Regulation of p53 activity by its interaction with homeodomain-interacting protein kinase-2

Mdm2 promotes the rapid degradation of p53

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Regulation of p53 stability by Mdm2

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The mdm-2 oncogene product forms a complex with the p53 protein and inhibits p53-mediated transactivation

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DNA damage-induced phosphorylation of p53 alleviates inhibition by MDM2

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DNA damage activates p53 through a phosphorylation–acetylation cascade

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Peroxisome Proliferator-activated Receptor α Negatively Regulates the Vascular Inflammatory Gene Response by Negative Cross-talk with Transcription Factors NF-κB and AP-1

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The human homologs of checkpoint kinases Chk1 and Cds1 (Chk2) phosphorylate p53 at multiple DNA damage-inducible sites.

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p53 Sites Acetylated In Vitro by PCAF and p300 Are Acetylated In Vivo in Response to DNA Damage

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Blinded by the Light: The Growing Complexity of p53

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NRF2 and the Hallmarks of Cancer

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Post-translational modification of p53 in tumorigenesis

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DNA damage and the balance between survival and death in cancer biology

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The multiple mechanisms that regulate p53 activity and cell fate

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A complex barcode underlies the heterogeneous response of p53 to stress

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Various modes of cell death induced by DNA damage

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The Down syndrome-related protein kinase DYRK1A phosphorylates p27Kip1and Cyclin D1 and induces cell cycle exit and neuronal differentiation

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Another fork in the road—life or death decisions by the tumour suppressor p53

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Dyrk1A phosphorylates p53 and inhibits proliferation of embryonic neuronal cells

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Daxx Cooperates with the Axin/HIPK2/p53 Complex to Induce Cell Death

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The p53 response: Emerging levels of co-factor complexity

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Deciphering the acetylation code of p53 in transcription regulation and tumor suppression

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Insights into regulators of p53 acetylation

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TRIMming p53’s anticancer activity

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CDK4 inhibition diminishes p53 activation by MDM2 antagonists

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Tumor suppressor protein Pdcd4 interacts with Daxx and modulates the stability of Daxx and the Hipk2-dependent phosphorylation of p53 at serine 46

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DAZAP2 acts as specifier of the p53 response to DNA damage

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