The Hippo pathway in organ size control, tissue regeneration and stem cell self-renewal

Inactivation of YAP oncoprotein by the Hippo pathway is involved in cell contact inhibition and tissue growth control

Zhao, B., Wei, X., Li, W., Udan, R. S., Yang, Q., Kim, J., Xie, J., Ikenoue, T., Yu, J., Li, L., et al. (2007) · Genes & Development · doi:10.1101/gad.1602907 · Cited by 3,092

TEAD mediates YAP-dependent gene induction and growth control

Zhao, B., Ye, X., Yu, J., Li, L., Li, W., Li, S., Yu, J., Lin, J. D., Wang, C.-Y., Chinnaiyan, A. M., et al. (2008) · Genes & Development · doi:10.1101/gad.1664408 · Cited by 2,498

Elucidation of a universal size-control mechanism in Drosophila and mammals

Dong, J., Feldmann, G., Huang, J., Wu, S., Zhang, N., Comerford, S. A., Gayyed, M. F., Anders, R. A., Maitra, A., & Pan, D. (2007) · Cell · doi:10.1016/j.cell.2007.07.019 · Cited by 2,370

The Hippo Signaling Pathway in Development and Cancer

Pan, D. (2010) · Developmental Cell · doi:10.1016/j.devcel.2010.09.011 · Cited by 2,317

The Hippo Signaling Pathway Coordinately Regulates Cell Proliferation and Apoptosis by Inactivating Yorkie, the Drosophila Homolog of YAP

Huang, J., Wu, S., Barrera, J. A., Matthews, K. A., & Pan, D. (2005) · Cell · doi:10.1016/j.cell.2005.06.007 · Cited by 1,917

A coordinated phosphorylation by Lats and CK1 regulates YAP stability through SCF β-TRCP

Zhao, B., Li, L., Tumaneng, K., Wang, C.-Y., & Guan, K.-L. (2010) · Genes & Development · doi:10.1101/gad.1843810 · Cited by 1,418

YAP1 increases organ size and expands undifferentiated progenitor cells

Camargo, F. D., Gokhale, S., Johnnidis, J. B., Fu, D., Bell, G. W., Jaenisch, R., & Brummelkamp, T. R. (2007) · Current Biology · doi:10.1016/j.cub.2007.10.039 · Cited by 1,252

The Hippo Signaling Pathway Components Lats and Yap Pattern Tead4 Activity to Distinguish Mouse Trophectoderm from Inner Cell Mass

Nishioka, N., Inoue, K., Adachi, K., Kiyonari, H., Ota, M., Ralston, A., Yabuta, N., Hirahara, S., Stephenson, R. O., Ogonuki, N., et al. (2009) · Developmental Cell · doi:10.1016/j.devcel.2009.02.003 · Cited by 1,120

hippo Encodes a Ste-20 Family Protein Kinase that Restricts Cell Proliferation and Promotes Apoptosis in Conjunction with salvador and warts

Wu, S., Huang, J., Dong, J., & Pan, D. (2003) · Cell · doi:10.1016/s0092-8674(03)00549-x · Cited by 1,120

Hippo Pathway Inhibits Wnt Signaling to Restrain Cardiomyocyte Proliferation and Heart Size

Heallen, T. R., Zhang, M., Wang, J., Bonilla-Claudio, M., Klysik, E., Johnson, R. L., & Martin, J. F. (2011) · Science · doi:10.1126/science.1199010 · Cited by 1,092

Seed Sequence-Matched Controls Reveal Limitations of Small Interfering RNA Knockdown in Functional and Structural Studies of Hepatitis C Virus NS5A-MOBKL1B Interaction

Chung, H.-Y., Gu, M., Buehler, E. C., MacDonald, M. R., & Rice, C. M. (2014) · Journal of Virology · doi:10.1128/jvi.01582-14 · Cited by 24

Atorvastatin Augments Gemcitabine-Mediated Anti-Cancer Effects by Inhibiting Yes-Associated Protein in Human Cholangiocarcinoma Cells

Kitagawa, K., Moriya, K., Kaji, K., Saikawa, S., Sato, S., Nishimura, N., Namisaki, T., Akahane, T., Mitoro, A., & Yoshiji, H. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21207588 · Cited by 23

Role of yes‐associated protein in interleukin‐13 induced nasal remodeling of chronic rhinosinusitis with nasal polyps

Tian, Y., Zheng, R., Liu, J., Tan, K. S., Huang, Z., Zhou, X., Zi, X., Qiu, H., Wang, X., Wang, W., et al. (2020) · Allergy · doi:10.1111/all.14699 · Cited by 23

Hypoxia induces oncogene yes-associated protein 1 nuclear translocation to promote pancreatic ductal adenocarcinoma invasion via epithelial–mesenchymal transition

Wei, H., Xu, Z., Liu, F., Wang, F., Wang, X., Sun, X., & Li, J. (2017) · Tumor Biology · doi:10.1177/1010428317691684 · Cited by 23

Developmental Molecular Biology of the Pancreas

Murtaugh, L. C., Cleaver, O. B., & MacDonald, R. J. (2018) · Springer eBooks · doi:10.1007/978-1-4939-7193-0_4 · Cited by 23

Expression of RASSF6 in kidney and the implication of RASSF6 and the Hippo pathway in the sorbitol-induced apoptosis in renal proximal tubular epithelial cells

Withanage, K., Nakagawa, K., Ikeda, M., Kurihara, H., Kudo, T., Yang, Z., Sakane, A., Sasaki, T., & Hata, Y. (2012) · The Journal of Biochemistry · doi:10.1093/jb/mvs056 · Cited by 23

From Pluripotency to Islets

Hinton, A. C., Hunter, S. E., Reyes, G. X., Fogel, G. B., & King, C. C. (2012) · Advances in genetics · doi:10.1016/b978-0-12-394395-8.00001-3 · Cited by 23

Yes-Associated Protein 1: Role and Treatment Prospects in Orthopedic Degenerative Diseases

Xie, W., Xiao, W., Tang, K., Zhang, L., & Li, Y. (2020) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2020.573455 · Cited by 24

Homoharringtonine Exerts Anti-tumor Effects in Hepatocellular Carcinoma Through Activation of the Hippo Pathway

Wang, H., Wang, R., Huang, D. A., Li, S., Gao, B.-B., Kang, Z., Tang, B., Xie, J., Yan, F., Liang, R., et al. (2021) · Frontiers in Pharmacology · doi:10.3389/fphar.2021.592071 · Cited by 22

Lysophosphatidic Acid Accelerates Bovine In Vitro-Produced Blastocyst Formation through the Hippo/YAP Pathway

Yu, B., van Tol, H. T. A., Oei, C. H. Y., Stout, T. A. E., & Roelen, B. A. J. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22115915 · Cited by 22

Hippo/yes-associated protein signaling functions as a mechanotransducer in regulating vascular homeostasis

Lv, H., & Ai, D. (2021) · Journal of Molecular and Cellular Cardiology · doi:10.1016/j.yjmcc.2021.09.007 · Cited by 25

Current view of liver cancer cell-of-origin and proposed mechanisms precluding its proper determination

Gromowski, T., Lukacs‐Kornek, V., & Cisowski, J. (2023) · Cancer Cell International · doi:10.1186/s12935-022-02843-0 · Cited by 25

Deficiency of skeletal muscle Agrin contributes to the pathogenesis of age-related sarcopenia in mice

Chen, J., Chen, H., Dong, X., Hui, T., Yan, M., Ren, D., Zou, S., Wang, S., Fei, E., Zhang, W., et al. (2024) · Cell Death and Disease · doi:10.1038/s41419-024-06581-1 · Cited by 24

Brief Report: VGLL4 Is a Novel Regulator of Survival in Human Embryonic Stem Cells

Tajonar, A., Maehr, R., Hu, G., Sneddon, J. B., Rivera‐Feliciano, J., Cohen, D. E., Elledge, S. J., & Melton, D. A. (2013) · Stem Cells · doi:10.1002/stem.1445 · Cited by 22

Mst1 and Mst2 Are Essential Regulators of Trophoblast Differentiation and Placenta Morphogenesis

Du, X., Dong, Y., Shi, H., Jiang, L., Kong, S., Shi, D., Sun, L. V., Xu, T., Deng, K., & Tao, W. (2014) · PLoS ONE · doi:10.1371/journal.pone.0090701 · Cited by 22

Metaplastic carcinoma show different expression pattern of YAP compared to triple-negative breast cancer

Kim, H. M., Kim, S. K., Jung, W. H., & Koo, J. S. (2014) · Tumor Biology · doi:10.1007/s13277-014-2735-x · Cited by 22

Taiman acts as a coactivator of Yorkie in the Hippo pathway to promote tissue growth and intestinal regeneration

Wang, C., Yin, M.-X., Wu, W., Dong, L., Wang, S., Lu, Y., Xu, J., Wu, W., Li, S., Zhao, Y., et al. (2016) · Cell Discovery · doi:10.1038/celldisc.2016.6 · Cited by 22

Bacterial Cellulose Shifts Transcriptome and Proteome of Cultured Endothelial Cells Towards Native Differentiation

Feil, G., Horres, R., Schulte, J., Mack, A. F., Wiechmann, S., Arnold, C., Meng, C., Jost, L., Boxleitner, J., Kiessling-Wolf, N., et al. (2017) · Molecular & Cellular Proteomics · doi:10.1074/mcp.ra117.000001 · Cited by 22

Verteporfin Inhibits Cell Proliferation and Induces Apoptosis in Human Leukemia NB4 Cells without Light Activation

Chen, M., Zhong, L., Yao, S., Zhao, Y. C., Liu, L., Li, L., Xu, T., Gan, L., Xiao, C., Shan, Z., et al. (2017) · International Journal of Medical Sciences · doi:10.7150/ijms.19682 · Cited by 23

Non-secreting pituitary tumours characterised by enhanced expression of YAP/TAZ

Xekouki, P., Lodge, E. J., Matschke, J., Santambrogio, A., Apps, J. R., Sharif, A., Jacques, T. S., Aylwin, S. J. B., Prévot, V., Li, R., et al. (2018) · Endocrine Related Cancer · doi:10.1530/erc-18-0330 · Cited by 23

The cancer paradigms of mammalian regeneration: can mammals regenerate as amphibians?

Sarig, R., & Tzahor, E. (2016) · Carcinogenesis · doi:10.1093/carcin/bgw103 · Cited by 22

Peroxisomal cholesterol metabolism regulates yap-signaling, which maintains intestinal epithelial barrier function and is altered in Crohn’s disease

Pinelli, M., Makdissi, S., Scur, M., Parsons, B., Baker, K., Otley, A. R., MacIntyre, B., Nguyen, H. D., Kim, P. K., Stadnyk, A. W., et al. (2024) · Cell Death and Disease · doi:10.1038/s41419-024-06925-x · Cited by 21

YAP1 Takes Over when Oncogenic K-Ras Slumbers

Greten, F. R. (2014) · Cell · doi:10.1016/j.cell.2014.06.021 · Cited by 21

The essential role of TAZ in normal tissue homeostasis

Jeong, M. G., Kim, H. K., & Hwang, E. S. (2021) · Archives of Pharmacal Research · doi:10.1007/s12272-021-01322-w · Cited by 21

Long non-coding RNA LUADT1 promotes nasopharyngeal carcinoma cell proliferation and invasion by downregulating miR-1207-5p

Jiang, N., Zhao, L., Zong, D., Yin, L., Wu, L., Chen, C. Y., Song, X., Zhang, Q., Jiang, X., He, X., et al. (2021) · Bioengineered · doi:10.1080/21655979.2021.2001952 · Cited by 21

Willin/FRMD6: A Multi-Functional Neuronal Protein Associated with Alzheimer’s Disease

Chen, D., Yu, W., Aitken, L., & Gunn‐Moore, F. J. (2021) · Cells · doi:10.3390/cells10113024 · Cited by 21

Adriamycin-Induced Podocyte Injury Disrupts the YAP-TEAD1 Axis and Downregulates Cyr61 and CTGF Expression

Burt, M. A., Kalejaiye, T. D., Bhattacharya, R., Dimitrakakis, N., & Musah, S. (2021) · ACS Chemical Biology · doi:10.1021/acschembio.1c00678 · Cited by 21

The Hippo Pathway Effectors YAP and TAZ Regulate LH Release by Pituitary Gonadotrope Cells in Mice

Lalonde-Larue, A., Boyer, A., Santos, E. C. D., Boerboom, D., Bernard, D. J., & Zamberlam, G. (2021) · Endocrinology · doi:10.1210/endocr/bqab238 · Cited by 21

Role of hepatic stellate cells in liver ischemia-reperfusion injury

Peng, Y., Yin, Q., Yuan, M., Chen, L., Shen, X., Xie, W., & Liu, J. (2022) · Frontiers in Immunology · doi:10.3389/fimmu.2022.891868 · Cited by 24

Estrogen Regulates the Expression and Localization of YAP in the Uterus of Mice

Moon, S., Lee, O., Kim, B., Park, J., Hwang, S., Lee, S., Lee, G., Kim, H., Song, H., Hong, K., et al. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms23179772 · Cited by 19

CD248 ‐expressing cancer‐associated fibroblasts induce non‐small cell lung cancer metastasis via Hippo pathway‐mediated extracellular matrix stiffness

Wu, J., Zhang, Q., Yang, Z., Xu, Y., Liu, X., Wang, X., Peng, J., Xiao, J., Wang, Y., Shang, Z., et al. (2024) · Journal of Cellular and Molecular Medicine · doi:10.1111/jcmm.70025 · Cited by 22

Non-Canonical Roles for Yorkie and Drosophila Inhibitor of Apoptosis 1 in Epithelial Tube Size Control

Robbins, R. M., Gbur, S. C., & Beitel, G. J. (2014) · PLoS ONE · doi:10.1371/journal.pone.0101609 · Cited by 21

Characterization of ypa1 and ypa2, the Schizosaccharomyces pombe Orthologs of the Peptidyl Proyl Isomerases That Activate PP2A, Reveals a Role for Ypa2p in the Regulation of Cytokinesis

Goyal, A., & Simanis, V. (2012) · Genetics · doi:10.1534/genetics.111.138040 · Cited by 21

The Hippo Pathway Regulates Stem Cells During Homeostasis and Regeneration of the Flatworm Macrostomum Lignano

Demircan, T., & Berezikov, E. (2013) · Stem Cells and Development · doi:10.1089/scd.2013.0006 · Cited by 26

Ski regulates Smads and TAZ signaling to suppress lung cancer progression

Xie, M., Wu, X., Zhang, J., Zhang, J., & Li, X. (2017) · Molecular Carcinogenesis · doi:10.1002/mc.22661 · Cited by 21

The prognostic value of YAP1 on clinical outcomes in human cancers

Wu, Y., Hou, Y., Xu, P., Deng, Y., Liu, K., Wang, M., Tian, T., Dai, C., Li, N., Qian, H., et al. (2019) · Aging · doi:10.18632/aging.102358 · Cited by 23

The interplay between centrosomes and the Hippo tumor suppressor pathway

Bolgioni, A. F., & Ganem, N. J. (2015) · Chromosome Research · doi:10.1007/s10577-015-9502-8 · Cited by 21

Ganglioside GM1 promotes contact inhibition of growth by regulating the localization of epidermal growth factor receptor from glycosphingolipid‐enriched microdomain to caveolae

Zhuo, D., & Guan, F. (2019) · Cell Proliferation · doi:10.1111/cpr.12639 · Cited by 21

Strength Under Tension

Bainer, R. O., & Weaver, V. M. (2013) · Science · doi:10.1126/science.1243643 · Cited by 21

Biophysical studies and NMR structure of YAP2 WW domain - LATS1 PPxY motif complexes reveal the basis of their interaction

Verma, A., Fan, J., Finch‐Edmondson, M., Velázquez‐Campoy, A., Balasegaran, S., Sudol, M., & Sivaraman, J. (2018) · Oncotarget · doi:10.18632/oncotarget.23909 · Cited by 19

Sustained Adrenergic Activation of YAP1 Induces Anoikis Resistance in Cervical Cancer Cells

Li, Y., Yang, S., Sadaoui, N. C., Hu, W. M., Dasari, S. K., Mangala, L. S., Sun, Y., Zhao, S., Wang, L., Liu, Y., et al. (2020) · iScience · doi:10.1016/j.isci.2020.101289 · Cited by 20

Signaling Pathways in Inflammation and Cardiovascular Diseases: An Update of Therapeutic Strategies

Cucu, I. (2022) · Immuno · doi:10.3390/immuno2040039 · Cited by 23

Hippo signaling in acute kidney injury to chronic kidney disease transition: Current understandings and future targets

Habshi, T., Shelke, V., Kale, A., Lech, M., & Gaikwad, A. B. (2023) · Drug Discovery Today · doi:10.1016/j.drudis.2023.103649 · Cited by 20

Yes-Associated Protein Mediates the Transition from Inflammation to Fibrosis in Graves' Orbitopathy

Ko, J., Kim, Y. J., Choi, S. H., Lee, C. S., & Yoon, J. S. (2023) · Thyroid · doi:10.1089/thy.2023.0309 · Cited by 21

The YAP1/TAZ-TEAD transcriptional network regulates gene expression at neuromuscular junctions in skeletal muscle fibers

Gessler, L., Huraskin, D., Jian, Y., Eiber, N., Hu, Z., Prószyński, T. J., & Hashemolhosseini, S. (2023) · Nucleic Acids Research · doi:10.1093/nar/gkad1124 · Cited by 20

Heterogeneous Contributing Factors in MPM Disease Development and Progression: Biological Advances and Clinical Implications

Tolani, B., Acevedo, L. A., Hoang, N. T., & He, B. (2018) · International Journal of Molecular Sciences · doi:10.3390/ijms19010238 · Cited by 20

Tetrandrine induces apoptosis in human neuroblastoma through regulating the Hippo/YAP signaling pathway

Zhao, Q., Jia, X., Zhang, Y., Dong, Y., Lei, Y., Tan, X., Williamson, R. A., Wang, A., Zhang, D., & Ma, J. (2019) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2019.04.075 · Cited by 20

YAP/TAZ: a promising target for squamous cell carcinoma treatment

Dong, X., Meng, L., Liu, P., Ji, R., Su, X., Xin, Y., & Jiang, X. M. (2019) · Cancer Management and Research · doi:10.2147/cmar.s197921 · Cited by 23

MicroRNA sequences modulating inflammation and lipid accumulation in macrophage “foam” cells: Implications for atherosclerosis

Lightbody, R. J., Taylor, J. M. W., Dempsie, Y., & Graham, A. (2020) · World Journal of Cardiology · doi:10.4330/wjc.v12.i7.303 · Cited by 20

YAP/TAZ affects the development of pulmonary fibrosis by regulating multiple signaling pathways

Zhu, T., Ma, Z., Wang, H., Jia, X., Wu, Y., Fu, L., Li, Z., Zhang, C., & Yu, G. (2020) · Molecular and Cellular Biochemistry · doi:10.1007/s11010-020-03866-9 · Cited by 20

FoxO4 negatively modulates USP10 transcription to aggravate the apoptosis and oxidative stress of hypoxia/reoxygenation-induced cardiomyocytes by regulating the Hippo/YAP pathway

Huang, J., Liu, Y., Wang, M., Wang, R., Ling, H., & Yang, Y. (2021) · Journal of Bioenergetics and Biomembranes · doi:10.1007/s10863-021-09910-7 · Cited by 20

Somatic ERK activation during transit amplification is essential for maintaining the synchrony of germline divisions in Drosophila testis

Gupta, S., Varshney, B., Chatterjee, S., & Ray, K. (2018) · Open Biology · doi:10.1098/rsob.180033 · Cited by 18

Age-related elevation of HGF is driven by the reduction of fibroblast size in a YAP/TAZ/CCN2 axis-dependent manner

Xiang, Y., Qin, Z., Yang, Y., Fisher, G. J., & Quan, T. (2021) · Journal of Dermatological Science · doi:10.1016/j.jdermsci.2021.02.003 · Cited by 18

Circular RNAs play roles in regulatory networks of cell signaling pathways in human cancers

Almouh, M., Razmara, E., Bitaraf, A., Ghazimoradi, M. H., Hassan, Z. M., & Babashah, S. (2022) · Life Sciences · doi:10.1016/j.lfs.2022.120975 · Cited by 19

The Emerging Role of Ubiquitin-Specific Protease 36 (USP36) in Cancer and Beyond

Niu, M.-Y., Liu, Y.-J., Shi, J., Chen, R.-Y., Zhang, S., Li, C.-Y., Cao, J.-F., Yang, G., & Chen, J. (2024) · Biomolecules · doi:10.3390/biom14050572 · Cited by 20

Phosphorylation of Tyr188 in the WW domain of YAP1 plays an essential role in YAP1-induced cellular transformation

Li, Y.-W., Guo, J., Shen, H., Li, J., Yang, N., Frangou, C. G., Wilson, K. E., Zhang, Y., Mussell, A. L., Sudol, M., et al. (2016) · Cell Cycle · doi:10.1080/15384101.2016.1207836 · Cited by 19

Small-Molecule Inhibitors of Protein–Protein Interactions

Liu, Z., Chen, H., Wold, E. A., & Zhou, J. (2016) · Elsevier eBooks · doi:10.1016/b978-0-12-409547-2.12326-1 · Cited by 19

Integrated miRNA-seq analysis reveals the molecular mechanism underlying the effect of acupuncture on endometrial receptivity in patients undergoing fertilization: embryo transplantation

Mu, Y., Li, Q., Cheng, J., Shen, J., Jin, X., Xie, Z., Gao, Z., Zhang, W., Hua, Q., Xia, L., et al. (2019) · 3 Biotech · doi:10.1007/s13205-019-1990-3 · Cited by 19

miR-550-1 functions as a tumor suppressor in acute myeloid leukemia via the hippo signaling pathway

Hu, C., Yu, M., Li, C., Wang, Y., Li, X., Ulrich, B. C., Su, R. J., Dong, L., Weng, H., Huang, H., et al. (2020) · International Journal of Biological Sciences · doi:10.7150/ijbs.44365 · Cited by 19

Molecular evidence for better efficacy of hypocrellin A and oleanolic acid combination in suppression of HCC growth

Wang, L., Wang, J., Cao, Y., Li, W., Wang, Y., Xu, J., & Xu, G. (2018) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2018.10.042 · Cited by 19

Sphere-induced reprogramming of RPE cells into dual-potential RPE stem-like cells

Chen, F., Liu, X., Chen, Y., Liu, J. Y., Lü, H., Wang, W., Lu, X., Dean, K. C., Gao, L., Kaplan, H. J., et al. (2020) · EBioMedicine · doi:10.1016/j.ebiom.2019.102618 · Cited by 19

DLC1 deficiency and YAP signaling drive endothelial cell contact inhibition of growth and tumorigenesis

Ritchey, L., Ha, T., Otsuka, A., Kabashima, K., Wang, D., Wang, Y., Lowy, D. R., & Tosato, G. (2019) · Oncogene · doi:10.1038/s41388-019-0944-x · Cited by 17

Chinese Propolis Suppressed Pancreatic Cancer Panc-1 Cells Proliferation and Migration via Hippo-YAP Pathway

Tao, L., Chen, X., Zheng, Y., Wu, Y., Jiang, X., You, M., Li, S., & Hu, F. (2021) · Molecules · doi:10.3390/molecules26092803 · Cited by 18

Self-Sustained Regulation or Self-Perpetuating Dysregulation: ROS-dependent HIF-YAP-Notch Signaling as a Double-Edged Sword on Stem Cell Physiology and Tumorigenesis

Guo, C. (2022) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2022.862791 · Cited by 19

The Hippo pathway and its correlation with acute kidney injury

Zhang, C., 上海交通大学附属第一人民医院肾内科, 上. 2., Li, C., Xu, K., Zheng, Z., Cheng, G., Wu, H., Liu, J., & 复旦大学基础医学院病理科, 上. 2. (2022) · 动物学研究 · doi:10.24272/j.issn.2095-8137.2022.110 · Cited by 18

Exosomes secreted from bone marrow mesenchymal stem cells suppress cardiomyocyte hypertrophy through Hippo-YAP pathway in heart failure

Ren, Y., Wu, Y., He, W., Tian, Y., & Zhao, X. (2023) · Genetics and Molecular Biology · doi:10.1590/1678-4685-gmb-2022-0221 · Cited by 18

Mechanosensitive Piezo1 channels promote neurogenic bladder fibrosis via regulating TGF-β1/smad and Hippo/YAP1 pathways

Feng, S., Yu, Z., Yang, Y., Xiong, Q., Yan, X., & Bi, Y. (2024) · Experimental Cell Research · doi:10.1016/j.yexcr.2024.114218 · Cited by 19

Lats1/2 -Mediated Alteration of Hippo Signaling Pathway Regulates the Fate of Bone Marrow-Derived Mesenchymal Stem Cells

Li, L., Dong, L., Wang, Y., Zhang, X., & Yan, J. (2018) · BioMed Research International · doi:10.1155/2018/4387932 · Cited by 18

Genomic analysis reveals selection signatures of the Wannan Black pig during domestication and breeding

Zhang, W., Yang, M., Wang, Y., Wu, X., Zhang, X., Ding, Y., & Yin, Z. (2019) · Asian-Australasian Journal of Animal Sciences · doi:10.5713/ajas.19.0289 · Cited by 18

Effects of Dinotefuran on Brain miRNA Expression Profiles in Young Adult Honey Bees (Hymenopptera: Apidae)

Huang, M., Dong, J., Guo, H., & Wang, D. (2020) · Journal of Insect Science · doi:10.1093/jisesa/ieaa131 · Cited by 18

The Balance between Differentiation and Terminal Differentiation Maintains Oral Epithelial Homeostasis

Bai, Y., Boath, J., White, G. R., Kariyawasam, U. G. I. U., Farah, C. S., & Darido, C. (2021) · Cancers · doi:10.3390/cancers13205123 · Cited by 18

CKAP4 contributes to the progression of vascular calcification (VC) in chronic kidney disease (CKD) by modulating YAP phosphorylation and MMP2 expression

Shi, Y., Jin, X., Yang, M. G., Jia, J., Yao, H., Yuan, W., Wang, K., & Rong, S. (2022) · Cellular Signalling · doi:10.1016/j.cellsig.2022.110270 · Cited by 18

The Homeodomain Iroquois Proteins Control Cell Cycle Progression and Regulate the Size of Developmental Fields

Barrios, N., González-Pérez, E., Hernández, R., & Campuzano, S. (2015) · PLoS Genetics · doi:10.1371/journal.pgen.1005463 · Cited by 18

Histone Acetylation-Mediated Regulation of the Hippo Pathway

Basu, D., Reyes‐Múgica, M., & Rebbaa, A. (2013) · PLoS ONE · doi:10.1371/journal.pone.0062478 · Cited by 20

Fluid Mechanics as a Driver of Tissue-Scale Mechanical Signaling in Organogenesis

Gilbert, R. M., Morgan, J. T., Marcin, E. S., & Gleghorn, J. P. (2016) · Current Pathobiology Reports · doi:10.1007/s40139-016-0117-3 · Cited by 18

Emerging role of Hippo signalling in pancreatic biology: YAP re-expression and plausible link to islet cell apoptosis and replication

Sharma, A., Yerra, V. G., & Kumar, A. (2016) · Biochimie · doi:10.1016/j.biochi.2016.12.009 · Cited by 18

Combined Ischemic Preconditioning and Resveratrol Improved Bloodbrain Barrier Breakdown via Hippo/YAP/TAZ Signaling Pathway

Hong, G., Yan, Y., Zhong, Y., Chen, J., Tong, F., & Ma, Q. (2019) · CNS & Neurological Disorders - Drug Targets · doi:10.2174/1871527318666191021144126 · Cited by 18

Age and Behavior-Dependent Differential miRNAs Expression in the Hypopharyngeal Glands of Honeybees (Apis mellifera L.)

Shi, T., Zhu, Y., Liu, P., Liang, Y. S., Jiang, X., Cao, H., & Yu, L. (2021) · Insects · doi:10.3390/insects12090764 · Cited by 17

Transcriptomic Analysis Reveals a Link Between Hippo Signaling Pathway and Macrophages in Lungs of Mice with OVA-Induced Allergic Asthma

Xiao, H., Zhang, Q.-N., Sun, Q.-X., Li, L.-D., Xu, S.-Y., & Li, C.-Q. (2022) · Journal of Inflammation Research · doi:10.2147/jir.s346505 · Cited by 17

Bufalin inhibits the proliferation of lung cancer cells by suppressing Hippo-YAP pathway

Qian, Z., Tian, X., Miao, Y., Xu, X., Cheng, X., Wu, M., & Yu, Y. (2023) · Cellular Signalling · doi:10.1016/j.cellsig.2023.110746 · Cited by 17

Pathogenetic and Prognostic Significance of Inactivation of RASSF Proteins in Human Hepatocellular Carcinoma

Calvisi, D. F., Evert, M., & Dombrowski, F. (2012) · Molecular Biology International · doi:10.1155/2012/849874 · Cited by 17

Introducing STRaNDs: shuttling transcriptional regulators that are non-DNA binding

Lu, M. M., Muers, M. R., & Lü, X. (2016) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm.2016.41 · Cited by 18

Biomechanical strain-induced modulation of proliferation coincides with an ERK1/2-independent nuclear YAP localization

Hülter-Hassler, D., Wein, M., Schulz, S., Proksch, S., Steinberg, T., Jung, B. A., & Tomakidi, P. (2017) · Experimental Cell Research · doi:10.1016/j.yexcr.2017.10.006 · Cited by 17

Polo‐Like Kinase 2 is Dynamically Regulated to Coordinate Proliferation and Early Lineage Specification Downstream of Yes‐Associated Protein 1 in Cardiac Progenitor Cells

Mochizuki, M., Lorenz, V., Ivánek, R., Verde, G. D., Gaudiello, E., Marsano, A., Pfister, O., & Kuster, G. M. (2017) · Journal of the American Heart Association · doi:10.1161/jaha.117.005920 · Cited by 17

Alternative Splicing in the Hippo Pathway—Implications for Disease and Potential Therapeutic Targets

Porazinski, S. R., & Ladomery, M. (2018) · Genes · doi:10.3390/genes9030161 · Cited by 16

PM2.5-associated nitro-PAH exposure promotes tumor cell metastasis through Hippo-YAP mediated transcriptional regulation

Gao, R., Yun, Y., Cai, Z., & Sang, N. (2019) · The Science of The Total Environment · doi:10.1016/j.scitotenv.2019.04.420 · Cited by 17

Harnessing the Potential Synergistic Interplay Between Photosensitizer Dark Toxicity and Chemotherapy

Baglo, Y., Sorrin, A. J., Liang, B. J., & Huang, H. (2019) · Photochemistry and Photobiology · doi:10.1111/php.13196 · Cited by 17

Sestrin2 inhibits YAP activation and negatively regulates corneal epithelial cell proliferation

Lee, J., Park, H., Cho, K. J., & Lyu, J. (2020) · Experimental & Molecular Medicine · doi:10.1038/s12276-020-0446-5 · Cited by 17

MiR-25-3p Serves as an Oncogenic MicroRNA by Downregulating the Expression of Merlin in Osteosarcoma

Rao, H.-C., Wu, Z., Wei, S.-D., Jiang, Y., Guo, Q.-X., Wang, J., Chang-xian, C., & Yang, H. (2020) · Cancer Management and Research · doi:10.2147/cmar.s262245 · Cited by 17

The Act of Controlling Adult Stem Cell Dynamics: Insights from Animal Models

Krishnan, M., Kumar, S., Kangale, L. J., Ghigo, É., & Abnave, P. (2021) · Biomolecules · doi:10.3390/biom11050667 · Cited by 16

hucMSC‐sEVs‐Derived 14‐3‐3ζ Serves as a Bridge between YAP and Autophagy in Diabetic Kidney Disease

Yin, S., Liu, W., Ji, C., Zhu, Y. X., Shan, Y., Zhou, Z., Chen, W., Zhang, L., Sun, Z., Zhou, W., et al. (2022) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2022/3281896 · Cited by 17

Cell-Autonomous and Non-cell-autonomous Function of Hox Genes Specify Segmental Neuroblast Identity in the Gnathal Region of the Embryonic CNS in Drosophila

Becker, H., Renner, S., Technau, G. M., & Berger, C. (2016) · PLoS Genetics · doi:10.1371/journal.pgen.1005961 · Cited by 18

Ezrin regulates skin fibroblast size/mechanical properties and YAP-dependent proliferation

Quan, C., Yan, Y., Qin, Z., Lin, Z., & Quan, T. (2017) · Journal of Cell Communication and Signaling · doi:10.1007/s12079-017-0406-6 · Cited by 18

Mechano-growth factor protects against mechanical overload induced damage and promotes migration of growth plate chondrocytes through RhoA/YAP pathway

Jing, X., Ye, Y., Bao, Y., Zhang, J., Huang, J., Wang, R., Guo, J., & Guo, F. (2018) · Experimental Cell Research · doi:10.1016/j.yexcr.2018.02.021 · Cited by 17

Stochastic cellular automata model of neurosphere growth: Roles of proliferative potential, contact inhibition, cell death, and phagocytosis

Sipahi, R., & Zupanc, G. K. H. (2018) · Journal of Theoretical Biology · doi:10.1016/j.jtbi.2018.02.025 · Cited by 19

Resveratrol Reverses Osteogenic Decline of Bone Marrow Mesenchymal Stem Cells Via Upregulation of YAP Expression in Inflammatory Environment

Wang, Z., Li, L., Gu, W., Mao, Y., & Wang, T. (2021) · Stem Cells and Development · doi:10.1089/scd.2021.0195 · Cited by 16

Differential age-related transcriptomic analysis of ovarian granulosa cells in Kazakh horses

Ren, W., Wang, J., Zeng, Y., Wang, T., Meng, J., & Yao, X. (2024) · Frontiers in Endocrinology · doi:10.3389/fendo.2024.1346260 · Cited by 16

Targeting NF2-Hippo/Yap signaling pathway for cardioprotection after ischemia/reperfusion injury

Mia, M. M., Chelakkot-Govindalayathil, A.-L., & Singh, M. K. (2016) · Annals of Translational Medicine · doi:10.21037/atm.2016.11.85 · Cited by 16

Ocular phenotypic consequences of a single copy deletion of the Yap1 gene (Yap1 +/-) in mice.

Kim, S.-H., Thomasy, S. M., Raghunathan, V. K., Teixeira, L. B. C., Moshiri, A., FitzGerald, P., & Murphy, C. J. (2019) · Europe PMC (PubMed Central) · Cited by 16

Novel approaches to fertility restoration in women with premature ovarian insufficiency

Rosario, R., & Anderson, R. A. (2021) · Climacteric · doi:10.1080/13697137.2020.1856806 · Cited by 16

The history and regulatory mechanism of the Hippo pathway

Kim, W., & Jho, E. (2018) · BMB Reports · doi:10.5483/bmbrep.2018.51.3.022 · Cited by 81

Hippo signaling in organ size controlPreprint

Pan, D. (2007) · Genes & Development · doi:10.1101/gad.1536007 · Cited by 665

The Hippo pathway in organ development, homeostasis, and regeneration

Fu, V. X., Plouffe, S. W., & Guan, K. (2017) · Current Opinion in Cell Biology · doi:10.1016/j.ceb.2017.12.012 · Cited by 230

Hippo Growth Control Pathway and Organ Size

Waghmare, I., Verghese, S., & Kango‐Singh, M. (2015) · Wiley eBooks · doi:10.1002/9780470015902.a0026054

The Hippo superhighway: signaling crossroads converging on the Hippo/Yap pathway in stem cells and development

Barry, E. R., & Camargo, F. D. (2013) · Current Opinion in Cell Biology · doi:10.1016/j.ceb.2012.12.006 · Cited by 214