A comprehensive 1000 Genomes–based genome-wide association meta-analysis of coronary artery disease

the CARDIoGRAMplusC4D Consortium·2015·Nature Genetics

DOI 10.1038/ng.3396

Cited by (1,004)

Items 201–300 of 1,004

Genome-wide association and multi-trait analyses characterize the common genetic architecture of heart failure
Michael G. Levin, Noah L. Tsao, Pankhuri Singhal, Chang Liu, Ha My T. Vy, Ishan Paranjpe, Joshua Backman, Tiffany R. Bellomo, William P. Bone, Kiran J. Biddinger et al. · 2022 · Nature Communications
Erythrogene: a database for in-depth analysis of the extensive variation in 36 blood group systems in the 1000 Genomes Project
Mattias Möller, Magnus Jöud, Jill R. Storry, Martin L. Olsson · 2016 · Blood Advances
Genome-wide association studies and Mendelian randomization analyses for leisure sedentary behaviours
Yordi J. van de Vegte, M. Abdullah Said, Michiel Rienstra, Pim van der Harst, Niek Verweij · 2020 · Nature Communications
Predictive Utility of Polygenic Risk Scores for Coronary Heart Disease in Three Major Racial and Ethnic Groups
Ozan Dikilitas, Daniel J. Schaid, Matthew Kosel, Robert J. Carroll, Christopher G. Chute, Joshua C. Denny, Alex Fedotov, QiPing Feng, Hakon H. Hakonarson, Gail Pairitz Jarvik et al. · 2020 · The American Journal of Human Genetics
A critique of life history approaches to human trait covariation
Brendan P. Zietsch, Morgan J. Sidari · 2019 · Evolution and Human Behavior
HDAC9 is implicated in atherosclerotic aortic calcification and affects vascular smooth muscle cell phenotype
Rajeev Kumar Malhotra, Andreas C. Mauer, Christian Lacks Lino Cardenas, Xiuqing Guo, Jie Yao, Xiaoling Zhang, Florian Wunderer, Albert V. Smith, Quenna Wong, Sonali Pechlivanis et al. · 2019 · Nature Genetics
Genetic predisposition to smoking in relation to 14 cardiovascular diseases
Susanna C. Larsson, Amy M. Mason, Magnus Bäck, Derek M. Klarin, Scott M. Damrauer, Million Veteran Program, Karl Michaëlsson, Stephen Burgess · 2020 · European Heart Journal
Polygenic Scores to Assess Atherosclerotic Cardiovascular Disease Risk
Krishna G. Aragam, Pradeep Natarajan · 2020 · Circulation Research
Significant sparse polygenic risk scores across 813 traits in UK Biobank
Yosuke Tanigawa, Junyang Qian, Guhan Ram Venkataraman, Johanne Marie Justesen, Ruilin Li, Robert John Tibshirani, Trevor J. Hastie, Manuel A. Rivas · 2022 · PLoS Genetics
Integrative functional genomics identifies regulatory mechanisms at coronary artery disease loci
Clint L. Miller, Milos Pjanic, Ting Wang, Trieu Nguyen, Ariella T. Cohain, Jonathan D. Lee, Ljubica Perisic Matic, Ulf Hedin, Ramendra Krishna Kundu, Deshna Majmudar et al. · 2016 · Nature Communications
Expression quantitative trait loci in the developing human brain and their enrichment in neuropsychiatric disorders
Heath O’Brien, Eilis J. Hannon, Matthew Hill, Carolina Toste, Matthew J. Robertson, Joanne Morgan, Gemma M. McLaughlin, Cathryn M. Lewis, Leonard C. Schalkwyk, Lynsey S. Hall et al. · 2018 · Genome biology
Trans-ethnic kidney function association study reveals putative causal genes and effects on kidney-specific disease aetiologies
Andrew P. Morris, Thu H Le, Hao Wu, Artur Akbarov, Peter J. van der Most, Gibran Hemani, George Davey Smith, Anubha Mahajan, Kyle J. Gaulton, Girish N. Nadkarni et al. · 2018 · Nature Communications
Low-Grade Chronic Inflammation: a Shared Mechanism for Chronic Diseases
Mariana Cifuentes, Hugo Verdejo, Pablo Castro, Alejandro H. Corvalán, Catterina Ferreccio R, Andrew F. G. Quest, Marcelo Javier Kogan, Sergio Lavandero · 2024 · Physiology
A promoter interaction map for cardiovascular disease genetics
Montefiori, Lindsey E, Sobreira, Debora R, Sakabe, Noboru J, Aneas, Ivy, Joslin, Amelia C, Hansen, Grace T, Bozek, Grazyna, Moskowitz, Ivan P, McNally, Elizabeth M, Nóbrega, Marcelo A · 2018 · eLife
Cholesteryl ester transfer protein (CETP) as a drug target for cardiovascular disease
Amand Floriaan Schmidt, Nicholas B. Hunt, María Gordillo‐Marañón, Pimphen Charoen, Fotios Drenos, Juan Pablo Casas, Mika Kivimaki B, Debbie A. Lawlor, Claudia Giambartolomei, Olia Papacosta et al. · 2021 · Nature Communications
Genomics in Personalized Nutrition: Can You “Eat for Your Genes”?
Veronica Anne Mullins, William Bresette, Laurel M. Johnstone, Brian Hallmark, Floyd H. Chilton · 2020 · Nutrients
Genetic architecture of host proteins involved in SARS-CoV-2 infection
Maik Pietzner, Eleanor Wheeler, Julia Carrasco-Zanini, Johannes Raffler, Nicola D. Kerrison, Erin Oerton, Victoria P.W. Auyeung, Jian’an Luan, Chris Finan, Juan Pablo Casas et al. · 2020 · Nature Communications
Plasma proteins and onset of type 2 diabetes and diabetic complications: Proteome-wide Mendelian randomization and colocalization analyses
Shuai Yuan, Fengzhe Xu, Xue Li, Jie Chen, Jie Zheng, Christos Socrates Mantzoros, Susanna C. Larsson · 2023 · Cell Reports Medicine
Correction: Shared mechanisms between coronary heart disease and depression: findings from a large UK general population-based cohort
Golam Mohammed Khandaker, Verena Zuber, Jessica M. B. Rees, Lívia A. Carvalho, Amy M. Mason, Christopher N. Foley, Apostolos Gkatzionis, Peter Brian Jones, Stephen Burgess · 2020 · Molecular Psychiatry
LPA Gene, Ethnicity, and Cardiovascular Events
Sang Rok Lee, Anand Prasad, Yun Seok Choi, Chao Xing, Paul Clopton, Joseph Lee Witztum, Sotirios Tsimikas · 2016 · Circulation
Effects of tumour necrosis factor on cardiovascular disease and cancer: A two-sample Mendelian randomization study
Shuai Yuan, Paul Carter, Maria Bruzelius, Mathew Kurian Vithayathil, Siddhartha Kar, Amy M. Mason, Ang Lin, Stephen Burgess, Susanna C. Larsson · 2020 · EBioMedicine
Genetic Architecture of Abdominal Aortic Aneurysm in the Million Veteran Program
Derek M. Klarin, Shefali S. Verma, Renae Judy, Ozan Dikilitas, Brooke N. Wolford, Ishan Paranjpe, Michael G. Levin, Cuiping Pan, Catherine Tcheandjieu, Joshua Michael Spin et al. · 2020 · Circulation
Cell-specific histone modification maps in the human frontal lobe link schizophrenia risk to the neuronal epigenome
Girdhar, Kiran, Hoffman, Gabriel E., Jiang, Yan, Brown, Leanne, Kundakovic, Marija, Hauberg, Mads E., Francoeur, Nancy J., Wang, Ying-chih, Shah, Hardik, Kavanagh, David H. et al. · 2018 · Nature Neuroscience
Limitations of Contemporary Guidelines for Managing Patients at High Genetic Risk of Coronary Artery Disease
Krishna G. Aragam, Amanda L. Dobbyn, Renae Judy, Mark D. Chaffin, Kumardeep Chaudhary, George Hindy, Andrew Cagan, Phoebe Finneran, Lu-Chen C Weng, Ruth J. F. Loos et al. · 2020 · Journal of the American College of Cardiology
Evaluation of bi-directional causal association between depression and cardiovascular diseases: a Mendelian randomization study
Gloria Hoi‐Yee Li, Ching‐Lung Cheung, Albert Kar-Kin Chung, Bernard M.Y. Cheung, Ian Chi Kei Wong, Marcella Lei-Yee Fok, Philip Chun-Ming Au, Pak Chung Sham · 2020 · Psychological Medicine
MR-Base: a platform for systematic causal inference across the phenome using billions of genetic associations
Gibran Hemani, Jie Zheng, Kaitlin Hazel Wade, Charles Laurin, Benjamin Elsworth, Stephen Burgess, Jack Bowden, Ryan Langdon, Vanessa Y. Tan, James Yarmolinsky et al. · 2016 · bioRxiv (Cold Spring Harbor Laboratory)
Genetic association of lipids and lipid-lowering drug target genes with non-alcoholic fatty liver disease
Ziang Li, Bin Zhang, Qing‐Rong Liu, Zhihang Tao, Lu Ding, Bo Guo, Erli Zhang, Haitong Zhang, Zhen Meng, Shuai Guo et al. · 2023 · EBioMedicine
Clinical laboratory test-wide association scan of polygenic scores identifies biomarkers of complex disease
Jessica Kiri Dennis, Julia Sealock, Péter Straub, Young A Lee, Donald Hucks, Ky’Era V. Actkins, Annika B. Faucon, Yen‐Chen Anne Feng, Tian Ge, Slavina B. Goleva et al. · 2021 · Genome Medicine
PRSet: Pathway-based polygenic risk score analyses and software
Shing Wan Choi, Judit García‐González, Yunfeng Ruan, Hei Man Wu, Christian Porras, Jessica Johnson, Clive J. Hoggart, Paul F. O’Reilly · 2023 · PLoS Genetics
A transcriptome-wide association study identifies PALMD as a susceptibility gene for calcific aortic valve stenosis
Thériault, Sébastien, Gaudreault, Nathalie, Lamontagne, Maxime, Rosa, Mickael, Boulanger, Marie-Chloé, Messika-Zeitoun, David, Clavel, Marie-Annick, Capoulade, Romain, Dagenais, François, Pibarot, Philippe et al. · 2018 · Nature Communications
Assessing the causal association of glycine with risk of cardio-metabolic diseases
Laura B. L. Wittemans, Luca Andrea Lotta, Clare Oliver‐Williams, Isobel D. Stewart, Praveen Surendran, Savita Karthikeyan, Felix R. Day, Albert Koulman, Fumiaki Imamura, Lingyao Zeng et al. · 2019 · Nature Communications
Birthweight, Type 2 Diabetes Mellitus, and Cardiovascular Disease
Daniela Zanetti, Emmi Tikkanen, Stefan Gustafsson, James Rush Priest, Stephen Burgess, Erik Ingelsson · 2018 · Circulation Genomic and Precision Medicine
Causal Effect of Plasminogen Activator Inhibitor Type 1 on Coronary Heart Disease
Ci Song, Stephen Burgess, John D. Eicher, Christopher J. O’Donnell, Andrew D. Johnson, Jie Huang, Maria Sabater‐Lleal, Folkert Wouter Asselbergs, David‐Alexandre Trégouët, So‐Youn Shin et al. · 2017 · Journal of the American Heart Association
Evaluation of the causal effects between subjective wellbeing and cardiometabolic health: mendelian randomisation study
Wootton, Robyn E, Lawn, Rebecca B, Millard, Louise A C, Davies, Neil M, Taylor, Amy E, Munafò, Marcus R, Timpson, Nicholas J, Davis, Oliver S P, Davey Smith, George, Haworth, Claire M A · 2018 · BMJ
Debiased inverse-variance weighted estimator in two-sample summary-data Mendelian randomization
Ting Ye, Jun Shao, Hyunseung Kang · 2021 · The Annals of Statistics
Genome-wide association study and targeted metabolomics identifies sex-specific association of CPS1 with coronary artery disease
Hartiala, Jaana A., Wilson Tang, W. H., Wang, Zeneng, Crow, Amanda L., Stewart, Alexandre F. R., Roberts, Robert, McPherson, Ruth, Erdmann, Jeanette, Willenborg, Christina, Hazen, Stanley L. et al. · 2016 · Nature Communications
Life’s Essential 8, Genetic Susceptibility, and Incident Cardiovascular Disease: A Prospective Study
Xiang Li, Hao Ma, Xuan Wang, Han Feng, Lu Qi · 2023 · Arteriosclerosis Thrombosis and Vascular Biology
Large-scale genome-wide analysis identifies genetic variants associated with cardiac structure and function
Wild, Philipp S., Felix, Janine F., Schillert, Arne, Teumer, Alexander, Chen, Ming-Huei, Leening, Maarten J.G., Völker, Uwe, Großmann, Vera, Brody, Jennifer A., Irvin, Marguerite R. et al. · 2017 · Journal of Clinical Investigation
Re-analysis of public genetic data reveals a rare X-chromosomal variant associated with type 2 diabetes
Sílvia Bonàs‐Guarch, Marta Guindo-Martínez, Irene Miguel-Escalada, Niels Grarup, David Sebastián, Elias Rodríguez-Fos, Friman Sánchez, Mercè Planas-Fèlix, Paula Cortés-Sánchez, Santiago González et al. · 2018 · Nature Communications
Association of Genetic Variation With Cirrhosis: A Multi-Trait Genome-Wide Association and Gene–Environment Interaction Study
Connor A. Emdin, Mary Haas, Veeral H. Ajmera, Tracey G. Simon, Julian R. Homburger, Cynthia L. Neben, Lan Jiang, Wei‐Qi Wei, QiPing Feng, Alicia Yiran Zhou et al. · 2020 · Gastroenterology
Association of habitual glucosamine use with risk of cardiovascular disease: prospective study in UK Biobank
Hao Ma, Xiang Li, Dianjianyi Sun, Tao Zhou, Sylvia H. Ley, Jeanette Gustat, Yoriko Heianza, Lu Qi · 2019 · BMJ
Genetic dysregulation of endothelin-1 is implicated in coronary microvascular dysfunction
Thomas Joseph Ford, David S. Corcoran, Sandosh Padmanabhan, Alisha Aman, Paul Rocchiccioli, Richard Good, Margaret B. McEntegart, Janet J. Maguire, Stuart Watkins, Hany Eteiba et al. · 2019 · European Heart Journal
Diet-Derived Circulating Antioxidants and Risk of Coronary Heart Disease
Jiao Min Luo, Saskia le Cessie, Diana van Heemst, Raymond Noordam · 2021 · Journal of the American College of Cardiology
Mendelian Randomization Study of PCSK9 and HMG-CoA Reductase Inhibition and Cognitive Function
Rosoff, Daniel B., Bell, Andrew S., Jung, Jeesun, Wagner, Josephin, Mavromatis, Lucas A., Lohoff, Falk W. · 2022 · Journal of the American College of Cardiology
Major review: Exfoliation syndrome; advances in disease genetics, molecular biology, and epidemiology
Inas F. Aboobakar, William M. Johnson, William Daniel Stamer, Michael A. Hauser, R. Rand Allingham · 2016 · Experimental Eye Research
Unveiling the Role of the Most Impactful Cardiovascular Risk Locus through Haplotype Editing
Valentina Lo Sardo, Pavel Chubukov, William Cashman Ferguson, Aditya Kumar, Evan L. Teng, Michael Duran, Lei Zhang, Gregory J. Cost, Adam Jeffrey Engler, Fyodor D. Urnov et al. · 2018 · Cell
Association of genetically predicted testosterone with thromboembolism, heart failure, and myocardial infarction: mendelian randomisation study in UK Biobank
Shan Luo, Shiu Lun Au Yeung, Jie V. Zhao, Stephen Burgess, Catherine Mary Schooling · 2019 · BMJ
Genome-wide analysis yields new loci associating with aortic valve stenosis
Helgadottir, Anna, Thorleifsson, Gudmar, Gretarsdottir, Solveig, Stefansson, Olafur A., Tragante, Vinicius, Thorolfsdottir, Rosa B., Jonsdottir, Ingileif, Bjornsson, Thorsteinn, Steinthorsdottir, Valgerdur, Verweij, Niek et al. · 2018 · Nature Communications
Genome-wide association analysis of self-reported events in 6135 individuals and 252 827 controls identifies 8 loci associated with thrombosis
David A. Hinds, Alfonso Buil, Daniel Ziemek, Ángel Martínez-Pérez, Rainer Malik, Lasse Folkersen, Marine Germain, Anders Mälarstig, Andrew Anand Brown, José Manuel Soria et al. · 2016 · Human Molecular Genetics
Multi-ancestry genome-wide gene–smoking interaction study of 387,272 individuals identifies new loci associated with serum lipids
Amy R. Bentley, Understanding Society Scientific Group, Lifelines Cohort, Yun J. Sung, Michael R. Brown, Thomas W. Winkler, Aldi T. Kraja, Ιωάννα Ντάλλα, Karen Schwander, Daniel I. Chasman et al. · 2019 · Nature Genetics
Evaluation of Large-Scale Proteomics for Prediction of Cardiovascular Events
Hannes Helgason, Thjodbjorg Eiriksdottir, Magnus Orn Ulfarsson, Abhishek Choudhary, Sigrún H. Lund, Erna V. Ivarsdottir, Grímur Hjörleifsson Eldjárn, Guðmundur Einarsson, Egil Ferkingstad, Kristjan H. S. Moore et al. · 2023 · JAMA
TGFβ, smooth muscle cells and coronary artery disease: a review
Emma L. Low, Andrew Howard Baker, Angela C. Bradshaw · 2018 · Cellular Signalling
A mechanistic framework for cardiometabolic and coronary artery diseases
Simon Koplev, Marcus Michael Seldin, Katyayani Sukhavasi, Raili Ermel, Shichao Pang, Lingyao Zeng, Sean Bankier, Antonio Di Narzo, Haoxiang M. Cheng, Vamsidhar Meda et al. · 2022 · Nature Cardiovascular Research
Relationship between NAFLD and coronary artery disease: A Mendelian randomization study
Zhewen Ren, Pomme I. H. G. Simons, Anke Wesselius, Coen D.A. Stehouwer, Martijn C.G.J. Brouwers · 2022 · Hepatology
Coronary Atherosclerosis: Pathophysiologic Basis for Diagnosis and Management
Konstantinos Dean Boudoulas, Filippos K. Triposkiadis, Paraschos Geleris, Harisios K Boudoulas · 2016 · Progress in Cardiovascular Diseases
Endothelial adenosine A2a receptor-mediated glycolysis is essential for pathological retinal angiogenesis
Zhiping Liu, Siyuan Yan, Jiaojiao Wang, Yiming Xu, Yong Wang, Shuya Zhang, Xizhen Xu, Qiuhua Yang, Xianqiu Zeng, Yaqi Zhou et al. · 2017 · Nature Communications
Genetics Insights in the Relationship Between Type 2 Diabetes and Coronary Heart Disease
Mark O. Goodarzi, Jerome I. Rotter · 2020 · Circulation Research
Elevated Lipoprotein(a) and Risk of Atrial Fibrillation
Pedrum Mohammadi‐Shemirani, Michael Chong, Sukrit Narula, Nicolas Perrot, David Conen, Jason D. Roberts, Sébastien Thériault, Yohan Bossé, Matthew Bruce Lanktree, Marie Pigeyre et al. · 2022 · Journal of the American College of Cardiology
Childhood BMI and Adult Type 2 Diabetes, Coronary Artery Diseases, Chronic Kidney Disease, and Cardiometabolic Traits: A Mendelian Randomization Analysis
Tingting Geng, Caren E. Smith, Changwei Li, Tao Huang · 2018 · Diabetes Care
Expanding the genetic architecture of nicotine dependence and its shared genetics with multiple traits
Bryan C. Quach, Michael A. Bray, Nathan Gaddis, Mengzhen Liu, Teemu Palviainen, Camelia C. Minică, Stephanie M. Zellers, Richard Sherva, Fazil Alıev, Michael Nothnagel et al. · 2020 · Nature Communications
Genetic analysis in European ancestry individuals identifies 517 loci associated with liver enzymes
Raha Pazoki, Marijana Vujković, Joshua Elliott, Εvangelos Εvangelou, Dipender Gill, Mohsen Ghanbari, Peter J. van der Most, Rui Climaco Pinto, Matthias Wielscher, Matthias Farlik et al. · 2021 · Nature Communications
Evaluating the cardiovascular safety of sclerostin inhibition using evidence from meta-analysis of clinical trials and human genetics
Bovijn, Jonas, Krebs, Kristi, Chen, Chia-Yen, Boxall, Ruth, Censin, Jenny C., Ferreira, Teresa, Pulit, Sara L., Glastonbury, Craig A., Laber, Samantha, Millwood, Iona Y. et al. · 2020 · Science Translational Medicine
Phenotypic Consequences of a Genetic Predisposition to Enhanced Nitric Oxide Signaling
Connor A. Emdin, Amit V. Khera, Derek M. Klarin, Pradeep Natarajan, Seyedeh Maryam Zekavat, Akihiro Nomura, Mary E. Haas, Krishna G. Aragam, Diego Ardissino, James G. Wilson et al. · 2017 · Circulation
Lipoprotein(a): An independent, genetic, and causal factor for cardiovascular disease and acute myocardial infarction
Enas A. Enas, Basil Varkey, Thiruvinvamalai S. Dharmarajan, Guillaume Paré, Vinay Kumar Bahl · 2019 · Indian Heart Journal
Single-Cell Transcriptomic Atlas of Different Human Cardiac Arteries Identifies Cell Types Associated With Vascular Physiology
Zhan Hu, Wendao Liu, Xiumeng Hua, Xiao Chen, Yuan Chang, Yiqing Hu, Zhenyu Xu, Jiangping Song · 2021 · Arteriosclerosis Thrombosis and Vascular Biology
Abstract
Burgess, S · 2018 · Apollo (University of Cambridge)
Ideal cardiovascular health influences cardiovascular disease risk associated with high lipoprotein(a) levels and genotype: The EPIC-Norfolk prospective population study
Nicolas Perrot, Rutger Verbeek, Manjinder S. Sandhu, S. Matthijs Boekholdt, G. Kees Hovingh, Nicholas J. Wareham, Kay‐Tee Khaw, Benoît J. Arsenault · 2016 · Atherosclerosis
Interactions Between Enhanced Polygenic Risk Scores and Lifestyle for Cardiovascular Disease, Diabetes, and Lipid Levels
Yixuan Ye, Xi Dawn Chen, James Jisu Han, Wei Jiang, Pradeep Natarajan, Hongyu Zhao · 2021 · Circulation Genomic and Precision Medicine
Heart–brain interactions in cardiac and brain diseases: why sex matters
Alexia Rossi, Nidaa Mikaïl, Susan Bengs, Ahmed Haider, Valérie Treyer, Ronny R. Buechel, Susanne Wegener, Katrin Rauen, Ahmed A Tawakol, C. Noel Bairey Merz et al. · 2022 · European Heart Journal
Genetic Analysis of Venous Thromboembolism in UK Biobank Identifies the ZFPM2 Locus and Implicates Obesity as a Causal Risk Factor
Derek M. Klarin, Connor A. Emdin, Pradeep Natarajan, Mark Frederick Conrad, Sekar Kathiresan · 2017 · Circulation Cardiovascular Genetics
Multiomics Network Medicine Approaches to Precision Medicine and Therapeutics in Cardiovascular Diseases
Rui‐Sheng Wang, Bradley A. Maron, Joseph Loscalzo · 2023 · Arteriosclerosis Thrombosis and Vascular Biology
Dyslipidemia, inflammation, calcification, and adiposity in aortic stenosis: a genome-wide study
Yu Chen, Hao, Dina, Christian, Small, Aeron M, Shaffer, Christian M, Levinson, Rebecca T, Helgadóttir, Anna, Capoulade, Romain, Munter, Hans Markus, Martinsson, Andreas, Cairns, Benjamin J et al. · 2023 · European Heart Journal
Genetics: Implications for Prevention and Management of Coronary Artery Disease
Themistocles L. Assimes, Robert Roberts · 2016 · Journal of the American College of Cardiology
1000 Genomes-based meta-analysis identifies 10 novel loci for kidney function
Mathias Gorski, Peter J. van der Most, Alexander Teumer, Audrey Y. Chu, Man Li, Vladan Mijatovic, Ilja Maria Nolte, Massimiliano Cocca, Daniel Taliun, Felicia Gomez et al. · 2017 · Scientific Reports
Into the Wild: GWAS Exploration of Non-coding RNAs
Hector Giral, Ulf Landmesser, Adelheid Kratzer · 2018 · Frontiers in Cardiovascular Medicine
Multiancestry Genome-Wide Association Study of Lipid Levels Incorporating Gene-Alcohol Interactions
Paul S. de Vries, Michael R Brown, Amy R. Bentley, Yun J Sung, Thomas W. Winkler, Ιωάννα Ντάλλα, Karen Schwander, Aldi T. Kraja, Xiuqing Guo, Nora Franceschini et al. · 2019 · American Journal of Epidemiology
Polygenic risk score predicts prevalence of cardiovascular disease in patients with familial hypercholesterolemia
Paquette, Martine, Chong, Michael, Thériault, Sébastien, Dufour, Robert, Paré, Guillaume, Baass, Alexis · 2017 · Journal of Clinical Lipidology
Geographic Variation and Bias in the Polygenic Scores of Complex Diseases and Traits in Finland
Sini Kerminen, Alicia R. Martin, Jukka T. Koskela, Sanni Ruotsalainen, Aki Samuli Havulinna, Ida L. Surakka, Aarno V. Palotie, Markus Perola, Veikko V Salomaa, Mark J. Daly et al. · 2019 · The American Journal of Human Genetics
Receptor-Mediated ER Export of Lipoproteins Controls Lipid Homeostasis in Mice and Humans
Xiao Wang, Huimin Wang, Bolin Xu, Dong Huang, Chao Nie, Longjun Pu, Gregory J. M. Zajac, Han Yan, Jingru Zhao, Fangyuan Shi et al. · 2020 · Cell Metabolism
Genome-wide discovery of genetic loci that uncouple excess adiposity from its comorbidities
Lam Opal Huang, Alexander Rauch, Eugenia Mazzaferro, Michael H Preuss, Stefania Carobbio, Çiğdem Sevim Bayrak, Nathalie Chami, Zhe Wang, Ursula M. Schick, Nancy Y. Yang et al. · 2021 · Nature Metabolism
Genetic overlap of chronic obstructive pulmonary disease and cardiovascular disease-related traits: a large-scale genome-wide cross-trait analysis
Zhaozhong Zhu, Xiaofang Wang, Xihao Li, Yifei Lin, Sipeng Shen, Cong-Lin Liu, Brian D. Hobbs, Kohei Hasegawa, Liming Liang, H. Marike Boezen et al. · 2019 · Respiratory Research
C-Reactive Protein Levels and Risk of Cardiovascular Diseases: A Two-Sample Bidirectional Mendelian Randomization Study
Annapurna Kuppa, Himi Tripathi, Ahmed Al‐Darraji, Wadea M. Tarhuni, Ahmed Abdel‐Latif · 2023 · International Journal of Molecular Sciences
First international consensus on the diagnosis and management of fibromuscular dysplasia
Gornik, Heather L., Persu, Alexandre, Adlam, David, Aparicio, Lucas S., Azizi, Michel, Boulanger, Marion, Bruno, Rosa M., De Leeuw, Peter, Fendrikova-Mahlay, Natalia, Froehlich, James et al. · 2019 · Journal of Hypertension
Genetic Liability to Depression and Risk of Coronary Artery Disease, Myocardial Infarction, and Other Cardiovascular Outcomes
Yunlong Lu, Zhen Wang, Marios K. Georgakis, Hefeng Lin, Liangrong Zheng · 2020 · Journal of the American Heart Association
Methylation‐based estimated biological age and cardiovascular disease
Lars Lind, Erik Ingelsson, Johan Sundström, Agneta Siegbahn, Erik Lampa · 2017 · European Journal of Clinical Investigation
Predicting gene targets from integrative analyses of summary data from GWAS and eQTL studies for 28 human complex traits
Pavlides, Jennifer M. Whitehead, Zhu, Zhihong, Gratten, Jacob, McRae, Allan F., Wray, Naomi R., Yang, Jian · 2016 · Genome Medicine
Biological Insights Into Muscular Strength: Genetic Findings in the UK Biobank
Emmi Tikkanen, Stefan Gustafsson, David Amar, Anna Shcherbina, Daryl M. Waggott, Euan Angus Ashley, Erik Ingelsson · 2018 · Scientific Reports
Large-scale genome-wide enrichment analyses identify new trait-associated genes and pathways across 31 human phenotypes
Xiang Zhu, Matthew Stephens · 2018 · Nature Communications
Transethnic Meta-Analysis of Genome-Wide Association Studies Identifies Three New Loci and Characterizes Population-Specific Differences for Coronary Artery Disease
Hiroshi Matsunaga, Kaoru Ito, Masato Akiyama, Atsushi Takahashi, Satoshi Koyama, Seitaro Nomura, Hirotaka Ieki, Kouichi Ozaki, Yoshihiro Onouchi, Saori Sakaue et al. · 2020 · Circulation Genomic and Precision Medicine
Multi-omics approaches for revealing the complexity of cardiovascular disease
Stephen F. Doran, Muhammad Arif, Simon C.C. Lam, Abdulahad Bayraktar, Hasan Türkez, Mathias Uhlén, Jan Borén, Adil Mardinoğlu · 2021 · Briefings in Bioinformatics
Predicting causal variants affecting expression by using whole-genome sequencing and RNA-seq from multiple human tissues
Andrew Anand Brown, Ana Viñuela, Olivier Delaneau, Tim D. Spector, Kerrin S. Small, Emmanouil T. Dermitzakis · 2017 · Nature Genetics
Highly multiplexed rapid DNA detection with single-nucleotide specificity via convective PCR in a portable device
Dmitriy A. Khodakov, Jiaming Li, Jinny Xuemeng Zhang, David Yu Zhang · 2021 · Nature Biomedical Engineering
Independent Causal Effect of Remnant Cholesterol on Atherosclerotic Cardiovascular Outcomes: A Mendelian Randomization Study
Navarese, Eliano P., Vine, Donna, Proctor, Spencer, Grzelakowska, Klaudyna, Berti, Sergio, Kubica, Jacek, Raggi, Paolo · 2023 · Arteriosclerosis, Thrombosis, and Vascular Biology
A decade in psychiatric GWAS research
Tanya B. Horwitz, Katie Lam, Yu Chen, Yan Xia, Chunyu Liu · 2018 · Molecular Psychiatry
Association of physical activity, sedentary behaviours and sleep duration with cardiovascular diseases and lipid profiles: a Mendelian randomization analysis
Zhenhuang Zhuang, Meng Qiu Gao, Ruotong Yang, Nan Li, Zhonghua Liu, Weihua Cao, Tao Huang · 2020 · Lipids in Health and Disease
Chromosome 1q21.2 and additional loci influence risk of spontaneous coronary artery dissection and myocardial infarction
Jacqueline Saw, Min‐Lee Yang, Mark Trinder, Catherine Tcheandjieu, Chang Xu, Andrew Starovoytov, Isabelle Birt, Michael R. Mathis, Kristina L. Hunker, Ellen M. Schmidt et al. · 2020 · Nature Communications
Long Noncoding RNA ANRIL: Lnc-ing Genetic Variation at the Chromosome 9p21 Locus to Molecular Mechanisms of Atherosclerosis
Lesca Miriam Holdt, Daniel Teupser · 2018 · Frontiers in Cardiovascular Medicine
High resolution genetic mapping of putative causal interactions between regions of open chromatin
N. Kumasaka, A. Knights, D. Gaffney · 2018 · Nature Genetics
The novel coronary artery disease risk gene JCAD/KIAA1462 promotes endothelial dysfunction and atherosclerosis
Suowen Xu, Yanni Xu, Peng Liu, Shuya Zhang, Huan Liu, Spencer A. Slavin, Sandeep Kumar, Marina Koroleva, Jinque Luo, Xiaoqian Wu et al. · 2019 · European Heart Journal
Phenome-wide investigation of health outcomes associated with genetic predisposition to loneliness
Abdel Abdellaoui, Sandra Sanchez‐Roige, Julia Sealock, Jorien L. Treur, Jessica Kiri Dennis, Pierre Fontanillas, Sarah L. Elson, Michel Guillaume Nivard, Hill Fung Ip, Matthijs D. van der Zee et al. · 2019 · Human Molecular Genetics