mTOR regulates MAPKAPK2 translation to control the senescence-associated secretory phenotype

Herranz, Nicolás, Gallage, Suchira, Mellone, Massimiliano, Wuestefeld, Torsten, Klotz, Sabrina, Hanley, Christopher J., Raguz, Selina, Acosta, Juan Carlos, Innes, Andrew J., Banito, Ana, Georgilis, Athena, Montoya, Alex, Wolter, Katharina, Dharmalingam, Gopuraja, Faull, Peter, Carroll, Thomas, Martínez-Barbera, Juan Pedro, Cutillas, Pedro, Reisinger, Florian, Heikenwalder, Mathias, Miller, Richard A., Withers, Dominic, Zender, Lars, Thomas, Gareth J., Gil, Jesús·2015·Nature Cell Biology

DOI 10.1038/ncb3225

Cited by (799)

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Additional file 2 of The landscape of human tissue and cell type specific expression and co-regulation of senescence genes
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Additional file 1 of The landscape of human tissue and cell type specific expression and co-regulation of senescence genes
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Additional file 1 of MicroRNA-377-3p exacerbates chronic obstructive pulmonary disease through suppressing ZFP36L1 expression and inducing lung fibroblast senescence
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Additional file 4 of MicroRNA-377-3p exacerbates chronic obstructive pulmonary disease through suppressing ZFP36L1 expression and inducing lung fibroblast senescence
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Additional file 1 of Unveiling the molecular landscape of cognitive aging: insights from polygenic risk scores, DNA methylation, and gene expression
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Additional file 5 of Unveiling the molecular landscape of cognitive aging: insights from polygenic risk scores, DNA methylation, and gene expression
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Additional file 4 of mTOR inhibition abrogates human mammary stem cells and early breast cancer progression markers
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Additional file 7 of mTOR inhibition abrogates human mammary stem cells and early breast cancer progression markers
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Additional file 8 of Unveiling the molecular landscape of cognitive aging: insights from polygenic risk scores, DNA methylation, and gene expression
Sonya Carvalho Neto, Andreia Reis, Pinheiro, Miguel, Margarida Ferreira, Vasco Neves, Teresa Costa Castanho, Nadine Correia Santos, Rodrigues, Ana João, Sousa, Nuno, Manuel A. S. Santos et al. · 2024 · Figshare
Additional file 7 of Unveiling the molecular landscape of cognitive aging: insights from polygenic risk scores, DNA methylation, and gene expression
Sonya Carvalho Neto, Andreia Reis, Pinheiro, Miguel, Margarida Ferreira, Vasco Neves, Teresa Costa Castanho, Nadine Correia Santos, Rodrigues, Ana João, Sousa, Nuno, Manuel A. S. Santos et al. · 2024 · Figshare
Additional file 5 of mTOR inhibition abrogates human mammary stem cells and early breast cancer progression markers
Hakim Bouamar, Larry E. Broome, Lathrop, Kate Ida, Jatoi, Ismail, Brenner, Andrew Jacob, Alia N. Nazarullah, Karla M. Gorena, Michael Garcia, Chen, Yidong, Virginia Kaklamani et al. · 2023 · Figshare
Additional file 4 of Unveiling the molecular landscape of cognitive aging: insights from polygenic risk scores, DNA methylation, and gene expression
Sonya Carvalho Neto, Andreia Reis, Pinheiro, Miguel, Margarida Ferreira, Vasco Neves, Teresa Costa Castanho, Nadine Correia Santos, Rodrigues, Ana João, Sousa, Nuno, Manuel A. S. Santos et al. · 2024 · Figshare
Additional file 2 of mTOR inhibition abrogates human mammary stem cells and early breast cancer progression markers
Hakim Bouamar, Larry E. Broome, Lathrop, Kate Ida, Jatoi, Ismail, Brenner, Andrew Jacob, Alia N. Nazarullah, Karla M. Gorena, Michael Garcia, Chen, Yidong, Virginia Kaklamani et al. · 2023 · Figshare
Additional file 6 of Unveiling the molecular landscape of cognitive aging: insights from polygenic risk scores, DNA methylation, and gene expression
Sonya Carvalho Neto, Andreia Reis, Pinheiro, Miguel, Margarida Ferreira, Vasco Neves, Teresa Costa Castanho, Nadine Correia Santos, Rodrigues, Ana João, Sousa, Nuno, Manuel A. S. Santos et al. · 2024 · Figshare
Additional file 10 of Unveiling the molecular landscape of cognitive aging: insights from polygenic risk scores, DNA methylation, and gene expression
Sonya Carvalho Neto, Andreia Reis, Pinheiro, Miguel, Margarida Ferreira, Vasco Neves, Teresa Costa Castanho, Nadine Correia Santos, Rodrigues, Ana João, Sousa, Nuno, Manuel A. S. Santos et al. · 2024 · Figshare
Additional file 9 of Unveiling the molecular landscape of cognitive aging: insights from polygenic risk scores, DNA methylation, and gene expression
Sonya Carvalho Neto, Andreia Reis, Pinheiro, Miguel, Margarida Ferreira, Vasco Neves, Teresa Costa Castanho, Nadine Correia Santos, Rodrigues, Ana João, Sousa, Nuno, Manuel A. S. Santos et al. · 2024 · Figshare
Additional file 1 of Rapamycin promotes endothelial–mesenchymal transition during stress-induced premature senescence through the activation of autophagy
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Additional file 2 of Unveiling the molecular landscape of cognitive aging: insights from polygenic risk scores, DNA methylation, and gene expression
Sonya Carvalho Neto, Andreia Reis, Pinheiro, Miguel, Margarida Ferreira, Vasco Neves, Teresa Costa Castanho, Nadine Correia Santos, Rodrigues, Ana João, Sousa, Nuno, Manuel A. S. Santos et al. · 2024 · Figshare
Additional file 3 of MicroRNA-377-3p exacerbates chronic obstructive pulmonary disease through suppressing ZFP36L1 expression and inducing lung fibroblast senescence
Lu, Fang, Yao, Li-peng, Gao, Dan-dan, Tahereh Alinejad, Jiang, Xin-qing, Qi Wu, Zhai, Qiao-cheng, Liu, Ming, Zhu, Sheng-mei, Qian, Mao-xiang et al. · 2024 · Figshare
Additional file 3 of mTOR inhibition abrogates human mammary stem cells and early breast cancer progression markers
Hakim Bouamar, Larry E. Broome, Lathrop, Kate Ida, Jatoi, Ismail, Brenner, Andrew Jacob, Alia N. Nazarullah, Karla M. Gorena, Michael Garcia, Chen, Yidong, Virginia Kaklamani et al. · 2023 · Figshare
Additional file 2 of MicroRNA-377-3p exacerbates chronic obstructive pulmonary disease through suppressing ZFP36L1 expression and inducing lung fibroblast senescence
Lu, Fang, Yao, Li-peng, Gao, Dan-dan, Tahereh Alinejad, Jiang, Xin-qing, Qi Wu, Zhai, Qiao-cheng, Liu, Ming, Zhu, Sheng-mei, Qian, Mao-xiang et al. · 2024 · Figshare
Additional file 6 of mTOR inhibition abrogates human mammary stem cells and early breast cancer progression markers
Hakim Bouamar, Larry E. Broome, Lathrop, Kate Ida, Jatoi, Ismail, Brenner, Andrew Jacob, Alia N. Nazarullah, Karla M. Gorena, Michael Garcia, Chen, Yidong, Virginia Kaklamani et al. · 2024 · Figshare
Additional file 1 of mTOR inhibition abrogates human mammary stem cells and early breast cancer progression markers
Hakim Bouamar, Larry E. Broome, Lathrop, Kate Ida, Jatoi, Ismail, Brenner, Andrew Jacob, Alia N. Nazarullah, Karla M. Gorena, Michael Garcia, Chen, Yidong, Virginia Kaklamani et al. · 2023 · Figshare
Additional file 5 of MicroRNA-377-3p exacerbates chronic obstructive pulmonary disease through suppressing ZFP36L1 expression and inducing lung fibroblast senescence
Lu, Fang, Yao, Li-peng, Gao, Dan-dan, Tahereh Alinejad, Jiang, Xin-qing, Qi Wu, Qiaocheng Zhai, Liu, Ming, Zhu, Sheng-mei, Qian, Mao-xiang et al. · 2024 · Figshare
Additional file 3 of Unveiling the molecular landscape of cognitive aging: insights from polygenic risk scores, DNA methylation, and gene expression
Sonya Carvalho Neto, Andreia Reis, Pinheiro, Miguel, Margarida Ferreira, Vasco Neves, Teresa Costa Castanho, Nadine Correia Santos, Rodrigues, Ana João, Sousa, Nuno, Manuel A. S. Santos et al. · 2024 · Figshare
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