Inhibition of mTOR induces autophagy and reduces toxicity of polyglutamine expansions in fly and mouse models of Huntington disease

Cited by (1,011)

Items 501–600 of 1,011

1. Bioenergetic flux, mitochondrial mass and mitochondrial morphology dynamics in AD and MCI cybrid cell lines
   Silva, D. F., Selfridge, J. E., Lu, J., E, L., Roy, N., Hutfles, L., Burns, J. M., Michaelis, E. K., Yan, S., Cardoso, S. M. et al. · 2013 · Human Molecular Genetics
2. Emerging connections between RNA and autophagy
   Lisa B. Frankel, Michał Lubas, Anders Henrik Lund · 2016 · Autophagy
3. Role of molecular chaperones in neurodegenerative disorders
   Anatoli B. Meriin, Michael Y. Sherman · 2005 · International Journal of Hyperthermia
4. Parkin-mediated ubiquitin signalling in aggresome formation and autophagy
   Lih‐Shen Chin, James A. Olzmann, Lian Li · 2010 · Biochemical Society Transactions
5. Oligonucleotide therapeutic approaches for Huntington disease
   Dinah W.Y. Sah, Neil Aronin M. D · 2011 · Journal of Clinical Investigation
6. Mitochondrial autophagy in neural function, neurodegenerative disease, neuron cell death, and aging
   Yakup Batlevi, Albert R. La Spada · 2010 · Neurobiology of Disease
7. Metformin attenuates diabetes-induced tau hyperphosphorylation in vitro and in vivo by enhancing autophagic clearance
   Jinliang Chen, Cheng Luo, Die Pu, Guoqiang Zhang, Yuxing Zhao, Yue Sun, Kexiang Zhao, Zhiyin Liao, Ankang Lv, Shiyu Zhu et al. · 2018 · Experimental Neurology
8. Herpes simplex virus type I induces the accumulation of intracellular β-amyloid in autophagic compartments and the inhibition of the non-amyloidogenic pathway in human neuroblastoma cells
   Soraya Santana, Marı́a Recuero, Maria Jesus Bullido, Fernando Valdivieso, Jesús Aldudo · 2011 · Neurobiology of Aging
9. HIV-1 Inhibits Autophagy in Bystander Macrophage/Monocytic Cells through Src-Akt and STAT3
   Jennifer Van Grol, Maria Cecilia Subauste, Rosa M. Andrade, Koh Fujinaga, Julie A. E. Nelson, Carlos S. Subauste · 2010 · PLoS ONE
10. SOD1 and TDP-43 animal models of amyotrophic lateral sclerosis: recent advances in understanding disease toward the development of clinical treatments
    Peter I. Joyce, Pietro Fratta, Elizabeth Fisher, Abraham Acevedo‐Arozena · 2011 · Mammalian Genome
11. Targets for future clinical trials in Huntington's disease: What's in the pipeline?
    Edward J. Wild, Sarah J. Tabrizi · 2014 · Movement Disorders
12. Role of Protein Misfolding and Proteostasis Deficiency in Protein Misfolding Diseases and Aging
    Karina Cuanalo-Contreras, Abhisek Mukherjee, Claudio A. Soto · 2013 · International Journal of Cell Biology
13. The pathophysiological mechanisms underlying diabetic retinopathy
    Lindan Wei, Xin Sun, Chenxi Fan, Rongli Li, Shuanglong Zhou, Hongsong Yu · 2022 · Frontiers in Cell and Developmental Biology
14. Antidepressive-like effects of rapamycin in animal models: Implications for mTOR inhibition as a new target for treatment of affective disorders
    Caitlin Cleary, J.A.S. Linde, K.M. Hiscock, Itay Hadas, Robert Haim Belmaker, Galila Agam, Shlomit Flaisher-Grinberg, Haim Einat · 2008 · Brain Research Bulletin
15. Autophagy - An Emerging Anti-Aging Mechanism?
    Malene Hansen · 2012 · Journal of Clinical & Experimental Pathology
16. Felodipine induces autophagy in mouse brains with pharmacokinetics amenable to repurposing
    Farah H. Siddiqi, Fiona M. Menzies, Ana López, Eleanna Stamatakou, Cansu Karabiyik, Rodrigo Portes Ureshino, Thomas Ricketts, María Jiménez-Sánchez, Miguel Angel Esteban, Liangxue Lai et al. · 2019 · Nature Communications
17. Microglial-to-neuronal CCR5 signaling regulates autophagy in neurodegeneration
    Festa, Beatrice Paola, Siddiqi, Farah H., Jimenez-Sanchez, Maria, Won, Hyeran, Rob, Matea, Djajadikerta, Alvin, Stamatakou, Eleanna, Rubinsztein, David C. · 2023 · Neuron
18. β‐Amyloid is a substrate of autophagy in sporadic inclusion body myositis
    Jan D. Lünemann, Jens Schmidt, Dorothee Schmid, K Barthel, Arne Wrede, Marinos C. Dalakas, Christian Münz · 2007 · Annals of Neurology
19. Nutrient Deprivation Induces Neuronal Autophagy and Implicates Reduced Insulin Signaling in Neuroprotective Autophagy Activation
    Jessica E. Young, Refugio A. Martinez, Albert R. La Spada · 2008 · Journal of Biological Chemistry
20. Protein misfolding disorders and macroautophagy
    Menzies, Fiona M, Moreau, Kevin, Rubinsztein, David C · 2011 · Current Opinion in Cell Biology
21. Rapamycin treatment for amyotrophic lateral sclerosis: Protocol for a phase II randomized, double-blind, placebo-controlled, multicenter, clinical trial (RAP-ALS trial)
    Mandrioli, Jessica, D’Amico, Roberto, Zucchi, Elisabetta, Gessani, Annalisa, Fini, Nicola, Fasano, Antonio, Caponnetto, Claudia, Chiò, Adriano, Dalla Bella, Eleonora, Lunetta, Christian et al. · 2018 · Medicine
22. Consensus Paper: Pathological Mechanisms Underlying Neurodegeneration in Spinocerebellar Ataxias
    Antoni Matilla‐Dueñas, Tetsuo Ashizawa, Alexis Brice, Stefania Magri, Karen N. McFarland, Massimo Pandolfo, Stefan M. Pulst, Olaf Rieß, David Chaim Rubinsztein, Jana Schmidt et al. · 2013 · The Cerebellum
23. Sulforaphane enhances proteasomal and autophagic activities in mice and is a potential therapeutic reagent for Huntington's disease
    Yanying Liu, Casey L. Hettinger, Dong Zhang, Khosrow S. Rezvani, Xuejun Wang, Hongmin Wang · 2014 · Journal of Neurochemistry
24. Tauopathy: A common mechanism for neurodegeneration and brain aging
    Pampa Saha, Nilkantha Sen · 2019 · Mechanisms of Ageing and Development
25. Alterations in degradative pathways and protein aggregation in a neuropathy model based on PMP22 overexpression
    Jenny Fortun, Jocelyn C. Go, Jie Li, Stephanie A. Amici, William A. Dunn, Lucia M. Notterpek · 2005 · Neurobiology of Disease
26. Measurement of autophagy flux in the nervous system in vivo
    Castillo, K, Valenzuela, V, Matus, S, Nassif, M, Oñate, M, Fuentealba, Y, Encina, G, Irrazabal, T, Parsons, G, Court, F A et al. · 2013 · Cell Death & Disease
27. Pathophysiology of Huntingtonʼs disease: from huntingtin functions to potential treatments
    Emmanuel Flamand Roze, Frédéric Saudou, Jocelyne Caboche · 2008 · Current Opinion in Neurology
28. Thinking globally and acting locally with TOR
    Andrew M. Arsham, Thomas P. Neufeld · 2006 · Current Opinion in Cell Biology
29. Autophagy deregulation in neurodegenerative diseases – recent advances and future perspectives
    Zelda H. Cheung, Nancy Y. Ip · 2011 · Journal of Neurochemistry
30. Pathophysiological importance of aggregated damaged proteins
    Annika Höhn, Tobias Jung, Tilman Grune · 2014 · Free Radical Biology and Medicine
31. Autophagy in neurodegeneration and development
    Ashley R. Winslow, David Chaim Rubinsztein · 2008 · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease
32. Autophagy activation by rapamycin eliminates mouse Mallory-Denk bodies and blocks their proteasome inhibitor-mediated formation
    Masaru Harada, Shinichiro Hanada, Diana M. Toivola, Nafisa Ghori, M. Bishr Omary · 2008 · Hepatology
33. Early autophagic response in a novel knock-in model of Huntington disease
    Mary Y. Heng, Duy Kevin Duong, Roger L. Albin, Sara J. Tallaksen‐Greene, Jesse M. Hunter, Mathieu J. Lesort, Alex Osmand, Henry Lauris Paulson, Peter J. Detloff · 2010 · Human Molecular Genetics
34. Dual Role of Autophagy in Diseases of the Central Nervous System
    Tamara Bar-Yosef, Odeya Damri, Galila Agam · 2019 · Frontiers in Cellular Neuroscience
35. Regulated cell death: discovery, features and implications for neurodegenerative diseases
    Juntao Cui, Suhan Zhao, Yinghui Li, Danyang Zhang, Bingjing Wang, Junxia Xie, Jun Wang · 2021 · Cell Communication and Signaling
36. Vacuolin-1 potently and reversibly inhibits autophagosome-lysosome fusion by activating RAB5A
    Yingying Lü, Shichen Dong, Baixia Hao, Chang Li, Kaiyuan Zhu, Wenjing Guo, Qian Wang, King‐Ho Cheung, Connie W.M. Wong, Wutian Wu et al. · 2014 · Autophagy
37. Rhes, a Striatal-selective Protein Implicated in Huntington Disease, Binds Beclin-1 and Activates Autophagy
    Mealer, Robert G., Murray, Alexandra J., Shahani, Neelam, Subramaniam, Srinivasa, Snyder, Solomon H. · 2014 · Journal of Biological Chemistry
38. Inhibition of Autophagy Induction Delays Neuronal Cell Loss Caused by Dysfunctional ESCRT-III in Frontotemporal Dementia
    Jin‐A Lee, Fen‐Biao Gao · 2009 · Journal of Neuroscience
39. HDAC6 at the Intersection of Autophagy, the Ubiquitin-proteasome System, and Neurodegeneration
    Udai Bhan Pandey, Yakup Batlevi, Eric H. Baehrecke, J. Paul Taylor · 2007 · Autophagy
40. Chemical Composition of Solanum nigrum Linn Extract and Induction of Autophagy by Leaf Water Extract and Its Major Flavonoids in AU565 Breast Cancer Cells
    Hsiu‐Chen Huang, Kai-Yang Syu, Jen‐Kun Lin · 2010 · Journal of Agricultural and Food Chemistry
41. The role of amyloid oligomers in neurodegenerative pathologies
    Cameron Wells, Samuel E. Brennan, Matthew Keon, Lezanne Ooi · 2021 · International Journal of Biological Macromolecules
42. HspB8 Participates in Protein Quality Control by a Non-chaperone-like Mechanism That Requires eIF2α Phosphorylation
    Serena Carra, Jeanette F. Brunsting, Herman Lambert, Jacques Landry, Harm H. Kampinga · 2008 · Journal of Biological Chemistry
43. Decreased Insulin-Receptor Signaling Promotes the Autophagic Degradation of β-Amyloid Peptide inC. elegans
    Maria L. Florez‐McClure, Lindsay A. Hohsfield, Gin Fonte, Matthew T. Bealor, Christopher D. Link · 2007 · Autophagy
44. Desmethylclomipramine induces the accumulation of autophagy markers by blocking autophagic flux
    Mario Rossi, Eliana Rosa Munarriz, Stefano Bartesaghi, Marco Milanese, Dr David Dinsdale, Maria Guerra Martin, Edward T. W. Bampton, Paul Glynn, Giambattista Bonanno, Richard A. Knight et al. · 2009 · Journal of Cell Science
45. Huntington disease
    2018 · Handbook of Clinical Neurology
46. Rapamycin increases neuronal survival, reduces inflammation and astrocyte proliferation after spinal cord injury
    Yona Goldshmit, Sivan Kanner, Maria Zacs, Frisca Frisca, Alexander Ruvantha Pinto, Peter David Currie, Ronit Pinkas‐Kramarski · 2015 · Molecular and Cellular Neuroscience
47. How longevity research can lead to therapies for Alzheimer's disease: The rapamycin story
    Arlan G Richardson, Verónica Galván, Ai‐Ling Lin, Salvatore Oddo · 2014 · Experimental Gerontology
48. Iron dysregulation in Huntington's disease
    Michelle Müller, Blair R. Leavitt · 2014 · Journal of Neurochemistry
49. The mTOR Inhibitor Rapamycin Mitigates Perforant Pathway Neurodegeneration and Synapse Loss in a Mouse Model of Early-Stage Alzheimer-Type Tauopathy
    Robert Siman, R. Cocca, Yina Dong · 2015 · PLoS ONE
50. Heat shock proteins as gatekeepers of proteolytic pathways—Implications for age-related macular degeneration (AMD)
    Kai Kaarniranta, Antero Salminen, Eeva‐Liisa Eskelinen, Jürgen Kopitz · 2009 · Ageing Research Reviews
51. Drosophila models of neurodegenerative disease
    Tzu‐Kang Sang, George R. Jackson · 2005 · NeuroRx
52. Autophagy signaling in cancer and its potential as novel target to improve anticancer therapy
    Luigi Moretti, Eddy Shih-Hsin Yang, Kwang W. Kim, Jiahong Lu · 2007 · Drug Resistance Updates
53. The Role of Ubiquitin in Autophagy-Dependent Protein Aggregate Processing
    Tso‐Pang Yao · 2010 · Genes & Cancer
54. Autophagy in Age-Associated Neurodegeneration
    Athanasios Metaxakis, Christina Ploumi, Nektarios Tavernarakis · 2018 · Cells
55. Autophagy in Drosophila melanogaster
    Christina S. Kary, Eric H. Baehrecke · 2009 · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research
56. Wnt/β-catenin signaling pathway induces autophagy-mediated temozolomide-resistance in human glioblastoma
    Eun-Jin Yun, Sangwoo Kim, Jer‐Tsong Hsieh, Seung Tae Baek · 2020 · Cell Death and Disease
57. Neuropathogenesis-on-chips for neurodegenerative diseases
    Sarnai Amartumur, Huong Mai Nguyen, Thuy Huynh, Testaverde S. Kim, Ran‐Sook Woo, Eungseok Oh, Kyeong Kyu Kim, Luke P. Lee, Chaejeong Heo · 2024 · Nature Communications
58. Pten ablation in adult dopaminergic neurons is neuroprotective in Parkinson's disease models
    Andrii Domanskyi, Christin Geißler, Ilya A. Vinnikov, Heike Alter, Andreas Schober, Miriam Annika Vogt, Peter Gass, Rosanna Parlato, Günther Schütz · 2011 · The FASEB Journal
59. Rapamycin Inhibits Polyglutamine Aggregation Independently of Autophagy by Reducing Protein Synthesis
    King, Matthew A., Hands, Sarah, Hafiz, Farida, Mizushima, Noboru, Tolkovsky, Aviva M., Wyttenbach, Andreas · 2008 · Molecular Pharmacology
60. Axonal degeneration as a therapeutic target in the CNS
    Lingor, Paul, Koch, Jan C., Tönges, Lars, Bähr, Mathias · 2012 · Cell and Tissue Research
61. TOR on the brain
    Michael G. Garelick, Brian Keith Kennedy · 2010 · Experimental Gerontology
62. A Critical Kinase Cascade In Neurological Disorders: Pi3K, Akt and Mtor
    Zhao Zhong Chong, Yan Shang, Shaohui Wang, Kenneth Maiese · 2012 · Future Neurology
63. Neuronal autophagy: a housekeeper or a fighter in neuronal cell survival?
    Lee, Jin-A · 2012 · Experimental Neurobiology
64. Shedding new light on neurodegenerative diseases through the mammalian target of rapamycin
    Chong, Zhao Zhong, Shang, Yan Chen, Wang, Shaohui, Maiese, Kenneth · 2012 · Progress in Neurobiology
65. Temsirolimus attenuates tauopathy in vitro and in vivo by targeting tau hyperphosphorylation and autophagic clearance
    Teng Jiang, Jin‐Tai Yu, Xi‐Chen Zhu, Qiao-Quan Zhang, Lei Cao, Hui-Fu Wang, Meng‐Shan Tan, Qing Gao, Hao Qin, Yingdong Zhang et al. · 2014 · Neuropharmacology
66. A152T tau allele causes neurodegeneration that can be ameliorated in a zebrafish model by autophagy induction
    Ana López, Suzee E. Lee, Kevin J. Wojta, Eliana Marisa Ramos, Eric Klein, Jason Chen, Adam L. Boxer, Maria Luisa Gorno‐Tempini, Daniel H. Geschwind, Lars Schlotawa et al. · 2017 · Brain
67. Rapamycin reduces intrahepatic alpha-1-antitrypsin mutant Z protein polymers and liver injury in a mouse model
    Shalesh Kaushal, Mani Annamali, Keith Blomenkamp, David A. Rudnick, Donna R. Halloran, Elizabeth M. Brunt, Jeffrey H. Teckman · 2010 · Experimental Biology and Medicine
68. Novel therapeutic strategies for the treatment of protein-misfolding diseases
    Jean‐Christophe Rochet · 2007 · Expert Reviews in Molecular Medicine
69. Calpain inhibition mediates autophagy-dependent protection against polyglutamine toxicity
    Fiona M. Menzies, Moisés Garcı́a-Arencibia, Sara Imarisio, Niamh C. O’Sullivan, T Ricketts, Brianne A. Kent, Mala V. Rao, W Lam, Zeyn W. Green-Thompson, Ralph A. Nixon et al. · 2014 · Cell Death and Differentiation
70. Potentiation of Amyotrophic Lateral Sclerosis (ALS)-associated TDP-43 Aggregation by the Proteasome-targeting Factor, Ubiquilin 1
    Sang Hwa Kim, Yuling Shi, Keith A. Hanson, Leah M. Williams, Ryo Sakasai, Michael J. Bowler, Randal S. Tibbetts · 2008 · Journal of Biological Chemistry
71. Altered distribution of ATG9A and accumulation of axonal aggregates in neurons from a mouse model of AP-4 deficiency syndrome
    Raffaella De Pace, Miguel Skirzewski, Markus Daμμe, Rafael Mattera, Jeffrey C. Mercurio, Arianne M. Foster, Loreto Cuitiño, Michal Jarník, Victoria J. Hoffmann, H Douglas Morris et al. · 2018 · PLoS Genetics
72. Pleiotropic Effects of mTOR and Autophagy During Development and Aging
    Kathrin Schmeißer, J. Alex Parker · 2019 · Frontiers in Cell and Developmental Biology
73. ω-6 Polyunsaturated fatty acids (linoleic acid) activate both autophagy and antioxidation in a synergistic feedback loop via TOR-dependent and TOR-independent signaling pathways
    Bo Yang, Yan Zhou, Mengjiao Wu, Xueshan Li, Kangsen Mai, Qinghui Ai · 2020 · Cell Death and Disease
74. Quality Control Against Misfolded Proteins in the Cytosol: A Network for Cell Survival
    HIROSHI Y. KUBOTA · 2009 · The Journal of Biochemistry
75. LRRK2 Kinase Regulates Synaptic Morphology through Distinct Substrates at the Presynaptic and Postsynaptic Compartments of theDrosophilaNeuromuscular Junction
    Seongsoo Lee, Hsin‐Ping Liu, Wei‐Yong Lin, Hui-Fu Guo, Bingwei Lu · 2010 · Journal of Neuroscience
76. How and why to study autophagy in Drosophila: It’s more than just a garbage chute
    Nagy, Péter, Varga, Ágnes, Kovács, Attila L., Takáts, Szabolcs, Juhász, Gábor · 2015 · Methods
77. Autophagosome dynamics in neurodegeneration at a glance
    Yvette C. Wong, Erika L.F. Holzbaur · 2015 · Journal of Cell Science
78. Autophagy Activator Drugs: A New Opportunity in Neuroprotection from Misfolded Protein Toxicity
    Stefano Thellung, Alessandro Corsaro, Mario Nizzari, Federica Barbieri, Tullio Florio · 2019 · International Journal of Molecular Sciences
79. mTOR inhibition modulates epileptogenesis, seizures and depressive behavior in a genetic rat model of absence epilepsy
    Emilio Russo, Rita Citraro, Giuseppe Donato, Caterina Camastra, Rodolfo Iuliano, Salvatore Cuzzocrea, Andrew Constanti, Giovambattista De Sarro · 2012 · Neuropharmacology
80. Regulation and Roles of Autophagy at Synapses
    Vassiliki Nikoletopoulou, Nektarios Tavernarakis · 2018 · Trends in Cell Biology
81. DNA methylation dynamics and dysregulation delineated by high-throughput profiling in the mouse
    Wanding Zhou, Toshinori Hinoue, Bret Barnes, Owen D. Mitchell, Waleed Iqbal, Sol Moe Lee, Kelly K. Foy, Kwang‐Ho Lee, Ethan Jacob Moyer, Alexandra VanderArk et al. · 2022 · Cell Genomics
82. Navigating the landscape of protein folding and proteostasis: from molecular chaperones to therapeutic innovations
    Omer F. Kuzu, Lars Jørgen Tvenge Granerud, Fahri Saatcioglu · 2025 · Signal Transduction and Targeted Therapy
83. Suppression of autophagy precipitates neuronal cell death following low doses of methamphetamine
    Castino, Roberta, Lazzeri, Gloria, Lenzi, Paola, Bellio, Natascia, Follo, Carlo, Ferrucci, Michela, Fornai, Francesco, Isidoro, Ciro · 2008 · Journal of Neurochemistry
84. The histone deacetylase inhibitors LAQ824 and LBH589 do not require death receptor signaling or a functional apoptosome to mediate tumor cell death or therapeutic efficacy
    Leigh Ellis, Michael L Bots, Ralph K. Lindemann, Jessica E. Bolden, Andrea Newbold, Leonie A. Cluse, Clare L. Scott, Andreas Strasser, Peter Wisdom Atadja, Scott W. Lowe et al. · 2009 · Blood
85. Functional Significance and Morphological Characterization of Starvation-Induced Autophagy in the Adult Heart
    Hiromitsu Kanamori, Genzou Takemura, Rumi Maruyama, Kazuko Goto, Akiko Tsujimoto, Atsushi Ogino, Longhu Li, Itta Kawamura, Toshiaki Takeyama, Tomonori Kawaguchi et al. · 2009 · American Journal Of Pathology
86. Reversible Disruption of Dynactin 1-Mediated Retrograde Axonal Transport in Polyglutamine-Induced Motor Neuron Degeneration
    Masahisa Katsuno, Hiroaki Adachi, Makoto Minamiyama, Masahiro Waza, Keisuke Tokui, Haruhiko Banno, Keisuke Suzuki, Yu Onoda, Fumiaki Tanaka, Manabu Doyu et al. · 2006 · Journal of Neuroscience
87. Rapamycin reduces severity of senile osteoporosis by activating osteocyte autophagy
    D. Luo, Hui Jun Ren, Tingdong Li, K. Lian, Dasheng Lin · 2015 · Osteoporosis International
88. Autophagy: A Lysosome-Dependent Process with Implications in Cellular Redox Homeostasis and Human Disease
    Stefan W. Ryter, Divya Bhatia, Mary E. Choi · 2018 · Antioxidants and Redox Signaling
89. Mallory–Denk-bodies: Lessons from keratin-containing hepatic inclusion bodies
    Pavel Strnad, Kurt Zatloukal, Cornelia Stumptner, Hasan Kulaksiz, Helmut Denk · 2008 · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease
90. Emerging roles of molecular chaperones and co-chaperones in selective autophagy: focus on BAG proteins
    Martin Gamerdinger, Serena Carra, Christian Behl · 2011 · Journal of Molecular Medicine
91. Ischemia-Reperfusion Injury in Aged Livers—The Energy Metabolism, Inflammatory Response, and Autophagy
    Chunyi Kan, Luisa Ungelenk, Amelie Lupp, Olaf Dirsch, Uta Dahmen · 2017 · Transplantation
92. XBP-1u suppresses autophagy by promoting the degradation of FoxO1 in cancer cells
    Ying Zhao, Xue Li, Mu-Yan Cai, Ke Ma, Jing Hui Yang, Jingyi Zhou, Wan Fu, Fu-Zheng Wei, Lina Wang, Dan Xie et al. · 2013 · Cell Research
93. Fighting disease by selective autophagy of aggregate‐prone proteins
    Helene Knævelsrud, Anne Simonsen · 2010 · FEBS Letters
94. The spectrum of neurodevelopmental, neuromuscular and neurodegenerative disorders due to defective autophagy
    Celine Deneubourg, Mauricio Ramm, Luke J. Smith, Olga Baron, Kritarth Singh, Susan Byrne, Michael R. Duchen, Mathias Gautel, Eeva‐Liisa Eskelinen, Manolis Fanto et al. · 2021 · Autophagy
95. Huntingtin and Mutant SOD1 Form Aggregate Structures with Distinct Molecular Properties in Human Cells
    Gen Matsumoto, Soojin Kim, Richard I. Morimoto · 2005 · Journal of Biological Chemistry
96. Rapamycin Causes Upregulation of Autophagy and Impairs Islets Function Both In Vitro and In Vivo
    Masahiro Tanemura, Y. Ohmura, Takashi Deguchi, Tomohisa MACHIDA, R. Tsukamoto, H. Wada, Shogo Kobayashi, Shigeru Marubashi, Hidetoshi Eguchi, Tomonobu Ito et al. · 2011 · American Journal of Transplantation
97. Proteostasis in Huntington's disease: disease mechanisms and therapeutic opportunities
    Rachel Harding, Yufeng Tong · 2018 · Acta Pharmacologica Sinica
98. A small GTPase, human Rab32, is required for the formation of autophagic vacuoles under basal conditions
    Yuko Hirota, Yoshitaka Tanaka · 2009 · Cellular and Molecular Life Sciences
99. Huntingtin promotes mTORC1 signaling in the pathogenesis of Huntington’s disease
    William M. Pryor, Marta Biagioli, Neelam Shahani, Supriya Swarnkar, Wen‐Chin Huang, Damon T. Page, Marcy E. MacDonald, Srinivasa Subramaniam · 2014 · Science Signaling
100. Autophagy, Prion Infection and their Mutual Interactions
     Andreas Heiseke, Yasmine Aguib, Hermann M. Schätzl · 2010 · Caister Academic Press eBooks