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Morphogenesis and oncogenesis of MCF-10A mammary epithelial acini grown in three-dimensional basement membrane cultures

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The Hippo Signaling Pathway Coordinately Regulates Cell Proliferation and Apoptosis by Inactivating Yorkie, the Drosophila Homolog of YAP

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A Lentiviral RNAi Library for Human and Mouse Genes Applied to an Arrayed Viral High-Content Screen

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YAP1 increases organ size and expands undifferentiated progenitor cells

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hippo Encodes a Ste-20 Family Protein Kinase that Restricts Cell Proliferation and Promotes Apoptosis in Conjunction with salvador and warts

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Identification and validation of oncogenes in liver cancer using an integrative oncogenomic approach

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The Drosophila Mst Ortholog, hippo, Restricts Growth and Cell Proliferation and Promotes Apoptosis

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Transforming properties of YAP , a candidate oncogene on the chromosome 11q22 amplicon

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salvador Promotes Both Cell Cycle Exit and Apoptosis in Drosophila and Is Mutated in Human Cancer Cell Lines

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Akt Phosphorylates the Yes-Associated Protein, YAP, to Induce Interaction with 14-3-3 and Attenuation of p73-Mediated Apoptosis

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Tumor Suppressor LATS1 Is a Negative Regulator of Oncogene YAP

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Hippo promotes proliferation arrest and apoptosis in the Salvador/Warts pathway

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TEAD/TEF transcription factors utilize the activation domain of YAP65, a Src/Yes-associated protein localized in the cytoplasm

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The TEAD/TEF Family Protein Scalloped Mediates Transcriptional Output of the Hippo Growth-Regulatory Pathway

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The TEAD/TEF family of transcription factor Scalloped mediates Hippo signaling in organ size control

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The Salvador–Warts–Hippo pathway — an emerging tumour-suppressor network

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Control of Cell Proliferation and Apoptosis by Mob as Tumor Suppressor, Mats

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A WW domain‐containing Yes‐associated protein (YAP) is a novel transcriptional co‐activator

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WW Domain-containing Protein YAP Associates with ErbB-4 and Acts as a Co-transcriptional Activator for the Carboxyl-terminal Fragment of ErbB-4 That Translocates to the Nucleus

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SCALLOPED Interacts with YORKIE, the Nuclear Effector of the Hippo Tumor-Suppressor Pathway in Drosophila

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Mice heterozygous for a mutation at the Nf2 tumor suppressor locus develop a range of highly metastatic tumorsPreprint

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Filling out the Hippo pathway

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A Polycomb Repression Signature in Metastatic Prostate Cancer Predicts Cancer Outcome

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From Cell Structure to Transcription: Hippo Forges a New Path

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Elevated levels of connective tissue growth factor, WISP-1, and CYR61 in primary breast cancers associated with more advanced features.

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Membrane organization and tumorigenesis—the NF2 tumor suppressor, MerlinPreprint

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Regulation of Imaginal Disc Growth by Tumor-Suppressor Genes in Drosophila

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Molecular interactions between Vestigial and Scalloped promote wing formation in DrosophilaPreprint

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Connective Tissue Growth Factor–Specific Monoclonal Antibody Therapy Inhibits Pancreatic Tumor Growth and Metastasis

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A novel TEAD1 mutation is the causative allele in Sveinsson's chorioretinal atrophy (helicoid peripapillary chorioretinal degeneration)

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Insights into transcription enhancer factor 1 (TEF-1) activity from the solution structure of the TEA domain

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A Sveinsson’s chorioretinal atrophy-associated missense mutation in mouse Tead1 affects its interaction with the co-factors YAP and TAZ

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Role of YAP/TAZ in mechanotransduction

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Hippo pathway in organ size control, tissue homeostasis, and cancer

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YAP/TAZ at the Roots of Cancer

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Mechanisms of Hippo pathway regulation

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Regulation of the Hippo-YAP Pathway by G-Protein-Coupled Receptor Signaling

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Genetic and pharmacological disruption of the TEAD–YAP complex suppresses the oncogenic activity of YAP

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Mechanotransduction and YAP-dependent matrix remodelling is required for the generation and maintenance of cancer-associated fibroblasts

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Force triggers YAP nuclear entry by regulating transport across nuclear pores

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A coordinated phosphorylation by Lats and CK1 regulates YAP stability through SCF ^β-TRCP

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The Hippo transducer TAZ confers cancer stem cell-related traits on breast cancer cells

Cordenonsi, M., Zanconato, F., Azzolin, L., Forcato, M., Rosato, A., Frasson, C., Inui, M., Montagner, M., Parenti, A. R., Poletti, A., et al. (2011) · Cell · doi:10.1016/j.cell.2011.09.048 · Cited by 1,381 · see citing works

Genome-wide association between YAP/TAZ/TEAD and AP-1 at enhancers drives oncogenic growth

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The Hippo pathway in organ size control, tissue regeneration and stem cell self-renewal

Zhao, B., Tumaneng, K., & Guan, K.-L. (2011) · Nature Cell Biology · doi:10.1038/ncb2303 · Cited by 1,205 · see citing works

Transduction of mechanical and cytoskeletal cues by YAP and TAZ

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Targeting the Hippo pathway in cancer, fibrosis, wound healing and regenerative medicine

Dey, A., Varelas, X., & Guan, K.-L. (2020) · Nature Reviews Drug Discovery · doi:10.1038/s41573-020-0070-z · Cited by 860 · see citing works

The Hippo Signaling Pathway in Development and Disease

Zheng, Y., & Pan, D. (2019) · Developmental Cell · doi:10.1016/j.devcel.2019.06.003 · Cited by 867 · see citing works

Mechanosignaling through YAP and TAZ drives fibroblast activation and fibrosis

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Hippo Pathway Activity Influences Liver Cell Fate

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β-Catenin-Driven Cancers Require a YAP1 Transcriptional Complex for Survival and Tumorigenesis

Rosenbluh, J., Nijhawan, D., Cox, A. G., Li, X., Neal, J. T., Schafer, E. J., Zack, T. I., Wang, X., Tsherniak, A., Schinzel, A. C., et al. (2012) · Cell · doi:10.1016/j.cell.2012.11.026 · Cited by 757 · see citing works

KRAS and YAP1 Converge to Regulate EMT and Tumor Survival

Shao, D. D., Xue, W., Krall, E. B., Bhutkar, A., Piccioni, F., Wang, X., Schinzel, A. C., Sood, S., Rosenbluh, J., Kim, J. W., et al. (2014) · Cell · doi:10.1016/j.cell.2014.06.004 · Cited by 744 · see citing works

Yap1 Activation Enables Bypass of Oncogenic Kras Addiction in Pancreatic Cancer

Kapoor, A., Yao, W., Ying, H., Hua, S., Liewen, A., Wang, Q., Zhong, Y., Wu, C.-J., Sadanandam, A., Hu, B., et al. (2014) · Cell · doi:10.1016/j.cell.2014.06.003 · Cited by 716 · see citing works

Cellular energy stress induces AMPK-mediated regulation of YAP and the Hippo pathway

Mo, J.-S., Meng, Z., Kim, Y. C., Park, H. W., Hansen, C. G., Kim, S., Lim, D.-S., & Guan, K.-L. (2015) · Nature Cell Biology · doi:10.1038/ncb3111 · Cited by 557 · see citing works

AMPK modulates Hippo pathway activity to regulate energy homeostasis

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Treatment-Induced Tumor Dormancy through YAP-Mediated Transcriptional Reprogramming of the Apoptotic Pathway

Kurppa, K. J., Liu, Y., To, C., Zhang, T., Fan, M., Vajdi, A., Knelson, E. H., Xie, Y., Lim, K., Cejas, P., et al. (2020) · Cancer Cell · doi:10.1016/j.ccell.2019.12.006 · Cited by 475 · see citing works

YAP mediates crosstalk between the Hippo and PI(3)K–TOR pathways by suppressing PTEN via miR-29

Tumaneng, K., Schlegelmilch, K., Russell, R. C., Yimlamai, D., Basnet, H., Mahadevan, N., Fitamant, J., Bardeesy, N., Camargo, F. D., & Guan, K.-L. (2012) · Nature Cell Biology · doi:10.1038/ncb2615 · Cited by 453 · see citing works

Role of YAP/TAZ in cell-matrix adhesion-mediated signalling and mechanotransduction

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Yes-associated protein (YAP) transcriptional coactivator functions in balancing growth and differentiation in skin

Zhang, H., Pasolli, H. A., & Fuchs, E. (2011) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1019603108 · Cited by 419 · see citing works

Aerobic glycolysis tunes YAP/TAZ transcriptional activity

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Taxol Resistance in Breast Cancer Cells Is Mediated by the Hippo Pathway Component TAZ and Its Downstream Transcriptional Targets<i>Cyr61</i>and<i>CTGF</i>

Lai, D., Ho, K. C., Hao, Y., & Yang, X. (2011) · Cancer Research · doi:10.1158/0008-5472.can-10-2711 · Cited by 416 · see citing works

Hepatocyte TAZ/WWTR1 Promotes Inflammation and Fibrosis in Nonalcoholic Steatohepatitis

Wang, X., Zheng, Z., Caviglia, J. M., Corey, K. E., Herfel, T. M., Cai, B., Masia, R., Chung, R. T., Lefkowitch, J. H., Schwabe, R. F., et al. (2016) · Cell Metabolism · doi:10.1016/j.cmet.2016.09.016 · Cited by 413 · see citing works

YAP1 Exerts Its Transcriptional Control via TEAD-Mediated Activation of Enhancers

Stein, C., Bardet, A. F., Roma, G., Bergling, S., Clay, I., Ruchti, A., Agarinis, C., Schmelzle, T., Bouwmeester, T., Schübeler, D., et al. (2015) · PLOS Genetics · doi:10.1371/journal.pgen.1005465 · Cited by 414 · see citing works

Cardiac-Specific YAP Activation Improves Cardiac Function and Survival in an Experimental Murine MI Model

Lin, Z., von Gise, A., Zhou, P., Gu, F., Ma, Q., Jiang, J., Yau, A. L., Buck, J. N., Gouin, K. A., van Gorp, P. R. R., et al. (2014) · Circulation Research · doi:10.1161/circresaha.115.303632 · Cited by 403 · see citing works

Hippo Pathway-independent Restriction of TAZ and YAP by Angiomotin

Chan, S. W., Lim, C. J., Chong, Y. F., Pobbati, A. V., Huang, C., & Hong, W. (2011) · Journal of Biological Chemistry · doi:10.1074/jbc.c110.212621 · Cited by 386 · see citing works

Control of cellular responses to mechanical cues through YAP/TAZ regulation

Dasgupta, I., & McCollum, D. (2019) · Journal of Biological Chemistry · doi:10.1074/jbc.rev119.007963 · Cited by 360 · see citing works

Downstream of Mutant KRAS, the Transcription Regulator YAP Is Essential for Neoplastic Progression to Pancreatic Ductal Adenocarcinoma

Zhang, W., Nandakumar, N., Shi, Y., Manzano, M., Smith, A., Graham, G., Gupta, S., Vietsch, E. E., Laughlin, S. Z., Wadhwa, M., et al. (2014) · Science Signaling · doi:10.1126/scisignal.2005049 · Cited by 360 · see citing works

Hippo Signaling Regulates Microprocessor and Links Cell-Density-Dependent miRNA Biogenesis to Cancer

Mori, M., Triboulet, R., Mohseni, M., Schlegelmilch, K., Shrestha, K., Camargo, F. D., & Gregory, R. I. (2014) · Cell · doi:10.1016/j.cell.2013.12.043 · Cited by 335 · see citing works

Yes-Associated Protein Up-regulates Jagged-1 and Activates the NOTCH Pathway in Human Hepatocellular Carcinoma

Tschaharganeh, D. F., Chen, X., Latzko, P., Malz, M., Gaida, M. M., Felix, K., Ladu, S., Singer, S., Pinna, F., Gretz, N., et al. (2013) · Gastroenterology · doi:10.1053/j.gastro.2013.02.009 · Cited by 326 · see citing works

Autopalmitoylation of TEAD proteins regulates transcriptional output of the Hippo pathway

Chan, P., Han, X., Zheng, B., DeRan, M., Yu, J., Jarugumilli, G. K., Deng, H., Pan, D., Luo, X., & Wu, X. (2016) · Nature Chemical Biology · doi:10.1038/nchembio.2036 · Cited by 313 · see citing works

A genetic screen identifies an LKB1–MARK signalling axis controlling the Hippo–YAP pathway

Mohseni, M., Sun, J., Lau, A., Curtis, S., Goldsmith, J., Fox, V. L., Wei, C., Frazier, M., Samson, O., Wong, K.-K., et al. (2014) · Nature Cell Biology · doi:10.1038/ncb2884 · Cited by 294 · see citing works

YAP Drives Growth by Controlling Transcriptional Pause Release from Dynamic Enhancers

Galli, G. G., Carrara, M., Yuan, W.-C., Valdes-Quezada, C., Gurung, B., Pepe-Mooney, B., Zhang, T., Geeven, G., Gray, N. S., de Laat, W., et al. (2015) · Molecular Cell · doi:10.1016/j.molcel.2015.09.001 · Cited by 290 · see citing works

Characterization of Hippo Pathway Components by Gene Inactivation

Plouffe, S. W., Meng, Z., Lin, K. C., Lin, B., Hong, A. W., Chun, J. V., & Guan, K.-L. (2016) · Molecular Cell · doi:10.1016/j.molcel.2016.10.034 · Cited by 275 · see citing works

Regulation of TEAD Transcription Factors in Cancer Biology

Huh, H., Kim, D., Jeong, H.-S., & Park, H. (2019) · Cells · doi:10.3390/cells8060600 · Cited by 259 · see citing works

YAP-Induced PD-L1 Expression Drives Immune Evasion in BRAFi-Resistant Melanoma

Kim, M. H., Kim, C. G., Kim, S.-K., Shin, S. J., Choe, E. A., Park, S.-H., Shin, E.-C., & Kim, J. (2018) · Cancer Immunology Research · doi:10.1158/2326-6066.cir-17-0320 · Cited by 241 · see citing works

The Rho kinases: critical mediators of multiple profibrotic processes and rational targets for new therapies for pulmonary fibrosis

Knipe, R. S., Tager, A. M., & Liao, J. K. (2015) · Pharmacological Reviews · doi:10.1124/pr.114.009381 · Cited by 233 · see citing works

A Platform of Synthetic Lethal Gene Interaction Networks Reveals that the GNAQ Uveal Melanoma Oncogene Controls the Hippo Pathway through FAK

Feng, X., Arang, N., Rigiracciolo, D. C., Lee, J. S., Yeerna, H., Wang, Z., Lubrano, S., Kishore, A., Pachter, J. A., König, G. M., et al. (2019) · Cancer Cell · doi:10.1016/j.ccell.2019.01.009 · Cited by 237 · see citing works

Estrogen regulates Hippo signaling via GPER in breast cancer

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TGF-β Synergizes with Defects in the Hippo Pathway to Stimulate Human Malignant Mesothelioma Growth

Fujii, M., Toyoda, T., Nakanishi, H., Yatabe, Y., Sato, A., Matsudaira, Y., Ito, H., Murakami, H., Kondo, Y., Kondo, E., et al. (2012) · Journal of Experimental Medicine · doi:10.1084/jem.20111653 · Cited by 224 · see citing works

Mutual dependence of the MRTF–SRF and YAP–TEAD pathways in cancer-associated fibroblasts is indirect and mediated by cytoskeletal dynamics

Foster, C. T., Gualdrini, F., & Treisman, R. (2017) · Genes &amp; Development · doi:10.1101/gad.304501.117 · Cited by 202 · see citing works

The Hippo pathway effectors YAP and TAZ promote cell growth by modulating amino acid signaling to mTORC1

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Cholesterol Stabilizes TAZ in Hepatocytes to Promote Experimental Non-alcoholic Steatohepatitis

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Regulation of YAP by mTOR and autophagy reveals a therapeutic target of tuberous sclerosis complex

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PTPN14 is required for the density-dependent control of YAP1

Wang, W., Huang, J., Wang, X., Yuan, J., Li, X., Feng, L., Park, J.-I., & Chen, J. (2012) · Genes &amp; Development · doi:10.1101/gad.192955.112 · Cited by 195 · see citing works

The Hippo pathway member Yap plays a key role in influencing fate decisions in muscle satellite cells

Judson, R. N., Tremblay, A. M., Knopp, P., White, R. B., Urcia, R., De Bari, C., Zammit, P. S., Camargo, F. D., & Wackerhage, H. (2012) · Journal of Cell Science · doi:10.1242/jcs.109546 · Cited by 190 · see citing works

KIBRA Regulates Hippo Signaling Activity via Interactions with Large Tumor Suppressor Kinases

Xiao, L., Chen, Y., Ji, M., & Dong, J. (2011) · Journal of Biological Chemistry · doi:10.1074/jbc.m110.173468 · Cited by 190 · see citing works

dMyc Functions Downstream of Yorkie to Promote the Supercompetitive Behavior of Hippo Pathway Mutant Cells

Ziosi, M., Baena-López, L. A., Grifoni, D., Froldi, F., Pession, A., Garoia, F., Trotta, V., Bellosta, P., Cavicchi, S., & Pession, A. (2010) · PLoS Genetics · doi:10.1371/journal.pgen.1001140 · Cited by 184 · see citing works

αE-catenin inhibits a Src–YAP1 oncogenic module that couples tyrosine kinases and the effector of Hippo signaling pathway

Li, P., Silvis, M. R., Honaker, Y., Lien, W.-H., Arron, S. T., & Vasioukhin, V. (2016) · Genes &amp; Development · doi:10.1101/gad.274951.115 · Cited by 180 · see citing works

FAK controls the mechanical activation of YAP, a transcriptional regulator required for durotaxis

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YAP, TAZ, and Yorkie: a conserved family of signal-responsive transcriptional coregulators in animal development and human diseaseThis paper is one of a selection of papers published in this Special Issue, entitled CSBMCB’s 51st Annual Meeting – Epigenetics and Chromatin Dynamics, and has undergone the Journal’s usual peer review process.

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Genetic Control of Programmed Cell Death During Animal Development

Conradt, B. (2009) · Annual Review of Genetics · doi:10.1146/annurev.genet.42.110807.091533 · Cited by 173 · see citing works

Assembly and activation of the Hippo signalome by FAT1 tumor suppressor

Martin, D., Degese, M. S., Vitale-Cross, L., Iglesias-Bartolome, R., Valera, J. L. C., Wang, Z., Feng, X., Yeerna, H., Vadmal, V., Moroishi, T., et al. (2018) · Nature Communications · doi:10.1038/s41467-018-04590-1 · Cited by 174 · see citing works

Yap/Taz deletion in Gli(+) cell-derived myofibroblasts attenuates fibrosis

Liang, M., Yu, M., Xia, R., Song, K., Wang, J., Luo, J., Chen, G., & Cheng, J. (2017) · Journal of the American Society of Nephrology · doi:10.1681/asn.2015121354 · Cited by 169 · see citing works

The Hippo pathway effector YAP is a critical regulator of skeletal muscle fibre size

Watt, K. I., Turner, B. J., Hagg, A., Zhang, X., Davey, J. R., Qian, H., Beyer, C., Winbanks, C. E., Harvey, K. F., & Gregorevic, P. (2015) · Nature Communications · doi:10.1038/ncomms7048 · Cited by 164 · see citing works

Scribble participates in Hippo signaling and is required for normal zebrafish pronephros development

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Induction of Chromosome Instability by Activation of Yes-Associated Protein and Forkhead Box M1 in Liver Cancer

Weiler, S. M. E., Pinna, F., Wolf, T., Lutz, T., Geldiyev, A., Sticht, C., Knaub, M., Thomann, S., Bissinger, M., Wan, S., et al. (2017) · Gastroenterology · doi:10.1053/j.gastro.2017.02.018 · Cited by 155 · see citing works

Cdc42EP3/BORG2 and Septin Network Enables Mechano-transduction and the Emergence of Cancer-Associated Fibroblasts

Calvo, F., Ranftl, R., Hooper, S., Farrugia, A. J., Moeendarbary, E., Bruckbauer, A., Batista, F., Charras, G., & Sahai, E. (2015) · Cell Reports · doi:10.1016/j.celrep.2015.11.052 · Cited by 142 · see citing works

Therapeutic targeting of TEAD transcription factors in cancer

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YAP1/TAZ-TEAD transcriptional networks maintain skin homeostasis by regulating cell proliferation and limiting KLF4 activity

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YAP-Mediated Mechanotransduction in Skeletal Muscle

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Alveolar rhabdomyosarcoma–associated PAX3-FOXO1 promotes tumorigenesis via Hippo pathway suppression

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STAT3-YAP/TAZ signaling in endothelial cells promotes tumor angiogenesis

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Yes‐Associated Protein is up‐regulated by mechanical overload and is sufficient to induce skeletal muscle hypertrophy

Goodman, C. A., Dietz, J. M., Jacobs, B. L., McNally, R. M., You, J.-S., & Hornberger, T. A. (2015) · FEBS Letters · doi:10.1016/j.febslet.2015.04.047 · Cited by 121 · see citing works

Opposing activities of the Ras and Hippo pathways converge on regulation of YAP protein turnover

Hong, X., Nguyen, H. T., Chen, Q., Zhang, R., Hagman, Z., Voorhoeve, P. M., & Cohen, S. M. (2014) · The EMBO Journal · doi:10.15252/embj.201489385 · Cited by 121 · see citing works

MRTF potentiates TEAD‐YAP transcriptional activity causing metastasis

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Genome-Wide CRISPR Screens Identify Multiple Synthetic Lethal Targets That Enhance KRASG12C Inhibitor Efficacy

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Deregulation of the Hippo pathway in soft-tissue sarcoma promotes FOXM1 expression and tumorigenesis

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Intersection of Hippo/YAP and Wnt/&amp;beta;-catenin signaling pathways

Konsavage, W. M., & Yochum, G. S. (2013) · Acta Biochimica et Biophysica Sinica · doi:10.1093/abbs/gms084 · Cited by 94 · see citing works

The Hippo signal transduction network in skeletal and cardiac muscle

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Novel insights from a multiomics dissection of the Hayflick limit

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TEAD Inhibition Overcomes YAP1/TAZ-Driven Primary and Acquired Resistance to KRASG12C Inhibitors

Edwards, A. C., Stalnecker, C. A., Jean Morales, A., Taylor, K. E., Klomp, J. E., Klomp, J. A., Waters, A. M., Sudhakar, N., Hallin, J., Tang, T. T., et al. (2023) · Cancer Research · doi:10.1158/0008-5472.can-23-2994 · Cited by 91 · see citing works

PTPN14 Forms a Complex with Kibra and LATS1 Proteins and Negatively Regulates the YAP Oncogenic Function

Wilson, K. E., Li, Y.-W., Yang, N., Shen, H., Orillion, A. R., & Zhang, J. (2014) · Journal of Biological Chemistry · doi:10.1074/jbc.m113.534701 · Cited by 92 · see citing works

IGF2BP2 promotes the progression of colorectal cancer through a YAP‐dependent mechanism

Cui, J., Tian, J., Wang, W., He, T., Li, X., Gu, C., Wang, L., Wu, J., & Shang, A. (2021) · Cancer Science · doi:10.1111/cas.15083 · Cited by 90 · see citing works

Endothelial YAP/TAZ Signaling in Angiogenesis and Tumor Vasculature

Hooglugt, A., van der Stoel, M. M., Boon, R. A., & Huveneers, S. (2021) · Frontiers in Oncology · doi:10.3389/fonc.2020.612802 · Cited by 82 · see citing works

LKB1 tumor suppressor regulates AMP kinase/mTOR-independent cell growth and proliferation via the phosphorylation of Yap

Nguyen, H. B., Babcock, J. T., Wells, C. D., & Quilliam, L. A. (2013) · Oncogene · doi:10.1038/onc.2012.431 · Cited by 84 · see citing works

The alteration of Hippo/YAP signaling in the development of hypertrophic cardiomyopathy

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Localized EMT reprograms glial progenitors to promote spinal cord repair

Klatt Shaw, D., Saraswathy, V. M., Zhou, L., McAdow, A. R., Burris, B., Butka, E., Morris, S. A., Dietmann, S., & Mokalled, M. H. (2021) · Developmental Cell · doi:10.1016/j.devcel.2021.01.017 · Cited by 70 · see citing works

Epithelial splicing regulatory protein 2–mediated alternative splicing reprograms hepatocytes in severe alcoholic hepatitis

Hyun, J., Sun, Z., Ahmadi, A. R., Bangru, S., Chembazhi, U. V., Du, K., Chen, T., Tsukamoto, H., Rusyn, I., Kalsotra, A., et al. (2020) · Journal of Clinical Investigation · doi:10.1172/jci132691 · Cited by 76 · see citing works

Screening for YAP inhibitors identifies statins as modulators of fibrosis

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The Hippo pathway modulates resistance to BET proteins inhibitors in lung cancer cells

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Lats2 Modulates Adipocyte Proliferation and Differentiation via Hippo Signaling

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Covalent disruptor of YAP-TEAD association suppresses defective Hippo signaling

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Loss of DLG5 promotes breast cancer malignancy by inhibiting the Hippo signaling pathway

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Label-free quantitative proteomic analysis of the YAP/TAZ interactome

Kohli, P., Bartram, M. P., Habbig, S., Pahmeyer, C., Lamkemeyer, T., Benzing, T., Schermer, B., & Rinschen, M. M. (2014) · American Journal of Physiology-Cell Physiology · doi:10.1152/ajpcell.00339.2013 · Cited by 61 · see citing works

Planarian <i>yorkie/YAP</i> functions to integrate adult stem cell proliferation, organ homeostasis and maintenance of axial patterning

Lin, A. Y. T., & Pearson, B. J. (2014) · Development · doi:10.1242/dev.101915 · Cited by 57 · see citing works

Convergent Signaling in the Regulation of Connective Tissue Growth Factor in Malignant Mesothelioma: TGFβ Signaling and Defects in the Hippo Signaling Cascade

Fujii, M., Nakanishi, H., Toyoda, T., Tanaka, I., Kondo, Y., Osada, H., & Sekido, Y. (2012) · Cell Cycle · doi:10.4161/cc.21397 · Cited by 53 · see citing works

Harnessing Hippo in the heart: Hippo/Yap signaling and applications to heart regeneration and rejuvenation

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Vascular smooth muscle–specific YAP/TAZ deletion triggers aneurysm development in mouse aorta

Arévalo Martínez, M., Ritsvall, O., Bastrup, J. A., Celik, S., Jakobsson, G., Daoud, F., Winqvist, C., Aspberg, A., Rippe, C., Maegdefessel, L., et al. (2023) · JCI Insight · doi:10.1172/jci.insight.170845 · Cited by 51 · see citing works

The Hippo signal transduction network for exercise physiologists

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Transforming Growth Factor Beta Promotes Inflammation and Tumorigenesis in Smad4-Deficient Intestinal Epithelium in a YAP-Dependent Manner

Liu, L., Wang, Y., Yu, S., Liu, H., Li, Y., Hua, S., & Chen, Y. (2023) · Advanced Science · doi:10.1002/advs.202300708 · Cited by 45 · see citing works

LATS1 K751 acetylation blocks activation of Hippo signalling and switches LATS1 from a tumor suppressor to an oncoprotein

Yang, S., Xu, W., Liu, C., Jin, J., Li, X., Jiang, Y., Zhang, L., Meng, X., Zhan, J., & Zhang, H. (2022) · Science China Life Sciences · doi:10.1007/s11427-020-1914-3 · Cited by 24 · see citing works

HMG-CoA Reductase Inhibitor Statins Activate the Transcriptional Activity of p53 by Regulating the Expression of TAZ

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Therapy-Induced Transdifferentiation Promotes Glioma Growth Independent of EGFR Signaling

Oh, H., Hwang, I., Jang, J.-Y., Wu, L., Cao, D., Yao, J., Ying, H., Li, J. Y., Yao, Y., Hu, B., et al. (2021) · Cancer Research · doi:10.1158/0008-5472.can-20-1810 · Cited by 11 · see citing works

Expression of connective tissue growth factor in tumor tissues is an independent predictor of poor prognosis in patients with gastric cancer

Luying, Liu, Yanchun, et al. (2008) · Acta Scientiarum Naturalium Universitatis Sunyatseni

Resolution of experimental liver fibrosis in mice by targeted delivery of connective tissue growth factor siRNA

Brigstock, D. R., & Lawrencia, C. (2009) · The FASEB Journal · doi:10.1096/fasebj.23.1_supplement.117.5

Effect of compound Biejia Ruangan tablet on expressions of connective tissue growth factor mRNA and protein in kidney tissue of rats with adriamycin-induced nephropathy

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The expression and significance of renal connective tissue growth factor in lupus nephritis

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Defining the role of hif-1 ? And ctgf in fibrosis - biomed 2009.

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