Chromosomal instability drives metastasis through a cytosolic DNA response

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  1. The interactions between cGAS-STING pathway and pathogens
    Zhangliang Cheng, Tong Dai, Xuelin He, Zhengkui Zhang, Feng Xie, Shuai Wang, Long Zhang, Fangfang Zhou · 2020 · Signal Transduction and Targeted Therapy
  2. Multifaceted functions of STING in human health and disease: from molecular mechanism to targeted strategy
    Zili Zhang, Haifeng Zhou, Xiaohu Ouyang, Yalan Dong, Alexey Sarapultsev, Shanshan Luo, Desheng Hu · 2022 · Signal Transduction and Targeted Therapy
  3. Stem Cell Plasticity and Dormancy in the Development of Cancer Therapy Resistance
    Maria Laura De Angelis, Federica Francescangeli, Filippo La Torre, Ann Zeuner · 2019 · Frontiers in Oncology
  4. Mitochondrial Lon-induced mtDNA leakage contributes to PD-L1–mediated immunoescape via STING-IFN signaling and extracellular vesicles
    An Ning Cheng, Li-Chun Cheng, Cheng‐Liang Kuo, Yu Kang Lo, Han-Yu Chou, Chung–Hsing Chen, Yihao Wang, Tsung‐Hsien Chuang, Shih‐Jung Cheng, Alan Yueh‐Luen Lee · 2020 · Journal for ImmunoTherapy of Cancer
  5. ER-directed TREX1 limits cGAS activation at micronuclei
    Lisa Mohr, Eléonore Toufektchan, Patrick von Morgen, Kevan Chu, Aakanksha R. Kapoor, John Maciejowski · 2021 · Molecular Cell
  6. Role of the cGAS–STING pathway in cancer development and oncotherapeutic approaches
    Khoo, Li Teng, Chen, Liuh‐Yow · 2018 · The EMBO Reports
  7. A genome-wide atlas of co-essential modules assigns function to uncharacterized genes
    Wainberg, Michael, Kamber, Roarke A., Balsubramani, Akshay, Meyers, Robin M., Sinnott-Armstrong, Nasa, Hornburg, Daniel, Jiang, Lihua, Chan, Joanne, Jian, Ruiqi, Gu, Mingxin et al. · 2021 · Nature Genetics
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    Jana Biermann, Johannes C. Melms, Amit Dipak Amin, Yiping Wang, Lindsay Caprio, Alcida Karz, Somnath Tagore, Irving Barrera, Miguel A. Ibarra-Arellano, Massimo Andreatta et al. · 2022 · Cell
  9. LRRC8A:C/E Heteromeric Channels Are Ubiquitous Transporters of cGAMP
    Lauren J. Lahey, Rachel E. Mardjuki, Xianlan Wen, Gaelen T. Hess, Christopher Ritchie, Jacqueline A. Carozza, Volker Böhnert, Merritt C. Maduke, Michael Cory Bassik, Lingyin Li · 2020 · Molecular Cell
  10. Opposing Roles of Type I Interferons in Cancer Immunity
    Giselle M. Boukhaled, Shane M. Harding, David G. Brooks · 2020 · Annual Review of Pathology Mechanisms of Disease
  11. The two sides of chromosomal instability: drivers and brakes in cancer
    Rendy Hosea, Sharon Hillary, Sumera Naqvi, Shourong Wu, Vivi Kasim · 2024 · Signal Transduction and Targeted Therapy
  12. The cGAS/STING Pathway: A Novel Target for Cancer Therapy
    Yu Gan, Xiaoying Li, Shuangze Han, Qi Liang, Xiaoqian Ma, Pengfei Rong, Wei Wang, Wei Li · 2022 · Frontiers in Immunology
  13. The immunostimulatory RNA RN7SL1 enables CAR-T cells to enhance autonomous and endogenous immune function
    Lexus R. Johnson, Daniel Y. Lee, Jacqueline S. Eacret, Darwin Ye, Carl H. June, Andy J. Minn · 2021 · Cell
  14. DNA-stimulated cell death: implications for host defence, inflammatory diseases and cancer
    Søren R. Paludan, Line Sinnathamby Reinert, Veit Hornung · 2019 · Nature reviews. Immunology
  15. Multi-stage mechanisms of tumor metastasis and therapeutic strategies
    Zaoqu Liu, Jingqi Chen, Yuqing Ren, Shutong Liu, Yuhao Ba, Anning Zuo, Peng Luo, Quan Cheng, Hui Xu, Xinwei Han · 2024 · Signal Transduction and Targeted Therapy
  16. Old dogs, new trick: classic cancer therapies activate cGAS
    Seoyun Yum, Minghao Li, Zhijian J. Chen · 2020 · Cell Research
  17. Therapeutic Potential of Combining PARP Inhibitor and Immunotherapy in Solid Tumors
    Vikas, Praveen, Borcherding, Nicholas, Chennamadhavuni, Adithya, Garje, Rohan · 2020 · Frontiers in Oncology
  18. Aneuploidy as a promoter and suppressor of malignant growth
    Anand Vasudevan, Klaske M. Schukken, Erin L. Sausville, Vishruth Girish, Oluwadamilare A. Adebambo, Jason M. Sheltzer · 2021 · Nature reviews. Cancer
  19. Preserving replication fork integrity and competence via the homologous recombination pathway
    Anissia Ait Saada, Sarah Lambert, Antony M. Carr · 2018 · DNA repair
  20. Emerging strategies for treating metastasis
    Mark Esposito, Shridar Ganesan, Yibin Kang · 2021 · Nature Cancer
  21. KDM5 histone demethylases repress immune response via suppression of STING
    Lizhen Wu, Jian Ping Cao, Wesley L. Cai, Sabine M. Lang, John R. Horton, Daniel J. Jansen, Zongzhi Z. Liu, Jocelyn Fang-Yi Chen, Meiling Zhang, Bryan T. Mott et al. · 2018 · PLoS Biology
  22. Mitochondria-localized cGAS suppresses ferroptosis to promote cancer progression
    Shiqiao Qiu, Xiuying Zhong, Xiang Ling Meng, Shiting Li, Xiaoyu Qian, Hui Lu, Jin Cai, Yi Zhang, Mingjie Wang, Zijian Ye et al. · 2023 · Cell Research
  23. The cGAS‒STING pathway in cancer immunity: mechanisms, challenges, and therapeutic implications
    Mengzhou Shen, Xianjie Jiang, Peng Qiu, Linda Oyang, Zongyao Ren, Jiewen Wang, Mingjing Peng, Yujuan Zhou, Xiyun Deng, Qianjin Liao · 2025 · Journal of Hematology & Oncology
  24. Exploring the links between cancer and placenta development
    Vincenzo Costanzo, Alberto Bardelli, Salvatore Siena, Sergio Abrignani · 2018 · Open Biology
  25. Nuclear Membrane Rupture and Its Consequences
    John Maciejowski, Emily M. Hatch · 2020 · Annual Review of Cell and Developmental Biology
  26. Genomic instability, inflammatory signaling and response to cancer immunotherapy
    Chen, Mengting, Linstra, Renske, van Vugt, Marcel A.T.M. · 2022 · Biochimica et Biophysica Acta (BBA) - Reviews on Cancer
  27. DAMP sensing and sterile inflammation: intracellular, intercellular and inter-organ pathways
    Yi Huang, Wei Jiang, Rongbin Zhou · 2024 · Nature reviews. Immunology
  28. The balance of STING signaling orchestrates immunity in cancer
    Klara Rasmussen Bollerup Lanng, Emil Leth Lauridsen, Martin R. Jakobsen · 2024 · Nature Immunology
  29. The cGAS-STING Pathway: A Promising Immunotherapy Target
    Liang Ou, Ao Zhang, Yuxing Cheng, Ying Chen · 2021 · Frontiers in Immunology
  30. Targeting STING to promote antitumor immunity
    Emily N. Chin, Ariana Sulpizio, Luke L. Lairson · 2022 · Trends in Cell Biology
  31. Human SLC46A2 Is the Dominant cGAMP Importer in Extracellular cGAMP-Sensing Macrophages and Monocytes
    Anthony F. Cordova, Christopher Ritchie, Volker Böhnert, Lingyin Li · 2021 · ACS Central Science
  32. The main sources of circulating cell-free DNA: Apoptosis, necrosis and active secretion
    Zijian Hu, Honghong Chen, Yanzhu Long, Ping Li, Yueqing Gu · 2020 · Critical Reviews in Oncology/Hematology
  33. Macrophage-specific inhibition of the histone demethylase JMJD3 decreases STING and pathologic inflammation in diabetic wound repair
    Christopher O. Audu, William James Melvin, Amrita Joshi, Sonya Wolf, Jadie Yoonjoo Moon, Frank M. Davis, Emily C. Barrett, Kevin Dale Mangum, Hongping Deng, Xianying Xing et al. · 2022 · Cellular and Molecular Immunology
  34. Clonal fitness inferred from time-series modelling of single-cell cancer genomes
    Sohrab Salehi, Farhia Kabeer, Nicholas Ceglia, Mirela Andronescu, Marc J. Williams, Kieran R. Campbell, Tehmina Masud, Beixi Wang, Justina Biele, Jazmine Brimhall et al. · 2021 · Nature
  35. Radiation-Induced Chromosomal Aberrations and Immunotherapy: Micronuclei, Cytosolic DNA, and Interferon-Production Pathway
    Marco Durante, Silvia Chiara Formenti · 2018 · Frontiers in Oncology
  36. Transmembrane (TMEM) protein family members: Poorly characterized even if essential for the metastatic process
    Sébastien Marx, Thomas Dal Maso, Jia-Wei Chen, Marina Bury, Johan Wouters, Carine Michiels, Benjamin Le Calvé · 2019 · Seminars in Cancer Biology
  37. Organellar homeostasis and innate immune sensing
    Cassandra R. Harapas, Elina Idiiatullina, Mahmoud Al‐Azab, Katja Hrovat-Schaale, Thomas Reygaerts, Annemarie Steiner, Pawat Laohamonthonkul, Sophia Davidson, Chien‐Hsiung Yu, Lee M. Booty et al. · 2022 · Nature reviews. Immunology
  38. Oncogene-like addiction to aneuploidy in human cancers
    Vishruth Girish, Asad A. Lakhani, Sarah L. Thompson, Christine M. Scaduto, Leanne M. Brown, Ryan A. Hagenson, Erin L. Sausville, Brianna E. Mendelson, Pranav K. Kandikuppa, Devon A. Lukow et al. · 2023 · Science
  39. DNA Replication Stress and Chromosomal Instability: Dangerous Liaisons
    Therese Wilhelm, Maha Said, Valeria Naim · 2020 · Genes
  40. Tumoural activation of TLR3–SLIT2 axis in endothelium drives metastasis
    Bernardo Tavora, Tobias Mederer, Kai J. Wessel, Simon Ruffing, Mahan Sadjadi, Marc Missmahl, Benjamin Nils Ostendorf, Xuhang Liu, Ji-Young Kim, Olav Olsen et al. · 2020 · Nature
  41. Comprehensive Molecular Characterization Identifies Distinct Genomic and Immune Hallmarks of Renal Medullary Carcinoma
    Pavlos Msaouel, Gabriel G. Malouf, Xiaoping Su, Hui Yao, Durga Nand Tripathi, Melinda Soeung, Jianjun Gao, Priya Rao, Cristian Coarfa, Chad J. Creighton et al. · 2019 · Cancer Cell
  42. BRCA2 deficiency instigates cGAS-mediated inflammatory signaling and confers sensitivity to tumor necrosis factor-alpha-mediated cytotoxicity
    Heijink, Anne Margriet, Talens, Francien, Jae, Lucas T., van Gijn, Stephanie E., Fehrmann, Rudolf S. N., Brummelkamp, Thijn R., van Vugt, Marcel A. T. M. · 2019 · Nature Communications
  43. Small but mighty: the causes and consequences of micronucleus rupture
    Mijung Kwon, Mitchell L. Leibowitz, Jae Ho Lee · 2020 · Experimental & Molecular Medicine
  44. Interferons in cancer immunoediting: sculpting metastasis and immunotherapy response
    Michelle von Locquenghien, Catalina Rozalén, Toni Celià-Terrassa · 2021 · Journal of Clinical Investigation
  45. Cell-autonomous inflammation of BRCA1-deficient ovarian cancers drives both tumor-intrinsic immunoreactivity and immune resistance via STING
    Marine Bruand, David Barras, Marco Mina, Eleonora Ghisoni, Matteo Morotti, Evripidis Lanitis, Noémie Fahr, Mathieu Desbuisson, Alizée J Grimm, Hualing Zhang et al. · 2021 · Cell Reports
  46. Immunogenomics Analysis Reveals that TP53 Mutations Inhibit Tumor Immunity in Gastric Cancer
    Zehang Jiang, Zhixian Liu, Mengyuan Li, Cai Chen, Xiaosheng Wang · 2018 · Translational Oncology
  47. Regulation of the cGAS-STING Pathway
    Bing Zhang, Pengbiao Xu, Andrea Ablasser · 2025 · Annual Review of Immunology
  48. STING licensing of type I dendritic cells potentiates antitumor immunity
    Jian Wang, Suxin Li, Maggie Wang, Xu Wang, Shuqing Chen, Zhichen Sun, Xiubao Ren, Gang Huang, Baran D. Sumer, Nan Yan et al. · 2024 · Science Immunology
  49. Chromosomally unstable tumor cells specifically require KIF18A for proliferation
    Carolyn Marquis, Cindy L. Fonseca, Katelyn A. Queen, Lisa M. Wood, Sarah E. Vandal, Heidi L.H. Malaby, Joseph E. Clayton, Jason K. Stumpff · 2021 · Nature Communications
  50. Mitochondria at the interface between neurodegeneration and neuroinflammation
    Verian Bader, Konstanze F. Winklhofer · 2019 · Seminars in Cell and Developmental Biology
  51. Context-dependent functions of pattern recognition receptors in cancer
    Si Ming Man, Brendan John Jenkins · 2022 · Nature reviews. Cancer
  52. Unrestrained ESCRT-III drives micronuclear catastrophe and chromosome fragmentation
    Marina Vietri, Sebastian Wolfgang Schultz, Aurélie Bellanger, Carl M. Jones, Louise I. Petersen, Camilla Raiborg, Ellen Skarpen, Christeen Ramane J. Pedurupillay, Ingrid Kjos, Eline Kip et al. · 2020 · Nature Cell Biology
  53. Mild replication stress causes chromosome mis-segregation via premature centriole disengagement
    Therese Wilhelm, Anna-Maria Olziersky, Daniela Harry, Filipe De Sousa, Hélène Vassal, Anja Eskat, Patrick Meraldi · 2019 · Nature Communications
  54. Radiotherapy and immunology
    Liangliang Wang, Connor M. Lynch, Sean P. Pitroda, András Piffkó, Kaiting Yang, Amy K. Huser, Hua Laura Liang, Ralph R. Weichselbaum · 2024 · The Journal of Experimental Medicine
  55. The cGAS‐STING pathway: The role of self‐DNA sensing in inflammatory lung disease
    Ruihua Ma, Tatiana P. Ortiz Serrano, Jennifer Davis, Andrew D. Prigge, Karen M. Ridge · 2020 · The FASEB Journal
  56. The emerging links between chromosomal instability (CIN), metastasis, inflammation and tumour immunity
    Andréa E. Tijhuis, Sarah C. Johnson, Sarah Elizabeth McClelland · 2019 · Molecular Cytogenetics
  57. Demystifying the cGAS-STING pathway: precision regulation in the tumor immune microenvironment
    Qingyang Wang, Yang Yu, Jing Zhuang, Ruijuan Liu, Changgang Sun · 2025 · Molecular Cancer
  58. Epigenetic dysregulation from chromosomal transit in micronuclei
    Albert S. Agustinus, Duaa Hassan Al-Rawi, Bhargavi Dameracharla, Ramya Raviram, Bailey S.C.L. Jones, Stephanie Stransky, Lorenzo Scipioni, Jens Luebeck, Melody Di Bona, Danguolė Norkūnaitė et al. · 2023 · Nature
  59. Chromosomal Instability in Tumor Initiation and Development
    Duc‐Hiep Bach, Wei Zhang, Anil K. Sood · 2019 · Cancer Research
  60. The molecular origins and pathophysiological consequences of micronuclei: New insights into an age-old problem
    Xihan Guo, Juan Ni, Ziqing Liang, Jinglun Xue, Michael Felix Fenech, Xu Wang · 2018 · Mutation Research/Reviews in Mutation Research
  61. MEDICC2: whole-genome doubling aware copy-number phylogenies for cancer evolution
    Tom L. Kaufmann, Marina Petković, Thomas B.K. Watkins, Emma Colliver, Sofya Laskina, Nisha Thapa, Darlan Conterno Minussi, Nicholas E. Navin, Charles Swanton, Peter Van Loo et al. · 2022 · Genome biology
  62. Genes associated with increased brain metastasis risk in non–small cell lung cancer: Comprehensive genomic profiling of 61 resected brain metastases versus primary non–small cell lung cancer (Guangdong Association Study of Thoracic Oncology 1036)
    Hongsheng Wang, Qiuxiang Ou, Delan Li, Tao Qin, Hua Bao, Xue Hou, Kaicheng Wang, Fang Wang, Qianqian Deng, Liang Jianzhong et al. · 2019 · Cancer
  63. ENPP1’s regulation of extracellular cGAMP is a ubiquitous mechanism of attenuating STING signaling
    Jacqueline A. Carozza, Anthony F. Cordova, Jenifer A. Brown, Yasmeen AlSaif, Volker Böhnert, Xujun Cao, Rachel E. Mardjuki, Gemini M. Skariah, Daniel Fernández, Lingyin Li · 2022 · Proceedings of the National Academy of Sciences
  64. Chromosomal instability as a driver of cancer progression
    Xuelan Chen, Albert S. Agustinus, Jun Li, Melody Di Bona, Samuel F. W. Bakhoum · 2024 · Nature Reviews Genetics
  65. The cGAS/STING/TBK1/IRF3 innate immunity pathway maintains chromosomal stability through regulation of p21 levels
    Abdul Basit, Min-Guk Cho, Eui-Yun Kim, Dohyeong Kwon, Suk‐Jo Kang, Jae‐Ho Lee · 2020 · Experimental & Molecular Medicine
  66. Biochemistry, Cell Biology, and Pathophysiology of the Innate Immune cGAS–cGAMP–STING Pathway
    Christopher Ritchie, Jacqueline A. Carozza, Lingyin Li · 2022 · Annual Review of Biochemistry
  67. The emerging roles of exosomes in the modulation of immune responses in cancer
    Paul A. Kurywchak, Jena L. Tavormina, Raghu Kalluri · 2018 · Genome Medicine
  68. Exosome DNA: Critical regulator of tumor immunity and a diagnostic biomarker
    Aman Sharma, Abiya Johnson · 2019 · Journal of Cellular Physiology
  69. FBXO44 promotes DNA replication-coupled repetitive element silencing in cancer cells
    Shen, Jia Z., Qiu, Zhixin, Wu, Qiulian, Finlay, Darren, Garcia, Guillermina, Sun, Dahui, Rantala, Juha, Barshop, William, Hope, Jennifer L., Gimple, Ryan C. et al. · 2021 · Cell
  70. Chromatin bridges, not micronuclei, activate cGAS after drug-induced mitotic errors in human cells
    Patrick J. Flynn, Peter David Koch, Timothy John Mitchison · 2021 · Proceedings of the National Academy of Sciences
  71. Overcoming cold tumors: a combination strategy of immune checkpoint inhibitors
    Peng Ouyang, Lijuan Wang, Jianlong Wu, Yao Tian, Caiyun Chen, Dengsheng Li, Zengxi Yao, Ruichang Chen, Guoan Xiang, Jin Gong et al. · 2024 · Frontiers in Immunology
  72. STING-dependent paracriny shapes apoptotic priming of breast tumors in response to anti-mitotic treatment
    Steven Lohard, Nathalie Bourgeois, Laurent Maillet, Fabien Gautier, Aurélie Fétiveau, Hamza Lasla, Frédérique Nguyen, Céline Vuillier, Alison Dumont, Agnès Moreau‐Aubry et al. · 2020 · Nature Communications
  73. Cancer metastasis as a non-healing wound
    Matthew Deyell, Christopher Garris, Ashley Marie Laughney · 2021 · British Journal of Cancer
  74. The complementarity of DDR, nucleic acids and anti-tumour immunity
    Anand V. R. Kornepati, Cody M. Rogers, Patrick Sung, Tyler Jay Curiel · 2023 · Nature
  75. Cell cycle checkpoints cooperate to suppress DNA- and RNA-associated molecular pattern recognition and anti-tumor immune responses
    Chen, Jie, Harding, Shane M., Natesan, Ramakrishnan, Tian, Lei, Benci, Joseph L., Li, Weihua, Minn, Andy J., Asangani, Irfan A., Greenberg, Roger A. · 2020 · Cell Reports
  76. Structure-Aided Development of Small-Molecule Inhibitors of ENPP1, the Extracellular Phosphodiesterase of the Immunotransmitter cGAMP
    Jacqueline A. Carozza, Jenifer A. Brown, Volker Böhnert, Daniel Fernández, Yasmeen AlSaif, Rachel E. Mardjuki, Mark A Smith, Lingyin Li · 2020 · Cell chemical biology
  77. Coagulome and the tumor microenvironment: an actionable interplay
    Antoine Galmiche, Janusz Rak, Lubka T. Roumenina, Zuzana Saidak · 2022 · Trends in cancer
  78. TBK1, a central kinase in innate immune sensing of nucleic acids and beyond
    Zhou, Ruyuan, Zhang, Qian, Xu, Pinglong · 2020 · Acta Biochimica et Biophysica Sinica
  79. The translational challenges of precision oncology
    Oriol Pich, Chris Bailey, Thomas B.K. Watkins, Simone Zaccaria, Mariam Jamal‐Hanjani, Charles Swanton · 2022 · Cancer Cell
  80. Clinical applications of STING agonists in cancer immunotherapy: current progress and future prospects
    Bin Wang, Wanpeng Yu, Hongfei Jiang, Xiangwei Meng, Dongmei Tang, Dan Liu · 2024 · Frontiers in Immunology
  81. Comparative Molecular Life History of Spontaneous Canine and Human Gliomas
    Samirkumar B. Amin, Kevin J. Anderson, C. Elizabeth Boudreau, Emmanuel Martínez-Ledesma, Emre Kocakavuk, Kevin C. Johnson, Floris P Barthel, Frederick S. Varn, Cynthia Kassab, Xiaoyang Ling et al. · 2020 · Cancer Cell
  82. Glycolysis drives STING signaling to facilitate dendritic cell antitumor function
    Zhilin Hu, Xiaoyan Yu, Rui Ding, Ben Liu, Chuanjia Gu, Xiuwu Pan, Qiaoqiao Han, Yuerong Zhang, Jie Wan, Xingang Cui et al. · 2023 · Journal of Clinical Investigation
  83. cGAS-STING pathway mediates activation of dendritic cell sensing of immunogenic tumors
    Guohao Li, Xiangqian Zhao, Zuda Zheng, Hucheng Zhang, Yundi Wu, Yangkun Shen, Qi Chen · 2024 · Cellular and Molecular Life Sciences
  84. Signaling Through Nucleic Acid Sensors and Their Roles in Inflammatory Diseases
    Haruna Okude, Daisuke Ori, Taro Kawai · 2021 · Frontiers in Immunology
  85. Nanoscale extracellular vesicle-derived DNA is superior to circulating cell-free DNA for mutation detection in early-stage non-small-cell lung cancer
    Y. Wan, Biao Liu, H. Lei, B. Zhang, Yue Wang, Helen J. Huang, S. Chen, Yue Feng, Lin Zhu, Yuanyuan Gu et al. · 2018 · Annals of Oncology
  86. Molecular and Structural Basis of DNA Sensors in Antiviral Innate Immunity
    Zahid, Ayesha, Ismail, Hazrat, Li, Bofeng, Jin, Tengchuan · 2020 · Frontiers in Immunology
  87. STING Promotes Homeostasis via Regulation of Cell Proliferation and Chromosomal Stability
    Diana Rose E. Rañoa, Ryan C. Widau, Stephen Mallon, Akash D. Parekh, Claudia M. Nicolae, Xiaona Huang, Michael J. Bolt, Ainhoa Arina, Renate Parry, Stephen J. Kron et al. · 2018 · Cancer Research
  88. Colon tumour cell death causes mTOR dependence by paracrine P2X4 stimulation
    Mark Schmitt, Fatih Ceteci, J. R. P. Gupta, Marina Hadzi Pesic, Tim W. Böttger, Adele M. Nicolas, Kilian B. Kennel, Esther Engel, Matthias Schewe, Asude Callak Kirisözü et al. · 2022 · Nature
  89. Single-Chromosomal Gains Can Function as Metastasis Suppressors and Promoters in Colon Cancer
    Anand Vasudevan, Prasamit Saurav Baruah, Joan C. Smith, Zihua Wang, Nicole M. Sayles, Peter Andrews, Jude Kendall, Justin Leu, Narendra Kumar Chunduri, Dan Levy et al. · 2020 · Developmental Cell
  90. cGAS-STING pathway in oncogenesis and cancer therapeutics
    Brandon Yi Da Hoong, Yunn‐Hwen Gan, Haiyan Liu, Ee Sin Chen · 2020 · Oncotarget
  91. Structural Variation in Cancer: Role, Prevalence, and Mechanisms
    Marco Raffaele Cosenza, Bernardo Rodríguez–Martín, Jan O. Korbel · 2022 · Annual Review of Genomics and Human Genetics
  92. Regulation and Consequences of cGAS Activation by Self-DNA
    Christian Zierhut, Hironori Funabiki · 2020 · Trends in Cell Biology
  93. Nucleic Acid Sensors as Therapeutic Targets for Human Disease
    Sarah M. McWhirter, Caroline Anne Jefferies · 2020 · Immunity
  94. Classical epithelial-mesenchymal transition (EMT) and alternative cell death process-driven blebbishield metastatic-witch (BMW) pathways to cancer metastasis
    Goodwin G. Jinesh, Andrew Scott Brohl · 2022 · Signal Transduction and Targeted Therapy
  95. Extracellular vesicle-associated DNA: ten years since its discovery in human blood
    Thupten Tsering, Amélie Nadeau, T.-C. Wu, Kyle Dickinson, Julia Valdemarin Burnier · 2024 · Cell Death and Disease
  96. When cell death goes wrong: inflammatory outcomes of failed apoptosis and mitotic cell death
    Florian J. Bock, Joel S. Riley · 2022 · Cell Death and Differentiation
  97. CGAS is a micronucleophagy receptor for the clearance of micronuclei
    Zhao, Mengmeng, Wang, Fei, Wu, Juehui, Cheng, Yuanna, Cao, Yajuan, Wu, Xiangyang, Ma, Mingtong, Tang, Fen, Liu, Zhi, Liu, Haipeng et al. · 2021 · Autophagy
  98. Properties and Application of Cell-Free DNA as a Clinical Biomarker
    Felipe Silva de Miranda, Valério Garrone Baraúna, Leandro dos Santos, Gustavo Góes Da Costa, Paula Frizera Vassallo, Luciene Cristina Gastalho Campos · 2021 · International Journal of Molecular Sciences
  99. Activation of Tumor-Cell STING Primes NK-Cell Therapy
    Knelson, Erik H., Ivanova, Elena V., Tarannum, Mubin, Campisi, Marco, Lizotte, Patrick H., Booker, Matthew A., Ozgenc, Ismail, Noureddine, Moataz, Meisenheimer, Brittany, Chen, Minyue et al. · 2022 · Cancer Immunology Research
  100. Intratumoral delivery of RIG-I agonist SLR14 induces robust antitumor responses
    Xiaodong Jiang, Viswanathan Muthusamy, Olga Fedorova, Yong Kong, Daniel J. Kim, Marcus Bosenberg, Anna Marie Pyle, Akiko Iwasaki · 2019 · The Journal of Experimental Medicine