shao, Yufang Shi · 2020 · Cell Death and Disease
  21. Chromosome Abnormalities: New Insights into Their Clinical Significance in Cancer
    Fan Kou, Lei Wu, Xiubao Ren, Lili Yang · 2020 · Molecular Therapy — Oncolytics
  22. TGFβ signaling networks in ovarian cancer progression and plasticity
    Asha Kumari, Zainab Shonibare, Mehri Monavarian, Rebecca Christian Arend, Nam Y. Lee, Gareth J. Inman, Karthikeyan Mythreye · 2021 · Clinical & Experimental Metastasis
  23. Radiation-Induced Immunity and Toxicities: The Versatility of the cGAS-STING Pathway
    Julie Constanzo, Julien Faget, Chiara Ursino, Christophe Badie, Jean‐Pierre Pouget · 2021 · Frontiers in Immunology
  24. Metal ions and nanometallic materials in antitumor immunity: Function, application, and perspective
    Feiyang Shen, Yan Fang, Yijia Wu, Min Zhou, Jianfeng Shen, Xianqun Fan · 2023 · Journal of Nanobiotechnology
  25. Micronuclear collapse from oxidative damage
    Melody Di Bona, Yanyang Chen, Albert S. Agustinus, Alice Mazzagatti, Mercedes A. Duran Paez, Matthew Deyell, Daniel Bronder, James H. Hickling, Christy Hong, Lorenzo Scipioni et al. · 2024 · Science
  26. Cell cycle dysregulation in cancer
    Antonino Glaviano, Samarendra Kumar Singh, E. Hui Clarissa Lee, Elena Okina, Hiu Yan Lam, Daniela Carbone, E. Premkumar Reddy, Mark J. O’Connor, Andrew Koff, Garima Singh et al. · 2024 · Pharmacological Reviews
  27. Squeezing through the microcirculation: survival adaptations of circulating tumour cells to seed metastasis
    Julia Perea Paizal, Sam H. Au, Chris Bakal · 2020 · British Journal of Cancer
  28. MYC Dysregulates Mitosis, Revealing Cancer Vulnerabilities
    Julia Rohrberg, Daniel Van de Mark, Meelad Amouzgar, Joyce V. Lee, Moufida Taileb, Alexandra N. Corella, Seda Kilinc, Jeremy R. Williams, Marie‐Lena Jokisch, Roman Camarda et al. · 2020 · Cell Reports
  29. Centrosome dysfunction: a link between senescence and tumor immunity
    Qi Wu, Bei Li, Le Liu, Shengrong Sun, Si Sun · 2020 · Signal Transduction and Targeted Therapy
  30. Apoptosis – Fueling the oncogenic fire
    Camila Castillo Ferrer, Kévin Berthenet, Gabriel Ichim · 2020 · FEBS Journal
  31. Radiotherapy: An immune response modifier for immuno-oncology
    Mara De Martino, Camille Daviaud, Claire Vanpouille‐Box · 2021 · Seminars in Immunology
  32. Chromosomal copy number heterogeneity predicts survival rates across cancers
    Erik van Dijk, Tom van den Bosch, Kristiaan Lenos, Khalid El Makrini, Lisanne E. Nijman, Hendrik F HFvE Van Essen, Nico R. Lansu, Michiel Boekhout, Joris H. Hageman, Rebecca Claire Fitzgerald et al. · 2021 · Nature Communications
  33. Guidance on aneugenicity assessment
    Simon J. More, Vasileios Bampidis, Claude Bragard et al. · 2021 · EFSA Journal
  34. DNA Damage and Activation of cGAS/STING Pathway Induce Tumor Microenvironment Remodeling
    Rong Shen, Disheng Liu, Xiaoning Wang, Zhao Guo, Haonan Sun, Yanfeng Song, Degui Wang · 2022 · Frontiers in Cell and Developmental Biology
  35. The peritumor microenvironment: physics and immunity
    Sue Zhang, Kathryn Regan, Julian Najera, Mark W. Grinstaff, Meenal Datta, Hadi Tavakoli Nia · 2023 · Trends in cancer
  36. Micronuclei and Cancer
    Melody Di Bona, Samuel F. Bakhoum · 2024 · Cancer Discovery
  37. Deciphering the role of interferon alpha signaling and microenvironment crosstalk in inflammatory breast cancer
    Olivia K. Provance, Joan S. Lewis-Wambi · 2019 · Breast Cancer Research
  38. Boveri and beyond: Chromothripsis and genomic instability from mitotic errors
    Alice Mazzagatti, Justin L. Engel, Peter Ly · 2023 · Molecular Cell
  39. Noncoding RNA activated by DNA damage (NORAD): Biologic function and mechanisms in human cancers
    Zhi Yang, Yongqiang Zhao, Guofu Lin, Xiangyu Zhou, Xiaofeng Jiang, Haiying Zhao · 2018 · Clinica Chimica Acta
  40. Tumor cells impair immunological synapse formation via central nervous system-enriched metabolite
    Yihong Li, Min Huang, Minger Wang, Yi Wang, Peng Deng, Chunni Li, Jingying Huang, Hui Chen, Zhihao Wei, Qian Ouyang et al. · 2024 · Cancer Cell
  41. ALDH2 Repression Promotes Lung Tumor Progression via Accumulated Acetaldehyde and DNA Damage
    Kaimi Li, Wenzheng Guo, Zhanming Li et al. · 2019 · Neoplasia
  42. Transcriptomic Differences between Primary Colorectal Adenocarcinomas and Distant Metastases Reveal Metastatic Colorectal Cancer Subtypes
    Yasmin Kamal, Stephanie L. Schmit, Hannah J. Hoehn, Christopher Ian Amos, Hildreth Robert Frost · 2019 · Cancer Research
  43. Adult Human Glioblastomas Harbor Radial Glia-like Cells
    Rong Wang, Roshan Sharma, Xiaojuan Shen, Ashley Marie Laughney, Kosuke Funato, Philip J. Clark, Monika Shpokayte, Peter F. Morgenstern, Monalisa Navare, Yichi Xu et al. · 2020 · Stem Cell Reports
  44. Cellular Plasticity: A Route to Senescence Exit and Tumorigenesis
    Hadrien De Blander, Anne‐Pierre Morel, Aruni P. Senaratne, Maria Ouzounova, Alain Puisieux · 2021 · Cancers
  45. Understanding and therapeutically exploiting cGAS/STING signaling in glioblastoma
    Justin Low, Michael C. Brown, Zachary J. Reitman, Joshua D. Bernstock, James M. Markert, Gregory K. Friedman, Matthew S. Waitkus, Michelle L. Bowie, David M. Ashley · 2024 · Journal of Clinical Investigation
  46. Roles for the IKK-Related Kinases TBK1 and IKKε in Cancer
    Joel K. Durand, Qing Hua Zhang, Albert S. Baldwin · 2018 · Cells
  47. Interplay of oxidative stress and antioxidant mechanisms in cancer development and progression
    Klaudia Jomová, Suliman Yousef Alomar, Richard Valko, Lukas Fresser, Eugenie Nepovimová, Kamil Kuča, Marián Valko · 2025 · Archives of Toxicology
  48. Molecular origins of APOBEC-associated mutations in cancer
    Mia Petljak, John Maciejowski · 2020 · DNA repair
  49. Pericentromeric noncoding RNA changes DNA binding of CTCF and inflammatory gene expression in senescence and cancer
    Miyata, Kenichi, Imai, Yoshinori, Hori, Satoshi, Nishio, Mika, Loo, Tze Mun, Okada, Ryo, Yang, Liying, Nakadai, Tomoyoshi, Maruyama, Reo, Fujii, Risa et al. · 2021 · Proceedings of the National Academy of Sciences
  50. cGAS/STING cross-talks with cell cycle and potentiates cancer immunotherapy
    Zi‐Jie Long, Jundan Wang, Jue‐Qiong Xu, Xinxing Lei, Quentin Liu · 2022 · Molecular Therapy
  51. Pharmacogenomic landscape of head and neck squamous cell carcinoma informs precision oncology therapy
    Z. Gu, Yanli Yao, Guizhu Yang, Guo-Pei Zhu, Z. Tian, Rui Wang, Qi Wu, Yu-Jue Wang, Ya-Ping Wu, Lan Chen et al. · 2022 · Science Translational Medicine
  52. From latency to overt bone metastasis in breast cancer: potential for treatment and prevention
    Fernando Salvador, Alicia Llorente Lope, Roger R. Gomis · 2019 · The Journal of Pathology
  53. Chromosome Instability; Implications in Cancer Development, Progression, and Clinical Outcomes
    Raghvendra Vishwakarma, Kirk James McManus · 2020 · Cancers
  54. MASTL overexpression promotes chromosome instability and metastasis in breast cancer
    Rogers, Samuel, McCloy, Rachael A., Parker, Benjamin L., Gallego-Ortega, David, Law, Andrew M. K., Chin, Venessa T., Conway, James R. W., Fey, Dirk, Millar, Ewan K. A., O’Toole, Sandra et al. · 2018 · Oncogene
  55. Relevance of circulating hybrid cells as a non-invasive biomarker for myriad solid tumors
    Matthew S. Dietz, Thomas Lee Sutton, Brett S. Walker, Charles E. Gast, Luai R. Zarour, Sidharth K. Sengupta, John R. Swain, Jennifer R. Eng, Michael S. Parappilly, Kristen E. Limbach et al. · 2021 · Scientific Reports
  56. Structural Chromosome Instability: Types, Origins, Consequences, and Therapeutic Opportunities
    Sebastián Omar Siri, Julieta Martino, Vanesa Gottifredi · 2021 · Cancers
  57. DNA damage induces STING mediated IL-6-STAT3 survival pathway in triple-negative breast cancer cells and decreased survival of breast cancer patients
    Hitesh Vasiyani, Minal Mane, Khushboo Rana, Anjali Shinde, Milton Roy, Jyoti Singh, Dhruv Gohel, Fatema Currim, Ratika Srivastava, Rajesh Kumar Singh · 2022 · APOPTOSIS
  58. Whole-genome doubling drives oncogenic loss of chromatin segregation
    Ruxandra A. Lambuta, Luca Nanni, Yuanlong Liu, Juan Díaz-Miyar, Arvind Iyer, Daniele Tavernari, Natalya Katanayeva, Giovanni Ciriello, Elisa Oricchio · 2023 · Nature
  59. Agonists and Inhibitors of the cGAS-STING Pathway
    Xiaoxuan Yu, Linxiang Cai, Jingyue Yao, Cenming Li, Xiaoyong Wang · 2024 · Molecules
  60. The complexity of immune evasion mechanisms throughout the metastatic cascade
    Nicole M. Haynes, Thomas B Chadwick, Belinda S. Parker · 2024 · Nature Immunology
  61. Multilevel Mechanisms of Cancer Drug Resistance
    Małgorzata Roszkowska · 2024 · International Journal of Molecular Sciences
  62. Mitochondrial DNA signals driving immune responses: Why, How, Where?
    Luca Giordano, Sarah A. Ware, Cláudia Jacques Lagranha, Brett A. Kaufman · 2025 · Cell Communication and Signaling
  63. Potentiating cancer immunotherapies with modular albumin-hitchhiking nanobody–STING agonist conjugates
    Blaise R. Kimmel, Karan Arora, Neil C. Chada, Vijaya Bharti, Alexander J. Kwiatkowski, Jonah E. Finkelstein, Ann Hanna, Emily Nicole Arner, Taylor L. Sheehy, Lucinda E. Pastora et al. · 2025 · Nature Biomedical Engineering
  64. The Evolution of STING Signaling and Its Involvement in Cancer
    Nimi Vashi, Samuel F. W. Bakhoum · 2021 · Trends in Biochemical Sciences
  65. Prostate-specific Membrane Antigen Biology in Lethal Prostate Cancer and its Therapeutic Implications
    Beshara Sheehan, Christina W. Guo, Antje Neeb, Alec Paschalis, Shahneen Kaur Sandhu, Johann Sebastian De Bono · 2021 · European Urology Focus
  66. Single‐cell RNA sequencing reveals cellular and molecular reprograming landscape of gliomas and lung cancer brain metastases
    Hefen Sun, Liangdong Li, I Weng Lao, Xuan Li, Baojin Xu, Yiqun Cao, Wei Jin · 2022 · Clinical and Translational Medicine
  67. Single-cell and spatial genomic landscape of non-small cell lung cancer brain metastases
    Somnath Tagore, Lindsay Caprio, Amit Dipak Amin, Kresimir Bestak, Karan D. Luthria, Edridge K. D’Souza, Irving Barrera, Johannes C. Melms, Sharon Wu, Sinan Abuzaid et al. · 2025 · Nature Medicine
  68. Bacterial-induced cell fusion is a danger signal triggering cGAS–STING pathway via micronuclei formation
    Joanne Wei Kay Ku, Yahua Chen, Bryan Jian Wei Lim, Stephan Gasser, Karen Crasta, Yunn‐Hwen Gan · 2020 · Proceedings of the National Academy of Sciences
  69. Extracellular vesicles and immunogenic stress in cancer
    Qi Wu, Hanpu Zhang, Si Sun, Lijun Wang, Shengrong Sun · 2021 · Cell Death and Disease
  70. APOBEC3A drives deaminase domain-independent chromosomal instability to promote pancreatic cancer metastasis
    Sonja M. Wörmann, Amy Xin Wei Zhang, Fredrik I. Thege, Robert W. Cowan, Dhwani N. Rupani, Runsheng Wang, Sara L. Manning, Chris Gates, Wei-Sheng Wu, Rena Levin-Klein et al. · 2021 · Nature Cancer
  71. Single-cell dissection of remodeled inflammatory ecosystem in primary and metastatic gallbladder carcinoma
    Xiang Wang, Chunliang Liu, Jianan Chen, Lei Chen, Xianwen Ren, Minghui Hou, Xiuliang Cui, Youhai Jiang, Erdong Liu, Yali Zong et al. · 2022 · Cell Discovery
  72. ENPP1 Immunobiology as a Therapeutic Target
    Borja Ruiz‐Fernández de Córdoba, Rafael Martínez‐Monge, Fernando Lecanda · 2023 · Clinical Cancer Research
  73. PARP inhibition and immune modulation: scientific rationale and perspectives for the treatment of gynecologic cancers
    Elizabeth K. Lee, Panagiotis A. Konstantinopoulos · 2020 · Therapeutic Advances in Medical Oncology
  74. “Mitotic Slippage” and Extranuclear DNA in Cancer Chemoresistance: A Focus on Telomeres
    Kristīne Salmiņa, Agnieszka Bojko, Inna Inashkina, Karolina Staniak, Magdalena Dudkowska, Petar Podlesniy, Fēlikss Rūmnieks, Ninel Miriam Vainshelbaum, Dace Pjanova, Ewa Sikora et al. · 2020 · International Journal of Molecular Sciences
  75. Mutation–selection balance and compensatory mechanisms in tumour evolution
    Erez Persi, Yuri I. Wolf, D. Horn, Eytan Ruppin, Francesca Demichelis, Robert A. Gatenby, Robert J. Gillies, Eugene V. Koonin · 2020 · Nature Reviews Genetics
  76. ATR promotes clearance of damaged DNA and damaged cells by rupturing micronuclei
    Yoon Ki Joo, Elizabeth M. Black, Isabelle Trier, Wisse E. Haakma, Lee Zou, Lilian Kabeche · 2023 · Molecular Cell
  77. Mutational game changer: Chromothripsis and its emerging relevance to cancer
    Monique Luijten, Jeannie Xue Ting Lee, Karen Crasta · 2018 · Mutation Research/Reviews in Mutation Research
  78. Local, transient tensile stress on the nuclear membrane causes membrane rupture
    Qiao Zhang, Andrew C. Tamashunas, Ashutosh Agrawal, Mehdi Torbati, Aditya Katiyar, Richard B. Dickinson, Jan Lammerding, Tanmay P. Lele · 2018 · Molecular Biology of the Cell
  79. Proteostasis failure and mitochondrial dysfunction leads to aneuploidy-induced senescence
    Joy, Jery, Barrio, Lara, Santos-Tapia, Celia, Romão, Daniela, Giakoumakis, Nikolaos Nikiforos, Clemente-Ruiz, Marta, Milán, Marco · 2021 · Developmental Cell
  80. Nuclear cGAS: guard or prisoner?
    Carina C. de Oliveira Mann, Karl‐Peter Hopfner · 2021 · The EMBO Journal
  81. Nuclear Envelope Integrity in Health and Disease: Consequences on Genome Instability and Inflammation
    Benoit R. Gauthier, Valentine Comaills · 2021 · International Journal of Molecular Sciences
  82. Genotoxic stress and viral infection induce transient expression of APOBEC3A and pro-inflammatory genes through two distinct pathways
    Sunwoo Oh, Elodie Bournique, Danae Bowen, Pegah R. Jalili, Ambrocio Sanchez, Ian Ward, Alexandra Dananberg, Lavanya Manjunath, Genevieve P. Tran, Bert L. Semler et al. · 2021 · Nature Communications
  83. Nuclear cGAS: sequestration and beyond
    Juli Bai, Feng Liu · 2021 · Protein & Cell
  84. cGAS‐STING signaling in cell death: Mechanisms of action and implications in pathologies
    Yifan Xu, Chen Chen, Zhiyong Liao, Pinglong Xu · 2023 · European Journal of Immunology
  85. What Is Karyotype Coding and Why Is Genomic Topology Important for Cancer and Evolution?
    Christine J. Ye, Lukas Stilgenbauer, Amanda Moy, Guo Liu, Henry H. Heng · 2019 · Frontiers in Genetics
  86. Reverse Transcriptase Inhibition Disrupts Repeat Element Life Cycle in Colorectal Cancer.
    Rajurkar, Mihir, Parikh, Aparna R., Solovyov, Alexander, You, Eunae, Kulkarni, Anupriya S., Chu, Chong, Xu, Katherine H., Jaicks, Christopher, Taylor, Martin S., Wu, Connie et al. · 2022 · Cancer Discovery
  87. Canadian Cannabis Consumption and Patterns of Congenital Anomalies: An Ecological Geospatial Analysis
    Albert Stuart Reece, Gary Kenneth Hulse · 2020 · Journal of Addiction Medicine
  88. Antecedent chromatin organization determines cGAS recruitment to ruptured micronuclei
    Kate M. MacDonald, Shirony Nicholson-Puthenveedu, Maha Mohamed Tageldein, Sarika Khasnis, C.H. Arrowsmith, Shane M. Harding · 2023 · Nature Communications
  89. The Dual Function of KDM5C in Both Gene Transcriptional Activation and Repression Promotes Breast Cancer Cell Growth and Tumorigenesis
    Haifeng Shen, Wenjuan Zhang, Ying Huang, Yaohui He, Guo-Sheng Hu, Lei Wang, Bing‐ling Peng, Yi Jia, Ting‐ting Li, Rui Rong et al. · 2021 · Advanced Science
  90. Understanding the Cause and Consequence of Tumor Heterogeneity
    Subreen A. Khatib, Yotsawat Pomyen, Hien Thanh Dang, Xin Wei Wang · 2020 · Trends in cancer
  91. Genomic control of metastasis
    Saroor A. Patel, Paulo Rodrigues, Ludovic Wesolowski, Sakari Vanharanta · 2020 · British Journal of Cancer
  92. cGAS/STING signalling pathway in senescence and oncogenesis
    Le Yu, Pengda Liu · 2024 · Seminars in Cancer Biology
  93. When breaks get hot: inflammatory signaling in BRCA1/2-mutant cancers
    Marcel A.T.M. van Vugt, Eileen E. Parkes · 2022 · Trends in cancer
  94. Multimodal Spatial Profiling Reveals Immune Suppression and Microenvironment Remodeling in Fallopian Tube Precursors to High-Grade Serous Ovarian Carcinoma
    Tanjina Kader, Jia‐Ren Lin, Clemens B. Hug, Shannon Coy, Yu‐An Chen, Ino de Bruijn, Natalie N. C. Shih, Euihye Jung, Roxanne J. Pelletier, Mariana Lopez Leon et al. · 2024 · Cancer Discovery
  95. SAMHD1 and the innate immune response to cytosolic DNA during DNA replication
    Flavie Coquel, Christoph Neumayer, Yi‐Ching Lin, Philippe Pasero · 2018 · Current Opinion in Immunology
  96. The immunological consequences of radiation‐induced DNA damage
    Anna Clare Wilkins, Emmanuel Christian Patin, Kevin Joseph Harrington, Alan A. Melcher · 2019 · The Journal of Pathology
  97. Estimation of the timing of BAP1 mutation in uveal melanoma progression
    Ogul Ersin Uner, Thonnie Rose O. See, Eszter Szalai, Hans E. Grossniklaus, Gustav Stålhammar · 2021 · Scientific Reports
  98. Regulation of cGAS‐Mediated Immune Responses and Immunotherapy
    Abdullah F. U. H. Saeed, Xinglin Ruan, Hongxin Guan, Jingqian Su, Songying Ouyang · 2020 · Advanced Science
  99. Carotenoids in Cancer Metastasis—Status Quo and Outlook
    Lenka Koklesová, Alena Líšková, Marek Samec, Kevin Zhai, Mariam Abotaleb, Milad Ashrafizadeh, Aranka Brockmueller, Mehdi Shakibaei, Kamil Biringer, Ondrej Bugos et al. · 2020 · Biomolecules
  100. The Emerging Roles of Rad51 in Cancer and Its Potential as a Therapeutic Target
    Ziyi Wang, Renxiang Jia, Linlin Wang, Qiwei Yang, Xiaohai Hu, Qiang Fu, Xinyu Zhang, Wenya Li, Yi Ren · 2022 · Frontiers in Oncology