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Introduction to RNA Vaccines

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Electroporation – Advantages and Drawbacks for Delivery of Drug, Gene and Vaccine

Bolhassani, A., Khavari, A., & Oraf, Z. (2014) · InTech eBooks · doi:10.5772/58376 · Cited by 46 · see citing works

Scope and challenges of nanoparticle-based mRNA delivery in cancer treatment

Karim, M. E., Haque, S. T., Al-Busaidi, H., Bakhtiar, A., Tha, K. K., Holl, M. M. B., & Chowdhury, E. H. (2022) · Archives of Pharmacal Research · doi:10.1007/s12272-022-01418-x · Cited by 42 · see citing works

Intratumoral electroporation of a self-amplifying RNA expressing IL-12 induces antitumor effects in mouse models of cancer

Silva-Pilipich, N., Lasarte-Cía, A., Lozano, T., Martín-Otal, C., Lasarte, J. J., & Smerdou, C. (2022) · Molecular Therapy — Nucleic Acids · doi:10.1016/j.omtn.2022.07.020 · Cited by 41 · see citing works

Design-of-experiments in vitro transcription yield optimization of self-amplifying RNA

Samnuan, K., Blakney, A. K., McKay, P. F., & Shattock, R. J. (2022) · F1000Research · doi:10.12688/f1000research.75677.1 · Cited by 36 · see citing works

Alphavirus Replicon DNA Expressing HIV Antigens Is an Excellent Prime for Boosting with Recombinant Modified Vaccinia Ankara (MVA) or with HIV gp140 Protein Antigen

Knudsen, M. L., Ljungberg, K., Tatoud, R., Weber, J. N., Estéban, M., & Liljeström, P. (2015) · PLoS ONE · doi:10.1371/journal.pone.0117042 · Cited by 34 · see citing works

Nucleic acid-based vaccine platforms against the coronavirus disease 19 (COVID-19)

Baghban, R., Ghasemian, A., & Mahmoodi, S. (2023) · Archives of Microbiology · doi:10.1007/s00203-023-03480-5 · Cited by 33 · see citing works

Cancer vaccination by electro-gene-transfer

Aurisicchio, L., Mancini, R., & Ciliberto, G. (2013) · Expert Review of Vaccines · doi:10.1586/14760584.2013.836903 · Cited by 29 · see citing works

mRNA cancer vaccines from bench to bedside: a new era in cancer immunotherapy

Shariati, A., Khani, P., Nasri, F., Afkhami, H., Khezrpour, A., Kamrani, S., Shariati, F. S., Alavimanesh, S., & Modarressi, M. H. (2024) · Biomarker Research · doi:10.1186/s40364-024-00692-9 · Cited by 27 · see citing works

Recent Advances in the Molecular Design and Delivery Technology of mRNA for Vaccination Against Infectious Diseases

Lü, Y., Tang, L., Zhang, M., & Liu, C. (2022) · Frontiers in Immunology · doi:10.3389/fimmu.2022.896958 · Cited by 27 · see citing works

Salmonid alphavirus replicon is functional in fish, mammalian and insect cells and in vivo in shrimps (Litopenaeus vannamei)

Olsen, C. M., Pemula, A. K., Braaen, S., Sankaran, K., & Rimstad, E. (2013) · Vaccine · doi:10.1016/j.vaccine.2013.09.058 · Cited by 23 · see citing works

Engineered biomaterials for development of nucleic acid vaccines

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Semliki Forest virus biodistribution in tumor-free and 4T1 mammary tumor-bearing mice: a comparison of transgene delivery by recombinant virus particles and naked RNA replicon

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Multivalent Peptide-Functionalized Bioreducible Polymers for Cellular Delivery of Various RNAs

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Material Design for Next-Generation mRNA Vaccines Using Lipid Nanoparticles

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Controllable self-replicating RNA vaccine delivered intradermally elicits predominantly cellular immunity

Amano, T., Yu, H., Amano, M., Leyder, E. C., Badiola, M., Ray, P., Kim, J., Ko, A. C., Achour, A., Weng, N., et al. (2023) · iScience · doi:10.1016/j.isci.2023.106335 · Cited by 20 · see citing works

Alphavirus Replicon DNA Vectors Expressing Ebola GP and VP40 Antigens Induce Humoral and Cellular Immune Responses in Mice

Ren, S., Wei, Q., Cai, L.-Y., Yang, X., Xing, C., Tan, F., Leavenworth, J. W., Liang, S., & Liu, W. (2018) · Frontiers in Microbiology · doi:10.3389/fmicb.2017.02662 · Cited by 20 · see citing works

Infectious RNA vaccine protects mice against chikungunya virus infection

Szurgot, I., Ljungberg, K., Kümmerer, B. M., & Liljeström, P. (2020) · Scientific Reports · doi:10.1038/s41598-020-78009-7 · Cited by 20 · see citing works

Self-Amplifying Pestivirus Replicon RNA Encoding Influenza Virus Nucleoprotein and Hemagglutinin Promote Humoral and Cellular Immune Responses in Pigs

Démoulins, T., Ruggli, N., Gerber, M., Thomann, L., Ebensen, T., Schulze, K., Guzmán, C. A., & McCullough, K. C. (2021) · Frontiers in Immunology · doi:10.3389/fimmu.2020.622385 · Cited by 20 · see citing works

Protective immune response in mice induced by a suicidal DNA vaccine encoding NTPase-II gene of Toxoplasma gondii

Zheng, L., Hu, Y., Hua, Q., Luo, F., Xie, G., Li, X., Lin, J., Wan, Y., Ren, S., ChangWang, P., et al. (2016) · Acta Tropica · doi:10.1016/j.actatropica.2016.12.004 · Cited by 19 · see citing works

Improving the Repeatability and Efficacy of Intradermal Electroporated Self-Replicating mRNA

Huysmans, H., Temmerman, J. D., Zhong, Z., Cafferty, S. M., Combes, F., Haesebrouck, F., & Sanders, N. N. (2019) · Molecular Therapy — Nucleic Acids · doi:10.1016/j.omtn.2019.06.011 · Cited by 19 · see citing works

Immunogenicity of Semliki Forest virus based self-amplifying RNA expressing Indian HIV-1C genes in mice

Ajbani, S. P., Velhal, S., Kadam, R. B., Patel, V. V., & Bandivdekar, A. H. (2015) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2015.09.010 · Cited by 17 · see citing works

Coatsome-replicon vehicles: Self-replicating RNA vaccines against infectious diseases

Démoulins, T., Schulze, K., Ebensen, T., Techakriengkrai, N., Nedumpun, T., Englezou, P. C., Gerber, M., Hlushchuk, R., Toledo, D., Djonov, V., et al. (2023) · Nanomedicine Nanotechnology Biology and Medicine · doi:10.1016/j.nano.2023.102655 · Cited by 16 · see citing works

Tolerability of a piezoelectric microneedle electroporator in human subjects

Lu, C., Rohilla, P., Felner, E. I., Byagathvalli, G., Azizoğlu, E., Bhamla, M. S., & Prausnitz, M. R. (2024) · Bioengineering & Translational Medicine · doi:10.1002/btm2.10662 · Cited by 13 · see citing works

Breaking barriers: Innovative approaches for skin delivery of RNA therapeutics

Subramanian, G., Kalidasan, K., Quah, S., Qi Chou, G. H., Chan, J., Wacker, M. G., & Sampath, P. (2024) · International Journal of Pharmaceutics · doi:10.1016/j.ijpharm.2024.124435 · Cited by 13 · see citing works

Advanced nanoscale delivery systems for mRNA-based vaccines

Mobasher, M., Ansari, R. A., Castejon, A. M., Barar, J., & Omidi, Y. (2024) · Biochimica et Biophysica Acta (BBA) - General Subjects · doi:10.1016/j.bbagen.2024.130558 · Cited by 13 · see citing works

Technologies for making new vaccines

Ellis, R. W., Rappuoli, R., & Ahmed, S. (2013) · Elsevier eBooks · doi:10.1016/b978-1-4557-0090-5.00013-6 · Cited by 11 · see citing works

Intradermal Electroporation of RNA

Knudsen, M. L., Ljungberg, K., Liljeström, P., & Johansson, D. X. (2014) · Methods in molecular biology · doi:10.1007/978-1-4614-9632-8_13 · Cited by 10 · see citing works

Technologies for Making New Vaccines

Ahmed, S. S., Ellis, R. W., & Rappuoli, R. (2017) · Elsevier eBooks · doi:10.1016/b978-0-323-35761-6.00066-3 · Cited by 10 · see citing works

Construction and evaluation of a self-replicative RNA vaccine against SARS-CoV-2 using yellow fever virus replicon

Nakamura, A., Kotaki, T., Nagai, Y., Takazawa, S., Tokunaga, K., & Kameoka, M. (2022) · PLoS ONE · doi:10.1371/journal.pone.0274829 · Cited by 8 · see citing works

mRNA as a Therapeutics: Understanding mRNA Vaccines

Oğuz, F., & Atmaca, H. (2021) · Advanced Pharmaceutical Bulletin · doi:10.34172/apb.2022.028 · Cited by 7 · see citing works

Alphavirus Replicon Vectors for Prophylactic Applications and Cancer Intervention

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Vaccine development for zoonotic viral diseases caused by positive‑sense single‑stranded RNA viruses belonging to the Coronaviridae and Togaviridae families (Review)

Babaeimarzangou, S. S., Zaker, H., Soleimannezhadbari, E., Shamsi-Gamchi, N., Kazeminia, M., Tarighi, S., Seyedian, H., Tsatsakis, A. M., Spandidos, D. A., & Margina, D. M. (2022) · Experimental and Therapeutic Medicine · doi:10.3892/etm.2022.11741 · Cited by 5 · see citing works

Checkpoint blockade meets gene therapy: Opportunities to improve response and reduce toxicity

Silva-Pilipich, N., Covo-Vergara, Á., Vanrell, L., & Smerdou, C. (2023) · International review of cytology · doi:10.1016/bs.ircmb.2023.05.006 · Cited by 5 · see citing works

Long-term in vivo imaging of translated RNAs for gene therapy

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Hitching a Ride: Enhancing Nucleic Acid Delivery into Target Cells Through Nanoparticles

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RNA Vaccines: The Evolution, Applications, and the Challenges Ahead

Banerji, I., Bhattacharjee, S., Mukherjee, K., & Bhattacharyya, S. N. (2023) · Springer eBooks · doi:10.1007/978-981-19-8520-1_10 · Cited by 3 · see citing works

The Characteristics of RNA Vaccine; its Strengths and Weaknesses

Park, H., Ko, H. L., Jung, S.-Y., Jo, H.-B., & Nam, J. (2016) · Journal of Bacteriology and Virology · doi:10.4167/jbv.2016.46.3.115 · Cited by 3 · see citing works

The alien replicon: Artificial genetic constructs to direct the synthesis of transmissible self‐replicating RNAs

Kochetov, A. V. (2014) · BioEssays · doi:10.1002/bies.201400111 · Cited by 3 · see citing works

Dose of Incorporated Immunodominant Antigen in Recombinant BCG Impacts Modestly on Th1 Immune Response and Protective Efficiency againstMycobacterium tuberculosisin Mice

Ma, H., Wu, K., Liu, F., Yang, H., Kang, H.-V., Chen, N., Yuan, Q., Zhou, W., & Fan, X. (2014) · Journal of Immunology Research · doi:10.1155/2014/196124 · Cited by 3 · see citing works

Semliki Forest Virus Expression System

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Application of self-amplifying mRNA technology in the development of infectious disease vaccines

Li, X., Wang, X., & Zhang, B. (2023) · Chinese Science Bulletin (Chinese Version) · doi:10.1360/tb-2023-0902 · Cited by 2 · see citing works

Therapeutic Applications of Electroporation

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Integrating Context of Tumor Biology and Vaccine Design to Shape Multidimensional Immunotherapies

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Functional analysis of viral and host components of alphavirus replicase complexes

Varjak, M. (2013) · DSpace repository (University of Tartu) · Cited by 1 · see citing works

Alphavirus replicon-based strategies for vaccination

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Design and delivery strategies of alphavirus replicon-based cervical cancer vaccines

van de Wall, M.-N. S. (2018) · University of Groningen research database (University of Groningen / Centre for Information Technology) · Cited by 1 · see citing works

Dissection of virus-host cell interactions in the early response to infection

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RNA vaccines for anti-tumor therapy

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Expressão da proteína de capsídeo recombinante do vírus Semliki Forest e sua associação in vitro com RNA auto replicativo

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New vaccines on the horizon

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Faculty Opinions recommendation of Adjuvant-pulsed mRNA vaccine nanoparticle for immunoprophylactic and therapeutic tumor suppression in mice.

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NUCLEIC ACID VACCINES FOR PREVENTION AND TREATMENT OF INFECTIOUS DISEASES: CURRENT APPLICATIONS

ICAR-IVRI, B., Dutta, S., Sarkar, R., ICAR-IVRI, B., Readdy, M. N., Abhilash, S., Sangma, T. M., Chandra, R. H., & C.V.S.c & A.H, S. (2022) · International Journal of Engineering Applied Sciences and Technology · doi:10.33564/ijeast.2022.v07i03.016

Messenger RNA Therapeutics: Start of a New Era in Medicine

Jain, S., George, A. J., Sharma, V., Singh, G., & Gupta, V. (2022) · RNA technologies · doi:10.1007/978-3-031-08415-7_3

Tissue Nanotransfection in Regenerative Medicine

Xuan, Y., Li, Z., Ghatak, S., & Sen, C. K. (2023) · Elsevier eBooks · doi:10.1016/b978-0-12-820719-2.00038-7

New Generation Self-Replicating RNA Vaccines Derived from Pestivirus Genome

Démoulins, T., Techakriengkrai, N., Ebensen, T., Schulze, K., Liniger, M., Gerber, M., Nedumpun, T., McCullough, K. C., Guzmán, C. A., Suradhat, S., et al. (2024) · Methods in molecular biology · doi:10.1007/978-1-0716-3770-8_4

From genetic code to global health: the impact of nucleic acid vaccines on disease prevention and treatment

Bene, A. D., D’Aniello, A., Mottola, S., Mazzarella, V., Cutolo, R., Campagna, E., Benedetti, R., Altucci, L., Cosconati, S., Maro, S. D., et al. (2025) · RSC Medicinal Chemistry · doi:10.1039/d5md00032g

Novel approaches to immuno-oncology

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Development of therapeutic vaccine strategies and pre-clinical animal tumor models for head and neck cancers

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Formulation et vectorisation d’un ARN messager vaccinal codant l’antigène Gag du VIH-1 à l’aide de nanoparticules biodégradables de poly(acide lactique)

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Electroporation of RNA stimulates immunity to an encoded reporter gene in mice

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Intradermal Electroporation of RNA

Knudsen, M. L., Ljungberg, K., Liljeström, P., & Johansson, D. X. (2014) · Methods in molecular biology · doi:10.1007/978-1-4614-9632-8_13 · Cited by 10 · see citing works

Generation of robust immunity following DNA vaccine immunization enhanced by intradermal electroporation

Smith, T. R. F. (2014) · Journal of Stem Cell Research & Therapy

Cancer therapy using a self-replicating RNA vaccine

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Electroporation-Mediated Intradermal Delivery of DNA Vaccines in Nonhuman Primates

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